-
1
-
-
38049028459
-
Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts
-
Nakagawa, M. et al. Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts. Nat. Biotechnol. 26, 101-106 (2008).
-
(2008)
Nat. Biotechnol
, vol.26
, pp. 101-106
-
-
Nakagawa, M.1
-
2
-
-
34249880066
-
Generation of germline-competent induced pluripotent stem cells
-
Okita, K., Ichisaka, T. & Yamanaka, S. Generation of germline-competent induced pluripotent stem cells. Nature 448, 313-317 (2007).
-
(2007)
Nature
, vol.448
, pp. 313-317
-
-
Okita, K.1
Ichisaka, T.2
Yamanaka, S.3
-
3
-
-
84856007232
-
The promise of induced pluripotent stem cells in research and therapy
-
Robinton, D. A. & Daley, G. Q. The promise of induced pluripotent stem cells in research and therapy. Nature 481, 295-305 (2012).
-
(2012)
Nature
, vol.481
, pp. 295-305
-
-
Robinton, D.A.1
Daley, G.Q.2
-
4
-
-
84868191453
-
The many roads to Rome: Induction of neural precursor cells from fibroblasts
-
Lujan, E. & Wernig, M. The many roads to Rome: induction of neural precursor cells from fibroblasts. Curr. Opin. Genet. Dev. 22, 517-522 (2012).
-
(2012)
Curr. Opin. Genet. Dev.
, vol.22
, pp. 517-522
-
-
Lujan, E.1
Wernig, M.2
-
5
-
-
79956357347
-
Direct reprogramming of mouse fibroblasts to neural progenitors
-
Kim, J. et al. Direct reprogramming of mouse fibroblasts to neural progenitors. Proc. Natl Acad. Sci. USA 108, 7838-7843 (2011).
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 7838-7843
-
-
Kim, J.1
-
6
-
-
84857136772
-
Direct conversion of mouse fibroblasts to self-renewing, tripotent neural precursor cells
-
Lujan, E., Chanda, S., Ahlenius, H., Sudhof, T. C. & Wernig, M. Direct conversion of mouse fibroblasts to self-renewing, tripotent neural precursor cells. Proc. Natl Acad. Sci. USA 109, 2527-2532 (2012).
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, pp. 2527-2532
-
-
Lujan, E.1
Chanda, S.2
Ahlenius, H.3
Sudhof, T.C.4
Wernig, M.5
-
7
-
-
84855516409
-
Direct reprogramming of Sertoli cells into multipotent neural stem cells by defined factors
-
Sheng, C. et al. Direct reprogramming of Sertoli cells into multipotent neural stem cells by defined factors. Cell Res. 22, 208-218 (2012).
-
(2012)
Cell Res.
, vol.22
, pp. 208-218
-
-
Sheng, C.1
-
8
-
-
84859555919
-
Direct conversion of fibroblasts into stably expandable neural stem cells
-
Thier, M. et al. Direct conversion of fibroblasts into stably expandable neural stem cells. Cell Stem Cell 10, 473-479 (2012).
-
(2012)
Cell Stem Cell
, vol.10
, pp. 473-479
-
-
Thier, M.1
-
9
-
-
84863625049
-
Direct reprogramming of mouse and human fibroblasts into multipotent neural stem cells with a single factor
-
Ring, K. L. et al. Direct reprogramming of mouse and human fibroblasts into multipotent neural stem cells with a single factor. Cell Stem Cell 11, 100-109 (2012).
-
(2012)
Cell Stem Cell
, vol.11
, pp. 100-109
-
-
Ring, K.L.1
-
10
-
-
84862777308
-
Direct reprogramming of fibroblasts into neural stem cells by defined factors
-
Han, D. W. et al. Direct reprogramming of fibroblasts into neural stem cells by defined factors. Cell Stem Cell 10, 465-472 (2012).
-
(2012)
Cell Stem Cell
, vol.10
, pp. 465-472
-
-
Han, D.W.1
-
11
-
-
68049117331
-
Glioblastoma multiforme: A review of where we have been and where we are going
-
Adamson, C. et al. Glioblastoma multiforme: a review of where we have been and where we are going. Expert Opin. Investig. Drugs 18, 1061-1083 (2009).
-
(2009)
Expert Opin. Investig. Drugs
, vol.18
, pp. 1061-1083
-
-
Adamson, C.1
-
12
-
-
65349121788
-
Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-Year analysis of the EORTC-NCIC trial
-
Stupp, R. et al. Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial. Lancet Oncol. 10, 459-466 (2009).
-
(2009)
Lancet Oncol.
, vol.10
, pp. 459-466
-
-
Stupp, R.1
-
13
-
-
84863827012
-
A first-generation multi-functional cytokine for simultaneous optical tracking and tumour therapy
-
Hingtgen, S. et al. A first-generation multi-functional cytokine for simultaneous optical tracking and tumour therapy. PLoS ONE 7, e40234 (2012).
