Effect of acetazolamide vs placebo on duration of invasive mechanical ventilation among patients with chronic obstructive pulmonary disease: A randomized clinical trial

JAMA - Journal of the American Medical Association

Volumn 315, Issue 5, 2016, Pages 480-488

  Faisy, Christophe ^a   Meziani, Ferhat ^b   Planquette, Benjamin ^c   Clavel, Marc ^d   Gacouin, Arnaud ^e   Bornstain, Caroline ^f   Schneider, Francis ^g   Duguet, Alexandre ^h   Gibot, Sébastien ⁱ   Lerolle, Nicolas ^j   Ricard, Jean Damien ^k   Sanchez, Olivier ^a   Djibre, Michel ^l   Ricome, Jean Louis ^m   Rabbat, Antoine ⁿ   Heming, Nicholas ^a   Urien, Saïk ⁿ   Esvan, Maxime ^a   Katsahian, Sandrine ^a  

^a HÔPITAL EUROPÉEN GEORGES POMPIDOU   (France)

^b HÔPITAL CIVIL   (France)

^c CENTRE HOSPITALIER DE VERSAILLES   (France)

^d LIMOGES UNIVERSITY HOSPITAL   (France)

^e RENNES UNIVERSITY HOSPITAL   (France)

^f Cardiology Department   (France)

^g Neurosurgery Hospital Hautepierre   (France)

^h PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

ⁱ UNIVERSITY HOSPITAL OF NANCY   (France)

^j ANGERS UNIVERSITY HOSPITAL   (France)

^k HÔPITAL LOUIS MOURIER   (France)

^l HÔPITAL TENON   (France)

^m CENTRE HOSPITALIER INTERCOMMUNAL   (France)

ⁿ Institut Cochin   (France)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ACETAZOLAMIDE; BICARBONATE; PLACEBO; CARBON DIOXIDE; CARBONATE DEHYDRATASE INHIBITOR;

ADULT; AGED; ARTERIAL CARBON DIOXIDE TENSION; ARTERIAL GAS; ARTICLE; ARTIFICIAL VENTILATION; BICARBONATE BLOOD LEVEL; BREATHING RATE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CONTROLLED STUDY; CRITICALLY ILL PATIENT; DOUBLE BLIND PROCEDURE; DRUG EFFECT; ENDOTRACHEAL INTUBATION; EXTUBATION; FEMALE; FRANCE; HOSPITAL MORTALITY; HUMAN; INTENSIVE CARE UNIT; INTENTION TO TREAT ANALYSIS; LENGTH OF STAY; LUNG MINUTE VOLUME; MAJOR CLINICAL STUDY; MALE; METABOLIC ALKALOSIS; MULTICENTER STUDY; OUTCOME ASSESSMENT; RANDOMIZED CONTROLLED TRIAL; TIDAL VOLUME; TRACHEOTOMY; TREATMENT DURATION; VENTILATOR WEANING; ALKALOSIS, RESPIRATORY; BLOOD; CLINICAL TRIAL; PROCEDURES; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; STATISTICS AND NUMERICAL DATA; TIME; TREATMENT OUTCOME;

ACETAZOLAMIDE; AGED; ALKALOSIS, RESPIRATORY; BICARBONATES; CARBON DIOXIDE; CARBONIC ANHYDRASE INHIBITORS; DOUBLE-BLIND METHOD; FEMALE; HUMANS; INTENTION TO TREAT ANALYSIS; MALE; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RESPIRATION, ARTIFICIAL; TIME FACTORS; TREATMENT OUTCOME; VENTILATOR WEANING;

EID: 84957790394     PISSN: 00987484     EISSN: 15383598     Source Type: Journal    
DOI: 10.1001/jama.2016.0019     Document Type: Article

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