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Volumn 104, Issue 5, 2016, Pages 1162-1174

Tuning microenvironment modulus and biochemical composition promotes human mesenchymal stem cell tenogenic differentiation

Author keywords

cell microenvironment; design of experiments; hydrogel; mesenchymal stem cell; tendon

Indexed keywords

ASCORBIC ACID; BIOMIMETICS; CELL CULTURE; CELLS; COLLAGEN; CYTOLOGY; DATA ACQUISITION; DESIGN; DESIGN OF EXPERIMENTS; ENZYME ACTIVITY; GENE EXPRESSION; HYDROGELS; PEPTIDES; PLANTS (BOTANY); POLYETHYLENE GLYCOLS; PROTEINS; STEM CELLS; TISSUE; TISSUE REGENERATION;

EID: 84957544819     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.35650     Document Type: Article
Times cited : (50)

References (72)
  • 2
    • 85006217668 scopus 로고    scopus 로고
    • A retrospective review of anterior cruciate ligament reconstruction using patellar tendon: 25 Years of experience
    • Chahal J, Lee A, Heard W, Bach BR., A retrospective review of anterior cruciate ligament reconstruction using patellar tendon: 25 Years of experience. Orthop J Sport Med 2013; 1: 2325967113501789.
    • (2013) Orthop J Sport Med , vol.1
    • Chahal, J.1    Lee, A.2    Heard, W.3    Bach, B.R.4
  • 3
    • 0035526460 scopus 로고    scopus 로고
    • Donor-site morbidity and anterior knee problems after anterior cruciate ligament reconstruction using autografts
    • Kartus J, Movin T, Karlsson J., Donor-site morbidity and anterior knee problems after anterior cruciate ligament reconstruction using autografts. Arthroscopy 2001; 17: 971-980.
    • (2001) Arthroscopy , vol.17 , pp. 971-980
    • Kartus, J.1    Movin, T.2    Karlsson, J.3
  • 5
    • 84882283137 scopus 로고    scopus 로고
    • Engineering tendon and ligament tissues: Present developments towards successful clinical products
    • Rodrigues MT, Reis RL, Gomes ME., Engineering tendon and ligament tissues: Present developments towards successful clinical products. J Tissue Eng Regen Med 2013; 7: 673-686.
    • (2013) J Tissue Eng Regen Med , vol.7 , pp. 673-686
    • Rodrigues, M.T.1    Reis, R.L.2    Gomes, M.E.3
  • 6
    • 84941065724 scopus 로고    scopus 로고
    • Emerging applications of stem cell and regenerative medicine to sports injuries
    • 2325967113519935
    • Ajibade DA, Vance DD, Hare JM, Kaplan LD, Lesniak BP., Emerging applications of stem cell and regenerative medicine to sports injuries. Orthop J Sport Med 2014; 2:2325967113519935.
    • (2014) Orthop J Sport Med , vol.2
    • Ajibade, D.A.1    Vance, D.D.2    Hare, J.M.3    Kaplan, L.D.4    Lesniak, B.P.5
  • 7
    • 28444434740 scopus 로고    scopus 로고
    • Selection of cell source for ligament tissue engineering
    • Ge Z, Goh JCH, Lee EH., Selection of cell source for ligament tissue engineering. Cell Transplant 2005; 14: 573-583.
    • (2005) Cell Transplant , vol.14 , pp. 573-583
    • Ge, Z.1    Goh, J.C.H.2    Lee, E.H.3
  • 8
    • 84928555987 scopus 로고    scopus 로고
    • Physical regulation of stem cells differentiation into teno-lineage: Current strategies and future direction
    • Chen JL, Zhang W, Heng BC, Ouyang HW, Dai XS., Physical regulation of stem cells differentiation into teno-lineage: Current strategies and future direction. Cell Tissue Res 2015; 360: 195-207.
    • (2015) Cell Tissue Res , vol.360 , pp. 195-207
    • Chen, J.L.1    Zhang, W.2    Heng, B.C.3    Ouyang, H.W.4    Dai, X.S.5
