메뉴 건너뛰기




Volumn 30, Issue 7, 2016, Pages 1015-1025

Maraviroc and reverse transcriptase inhibitors combinations as potential preexposure prophylaxis candidates

Author keywords

antiretrovirals; combination; explant; mucosal; prevention

Indexed keywords

DAPIVIRINE; MARAVIROC; N [4 CHLORO 3 (3 METHYL 2 BUTENYLOXY)PHENYL] 2 METHYL 3 FURANCARBOTHIOAMIDE; PLACEBO; TENOFOVIR; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; CYCLOHEXANE DERIVATIVE; RNA DIRECTED DNA POLYMERASE INHIBITOR; TRIAZOLE DERIVATIVE;

EID: 84957675230     PISSN: 02699370     EISSN: 14735571     Source Type: Journal    
DOI: 10.1097/QAD.0000000000001043     Document Type: Article
Times cited : (18)

References (50)
  • 1
    • 0037196929 scopus 로고    scopus 로고
    • Systematic review and meta-analysis of evidence for increasing numbers of drugs in antiretroviral combination therapy
    • Jordan R, Gold L, Cummins C, Hyde C. Systematic review and meta-analysis of evidence for increasing numbers of drugs in antiretroviral combination therapy. BMJ 2002; 324:757.
    • (2002) BMJ , vol.324 , pp. 757
    • Jordan, R.1    Gold, L.2    Cummins, C.3    Hyde, C.4
  • 2
    • 84881262655 scopus 로고    scopus 로고
    • HIV drug resistance: Problems and perspectives
    • Pennings PS. HIV drug resistance: problems and perspectives. Infect Dis Rep 2013; 5:e5.
    • (2013) Infect Dis Rep , vol.5 , pp. e5
    • Pennings, P.S.1
  • 3
    • 84905485577 scopus 로고    scopus 로고
    • Burden of nonnucleoside reverse transcriptase inhibitor resistance in HIV-1-infected patients: A systematic review and meta-analysis
    • Snedecor SJ, Sudharshan L, Nedrow K, Bhanegaonkar A, Simpson KN, Haider S, et al. Burden of nonnucleoside reverse transcriptase inhibitor resistance in HIV-1-infected patients: a systematic review and meta-analysis. AIDS Res Hum Retro-viruses 2014; 30:753-768.
    • (2014) AIDS Res Hum Retro-viruses , vol.30 , pp. 753-768
    • Snedecor, S.J.1    Sudharshan, L.2    Nedrow, K.3    Bhanegaonkar, A.4    Simpson, K.N.5    Haider, S.6
  • 4
    • 0036787140 scopus 로고    scopus 로고
    • HIV transmission risk behaviours among HIV-positive persons in serodiscordant relationships
    • Kalichman SC, Rompa D, Luke W, Austin J. HIV transmission risk behaviours among HIV-positive persons in serodiscordant relationships. Int J STD AIDS 2002; 13:677-682.
    • (2002) Int J STD AIDS , vol.13 , pp. 677-682
    • Kalichman, S.C.1    Rompa, D.2    Luke, W.3    Austin, J.4
  • 5
    • 0032127568 scopus 로고    scopus 로고
    • Heterosexual transmission of human immunodeficiency virus: Variability of infectiv-ity throughout the course of infection. European Study Group on Heterosexual Transmission of HIV
    • Leynaert B, Downs AM, de Vincenzi I. Heterosexual transmission of human immunodeficiency virus: variability of infectiv-ity throughout the course of infection. European Study Group on Heterosexual Transmission of HIV. Am J Epidemiol 1998; 148:88-96.
    • (1998) Am J Epidemiol , vol.148 , pp. 88-96
    • Leynaert, B.1    Downs, A.M.2    De Vincenzi, I.3
  • 6
    • 0030609749 scopus 로고    scopus 로고
    • Heterosexual transmission of human immunodeficiency virus (HIV) in northern California: Results from a ten-year study
    • Padian NS, Shiboski SC, Glass SO, Vittinghoff E. Heterosexual transmission of human immunodeficiency virus (HIV) in northern California: results from a ten-year study. Am J Epidemiol 1997; 146:350-357.
