Oxyntomodulin regulates resetting of the liver circadian clock by food

eLife

Volumn 2015, Issue 4, 2015, Pages

  Landgraf, Dominic ^a,d   Tsang, Anthony H ^a,b   Leliavski, Alexei ^a,b   Koch, Christiane E ^b   Barclay, Johanna L ^a   Drucker, Daniel J ^c   Oster, Henrik ^a,b  

^a MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

^b UNIVERSITY OF LÜBECK   (Germany)

^c MOUNT SINAI HOSPITAL   (Canada)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Circadian clock; Food resetting; Liver; Oxyntomodulin; Per induction

Indexed keywords

CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; DEXAMETHASONE; EXENDIN 4; G PROTEIN COUPLED RECEPTOR; GLICENTIN; GLUCAGON; GLUCAGON LIKE PEPTIDE 1; GLUCAGON LIKE PEPTIDE 2; INSULIN; LUCIFERASE; N METHYL DEXTRO ASPARTIC ACID; OXYNTOMODULIN; PROGLUCAGON DERIVATIVE; CIRCADIAN RHYTHM SIGNALING PROTEIN; PER1 PROTEIN, MOUSE; PER2 PROTEIN, MOUSE;

ADULT; ANIMAL TISSUE; ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CIRCADIAN RHYTHM; CONTROLLED STUDY; ENERGY METABOLISM; ENZYME LINKED IMMUNOSORBENT ASSAY; FEEDING BEHAVIOR; FOOD INTAKE; GENE EXPRESSION; GENE INDUCTION; GENETIC TRANSCRIPTION; IMMUNOREACTIVITY; IN SITU HYBRIDIZATION; LIVER CIRCADIAN CLOCK; MALE; MOUSE; NONHUMAN; PHOSPHORYLATION; POLYMERASE CHAIN REACTION; RADIOIMMUNOASSAY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SUPRACHIASMATIC NUCLEUS; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; DIET RESTRICTION; DRUG EFFECTS; EATING; GENE EXPRESSION REGULATION; GENETICS; INTESTINE; LIVER; METABOLISM; MICROTOMY; PHOTOPERIODICITY; PHYSIOLOGY; SECRETION (PROCESS); TISSUE CULTURE TECHNIQUE;

MAMMALIA; MUS;

ANIMALS; CIRCADIAN CLOCKS; CIRCADIAN RHYTHM; EATING; FASTING; GENE EXPRESSION REGULATION; INSULIN; INTESTINES; LIVER; MALE; MICE; MICE, INBRED C57BL; MICROTOMY; OXYNTOMODULIN; PERIOD CIRCADIAN PROTEINS; PHOTOPERIOD; SIGNAL TRANSDUCTION; SUPRACHIASMATIC NUCLEUS; TISSUE CULTURE TECHNIQUES;

EID: 84957562919     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.06253     Document Type: Article

References (53)