  • 10
    • 77958577191 scopus 로고    scopus 로고
    • Mechanical stretch-induced changes in cell morphology and mRNA expression of tendon/ligament-associated genes in rat bone-marrow mesenchymal stem cells
    • Song G, Luo Q, Xu B, Ju Y., Mechanical stretch-induced changes in cell morphology and mRNA expression of tendon/ligament-associated genes in rat bone-marrow mesenchymal stem cells. Mol Cell Biomech 2010; 7: 165-174.
    • (2010) Mol Cell Biomech , vol.7 , pp. 165-174
    • Song, G.1    Luo, Q.2    Xu, B.3    Ju, Y.4
  • 11
    • 53049090671 scopus 로고    scopus 로고
    • Mechanoactive tenogenic differentiation of human mesenchymal stem cells
    • Kuo CK, Tuan RS., Mechanoactive tenogenic differentiation of human mesenchymal stem cells. Tissue Eng Part A 2008; 14: 1615-1627.
    • (2008) Tissue Eng Part A , vol.14 , pp. 1615-1627
    • Kuo, C.K.1    Tuan, R.S.2
  • 12
    • 80052709699 scopus 로고    scopus 로고
    • Effect of focal adhesion kinase on the regulation of realignment and tenogenic differentiation of human mesenchymal stem cells by mechanical stretch
    • Xu B, Song G, Ju Y., Effect of focal adhesion kinase on the regulation of realignment and tenogenic differentiation of human mesenchymal stem cells by mechanical stretch. Connect Tissue Res 2011; 52: 373-379.
    • (2011) Connect Tissue Res , vol.52 , pp. 373-379
    • Xu, B.1    Song, G.2    Ju, Y.3
  • 13
    • 41049110409 scopus 로고    scopus 로고
    • Time-related changes in expression of collagen types i and III and of tenascin-C in rat bone mesenchymal stem cells under co-culture with ligament fibroblasts or uniaxial stretching
    • Zhang L, Tran N, Chen H-Q, Kahn CJ-F, Marchal S, Groubatch F, Wang X., Time-related changes in expression of collagen types I and III and of tenascin-C in rat bone mesenchymal stem cells under co-culture with ligament fibroblasts or uniaxial stretching. Cell Tissue Res 2008; 332: 101-109.
    • (2008) Cell Tissue Res , vol.332 , pp. 101-109
    • Zhang, L.1    Tran, N.2    Chen, H.-Q.3    Kahn, C.-F.4    Marchal, S.5    Groubatch, F.6    Wang, X.7
  • 14
    • 84886834064 scopus 로고    scopus 로고
    • Determination of optimal cyclic uniaxial stretches for stem cell-to-tenocyte differentiation under a wide range of mechanical stretch conditions by evaluating gene expression and protein synthesis levels
    • Morita Y, Watanabe S, Ju Y, Xu B., Determination of optimal cyclic uniaxial stretches for stem cell-to-tenocyte differentiation under a wide range of mechanical stretch conditions by evaluating gene expression and protein synthesis levels. Acta Bioeng Biomech 2013; 15: 71-79.
    • (2013) Acta Bioeng Biomech , vol.15 , pp. 71-79
    • Morita, Y.1    Watanabe, S.2    Ju, Y.3    Xu, B.4
  • 15
    • 70350502204 scopus 로고    scopus 로고
    • Effect of fiber diameter and alignment of electrospun polyurethane meshes on mesenchymal progenitor cells
    • Bashur CA, Shaffer RD, Dahlgren LA, Guelcher SA, Goldstein AS., Effect of fiber diameter and alignment of electrospun polyurethane meshes on mesenchymal progenitor cells. Tissue Eng Part A 2009; 15: 2435-2445.
    • (2009) Tissue Eng Part A , vol.15 , pp. 2435-2445
    • Bashur, C.A.1    Shaffer, R.D.2    Dahlgren, L.A.3    Guelcher, S.A.4    Goldstein, A.S.5
  • 16
    • 84904039153 scopus 로고    scopus 로고