    • (1997) Am J Epidemiol , vol.146 , pp. 350-357
    • Padian, N.S.1    Shiboski, S.C.2    Glass, S.O.3    Vittinghoff, E.4
  • 8
    • 0033827042 scopus 로고    scopus 로고
    • Enhanced levels of functional HIV-1 co-receptors on human mucosal T cells demonstrated using intestinal biopsy tissue
    • Anton PA, Elliott J, Poles MA, McGowan IM, Matud J, Hultin LE, et al. Enhanced levels of functional HIV-1 co-receptors on human mucosal T cells demonstrated using intestinal biopsy tissue. Aids 2000; 14:1761-1765.
    • (2000) AIDS , vol.14 , pp. 1761-1765
    • Anton, P.A.1    Elliott, J.2    Poles, M.A.3    McGowan, I.M.4    Matud, J.5    Hultin, L.E.6
  • 9
    • 0032947858 scopus 로고    scopus 로고
    • Human intestinal lamina propria lymphocytes are naturally permissive to HIV-1 infection
    • Lapenta C, Boirivant M, Marini M, Santini SM, Logozzi M, Viora M, et al. Human intestinal lamina propria lymphocytes are naturally permissive to HIV-1 infection. Eur J Immunol 1999; 29:1202-1208.
    • (1999) Eur J Immunol , vol.29 , pp. 1202-1208
    • Lapenta, C.1    Boirivant, M.2    Marini, M.3    Santini, S.M.4    Logozzi, M.5    Viora, M.6
  • 10
    • 0034888099 scopus 로고    scopus 로고
    • A preponderance of CCR5(R) CXCR4(R) mononuclear cells enhances gastrointestinal mucosal susceptibility to human immunodeficiency virus type 1 infection
    • Poles MA, Elliott J, Taing P, Anton PA, Chen IS. A preponderance of CCR5(R) CXCR4(R) mononuclear cells enhances gastrointestinal mucosal susceptibility to human immunodeficiency virus type 1 infection. J Virol 2001; 75:8390-8399.
    • (2001) J Virol , vol.75 , pp. 8390-8399
    • Poles, M.A.1    Elliott, J.2    Taing, P.3    Anton, P.A.4    Chen, I.S.5
  • 11
  • 12
    • 84875746052 scopus 로고    scopus 로고
    • A phase 1 randomized, double blind, placebo controlled rectal safety and acceptability study of tenofovir 1% gel (MTN-007)
    • McGowan I, Hoesley C, Cranston RD, Andrew P, Janocko L, Dai JY, et al. A phase 1 randomized, double blind, placebo controlled rectal safety and acceptability study of tenofovir 1% gel (MTN-007). PLoS One 2013; 8:e60147.
    • (2013) PLoS One , vol.8 , pp. e60147
    • McGowan, I.1    Hoesley, C.2    Cranston, R.D.3    Andrew, P.4    Janocko, L.5    Dai, J.Y.6
  • 13
    • 84868474359 scopus 로고    scopus 로고
    • RMP-02/MTN-006: A phase 1 placebo-controlled trial of rectally applied 1% vaginal TFV gel with comparison to oral TDF
    • Anton P, Cranston R, Carballo-Dieguez A, Kashuba A, Khanu-khova E, Elliott J, et al. RMP-02/MTN-006: a phase 1 placebo-controlled trial of rectally applied 1% vaginal TFV gel with comparison to oral TDF. AIDS Res Hum Retroviruses 2012; 28:1412-1421.
    • (2012) AIDS Res Hum Retroviruses , vol.28 , pp. 1412-1421
    • Anton, P.1    Cranston, R.2    Carballo-Dieguez, A.3    Kashuba, A.4    Khanu-Khova, E.5    Elliott, J.6
  • 15
    • 80053248640 scopus 로고    scopus 로고
    • First phase 1 double-blind, placebo-controlled, randomized rectal microbicide trial using UC781 gel with a novel index of ex vivo efficacy
    • Anton PA, Saunders T, Elliott J, Khanukhova E, Dennis R, Adler A, et al. First phase 1 double-blind, placebo-controlled, randomized rectal microbicide trial using UC781 gel with a novel index of ex vivo efficacy. PLoS One 2011; 6:e23243.
