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Volumn 180, Issue , 2016, Pages 131-139

Anti-diabetic effect of Xylopia aethiopica (Dunal) A. Rich. (Annonaceae) fruit acetone fraction in a type 2 diabetes model of rats

Author keywords

Acetone fraction; Fruit ethnolic extract; Rats; Type 2 diabetes; Xylopia aethiopica

Indexed keywords

ACETONE; CREATINE KINASE MB; FRUCTOSAMINE; GLUCOSE; GLYCOGEN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; LACTATE DEHYDROGENASE; LOW DENSITY LIPOPROTEIN CHOLESTEROL; METFORMIN; ORAL ANTIDIABETIC AGENT; PLANT EXTRACT; UNCLASSIFIED DRUG; XYLOPIA AETHIOPICA EXTRACT; ANTIDIABETIC AGENT; GLUCOSE BLOOD LEVEL; LIPID; SOLVENT;

EID: 84957580355     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2016.01.009     Document Type: Article
Times cited : (43)

References (53)
  • 1
    • 84865982686 scopus 로고    scopus 로고
    • Effect of diets supplemented with Ethiopian pepper [Xylopia aethiopica (Dun.) A. Rich (Annonaceae)] and Ashanti pepper [Piper guineense Schumach. et Thonn (Piperaceae)] on some biochemical parameters in normal rats
    • S.A. Adefegha, and G. Oboh Effect of diets supplemented with Ethiopian pepper [Xylopia aethiopica (Dun.) A. Rich (Annonaceae)] and Ashanti pepper [Piper guineense Schumach. et Thonn (Piperaceae)] on some biochemical parameters in normal rats Asian Pac. J. Trop. Biomed. 2 2012 S558 S566
    • (2012) Asian Pac. J. Trop. Biomed. , vol.2 , pp. S558-S566
    • Adefegha, S.A.1    Oboh, G.2
  • 2
    • 84862003630 scopus 로고    scopus 로고
    • Inhibition of key enzymes linked to type 2 diabetes and sodium nitroprusside-induced lipid peroxidation in rat pancreas by water extractable phytochemicals from some tropical species
    • S.A. Adefegha, and G. Oboh Inhibition of key enzymes linked to type 2 diabetes and sodium nitroprusside-induced lipid peroxidation in rat pancreas by water extractable phytochemicals from some tropical species Pharm. Biol. 50 2012 857 865
    • (2012) Pharm. Biol. , vol.50 , pp. 857-865
    • Adefegha, S.A.1    Oboh, G.2
  • 3
    • 84894576020 scopus 로고    scopus 로고
    • 2+- induced lipid peroxidation in rat's brain-in vitro
    • 2+- induced lipid peroxidation in rat's brain-in vitro J. Food Process. Technol. 2 2011 104 10.4172/2157-7110.1000104
    • (2011) J. Food Process. Technol. , vol.2 , pp. 104
    • Adefegha, S.A.1    Oboh, G.2
  • 4
    • 84872781682 scopus 로고    scopus 로고
    • Soybean phenolic-rich extracts inhibit key-enzymes linked to type 2 diabetes (α-amylase and α-glucosidase) and hyper-tension (angiotensin i converting enzyme) in vitro
    • A.O. Ademiluyi, and G. Oboh Soybean phenolic-rich extracts inhibit key-enzymes linked to type 2 diabetes (α-amylase and α-glucosidase) and hyper-tension (angiotensin I converting enzyme) in vitro Exp. Toxicol. Pathol. 65 2013 305 309
    • (2013) Exp. Toxicol. Pathol. , vol.65 , pp. 305-309
    • Ademiluyi, A.O.1    Oboh, G.2
  • 6
    • 58149337276 scopus 로고    scopus 로고
    • Islets in type 2 diabetes: In honor of Dr. Robert C. Turner
    • S. Bonner-Weir, and T.D. O'Brien Islets in type 2 diabetes: in honor of Dr. Robert C. Turner Diabetes 57 2008 2899 2904