    • Structural and biochemical modification of a collagen scaffold to selectively enhance MSC tenogenic, chondrogenic, and osteogenic differentiation
    • Caliari SR, Harley BAC., Structural and biochemical modification of a collagen scaffold to selectively enhance MSC tenogenic, chondrogenic, and osteogenic differentiation. Adv Healthc Mater 2014; 3: 1086-1096.
    • (2014) Adv Healthc Mater , vol.3 , pp. 1086-1096
    • Caliari, S.R.1    Harley, B.A.C.2
  • 17
    • 79958268412 scopus 로고    scopus 로고
    • Aligned hybrid silk scaffold for enhanced differentiation of mesenchymal stem cells into ligament fibroblasts
    • Teh TKH, Toh S-L, Goh JCH., Aligned hybrid silk scaffold for enhanced differentiation of mesenchymal stem cells into ligament fibroblasts. Tissue Eng Part C Methods 2011; 17: 687-703.
    • (2011) Tissue Eng Part C Methods , vol.17 , pp. 687-703
    • Teh, T.K.H.1    Toh, S.-L.2    Goh, J.C.H.3
  • 18
    • 70349999453 scopus 로고    scopus 로고
    • Indirect co-culture with tenocytes promotes proliferation and mRNA expression of tendon/ligament related genes in rat bone marrow mesenchymal stem cells
    • Luo Q, Song G, Song Y, Xu B, Qin J, Shi Y., Indirect co-culture with tenocytes promotes proliferation and mRNA expression of tendon/ligament related genes in rat bone marrow mesenchymal stem cells. Cytotechnology 2009; 61: 1-10.
    • (2009) Cytotechnology , vol.61 , pp. 1-10
    • Luo, Q.1    Song, G.2    Song, Y.3    Xu, B.4    Qin, J.5    Shi, Y.6
  • 19
    • 33751424402 scopus 로고    scopus 로고
    • The differentiation of mesenchymal stem cells by mechanical stress or/and co-culture system
    • Lee I-C, Wang J-H, Lee Y-T, Young T-H., The differentiation of mesenchymal stem cells by mechanical stress or/and co-culture system. Biochem Biophys Res Commun 2007; 352: 147-152.
    • (2007) Biochem Biophys Res Commun , vol.352 , pp. 147-152
    • Lee, I.-C.1    Wang, J.-H.2    Lee, Y.-T.3    Young, T.-H.4
  • 20
    • 79960265593 scopus 로고    scopus 로고
    • Three-dimensional high-density co-culture with primary tenocytes induces tenogenic differentiation in mesenchymal stem cells
    • Schneider PRA, Buhrmann C, Mobasheri A, Matis U, Shakibaei M., Three-dimensional high-density co-culture with primary tenocytes induces tenogenic differentiation in mesenchymal stem cells. J Orthop Res 2011; 29: 1351-1360.
    • (2011) J Orthop Res , vol.29 , pp. 1351-1360
    • Schneider, P.R.A.1    Buhrmann, C.2    Mobasheri, A.3    Matis, U.4    Shakibaei, M.5
  • 21
    • 37349063194 scopus 로고    scopus 로고
    • Enhanced differentiation of mesenchymal stem cells co-cultured with ligament fibroblasts on gelatin/silk fibroin hybrid scaffold
    • Fan H, Liu H, Toh SL, Goh JCH., Enhanced differentiation of mesenchymal stem cells co-cultured with ligament fibroblasts on gelatin/silk fibroin hybrid scaffold. Biomaterials 2008; 29: 1017-1027.
    • (2008) Biomaterials , vol.29 , pp. 1017-1027
    • Fan, H.1    Liu, H.2    Toh, S.L.3    Goh, J.C.H.4
  • 23
  • 24
    • 84876396985 scopus 로고    scopus 로고
    • Effect of growth and differentiation factor 6 on the tenogenic differentiation of bone marrow-derived mesenchymal stem cells
    • Wei C, Ming N, Yun-Feng R, Kai-Yi Z, Qiang Z, Liang-Liang X, Kai-Ming C, Gang L, Yan W., Effect of growth and differentiation factor 6 on the tenogenic differentiation of bone marrow-derived mesenchymal stem cells. Chin Med J (Engl) 2013; 126: 1509-1516.