    • (2011) PLoS One , vol.6 , pp. e23243
    • Anton, P.A.1    Saunders, T.2    Elliott, J.3    Khanukhova, E.4    Dennis, R.5    Adler, A.6
  • 16
    • 84890599203 scopus 로고    scopus 로고
    • The development of rectal microbicides for HIV prevention
    • McGowan I. The development of rectal microbicides for HIV prevention. Expert Opin Drug Deliv 2014; 11:69-82.
    • (2014) Expert Opin Drug Deliv , vol.11 , pp. 69-82
    • McGowan, I.1
  • 17
    • 79251508013 scopus 로고    scopus 로고
    • Selective transmission of R5 HIV-1 variants: Where is the gatekeeper?
    • Grivel JC, Shattock RJ, Margolis LB. Selective transmission of R5 HIV-1 variants: where is the gatekeeper? J Transl Med 2011; 9 (Suppl 1):S6.
    • (2011) J Transl Med , vol.9 , pp. S6
    • Grivel, J.C.1    Shattock, R.J.2    Margolis, L.B.3
  • 18
    • 66049139947 scopus 로고    scopus 로고
    • Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection
    • Salazar-Gonzalez JF, Salazar MG, Keele BF, Learn GH, Giorgi EE, Li H, et al. Genetic identity, biological phenotype, and evolutionary pathways of transmitted/founder viruses in acute and early HIV-1 infection. J Exp Med 2009; 206:1273-1289.
    • (2009) J Exp Med , vol.206 , pp. 1273-1289
    • Salazar-Gonzalez, J.F.1    Salazar, M.G.2    Keele, B.F.3    Learn, G.H.4    Giorgi, E.E.5    Li, H.6
  • 20
    • 81255157679 scopus 로고    scopus 로고
    • Nonaqueous silicone elastomer gels as a vaginal micro-bicide delivery system for the HIV-1 entry inhibitor maraviroc
    • Forbes CJ, Lowry D, Geer L, Veazey RS, Shattock RJ, Klasse PJ, et al. Nonaqueous silicone elastomer gels as a vaginal micro-bicide delivery system for the HIV-1 entry inhibitor maraviroc. J Control Release 2011; 156:161-169.
    • (2011) J Control Release , vol.156 , pp. 161-169
    • Forbes, C.J.1    Lowry, D.2    Geer, L.3    Veazey, R.S.4    Shattock, R.J.5    Klasse, P.J.6
  • 22
    • 77955673220 scopus 로고    scopus 로고
    • Protection of rhesus macaques from vaginal infection by vaginally delivered maraviroc, an inhibitor of HIV-1 entry via the CCR5 co-receptor
    • Veazey RS, Ketas TJ, Dufour J, Moroney-Rasmussen T, Green LC, Klasse PJ, Moore JP. Protection of rhesus macaques from vaginal infection by vaginally delivered maraviroc, an inhibitor of HIV-1 entry via the CCR5 co-receptor. J Infect Dis 2010; 202:739-744.
    • (2010) J Infect Dis , vol.202 , pp. 739-744
    • Veazey, R.S.1    Ketas, T.J.2    Dufour, J.3    Moroney-Rasmussen, T.4    Green, L.C.5    Klasse, P.J.6    Moore, J.P.7
  • 25
    • 0026726809 scopus 로고
    • Complete nucleotide sequence, genome organization, and biological properties of human immunodeficiency virus type 1 in vivo: Evidence for limited defectiveness and complementation
    • Li Y, Hui H, Burgess CJ, Price RW, Sharp PM, Hahn BH, Shaw GM. Complete nucleotide sequence, genome organization, and biological properties of human immunodeficiency virus type 1 in vivo: evidence for limited defectiveness and complementation. J Virol 1992; 66:6587-6600.
    • (1992) J Virol , vol.66 , pp. 6587-6600
    • Li, Y.1    Hui, H.2    Burgess, C.J.3    Price, R.W.4    Sharp, P.M.5    Hahn, B.H.6    Shaw, G.M.7
  • 26
    • 0025815375 scopus 로고
    • Molecular characterization of human immunodeficiency virus type 1 cloned directly from uncultured human brain tissue: Identification of replication-competent and-defective viral genomes
    • Li Y, Kappes JC, Conway JA, Price RW, Shaw GM, Hahn BH. Molecular characterization of human immunodeficiency virus type 1 cloned directly from uncultured human brain tissue: identification of replication-competent and-defective viral genomes. J Virol 1991; 65:3973-3985.