    • (2008) Diabetes , vol.57 , pp. 2899-2904
    • Bonner-Weir, S.1    O'Brien, T.D.2
  • 7
    • 78049440471 scopus 로고    scopus 로고
    • α-Glucosidase inhibition and the in vivo hypoglycemic effect of butyl-isobutyl-phthalate derived from the Laminaria japonica Rhizoid
    • T. Bu, M. Liu, L. Zheng, Y. Guo, and X. Lin α-Glucosidase inhibition and the in vivo hypoglycemic effect of butyl-isobutyl-phthalate derived from the Laminaria japonica Rhizoid Phytother. Res. 24 2010 1588 1591
    • (2010) Phytother. Res. , vol.24 , pp. 1588-1591
    • Bu, T.1    Liu, M.2    Zheng, L.3    Guo, Y.4    Lin, X.5
  • 8
    • 0034006856 scopus 로고    scopus 로고
    • Efficacy, safety, quality control, marketing and regulatory guidelines for herbal medicines (phytotherapeutic agents)
    • B.J. Calixto Efficacy, safety, quality control, marketing and regulatory guidelines for herbal medicines (phytotherapeutic agents) Braz. J. Med. Biol. Res. 33 2000 179 189
    • (2000) Braz. J. Med. Biol. Res. , vol.33 , pp. 179-189
    • Calixto, B.J.1
  • 11
    • 0024273689 scopus 로고
    • Glycogen synthesis from glucose and fructose in hepatocytes from diabetic rats
    • C.J. Ciudad, A. Carabaza, and J.J. Guinovart Glycogen synthesis from glucose and fructose in hepatocytes from diabetic rats Archiv. Biochem. Biophys. 267 1988 437 447
    • (1988) Archiv. Biochem. Biophys. , vol.267 , pp. 437-447
    • Ciudad, C.J.1    Carabaza, A.2    Guinovart, J.J.3
  • 12
    • 0026531801 scopus 로고
    • Evidence for increased liver glycogen in patients with noninsulin-dependent diabetes mellitus after a 3-day fast
    • J.N. Clore, E.P. Post, D.J. Bailey, J.E. Nestler, and W.G. Blackard Evidence for increased liver glycogen in patients with noninsulin-dependent diabetes mellitus after a 3-day fast J. Clin. Endocrinol. Metab. 74 1992 660 666
    • (1992) J. Clin. Endocrinol. Metab. , vol.74 , pp. 660-666
    • Clore, J.N.1    Post, E.P.2    Bailey, D.J.3    Nestler, J.E.4    Blackard, W.G.5
  • 13
    • 80053573338 scopus 로고    scopus 로고
    • Effect of treatment of high fat fed/low dose streptozotocin-diabetic rats with Ilepatril on vascular and neural complications
    • E.P. Davidson, L.J. Coppey, A. Holmes, B. Dake, and M.A. Yorek Effect of treatment of high fat fed/low dose streptozotocin-diabetic rats with Ilepatril on vascular and neural complications Eur. J. Pharmacol. 668 2011 497 506
    • (2011) Eur. J. Pharmacol. , vol.668 , pp. 497-506
    • Davidson, E.P.1    Coppey, L.J.2    Holmes, A.3    Dake, B.4    Yorek, M.A.5
  • 14
    • 77649103802 scopus 로고    scopus 로고
    • Novel biological insights emerging from genetic studies of type 2 diabetes and related metabolic traits
    • N.M. De Silva, and T.M. Frayling Novel biological insights emerging from genetic studies of type 2 diabetes and related metabolic traits Curr. Opin. Lipidol. 21 2010 44 50
    • (2010) Curr. Opin. Lipidol. , vol.21 , pp. 44-50
    • De Silva, N.M.1    Frayling, T.M.2
  • 17
    • 0011333277 scopus 로고
    • Chemistry of the constituents of Xylopia aethiopica. The structure of xylopic acid, a new diterpene acid