1. Herichova I. Changes of physiological functions induced by shift work. Endocr Regul. 2013 Jul;47(3):159-70. Pub Med PMID: 23889486. Epub 2013/07/31. eng.
2. Rosenberg R, Doghramji PP. Is shift work making your patient sick? Emerging theories and therapies for treating shift work disorder. Postgrad Med. 2011 Sep;123(5):106-15. Pub Med PMID: 21904092.
3. Albrecht U. Timing to perfection: the biology of central and peripheral circadian clocks. Neuron. 2012 Apr 26;74(2):246-60. Pub Med PMID: 22542179.
4. Takahashi JS, Hong HK, Ko CH, McDearmon EL. The genetics of mammalian circadian order and disorder: implications for physiology and disease. Nat Rev Genet. 2008 Oct;9(10):764-75. Pub Med PMID: 18802415. Epub 2008/09/20. eng.
5. Yan J, Wang H, Liu Y, Shao C. Analysis of gene regulatory networks in the mammalian circadian rhythm. PLoS computational biology. 2008 Oct;4(10):e1000193. Pub Med PMID: 18846204. Pubmed Central PMCID: 2543109.
6. Golombek DA, Rosenstein RE. Physiology of circadian entrainment. Physiol Rev. 2010 Jul;90(3):1063-102. Pub Med PMID: 20664079.
7. Dibner C, Schibler U, Albrecht U. The mammalian circadian timing system: organization and coordination of central and peripheral clocks. Annual review of physiology. 2010 Mar 17;72:517-49. Pub Med PMID: 20148687. Epub 2010/02/13. eng.
8. Stokkan KA, Yamazaki S, Tei H, Sakaki Y, Menaker M. Entrainment of the circadian clock in the liver by feeding. Science. 2001 Jan 19;291(5503):490-3. Pub Med PMID: 11161204.
9. Damiola F, Le Minh N, Preitner N, Kornmann B, Fleury-Olela F, Schibler U. Restricted feeding uncouples circadian oscillators in peripheral tissues from the central pacemaker in the suprachiasmatic nucleus. Genes Dev. 2000 Dec 1;14(23):2950-61. Pub Med PMID: 11114885.
10. Lowden A, Moreno C, Holmback U, Lennernas M, Tucker P. Eating and shift work-effects on habits, metabolism and performance. Scandinavian journal of work, environment & health. 2010 Mar;36(2):150-62. Pub Med PMID: 20143038.
11. Arble DM, Bass J, Laposky AD, Vitaterna MH, Turek FW. Circadian timing of food intake contributes to weight gain. Obesity (Silver Spring). 2009 Nov;17(11):2100-2. Pub Med PMID: 19730426. Pubmed Central PMCID: 3499064.
12. Hatori M, Vollmers C, Zarrinpar A, Di Tacchio L, Bushong EA, Gill S, et al. Time-restricted feeding without reducing caloric intake prevents metabolic diseases in mice fed a high-fat diet. Cell metabolism. 2012 Jun 6;15(6):848-60. Pub Med PMID: 22608008. Epub 2012/05/23. eng.
13. Barclay JL, Husse J, Bode B, Naujokat N, Meyer-Kovac J, Schmid SM, et al. Circadian desynchrony promotes metabolic disruption in a mouse model of shiftwork. PLoS One. 2012;7(5):e37150. Pub Med PMID: 22629359. Pubmed Central PMCID: 3357388.
14. Antunes LC, Levandovski R, Dantas G, Caumo W, Hidalgo MP. Obesity and shift work: chronobiological aspects. Nutrition research reviews. 2010 Jun;23(1):155-68. Pub Med PMID: 20122305.
15. Tahara Y, Otsuka M, Fuse Y, Hirao A, Shibata S. Refeeding after fasting elicits insulin467 dependent regulation of Per2 and Rev-erbalpha with shifts in the liver clock. Journal of biological rhythms. 2011 Jun;26(3):230-40. Pub Med PMID: 21628550. Epub 2011/06/02. eng.
16. Chaves I, van der Horst GT, Schellevis R, Nijman RM, Koerkamp MG, Holstege FC, et al. Insulin-FOXO3 signaling modulates circadian rhythms via regulation of clock transcription. Curr Biol. 2014 Jun 2;24(11):1248-55. Pub Med PMID: 24856209.
17. Le Sauter J, Hoque N, Weintraub M, Pfaff DW, Silver R. Stomach ghrelin-secreting cells as food-entrainable circadian clocks. Proc Natl Acad Sci U S A. 2009 Aug 11;106(32):13582-7. Pub Med PMID: 19633195. Pubmed Central PMCID: 2726387.
18. Sun X, Dang F, Zhang D, Yuan Y, Zhang C, Wu Y, et al. Glucagon-CREB/CRTC2 Signaling Cascade Regulates Hepatic BMAL1. J Biol Chem. 2014 Dec 5. Pub Med PMID: 25480789.
19. Hirao A, Tahara Y, Kimura I, Shibata S. A balanced diet is necessary for proper entrainment signals of the mouse liver clock. PLoS One. 2009;4(9):e6909. Pub Med PMID: 19738906. Pubmed Central PMCID: 2734168.