    • (1991) J Virol , vol.65 , pp. 3973-3985
    • Li, Y.1    Kappes, J.C.2    Conway, J.A.3    Price, R.W.4    Shaw, G.M.5    Hahn, B.H.6
  • 28
    • 84934925969 scopus 로고    scopus 로고
    • A single-residue change in the HIV-1 V3 loop associated with maraviroc resistance impairs CCR5 binding affinity while increasing replicative capacity
    • Garcia-Perez J, Staropoli I, Azoulay S, Heinrich JT, Cascajero A, Colin P, et al. A single-residue change in the HIV-1 V3 loop associated with maraviroc resistance impairs CCR5 binding affinity while increasing replicative capacity. Retrovirology 2015; 12:50.
    • (2015) Retrovirology , vol.12 , pp. 50
    • Garcia-Perez, J.1    Staropoli, I.2    Azoulay, S.3    Heinrich, J.T.4    Cascajero, A.5    Colin, P.6
  • 30
    • 84878904611 scopus 로고    scopus 로고
    • The magnitude of HIV-1 resistance to the CCR5 antagonist maraviroc may impart a differential alteration in HIV-1 tropism for macrophages and T-cell subsets
    • Flynn JK, Paukovics G, Moore MS, Ellett A, Gray LR, Duncan R, et al. The magnitude of HIV-1 resistance to the CCR5 antagonist maraviroc may impart a differential alteration in HIV-1 tropism for macrophages and T-cell subsets. Virology 2013; 442:51-58.
    • (2013) Virology , vol.442 , pp. 51-58
    • Flynn, J.K.1    Paukovics, G.2    Moore, M.S.3    Ellett, A.4    Gray, L.R.5    Duncan, R.6
  • 31
    • 84876992931 scopus 로고    scopus 로고
    • A common mechanism of clinical HIV-1 resistance to the CCR5 antagonist maraviroc despite divergent resistance levels and lack of common gp120 resistance mutations
    • Roche M, Salimi H, Duncan R, Wilkinson BL, Chikere K, Moore MS, et al. A common mechanism of clinical HIV-1 resistance to the CCR5 antagonist maraviroc despite divergent resistance levels and lack of common gp120 resistance mutations. Retro-virology 2013; 10:43.
    • (2013) Retro-virology , vol.10 , pp. 43
    • Roche, M.1    Salimi, H.2    Duncan, R.3    Wilkinson, B.L.4    Chikere, K.5    Moore, M.S.6
  • 32
    • 0033856458 scopus 로고    scopus 로고
    • Sensitivity of human immunodeficiency virus type 1 to the fusion inhibitor T-20 is modulated by coreceptor specificity defined by the V3 loop of gp120
    • Derdeyn CA, Decker JM, Sfakianos JN, Wu X, O'Brien WA, Ratner L, et al. Sensitivity of human immunodeficiency virus type 1 to the fusion inhibitor T-20 is modulated by coreceptor specificity defined by the V3 loop of gp120. J Virol 2000; 74:8358-8367.
    • (2000) J Virol , vol.74 , pp. 8358-8367
    • Derdeyn, C.A.1    Decker, J.M.2    Sfakianos, J.N.3    Wu, X.4    O'Brien, W.A.5    Ratner, L.6
  • 33
    • 0031954686 scopus 로고    scopus 로고
    • Effects of CCR5 and CD4 cell surface concentrations on infections by macrophagetropic isolates of human immunodeficiency virus type 1
    • Platt EJ, Wehrly K, Kuhmann SE, Chesebro B, Kabat D. Effects of CCR5 and CD4 cell surface concentrations on infections by macrophagetropic isolates of human immunodeficiency virus type 1. J Virol 1998; 72:2855-2864.