    • D.E.U. Ekong, and A.U. Ogan Chemistry of the constituents of Xylopia aethiopica. The structure of xylopic acid, a new diterpene acid J. Chem. Soc. 1968 311 312 10.1039/J39680000311
    • (1968) J. Chem. Soc. , pp. 311-312
    • Ekong, D.E.U.1    Ogan, A.U.2
  • 18
    • 77954517625 scopus 로고    scopus 로고
    • Phenolic content and antimicrobial potentials of Xylopia aethiopica and Myristica argentea
    • M. Esekhiagbe, M.A. Uzuazokaro, and C. Agatemor Phenolic content and antimicrobial potentials of Xylopia aethiopica and Myristica argentea Maced. J. Chem. Chem. Eng. 28 2009 159 162
    • (2009) Maced. J. Chem. Chem. Eng. , vol.28 , pp. 159-162
    • Esekhiagbe, M.1    Uzuazokaro, M.A.2    Agatemor, C.3
  • 19
    • 81255139770 scopus 로고    scopus 로고
    • Anti-amylase, anti-lipase and antioxidant effects of aqueous extracts of some Cameroonian spices
    • C.B. Etoundi, D. Kuaté, J.L. Ngondi, and J. Oben Anti-amylase, anti-lipase and antioxidant effects of aqueous extracts of some Cameroonian spices J. Nat. Prod. 3 2010 165 171
    • (2010) J. Nat. Prod. , vol.3 , pp. 165-171
    • Etoundi, C.B.1    Kuaté, D.2    Ngondi, J.L.3    Oben, J.4
  • 20
    • 84897927475 scopus 로고    scopus 로고
    • Effects of extracts of Hypodaphnis zenkeri and Xylopia aethiopica on blood lipids, glycemia and body weight of Triton WR-1339 and insulin resistant rats
    • C.B.O. Etoundi, D. Kuaté, J.L. Ngondi, and J.E. Oben Effects of extracts of Hypodaphnis zenkeri and Xylopia aethiopica on blood lipids, glycemia and body weight of Triton WR-1339 and insulin resistant rats Int. J. Res. Ayurveda Pharmacol. 4 2013 736 741
    • (2013) Int. J. Res. Ayurveda Pharmacol. , vol.4 , pp. 736-741
    • Etoundi, C.B.O.1    Kuaté, D.2    Ngondi, J.L.3    Oben, J.E.4
  • 21
    • 0015348189 scopus 로고
    • Estimation of the concentration of low density lipoprotein in plasma, without use of the preventive ultracentrifuge
    • W.T. Friedewald, R.I. Levy, and D.S. Fredrickson Estimation of the concentration of low density lipoprotein in plasma, without use of the preventive ultracentrifuge Clin. Chem. 18 1972 499 502
    • (1972) Clin. Chem. , vol.18 , pp. 499-502
    • Friedewald, W.T.1    Levy, R.I.2    Fredrickson, D.S.3
  • 22
    • 84947035354 scopus 로고    scopus 로고
    • Medicinal plants used as excipients in the history in Ghanaian herbal medicine
    • S.H. Freiesleben, J. Soelberg, and A.K. Jäger Medicinal plants used as excipients in the history in Ghanaian herbal medicine J. Ethnopharmacol. 174 2015 561 568 (10.1016/j.jep.2015.03.005)
    • (2015) J. Ethnopharmacol. , vol.174 , pp. 561-568
    • Freiesleben, S.H.1    Soelberg, J.2    Jäger, A.K.3
  • 23
    • 84865971180 scopus 로고    scopus 로고
    • Phenolic content and total antioxidant capacity of local spices in Nigeria
    • B.O. George, and E. Osioma Phenolic content and total antioxidant capacity of local spices in Nigeria Afr. J. Food Sci. 5 2011 741 746
    • (2011) Afr. J. Food Sci. , vol.5 , pp. 741-746
    • George, B.O.1    Osioma, E.2
  • 24
    • 0033694663 scopus 로고    scopus 로고
