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Volumn 6, Issue , 2016, Pages

One-step generation of triple gene-targeted pigs using CRISPR/Cas9 system

Author keywords

[No Author keywords available]

Indexed keywords

PARKIN; PROTEIN DEGLYCASE DJ-1; PROTEIN KINASE; PTEN-INDUCED PUTATIVE KINASE; UBIQUITIN PROTEIN LIGASE;

EID: 84957592496     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep20620     Document Type: Article
Times cited : (104)

References (24)
  • 1
    • 63149090431 scopus 로고    scopus 로고
    • Parkinson's disease: From monogenic forms to genetic susceptibility factors
    • Lesage, S. & Brice, A. Parkinson's disease: from monogenic forms to genetic susceptibility factors. Hum Mol Genet 18, R48-59 (2009).
    • (2009) Hum Mol Genet , vol.18 , pp. R48-R59
    • Lesage, S.1    Brice, A.2
  • 2
    • 0036151884 scopus 로고    scopus 로고
    • Localization of autosomal recessive early-onset parkinsonism to chromosome 1p36 (PARK7) in an independent dataset
    • Bonifati, V. et al. Localization of autosomal recessive early-onset parkinsonism to chromosome 1p36 (PARK7) in an independent dataset. Annals of neurology 51, 253-256 (2002).
    • (2002) Annals of Neurology , vol.51 , pp. 253-256
    • Bonifati, V.1
  • 3
    • 0032499264 scopus 로고    scopus 로고
    • Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
    • Kitada, T. et al. Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature 392, 605-608 (1998).
    • (1998) Nature , vol.392 , pp. 605-608
    • Kitada, T.1
  • 4
    • 2442668926 scopus 로고    scopus 로고
    • Hereditary early-onset Parkinson's disease caused by mutations in PINK1
    • Valente, E. M. et al. Hereditary early-onset Parkinson's disease caused by mutations in PINK1. Science 304, 1158-1160 (2004).
    • (2004) Science , vol.304 , pp. 1158-1160
    • Valente, E.M.1
  • 5
    • 0141891953 scopus 로고    scopus 로고
    • Parkin-deficient mice exhibit nigrostriatal deficits but not loss of dopaminergic neurons
    • Goldberg, M. S. et al. Parkin-deficient mice exhibit nigrostriatal deficits but not loss of dopaminergic neurons. J Biol Chem 278, 43628-43635 (2003).
    • (2003) J Biol Chem , vol.278 , pp. 43628-43635
    • Goldberg, M.S.1
  • 6
    • 70349923087 scopus 로고    scopus 로고
    • Absence of nigral degeneration in aged parkin/DJ-1/PINK1 triple knockout mice
    • Kitada, T., Tong, Y., Gautier, C. A. & Shen, J. Absence of nigral degeneration in aged parkin/DJ-1/PINK1 triple knockout mice. J Neurochem 111, 696-702 (2009).
    • (2009) J Neurochem , vol.111 , pp. 696-702
    • Kitada, T.1    Tong, Y.2    Gautier, C.A.3    Shen, J.4
  • 7
    • 84898033899 scopus 로고    scopus 로고
    • Species-dependent neuropathology in transgenic SOD1 pigs
    • Yang, H. Q. et al. Species-dependent neuropathology in transgenic SOD1 pigs. Cell Res 24, 464-481 (2014).
    • (2014) Cell Res , vol.24 , pp. 464-481
    • Yang, H.Q.1
  • 8
    • 84885468845 scopus 로고    scopus 로고
    • A transgenic minipig model of Huntington's Disease
    • Baxa, M. et al. A transgenic minipig model of Huntington's Disease. J Huntington's Dis 2, 47-68 (2013).
    • (2013) J Huntington's Dis , vol.2 , pp. 47-68
    • Baxa, M.1
  • 9
    • 84897594300 scopus 로고    scopus 로고
    • One-step generation of knockout pigs by zygote injection of CRISPR/Cas system
    • Hai, T., Teng, F., Guo, R., Li, W. & Zhou, Q. One-step generation of knockout pigs by zygote injection of CRISPR/Cas system. Cell Res 24, 372-375 (2014).
    • (2014) Cell Res , vol.24 , pp. 372-375
    • Hai, T.1    Teng, F.2    Guo, R.3    Li, W.4    Zhou, Q.5
  • 10
    • 84921602939 scopus 로고    scopus 로고
    • Use of the CRISPR/Cas9 System to Produce Genetically Engineered Pigs from In Vitro-Derived Oocytes and Embryos
    • Whitworth, K. M. et al. Use of the CRISPR/Cas9 System to Produce Genetically Engineered Pigs from In Vitro-Derived Oocytes and Embryos. Biol Reprod 91, 78 (2014).
    • (2014) Biol Reprod , vol.91 , pp. 78
    • Whitworth, K.M.1
  • 11
    • 84938537178 scopus 로고    scopus 로고
    • CRISPR/Cas9: A powerful genetic engineering tool for establishing large animal models of neurodegenerative diseases
    • Tu, Z., Yang, W., Yan, S., Guo, X. & Li, X. J. CRISPR/Cas9: a powerful genetic engineering tool for establishing large animal models of neurodegenerative diseases. Mol Neurodegener 10, 35 (2015).
    • (2015) Mol Neurodegener , vol.10 , pp. 35
    • Tu, Z.1    Yang, W.2    Yan, S.3    Guo, X.4    Li, X.J.5
  • 12