    • (1998) J Virol , vol.72 , pp. 2855-2864
    • Platt, E.J.1    Wehrly, K.2    Kuhmann, S.E.3    Chesebro, B.4    Kabat, D.5
  • 34
    • 0036090585 scopus 로고    scopus 로고
    • Emergence of resistant human immunodeficiency virus type 1 in patients receiving fusion inhibitor (T-20) monotherapy
    • Wei X, Decker JM, Liu H, Zhang Z, Arani RB, Kilby JM, et al. Emergence of resistant human immunodeficiency virus type 1 in patients receiving fusion inhibitor (T-20) monotherapy. Antimicrob Agents Chemother 2002; 46:1896-1905.
    • (2002) Antimicrob Agents Chemother , vol.46 , pp. 1896-1905
    • Wei, X.1    Decker, J.M.2    Liu, H.3    Zhang, Z.4    Arani, R.B.5    Kilby, J.M.6
  • 35
    • 0029063578 scopus 로고
    • Growth of macrophage-tropic and primary human immunodeficiency virus type 1 (HIV-1) isolates in a unique CD4R T-cell clone (PM1): Failure to downregulate CD4 and to interfere with cell-line-tropic HIV-1
    • Lusso P, Cocchi F, Balotta C, Markham PD, Louie A, Farci P, et al. Growth of macrophage-tropic and primary human immunodeficiency virus type 1 (HIV-1) isolates in a unique CD4R T-cell clone (PM1): failure to downregulate CD4 and to interfere with cell-line-tropic HIV-1. J Virol 1995; 69:3712-3720.
    • (1995) J Virol , vol.69 , pp. 3712-3720
    • Lusso, P.1    Cocchi, F.2    Balotta, C.3    Markham, P.D.4    Louie, A.5    Farci, P.6
  • 36
    • 0032889517 scopus 로고    scopus 로고
    • Enhancement of human immunodeficiency virus type 1 infection by the CC-chemokine RANTES is independent of the mechanism of virus-cell fusion
    • Gordon CJ, Muesing MA, Proudfoot AE, Power CA, Moore JP, Trkola A. Enhancement of human immunodeficiency virus type 1 infection by the CC-chemokine RANTES is independent of the mechanism of virus-cell fusion. J Virol 1999; 73:684-694.
    • (1999) J Virol , vol.73 , pp. 684-694
    • Gordon, C.J.1    Muesing, M.A.2    Proudfoot, A.E.3    Power, C.A.4    Moore, J.P.5    Trkola, A.6
  • 38
    • 20644433322 scopus 로고    scopus 로고
    • The impact of envelope glycoprotein cleavage on the antigenicity, infectivity, and neutralization sensitivity of Env-pseudotyped human immunodeficiency virus type 1 particles
    • Herrera C, Klasse PJ, Michael E, Kake S, Barnes K, Kibler CW, et al. The impact of envelope glycoprotein cleavage on the antigenicity, infectivity, and neutralization sensitivity of Env-pseudotyped human immunodeficiency virus type 1 particles. Virology 2005; 338:154-172.
    • (2005) Virology , vol.338 , pp. 154-172
    • Herrera, C.1    Klasse, P.J.2    Michael, E.3    Kake, S.4    Barnes, K.5    Kibler, C.W.6
  • 40
    • 84874736997 scopus 로고    scopus 로고
    • Transmitted/founder and chronic HIV-1 envelope proteins are distinguished by differential utilization of CCR5
    • Parker ZF, Iyer SS, Wilen CB, Parrish NF, Chikere KC, Lee FH, et al. Transmitted/founder and chronic HIV-1 envelope proteins are distinguished by differential utilization of CCR5. J Virol 2013; 87:2401-2411.
    • (2013) J Virol , vol.87 , pp. 2401-2411
    • Parker, Z.F.1    Iyer, S.S.2    Wilen, C.B.3    Parrish, N.F.4    Chikere, K.C.5    Lee, F.H.6
  • 41
    • 84878528694 scopus 로고    scopus 로고
    • Comparison of viral Env proteins from acute and chronic infections of subtype C human immunodeficiency virus type 1 identifies differences in glycosy-lation and CCR5 utilization and suggests a new strategy for immunogen design
    • Ping LH, Joseph SB, Anderson JA, Abrahams MR, Salazar-Gonzalez JF, Kincer LP, et al. Comparison of viral Env proteins from acute and chronic infections of subtype C human immunodeficiency virus type 1 identifies differences in glycosy-lation and CCR5 utilization and suggests a new strategy for immunogen design. J Virol 2013; 87:7218-7233.