    • Molecular mechanisms of insulin resistance and the role of the adipocyte
    • G.S. Hotamisligil Molecular mechanisms of insulin resistance and the role of the adipocyte Int. J. Obes. Relat. Metab. Dis. 24 2000 S23 S27
    • (2000) Int. J. Obes. Relat. Metab. Dis. , vol.24 , pp. S23-S27
    • Hotamisligil, G.S.1
  • 25
    • 79960840065 scopus 로고    scopus 로고
    • Antihyperglycemic and antioxidative potential of Psidium guajava fruit in streptozotocin-induced diabetic rats
    • C. Huang, M. Yin, and L. Chiu Antihyperglycemic and antioxidative potential of Psidium guajava fruit in streptozotocin-induced diabetic rats Food Chem. Toxicol. 49 2011 2189 2195
    • (2011) Food Chem. Toxicol. , vol.49 , pp. 2189-2195
    • Huang, C.1    Yin, M.2    Chiu, L.3
  • 26
    • 34047168311 scopus 로고    scopus 로고
    • Low dose streptozotocin (STZ) combined with high energy intake can effectively induce type 2 diabetes through altering the related gene expression
    • J.W. Hui, X.J. Yuan, J.N. Wan-Shen, Y.J. Tao-Wu, and W.F. Zheng Low dose streptozotocin (STZ) combined with high energy intake can effectively induce type 2 diabetes through altering the related gene expression Asian Pac. J. Clin. Nutr. 16 2007 412 417
    • (2007) Asian Pac. J. Clin. Nutr. , vol.16 , pp. 412-417
    • Hui, J.W.1    Yuan, X.J.2    Wan-Shen, J.N.3    Tao-Wu, Y.J.4    Zheng, W.F.5
  • 28
    • 84902553093 scopus 로고    scopus 로고
    • Butanol fraction of Khaya senegalensis root modulates β-cell function and ameliorates diabetes-related biochemical parameters in a type 2 diabetes rat model
    • M.A. Ibrahim, and M.S. Islam Butanol fraction of Khaya senegalensis root modulates β-cell function and ameliorates diabetes-related biochemical parameters in a type 2 diabetes rat model J. Ethnopharmacol. 154 2014 832 838
    • (2014) J. Ethnopharmacol. , vol.154 , pp. 832-838
    • Ibrahim, M.A.1    Islam, M.S.2
  • 29
    • 84870816352 scopus 로고    scopus 로고
    • International Diabetes Federation (IDF) 6th ed. Available at, Accessed on 13th March, 2015
    • International Diabetes Federation (IDF), 2014. Diabetes Atlas. 6th ed. Available at ((http://www.idf.org/diabetesatlas/update-2014)), Accessed on 13th March, 2015.
    • (2014) Diabetes Atlas
  • 31
    • 84857937634 scopus 로고    scopus 로고
    • Influence of Xylopia aethiopica fruits on some hematological and biochemical profile
    • N. Johnkennedy, E. Adamma, A. Austin, and N.E.C. Njoku Influence of Xylopia aethiopica fruits on some hematological and biochemical profile Al Ameen J. Med. Sci. 4 2011 191 196
    • (2011) Al Ameen J. Med. Sci. , vol.4 , pp. 191-196
    • Johnkennedy, N.1    Adamma, E.2    Austin, A.3    Njoku, N.E.C.4
  • 32
    • 11144221882 scopus 로고    scopus 로고
    • Composition and antioxidant activity of the essential oils of Xylopia aethiopica (Dun) A. Rich. (Annonaceae) leaves, stem bark, root bark, and fresh and dried fruits, growing in Ghana
    • A. Karioti, D. Hadjipavlou-Litina, M.L.K. Mensah, T.C. Fleischer, and H. Skaltsa Composition and antioxidant activity of the essential oils of Xylopia aethiopica (Dun) A. Rich. (Annonaceae) leaves, stem bark, root bark, and fresh and dried fruits, growing in Ghana J. Agric. Food Chem. 52 2004 8094 8098