    • 52649172321 scopus 로고    scopus 로고
    • Familial parkinsonism with digenic Parkin and PINK1 mutations
    • Funayama, M. et al. Familial parkinsonism with digenic Parkin and PINK1 mutations. Movement Disord 23, 1461-1465 (2008).
    • (2008) Movement Disord , vol.23 , pp. 1461-1465
    • Funayama, M.1
  • 13
    • 84883779087 scopus 로고    scopus 로고
    • Simultaneous generation and germline transmission of multiple gene mutations in rat using CRISPR-Cas systems
    • Li, W., Teng, F., Li, T. & Zhou, Q. Simultaneous generation and germline transmission of multiple gene mutations in rat using CRISPR-Cas systems. Nature Biotechnol 31, 684-686 (2013).
    • (2013) Nature Biotechnol , vol.31 , pp. 684-686
    • Li, W.1    Teng, F.2    Li, T.3    Zhou, Q.4
  • 14
    • 84897530474 scopus 로고    scopus 로고
    • Dual sgRNAs facilitate CRISPR/Cas9-mediated mouse genome targeting
    • Zhou, J. K. et al. Dual sgRNAs facilitate CRISPR/Cas9-mediated mouse genome targeting. FEBS J 281, 1717-1725 (2014).
    • (2014) FEBS J , vol.281 , pp. 1717-1725
    • Zhou, J.K.1
  • 15
    • 84865070369 scopus 로고    scopus 로고
    • A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity
    • Jinek, M. et al. A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity. Science 337, 816-821 (2012).
    • (2012) Science , vol.337 , pp. 816-821
    • Jinek, M.1
  • 16
    • 84930503842 scopus 로고    scopus 로고
    • Advances in CRISPR-Cas9 genome engineering: Lessons learned from RNA interference
    • Barrangou, R. et al. Advances in CRISPR-Cas9 genome engineering: lessons learned from RNA interference. Nucleic Acids Res 43, 3407-3419 (2015).
    • (2015) Nucleic Acids Res , vol.43 , pp. 3407-3419
    • Barrangou, R.1
  • 17
    • 55849122639 scopus 로고    scopus 로고
    • Mitochondrial biology and oxidative stress in Parkinson disease pathogenesis
    • Henchcliffe, C. & Beal, M. F. Mitochondrial biology and oxidative stress in Parkinson disease pathogenesis. Nat Clin Prac Neuro 4, 600-609 (2008).
    • (2008) Nat Clin Prac Neuro , vol.4 , pp. 600-609
    • Henchcliffe, C.1    Beal, M.F.2
  • 18
    • 84880570576 scopus 로고    scopus 로고
    • High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells
    • Fu, Y. et al. High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells. Nature Biotechnol 31, 822-826 (2013).
    • (2013) Nature Biotechnol , vol.31 , pp. 822-826
    • Fu, Y.1
  • 19
    • 84923112396 scopus 로고    scopus 로고
    • Novel variation and de novo mutation rates in population-wide de novo assembled Danish trios
    • Besenbacher, S. et al. Novel variation and de novo mutation rates in population-wide de novo assembled Danish trios. Nature Commun 6, 5969 (2015).
    • (2015) Nature Commun , vol.6 , pp. 5969
    • Besenbacher, S.1
  • 20
    • 84898889321 scopus 로고    scopus 로고
    • CasOT: A genome-wide Cas9/gRNA off-target searching tool
    • Xiao, A. et al. CasOT: a genome-wide Cas9/gRNA off-target searching tool. Bioinformatics 30, 1180-1182 (2014).
    • (2014) Bioinformatics , vol.30 , pp. 1180-1182
    • Xiao, A.1
  • 21
    • 84930153818 scopus 로고    scopus 로고
    • Off-target mutations are rare in Cas9-modified mice
    • Iyer, V. et al. Off-target mutations are rare in Cas9-modified mice. Nat Methods 12, 479 (2015).
    • (2015) Nat Methods , vol.12 , pp. 479
    • Iyer, V.1
  • 22
    • 84923241422 scopus 로고    scopus 로고
    • Dual sgRNA-directed gene knockout using CRISPR/Cas9 technology in Caenorhabditis elegans
    • Chen, X. et al. Dual sgRNA-directed gene knockout using CRISPR/Cas9 technology in Caenorhabditis elegans. Sci Rep 4, 7581 (2014).
    • (2014) Sci Rep , vol.4 , pp. 7581
    • Chen, X.1
  • 23
    • 84940107277 scopus 로고    scopus 로고
    • Dual gRNAs guided CRISPR/Cas9 system inhibits hepatitis B virus replication
    • Wang, J. et al. Dual gRNAs guided CRISPR/Cas9 system inhibits hepatitis B virus replication. World J Gastroentero 21, 9554-9565 (2015).
    • (2015) World J Gastroentero , vol.21 , pp. 9554-9565
    • Wang, J.1
  • 24
    • 84939815032 scopus 로고    scopus 로고
    • Efficient CRISPR/Cas9-mediated biallelic gene disruption and site-specific knockin after rapid selection of highly active sgRNAs in pigs
    • Wang, X. et al. Efficient CRISPR/Cas9-mediated biallelic gene disruption and site-specific knockin after rapid selection of highly active sgRNAs in pigs. Sci Rep 5, 13348 (2015).
    • (2015) Sci Rep , vol.5
    • Wang, X.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.