20. Stanley S, Wynne K, McGowan B, Bloom S. Hormonal regulation of food intake. Physiol Rev. 2005 Oct;85(4):1131-58. Pub Med PMID: 16183909.
21. Drucker DJ. Biologic actions and therapeutic potential of the proglucagon-derived peptides. Nature clinical practice Endocrinology & metabolism. 2005 Nov;1(1):22-31. Pub Med PMID: 16929363.
22. Baldissera FG, Holst JJ, Knuhtsen S, Hilsted L, Nielsen OV. Oxyntomodulin (glicentin-(33-69)): pharmacokinetics, binding to liver cell membranes, effects on isolated perfused pig pancreas, and secretion from isolated perfused lower small intestine of pigs. Regulatory peptides. 1988 May;21(1-2):151-66. Pub Med PMID: 2839871.
23. Gros L, Thorens B, Bataille D, Kervran A. Glucagon-like peptide-1-(7-36) amide, oxyntomodulin, and glucagon interact with a common receptor in a somatostatin-secreting cell line. Endocrinology. 1993 Aug;133(2):631-8. Pub Med PMID: 8102095.
24. Yoo SH, Yamazaki S, Lowrey PL, Shimomura K, Ko CH, Buhr ED, et al. PERIOD2::LUCIFERASE real-time reporting of circadian dynamics reveals persistent circadian oscillations in mouse peripheral tissues. Proc Natl Acad Sci U S A. 2004 Apr 13;101(15):5339-46. Pub Med PMID: 14963227.
25. Balsalobre A, Brown SA, Marcacci L, Tronche F, Kellendonk C, Reichardt HM, et al. Resetting of circadian time in peripheral tissues by glucocorticoid signaling. Science. 2000 Sep 29;289(5488):2344-7. Pub Med PMID: 11009419. Epub 2000/09/29. eng.
26. Le Quellec A, Kervran A, Blache P, Ciurana AJ, Bataille D. Oxyntomodulin-like immunoreactivity: diurnal profile of a new potential enterogastrone. J Clin Endocrinol Metab. 1992 Jun;74(6):1405-9. Pub Med PMID: 1592887.
27. Jorgensen R, Kubale V, Vrecl M, Schwartz TW, Elling CE. Oxyntomodulin differentially affects glucagon-like peptide-1 receptor beta-arrestin recruitment and signaling through Galpha(s). J Pharmacol Exp Ther. 2007 Jul;322(1):148-54. Pub Med PMID: 17395766.
28. Sinclair EM, Yusta B, Streutker C, Baggio LL, Koehler J, Charron MJ, et al. Glucagon receptor signaling is essential for control of murine hepatocyte survival. Gastroenterology. 2008 Dec;135(6):2096-106. Pub Med PMID: 18809404.
29. Campos RV, Lee YC, Drucker DJ. Divergent tissue-specific and developmental expression of receptors for glucagon and glucagon-like peptide-1 in the mouse. Endocrinology. 1994. May;134(5):2156-64. Pub Med PMID: 8156917.
30. Dunphy JL, Taylor RG, Fuller PJ. Tissue distribution of rat glucagon receptor and GLP-1 receptor gene expression. Mol Cell Endocrinol. 1998 Jun 25;141(1-2):179-86. Pub Med PMID: 9723898.
31. Panjwani N, Mulvihill EE, Longuet C, Yusta B, Campbell JE, Brown TJ, et al. GLP-1 receptor activation indirectly reduces hepatic lipid accumulation but does not attenuate development of atherosclerosis in diabetic male Apo E(-/-) mice. Endocrinology. 2013 Jan;154(1):127-39. Pub Med PMID: 23183176.
32. Gonzalez GA, Montminy MR. Cyclic AMP stimulates somatostatin gene transcription by phosphorylation of CREB at serine 133. Cell. 1989 Nov 17;59(4):675-80. Pub Med PMID: 2573431.
33. Dalle S, Longuet C, Costes S, Broca C, Faruque O, Fontes G, et al. Glucagon promotes c AMP-response element-binding protein phosphorylation via activation of ERK1/2 in MIN6 cell line and isolated islets of Langerhans. J Biol Chem. 2004 May 7;279(19):20345-55. Pub Med PMID: 14988413.
34. Welsh DK, Takahashi JS, Kay SA. Suprachiasmatic nucleus: cell autonomy and network properties. Annu Rev Physiol. 2010;72:551-77. Pub Med PMID: 20148688. Pubmed Central PMCID: 3758475.
35. Lamia KA, Storch KF, Weitz CJ. Physiological significance of a peripheral tissue circadian clock. Proc Natl Acad Sci U S A. 2008 Sep 30;105(39):15172-7. Pub Med PMID: 18779586. Epub 2008/09/10. eng.
