Population pharmacodynamic modeling and simulation of the respiratory effect of acetazolamide in decompensated COPD patients

PLoS ONE

Volumn 9, Issue 1, 2014, Pages

  Heming, Nicholas ^a   Urien, Saïk ^b   Fulda, Virginie ^a   Meziani, Ferhat ^c   Gacouin, Arnaud ^d   Clavel, Marc ^e   Planquette, Benjamin ^f   Faisy, Christophe ^a  

^a HÔPITAL EUROPÉEN GEORGES POMPIDOU   (France)

^b Paris Descartes University   (France)

^c HÔPITAL CIVIL   (France)

^d PONTCHAILLOU UNIVERSITY HOSPITAL   (France)

^e LIMOGES UNIVERSITY HOSPITAL   (France)

^f CENTRE HOSPITALIER DE VERSAILLES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ACETAZOLAMIDE;

ARTICLE; ARTIFICIAL VENTILATION; BLOOD CARBON DIOXIDE TENSION; BREATHING RATE; CHRONIC OBSTRUCTIVE LUNG DISEASE; COHORT ANALYSIS; DOSE RESPONSE; DRUG EFFECT; FEMALE; HUMAN; LUNG MINUTE VOLUME; MAJOR CLINICAL STUDY; MALE; METABOLIC ALKALOSIS; RESPIRATORY FUNCTION; SIMULATION; TIDAL VOLUME; TREATMENT RESPONSE;

ACETAZOLAMIDE; COMPUTER SIMULATION; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; MODELS, BIOLOGICAL; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RESPIRATION; RESPIRATION, ARTIFICIAL; TIDAL VOLUME;

EID: 84898490026     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0086313     Document Type: Article

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