    • (2013) J Virol , vol.87 , pp. 7218-7233
    • Ping, L.H.1    Joseph, S.B.2    Anderson, J.A.3    Abrahams, M.R.4    Salazar-Gonzalez, J.F.5    Kincer, L.P.6
  • 42
    • 79551578453 scopus 로고    scopus 로고
    • Early events in sexual transmission of HIV and SIV and opportunities for interventions
    • Haase AT. Early events in sexual transmission of HIV and SIV and opportunities for interventions. Annu Rev Med 2011; 62:127-139.
    • (2011) Annu Rev Med , vol.62 , pp. 127-139
    • Haase, A.T.1
  • 45
    • 80055005719 scopus 로고    scopus 로고
    • Colorectal microbicide design: Triple combinations of reverse transcriptase inhibitors are optimal against HIV-1 in tissue explants
    • Herrera C, Cranage M, McGowan I, Anton P, Shattock RJ. Colorectal microbicide design: triple combinations of reverse transcriptase inhibitors are optimal against HIV-1 in tissue explants. Aids 2011; 25:1971-1979.
    • (2011) AIDS , vol.25 , pp. 1971-1979
    • Herrera, C.1    Cranage, M.2    McGowan, I.3    Anton, P.4    Shattock, R.J.5
  • 46
    • 27644510382 scopus 로고    scopus 로고
    • Maraviroc(UK-427;857), apotent, orallybioavailable, andselec-tive small-molecule inhibitor of chemokine receptor CCR5 with broad-spectrum antihuman immunodeficiency virus type 1 activity
    • Dorr P, Westby M, Dobbs S, Griffin P, Irvine B, Macartney M, et al. Maraviroc(UK-427;857), apotent, orallybioavailable, andselec-tive small-molecule inhibitor of chemokine receptor CCR5 with broad-spectrum antihuman immunodeficiency virus type 1 activity. Antimicrob Agents Chemother 2005; 49:4721-4732.
    • (2005) Antimicrob Agents Chemother , vol.49 , pp. 4721-4732
    • Dorr, P.1    Westby, M.2    Dobbs, S.3    Griffin, P.4    Irvine, B.5    Macartney, M.6
  • 47
    • 43249120426 scopus 로고    scopus 로고
    • Recent advancesin the characterization of HIV-1 neutralization assays for standardized evaluation of the antibody response to infection and vaccination
    • Polonis VR, Brown BK, Rosa Borges A, Zolla-Pazner S, Dimitrov DS, Zhang MY, et al. Recent advancesin the characterization of HIV-1 neutralization assays for standardized evaluation of the antibody response to infection and vaccination. Virology 2008; 375:315-320.
    • (2008) Virology , vol.375 , pp. 315-320
    • Polonis, V.R.1    Brown, B.K.2    Rosa Borges, A.3    Zolla-Pazner, S.4    Dimitrov, D.S.5    Zhang, M.Y.6
  • 48
    • 0017706693 scopus 로고
    • A simple generalized equation for the analysis of multiple inhibitions of Michaelis-menten kinetic systems
    • Chou T-C, Talalay P. A simple generalized equation for the analysis of multiple inhibitions of Michaelis-menten kinetic systems. J Biol Chem 1977; 252:6438-6442.
    • (1977) J Biol Chem , vol.252 , pp. 6438-6442
    • Chou, T.-C.1    Talalay, P.2
  • 49
    • 4243335032 scopus 로고
    • Computerized simulation of dose reduction index (DRI) in synergistic drug combinations
    • Chou J, Chou T-C. Computerized simulation of dose reduction index (DRI) in synergistic drug combinations. Pharmacologist 1988; 30:231.
    • (1988) Pharmacologist , vol.30 , pp. 231
    • Chou, J.1    Chou, T.-C.2
  • 50
    • 84875010204 scopus 로고    scopus 로고
    • Molecular basis of human imunodeficiency virus type 1 drug resistance: Overview and recent developments
    • Menéndez-Arias L. Molecular basis of human imunodeficiency virus type 1 drug resistance: overview and recent developments. Antiviral Res 2013; 98:93-120.
    • (2013) Antiviral Res , vol.98 , pp. 93-120
    • Menéndez-Arias, L.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.