36. Salgado-Delgado R, Angeles-Castellanos M, Saderi N, Buijs RM, Escobar C. Food intake during the normal activity phase prevents obesity and circadian desynchrony in a rat model of night work. Endocrinology. 2010 Mar;151(3):1019-29. Pub Med PMID: 20080873. Epub 2010/01/19. eng.
37. Vollmers C, Gill S, Di Tacchio L, Pulivarthy SR, Le HD, Panda S. Time of feeding and the intrinsic circadian clock drive rhythms in hepatic gene expression. Proceedings of the National Academy of Sciences of the United States of America. 2009 Dec 15;106(50):21453-8. Pub Med PMID: 19940241. Pubmed Central PMCID: 2795502. Epub 2009/11/27. eng.
38. Akhtar RA, Reddy AB, Maywood ES, Clayton JD, King VM, Smith AG, et al. Circadian cycling of the mouse liver transcriptome, as revealed by c DNA microarray, is driven by the suprachiasmatic nucleus. Curr Biol. 2002 Apr 2;12(7):540-50. Pub Med PMID: 11937022.
39. Miller BH, McDearmon EL, Panda S, Hayes KR, Zhang J, Andrews JL, et al. Circadian and CLOCK-controlled regulation of the mouse transcriptome and cell proliferation. Proc Natl Acad Sci U S A. 2007 Feb 27;104(9):3342-7. Pub Med PMID: 17360649. Pubmed Central PMCID: 1802006.
40. Kornmann B, Preitner N, Rifat D, Fleury-Olela F, Schibler U. Analysis of circadian liver gene expression by ADDER, a highly sensitive method for the display of differentially expressed m RNAs. Nucleic Acids Res. 2001 Jun 1;29(11):E51-1. Pub Med PMID: 11376163.
41. Yamajuku D, Inagaki T, Haruma T, Okubo S, Kataoka Y, Kobayashi S, et al. Real-time monitoring in three-dimensional hepatocytes reveals that insulin acts as a synchronizer for liver clock. Sci Rep. 2012;2:439. Pub Med PMID: 22666542. Pubmed Central PMCID: 3365280. Epub 2012/06/06. eng.
42. Dunlap JC. Molecular bases for circadian clocks. Cell. 1999 Jan 22;96(2):271-90. Pub Med PMID: 9988221. Epub 1999/02/13. eng.
43. Lowrey PL, Takahashi JS. Mammalian circadian biology: elucidating genome-wide levels of temporal organization. Annu Rev Genomics Hum Genet. 2004;5:407-41. Pub Med PMID: 15485355. Epub 2004/10/16. eng.
44. Balsalobre A, Damiola F, Schibler U. A serum shock induces circadian gene expression in mammalian tissue culture cells. Cell. 1998 Jun 12;93(6):929-37. Pub Med PMID: 9635423.
45. Albrecht U, Sun ZS, Eichele G, Lee CC. A differential response of two putative mammalian circadian regulators, mper1 and mper2, to light. Cell. 1997 Dec 26;91(7):1055-64. Pub Med PMID: ISI:000071281400021. English.
46. Yan L, Silver R. Differential induction and localization of m Per1 and m Per2 during advancing and delaying phase shifts. Eur J Neurosci. 2002 Oct;16(8):1531-40. Pub Med PMID: 12405967. Pubmed Central PMCID: 3281755.
47. Oike H, Nagai K, Fukushima T, Ishida N, Kobori M. Feeding cues and injected nutrients induce acute expression of multiple clock genes in the mouse liver. PLoS One. 2011;6(8):e23709. Pub Med PMID: 21901130. Pubmed Central PMCID: 3162004.
48. Mayo KE, Miller LJ, Bataille D, Dalle S, Goke B, Thorens B, et al. International Union of Pharmacology. XXXV. The glucagon receptor family. Pharmacol Rev. 2003 Mar;55(1):167-94. Pub Med PMID: 12615957.
49. Tang-Christensen M, Vrang N, Larsen PJ. Glucagon-like peptide containing pathways in the regulation of feeding behaviour. Int J Obes Relat Metab Disord. 2001 Dec;25 Suppl 5:S42-7. Pub Med PMID: 11840214.
50. Blache P, Kervran A, Bataille D. Oxyntomodulin 579 and glicentin: brain-gut peptides in the rat. Endocrinology. 1988 Dec;123(6):2782-7. Pub Med PMID: 3197645.
51. Scrocchi LA, Brown TJ, Ma Clusky N, Brubaker PL, Auerbach AB, Joyner AL, et al. Glucose intolerance but normal satiety in mice with a null mutation in the glucagon-like peptide 1 receptor gene. Nat Med. 1996 Nov;2(11):1254-8. Pub Med PMID: 8898756.
52. Pfaffl MW. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res. 2001 May 1;29(9):e45. Pub Med PMID: 11328886. Epub 2001/05/09. eng.
53. Oster H, Yasui A, van der Horst GT, Albrecht U. Disruption of m Cry2 restores circadian rhythmicity in m Per2 mutant mice. Genes Dev. 2002 Oct 15;16(20):2633-8. Pub Med PMID: 12381662.