-
(2012)
PLoS ONE
, vol.7
-
-
Hingtgen, S.1
-
14
-
-
56249143130
-
Targeting multiple pathways in gliomas with stem cell and viral delivered S-TRAIL and Temozolomide
-
Hingtgen, S. et al. Targeting multiple pathways in gliomas with stem cell and viral delivered S-TRAIL and Temozolomide. Mol. Cancer Ther. 7, 3575-3585 (2008).
-
(2008)
Mol. Cancer Ther.
, vol.7
, pp. 3575-3585
-
-
Hingtgen, S.1
-
15
-
-
77950978854
-
A novel molecule integrating therapeutic and diagnostic activities reveals multiple aspects of stem cell-based therapy
-
Hingtgen, S. D., Kasmieh, R., van de Water, J., Weissleder, R. & Shah, K. A novel molecule integrating therapeutic and diagnostic activities reveals multiple aspects of stem cell-based therapy. Stem Cells 28, 832-841 (2010).
-
(2010)
Stem Cells
, vol.28
, pp. 832-841
-
-
Hingtgen, S.D.1
Kasmieh, R.2
Van De Water, J.3
Weissleder, R.4
Shah, K.5
-
16
-
-
77957724478
-
The use of neural stem cells in cancer gene therapy: Predicting the path to the clinic
-
Ahmed, A. U., Alexiades, N. G. & Lesniak, M. S. The use of neural stem cells in cancer gene therapy: predicting the path to the clinic. Curr. Opin. Mol. Ther. 12, 546-552 (2010).
-
(2010)
Curr. Opin. Mol. Ther.
, vol.12
, pp. 546-552
-
-
Ahmed, A.U.1
Alexiades, N.G.2
Lesniak, M.S.3
-
17
-
-
79956217683
-
Translating stem cell studies to the clinic for CNS repair: Current state of the art and the need for a Rosetta stone
-
Aboody, K., Capela, A., Niazi, N., Stern, J. H. & Temple, S. Translating stem cell studies to the clinic for CNS repair: current state of the art and the need for a Rosetta stone. Neuron 70, 597-613 (2011).
-
(2011)
Neuron
, vol.70
, pp. 597-613
-
-
Aboody, K.1
Capela, A.2
Niazi, N.3
Stern, J.H.4
Temple, S.5
-
18
-
-
84878335302
-
Neural stem cell-mediated enzyme/prodrug therapy for glioma: Preclinical studies
-
Aboody, K. S. et al. Neural stem cell-mediated enzyme/prodrug therapy for glioma: preclinical studies. Sci. Transl. Med. 5, 184ra159 (2013).
-
(2013)
Sci. Transl. Med.
, vol.5
-
-
Aboody, K.S.1
-
19
-
-
77954071766
-
An improved, standardised protocol for the isolation, enrichment and targeted neural differentiation of Nestin + progenitors from adult human dermis
-
Ernst, N. et al. An improved, standardised protocol for the isolation, enrichment and targeted neural differentiation of Nestin + progenitors from adult human dermis. Exp. Dermatol. 19, 549-555 (2010).
-
(2010)
Exp. Dermatol.
, vol.19
, pp. 549-555
-
-
Ernst, N.1
-
20
-
-
0037108871
-
The use of interleukin 12-secreting neural stem cells for the treatment of intracranial glioma
-
Ehtesham, M. et al. The use of interleukin 12-secreting neural stem cells for the treatment of intracranial glioma. Cancer Res. 62, 5657-5663 (2002).
-
(2002)
Cancer Res.
, vol.62
, pp. 5657-5663
-
-
Ehtesham, M.1
-
21
-
-
63849225752
-
Human glioblastoma-derived cancer stem cells: Establishment of invasive glioma models and treatment with oncolytic herpes simplex virus vectors
-
Wakimoto, H. et al. Human glioblastoma-derived cancer stem cells: establishment of invasive glioma models and treatment with oncolytic herpes simplex virus vectors. Cancer Res. 69, 3472-3481 (2009).
-
(2009)
Cancer Res.
, vol.69
, pp. 3472-3481
-
-
Wakimoto, H.1
-
22
-
-
77950978854
-
Determining multiple aspects of stem cell-based therapies using novel diagnostic and therapeutic multifunctional molecules
-
Hingtgen, S. D., Kasmieh, R., van de Water, J., Weissleder, R. & Shah, K. Determining multiple aspects of stem cell-based therapies using novel diagnostic and therapeutic multifunctional molecules. Stem Cells 28, 832-841 (2010).
