Spinal glial activation and oxidative stress are alleviated by treatment with curcumin or coenzyme Q in sickle mice

Haematologica

Volumn 101, Issue 2, 2016, Pages e44-e47

  Valverde, Yessenia ^a   Benson, Barbara ^a   Gupta, Mihir ^b   Gupta, Kalpna ^a  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Astrocyte; CoQ10; Curcumin; Glial; Pain; Sickle cell anemia

Indexed keywords

CURCUMIN; GLIAL FIBRILLARY ACIDIC PROTEIN; REACTIVE OXYGEN METABOLITE; SUBSTANCE P; UBIQUINONE; ANTIOXIDANT; GLIAL FIBRILLARY ASTROCYTIC PROTEIN, MOUSE; NEUROPEPTIDE; NEUROPEPTIDE S, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ASTROCYTE; CELL ACTIVATION; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; FEMALE; GLIA CELL; HEAT SENSITIVITY; LETTER; MALE; MECHANICAL HYPERALGESIA; MOUSE; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; OXIDATIVE STRESS; SICKLE CELL ANEMIA; ANIMAL; ANTAGONISTS AND INHIBITORS; COMPLICATION; DISEASE MODEL; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HUMAN; HYPERALGESIA; METABOLISM; MICROGLIA; NERVE CELL; NOCICEPTION; ORAL DRUG ADMINISTRATION; PAIN; PATHOPHYSIOLOGY; SPINAL CORD DORSAL HORN; TRANSGENIC MOUSE;

ADMINISTRATION, ORAL; ANEMIA, SICKLE CELL; ANIMALS; ANTIOXIDANTS; ASTROCYTES; CURCUMIN; DISEASE MODELS, ANIMAL; FEMALE; GENE EXPRESSION REGULATION; GLIAL FIBRILLARY ACIDIC PROTEIN; HUMANS; HYPERALGESIA; MICE; MICE, TRANSGENIC; MICROGLIA; NEURONS; NEUROPEPTIDES; NOCICEPTION; OXIDATIVE STRESS; PAIN; REACTIVE OXYGEN SPECIES; SPINAL CORD DORSAL HORN; UBIQUINONE;

EID: 84957699118     PISSN: 03906078     EISSN: 15928721     Source Type: Journal    
DOI: 10.3324/haematol.2015.137489     Document Type: Letter

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