Mice null for NEDD9 (HEF1) display extensive hippocampal dendritic spine loss and cognitive impairment

Brain Research

Volumn 1632, Issue , 2016, Pages 141-155

  Knutson, D C ^a   Mitzey, A M ^a   Talton, L E ^b   Clagett Dame, M ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

CAS; Dendritic spine density; Hippocampus; NEDD9; Null mutant; Retinoic acid induced differentiation

Indexed keywords

CRK ASSOCIATED SUBSTRATE PROTEIN; NEDD9 PROTEIN; UNCLASSIFIED DRUG; NEDD9 PROTEIN, MOUSE; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ADHESION; CELL DENSITY; CELL DIFFERENTIATION; CELL LOSS; CELL MIGRATION; CELL PROLIFERATION; COGNITIVE DEFECT; CONTROLLED STUDY; DENDRITIC SPINE; DENTATE GYRUS; DNA SEQUENCE; EMBRYO; HIPPOCAMPAL CA1 REGION; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; LOXP SITE; MORRIS WATER MAZE TEST; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; SOUTHERN BLOTTING; SPATIAL LEARNING; STEREOMETRY; WESTERN BLOTTING; ANIMAL; C57BL MOUSE; DEFICIENCY; FEMALE; GENE TARGETING; KNOCKOUT MOUSE; MALE; METABOLISM; PATHOLOGY;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; COGNITION DISORDERS; DENDRITIC SPINES; FEMALE; GENE KNOCK-IN TECHNIQUES; HIPPOCAMPUS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT;

EID: 84957710574     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2015.12.005     Document Type: Article

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