-
(2010)
Stem Cells
, vol.28
, pp. 832-841
-
-
Hingtgen, S.D.1
Kasmieh, R.2
Van De Water, J.3
Weissleder, R.4
Shah, K.5
-
23
-
-
84856263167
-
Encapsulated therapeutic stem cells implanted in the tumour resection cavity induce cell death in gliomas
-
Kauer, T. M., Figueiredo, J. L., Hingtgen, S. & Shah, K. Encapsulated therapeutic stem cells implanted in the tumour resection cavity induce cell death in gliomas. Nat. Neurosci. 15, 197-204 (2011).
-
(2011)
Nat. Neurosci
, vol.15
, pp. 197-204
-
-
Kauer, T.M.1
Figueiredo, J.L.2
Hingtgen, S.3
Shah, K.4
-
24
-
-
63849148548
-
Assessment of therapeutic efficacy and fate of engineered human mesenchymal stem cells for cancer therapy
-
Sasportas, L. S. et al. Assessment of therapeutic efficacy and fate of engineered human mesenchymal stem cells for cancer therapy. Proc. Natl Acad. Sci. USA 106, 4822-4827 (2009).
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 4822-4827
-
-
Sasportas, L.S.1
-
26
-
-
43049088843
-
Stem and progenitor cell-mediated tumour selective gene therapy
-
Aboody, K. S., Najbauer, J. & Danks, M. K. Stem and progenitor cell-mediated tumour selective gene therapy. Gene Ther. 15, 739-752 (2008).
-
(2008)
Gene Ther.
, vol.15
, pp. 739-752
-
-
Aboody, K.S.1
Najbauer, J.2
Danks, M.K.3
-
27
-
-
80053480063
-
A comparative study of neural and mesenchymal stem cell-based carriers for oncolytic adenovirus in a model of malignant glioma
-
Ahmed, A. U. et al. A comparative study of neural and mesenchymal stem cell-based carriers for oncolytic adenovirus in a model of malignant glioma. Mol. Pharm. 8, 1559-1572 (2011).
-
(2011)
Mol. Pharm.
, vol.8
, pp. 1559-1572
-
-
Ahmed, A.U.1
-
28
-
-
84911477643
-
Advances in stem cells, induced pluripotent stem cells, and engineered cells: Delivery vehicles for anti-glioma therapy
-
Young, J. S. et al. Advances in stem cells, induced pluripotent stem cells, and engineered cells: delivery vehicles for anti-glioma therapy. Expert Opin. Drug. Deliv. 11, 1733-1746 (2014).
-
(2014)
Expert Opin. Drug. Deliv
, vol.11
, pp. 1733-1746
-
-
Young, J.S.1
-
29
-
-
82855161307
-
Migration and fate of therapeutic stem cells in different brain disease models
-
Carney, B. J. & Shah, K. Migration and fate of therapeutic stem cells in different brain disease models. Neuroscience 197, 37-47 (2011).
-
(2011)
Neuroscience
, vol.197
, pp. 37-47
-
-
Carney, B.J.1
Shah, K.2
-
30
-
-
49649114875
-
Transmembrane protein 18 enhances the tropism of neural stem cells for glioma cells
-
Jurvansuu, J. et al. Transmembrane protein 18 enhances the tropism of neural stem cells for glioma cells. Cancer Res. 68, 4614-4622 (2008).
-
(2008)
Cancer Res.
, vol.68
, pp. 4614-4622
-
-
Jurvansuu, J.1
-
31
-
-
65849172454
-
Role of monocyte chemoattractant protein-1 (MCP-1/CCL2) in migration of neural progenitor cells toward glial tumours
-
Magge, S. N. et al. Role of monocyte chemoattractant protein-1 (MCP-1/CCL2) in migration of neural progenitor cells toward glial tumours. J. Neurosci. Res. 87, 1547-1555 (2009).
-
(2009)
J. Neurosci. Res.
, vol.87
, pp. 1547-1555
-
-
Magge, S.N.1
-
32
-
-
33745217891
-
Acute injury directs the migration, proliferation, and differentiation of solid organ stem cells: Evidence from the effect of hypoxia-ischemia in the CNS on clonal 'reporter' neural stem cells
-
Park, K. I. et al. Acute injury directs the migration, proliferation, and differentiation of solid organ stem cells: evidence from the effect of hypoxia-ischemia in the CNS on clonal 'reporter' neural stem cells. Exp. Neurol. 199, 156-178 (2006).
-
(2006)
Exp. Neurol.
, vol.199
, pp. 156-178
-
-
Park, K.I.1
-
33
-
-
84871403430
-
The roles of hypoxia-inducible factors in regulating neural stem cells migration to glioma stem cells and determinating their fates
-
Zhang, S., Luo, X., Wan, F. & Lei, T. The roles of hypoxia-inducible factors in regulating neural stem cells migration to glioma stem cells and determinating their fates. Neurochem. Res. 37, 2659-2666 (2012).