    • (2004) J. Agric. Food Chem. , vol.52 , pp. 8094-8098
    • Karioti, A.1    Hadjipavlou-Litina, D.2    Mensah, M.L.K.3    Fleischer, T.C.4    Skaltsa, H.5
  • 34
    • 84969392472 scopus 로고    scopus 로고
    • Antifertility effects of ethanolic extract of Xylopia aethiopica on male reproductive organ of Wister rats
    • E.N. Kingsley Antifertility effects of ethanolic extract of Xylopia aethiopica on male reproductive organ of Wister rats Am. J. Med. Med. Sci. 2 2012 12 15
    • (2012) Am. J. Med. Med. Sci. , vol.2 , pp. 12-15
    • Kingsley, E.N.1
  • 35
    • 84882277613 scopus 로고    scopus 로고
    • Cytotoxicity and modes of action of four Cameroonian dietary spices ethno-medically used to treat Cancers: Echinops giganteus, Xylopia aethiopica, Imperata cylindrica and Piper capense
    • V. Kuete, L.P. Sandjo, B. Wiench, and T. Efferth Cytotoxicity and modes of action of four Cameroonian dietary spices ethno-medically used to treat Cancers: Echinops giganteus, Xylopia aethiopica, Imperata cylindrica and Piper capense J. Ethnopharmacol. 149 2013 243 253
    • (2013) J. Ethnopharmacol. , vol.149 , pp. 243-253
    • Kuete, V.1    Sandjo, L.P.2    Wiench, B.3    Efferth, T.4
  • 37
    • 16344380411 scopus 로고    scopus 로고
    • Cuminaldehyde: Aldose reductase and α-glucosidase inhibitor derived from Cuminum cyminum L. Seeds
    • H.S. Lee Cuminaldehyde: aldose reductase and α-glucosidase inhibitor derived from Cuminum cyminum L. seeds J. Agric. Food Chem. 53 2005 2446 2450
    • (2005) J. Agric. Food Chem. , vol.53 , pp. 2446-2450
    • Lee, H.S.1
  • 38
    • 78650668913 scopus 로고    scopus 로고
    • Synthesis of butyl-isobutyl-phthalate and its interaction with α-glucosidase in vitro
    • M. Liu, W. Zhang, L. Qiu, and X. Lin Synthesis of butyl-isobutyl-phthalate and its interaction with α-glucosidase in vitro J. Biochem. 149 2011 27 33
    • (2011) J. Biochem. , vol.149 , pp. 27-33
    • Liu, M.1    Zhang, W.2    Qiu, L.3    Lin, X.4
  • 39
    • 0033379165 scopus 로고    scopus 로고
    • The relation of white blood cell count and atherogenic index ratio of LDL-cholesterol to HDL-cholesterol in Taiwan school children
    • C.S. Liu, C.C. Lin, and T.C. Li The relation of white blood cell count and atherogenic index ratio of LDL-cholesterol to HDL-cholesterol in Taiwan school children Acta Paediatr. Taiwanica 40 1999 319 324
    • (1999) Acta Paediatr. Taiwanica , vol.40 , pp. 319-324
    • Liu, C.S.1    Lin, C.C.2    Li, T.C.3
  • 40
    • 0014738371 scopus 로고
    • Determination of glycogen in small tissue samples
    • S. Lo, J.C. Russel, and A.W. Taylor Determination of glycogen in small tissue samples J. Appl. Physiol. 28 1970 234 236
    • (1970) J. Appl. Physiol. , vol.28 , pp. 234-236
    • Lo, S.1    Russel, J.C.2    Taylor, A.W.3
  • 42
    • 84969392472 scopus 로고    scopus 로고
    • Antifertility effects of ethanolic extract of Xylopia aethiopica on male reproductive organ of Wister rats
    • E.K. Nwangwa Antifertility effects of ethanolic extract of Xylopia aethiopica on male reproductive organ of Wister rats Am. J. Med. Med. Sci. 2 2012 12 15
    • (2012) Am. J. Med. Med. Sci. , vol.2 , pp. 12-15
    • Nwangwa, E.K.1
  • 43
    • 79952075828 scopus 로고    scopus 로고
    • Hypolipidemic and antioxidant potentials of Xylopia aethiopica seed extract in hypercholesterolemic rats
    • S.O. Nwozo, B.F. Orojobi, and O.A. Adaramoye Hypolipidemic and antioxidant potentials of Xylopia aethiopica seed extract in hypercholesterolemic rats J. Med. Food 14 2011 114 119
    • (2011) J. Med. Food , vol.14 , pp. 114-119
    • Nwozo, S.O.1    Orojobi, B.F.2    Adaramoye, O.A.3
  • 46
    • 41749119671 scopus 로고    scopus 로고
    • Evaluation of acute and subacute toxicity of Alstonia congensis Engler (Apocynaceae) bark and Xylopia aethiopica (Dunal) A. Rich (Annonaceae) fruits mixtures used in the treatment of diabetes
    • S. Ogbonnia, A.A. Adekunle, M.K. Bosa, and V.N. Enwuru Evaluation of acute and subacute toxicity of Alstonia congensis Engler (Apocynaceae) bark and Xylopia aethiopica (Dunal) A. Rich (Annonaceae) fruits mixtures used in the treatment of diabetes Afr. J. Biotechnol. 7 2008 701 705
    • (2008) Afr. J. Biotechnol. , vol.7 , pp. 701-705
    • Ogbonnia, S.1    Adekunle, A.A.2    Bosa, M.K.3    Enwuru, V.N.4
  • 50
    • 84872772638 scopus 로고    scopus 로고
    • An 'Avalanche' of plant species for the traditional cure of diabetes mellitus in South-Western Nigeria
    • M.O. Soladoye, E.C. Chukwuma, and F.P. Owa An 'Avalanche' of plant species for the traditional cure of diabetes mellitus in South-Western Nigeria J. Nat. Prod. Plant Res. 2 2012 60 72
    • (2012) J. Nat. Prod. Plant Res. , vol.2 , pp. 60-72
    • Soladoye, M.O.1    Chukwuma, E.C.2    Owa, F.P.3
  • 51
    • 70350322825 scopus 로고    scopus 로고
    • Haematological properties of aqueous extracts of Phyllantus amarus (Schum and Thonn.) and Xylopia aethiopica (Dunal) A. Rich in albino rats
    • I.A. Taiwo, B.O. Oboh, and P.N. Francis-Garuba Haematological properties of aqueous extracts of Phyllantus amarus (Schum and Thonn.) and Xylopia aethiopica (Dunal) A. Rich in albino rats Ethnomedicine 3 2009 99 103
    • (2009) Ethnomedicine , vol.3 , pp. 99-103
    • Taiwo, I.A.1    Oboh, B.O.2    Francis-Garuba, P.N.3
  • 52
    • 78049305342 scopus 로고    scopus 로고
    • In vitro antisickling effects of Xylopia aethiopica and Monodora myristica
    • A.A. Uwakwe, and R.N. Nwaoguikpe In vitro antisickling effects of Xylopia aethiopica and Monodora myristica J. Med. Plants Res. 2 2008 119 124
    • (2008) J. Med. Plants Res. , vol.2 , pp. 119-124
    • Uwakwe, A.A.1    Nwaoguikpe, R.N.2
  • 53
    • 84862166097 scopus 로고    scopus 로고
    • Fructose-fed streptozotocin-injected rat: An alternative model for type 2 diabetes
    • R. Wilson, and M.S. Islam Fructose-fed streptozotocin-injected rat: an alternative model for type 2 diabetes Pharmacol. Rep. 64 2012 129 139
    • (2012) Pharmacol. Rep. , vol.64 , pp. 129-139
    • Wilson, R.1    Islam, M.S.2


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