-
(2012)
Neurochem. Res.
, vol.37
, pp. 2659-2666
-
-
Zhang, S.1
Luo, X.2
Wan, F.3
Lei, T.4
-
34
-
-
57749089644
-
Neural stem cell tropism to glioma: Critical role of tumour hypoxia
-
Zhao, D. et al. Neural stem cell tropism to glioma: critical role of tumour hypoxia. Mol. Cancer Res. 6, 1819-1829 (2008).
-
(2008)
Mol. Cancer Res.
, vol.6
, pp. 1819-1829
-
-
Zhao, D.1
-
35
-
-
84863445875
-
Induced neural stem cells: A new tool for studying neural development and neurological disorders
-
Liu, G. H., Yi, F., Suzuki, K., Qu, J. & Izpisua Belmonte, J. C. Induced neural stem cells: a new tool for studying neural development and neurological disorders. Cell Res. 22, 1087-1091 (2012).
-
(2012)
Cell Res.
, vol.22
, pp. 1087-1091
-
-
Liu, G.H.1
Yi, F.2
Suzuki, K.3
Qu, J.4
Izpisua Belmonte, J.C.5
-
36
-
-
84860488219
-
Genetically engineered mouse models of diffuse gliomas
-
Schmid, R. S., Vitucci, M. & Miller, C. R. Genetically engineered mouse models of diffuse gliomas. Brain Res. Bull. 88, 72-79 (2012).
-
(2012)
Brain Res. Bull
, vol.88
, pp. 72-79
-
-
Schmid, R.S.1
Vitucci, M.2
Miller, C.R.3
-
37
-
-
84886428812
-
Integration-free methods for generating induced pluripotent stem cells
-
Zhou, Y. Y. & Zeng, F. Integration-free methods for generating induced pluripotent stem cells. Genomics Proteomics Bioinformatics 11, 284-287 (2013).
-
(2013)
Genomics Proteomics Bioinformatics
, vol.11
, pp. 284-287
-
-
Zhou, Y.Y.1
Zeng, F.2
-
38
-
-
84868359023
-
Nonviral direct conversion of primary mouse embryonic fibroblasts to neuronal cells
-
Adler, A. et al. Nonviral direct conversion of primary mouse embryonic fibroblasts to neuronal cells. Mol. Ther. 1, e32 (2012).
-
(2012)
Mol. Ther.
, vol.1
, pp. e32
-
-
Adler, A.1
-
39
-
-
84856263167
-
Encapsulated therapeutic stem cells implanted in the tumour resection cavity induce cell death in gliomas
-
Kauer, T. M., Figueiredo, J. L., Hingtgen, S. & Shah, K. Encapsulated therapeutic stem cells implanted in the tumour resection cavity induce cell death in gliomas. Nat. Neurosci. 15, 197-204 (2012).
-
(2012)
Nat. Neurosci
, vol.15
, pp. 197-204
-
-
Kauer, T.M.1
Figueiredo, J.L.2
Hingtgen, S.3
Shah, K.4
-
40
-
-
77950502115
-
A hierarchy of self-renewing tumour-initiating cell types in glioblastoma
-
Chen, R. et al. A hierarchy of self-renewing tumour-initiating cell types in glioblastoma. Cancer Cell 17, 362-375 (2010).
-
(2010)
Cancer Cell
, vol.17
, pp. 362-375
-
-
Chen, R.1
-
41
-
-
7944234370
-
Optimized large-scale production of high titer lentivirus vector pseudotypes
-
Sena-Esteves, M., Tebbets, J. C., Steffens, S., Crombleholme, T. & Flake, A. W. Optimized large-scale production of high titer lentivirus vector pseudotypes. J. Virol. Methods 122, 131-139 (2004).
-
(2004)
J. Virol. Methods
, vol.122
, pp. 131-139
-
-
Sena-Esteves, M.1
Tebbets, J.C.2
Steffens, S.3
Crombleholme, T.4
Flake, A.W.5
-
42
-
-
84879300244
-
Real-time multi-modality imaging of glioblastoma tumour resection and recurrence
-
Hingtgen, S. et al. Real-time multi-modality imaging of glioblastoma tumour resection and recurrence. J. Neurooncol. 111, 153-161 (2013).
-
(2013)
J. Neurooncol
, vol.111
, pp. 153-161
-
-
Hingtgen, S.1
-
43
-
-
18544399146
-
Measuring chemotaxis and chemokinesis: The under-agarose cell migration assay
-
Heit, B. & Kubes, P. Measuring chemotaxis and chemokinesis: the under-agarose cell migration assay. Sci. STKE 2003, PL5 (2003).
-
(2003)
Sci. STKE
, vol.2003
, pp. PL5
-
-
Heit, B.1
Kubes, P.2
|