    • (2013) Chin Med J (Engl) , vol.126 , pp. 1509-1516
    • Wei, C.1    Ming, N.2    Yun-Feng, R.3    Kai-Yi, Z.4    Qiang, Z.5    Liang-Liang, X.6    Kai-Ming, C.7    Gang, L.8    Yan, W.9
  • 25
    • 84878590463 scopus 로고    scopus 로고
    • Tenogenic differentiation of equine adipose-tissue-derived stem cells under the influence of tensile strain, growth differentiation factors and various oxygen tensions
    • Raabe O, Shell K, Fietz D, Freitag C, Ohrndorf A, Christ HJ, Wenisch S, Arnhold S., Tenogenic differentiation of equine adipose-tissue-derived stem cells under the influence of tensile strain, growth differentiation factors and various oxygen tensions. Cell Tissue Res 2013; 352: 509-521.
    • (2013) Cell Tissue Res , vol.352 , pp. 509-521
    • Raabe, O.1    Shell, K.2    Fietz, D.3    Freitag, C.4    Ohrndorf, A.5    Christ, H.J.6    Wenisch, S.7    Arnhold, S.8
  • 27
    • 84893258445 scopus 로고    scopus 로고
    • Osteogenic differentiation of human mesenchymal stem cells on α5 integrin binding peptide hydrogels is dependent on substrate elasticity
    • Gandavarapu NR, Alge DL, Anseth KS., Osteogenic differentiation of human mesenchymal stem cells on α5 integrin binding peptide hydrogels is dependent on substrate elasticity. Biomater Sci 2014; 2: 352-361.
    • (2014) Biomater Sci , vol.2 , pp. 352-361
    • Gandavarapu, N.R.1    Alge, D.L.2    Anseth, K.S.3
  • 28
    • 40649116602 scopus 로고    scopus 로고
    • The enhancement of chondrogenic differentiation of human mesenchymal stem cells by enzymatically regulated RGD functionalities
    • Salinas CN, Anseth KS., The enhancement of chondrogenic differentiation of human mesenchymal stem cells by enzymatically regulated RGD functionalities. Biomaterials 2008; 29: 2370-2377.
    • (2008) Biomaterials , vol.29 , pp. 2370-2377
    • Salinas, C.N.1    Anseth, K.S.2
  • 29
    • 77951091885 scopus 로고    scopus 로고
    • The use of decellularized adipose tissue to provide an inductive microenvironment for the adipogenic differentiation of human adipose-derived stem cells
    • Flynn LE., The use of decellularized adipose tissue to provide an inductive microenvironment for the adipogenic differentiation of human adipose-derived stem cells. Biomaterials 2010; 31: 4715-4724.
    • (2010) Biomaterials , vol.31 , pp. 4715-4724
    • Flynn, L.E.1
  • 30
    • 77955776397 scopus 로고    scopus 로고
    • Biochemical and biomechanical gradients for directed bone marrow stromal cell differentiation toward tendon and bone
    • Sharma RI, Snedeker JG., Biochemical and biomechanical gradients for directed bone marrow stromal cell differentiation toward tendon and bone. Biomaterials 2010; 31: 7695-7704.
    • (2010) Biomaterials , vol.31 , pp. 7695-7704
    • Sharma, R.I.1    Snedeker, J.G.2
  • 31
    • 84857078848 scopus 로고    scopus 로고
    • Paracrine interactions between mesenchymal stem cells affect substrate driven differentiation toward tendon and bone phenotypes
    • Sharma RI, Snedeker JG., Paracrine interactions between mesenchymal stem cells affect substrate driven differentiation toward tendon and bone phenotypes. PLoS One 2012; 7: e31504.
    • (2012) PLoS One , vol.7 , pp. e31504
    • Sharma, R.I.1    Snedeker, J.G.2
  • 33
    • 0034672872 scopus 로고    scopus 로고
    • Scaffolds in tissue engineering bone and cartilage
    • Hutmacher DW., Scaffolds in tissue engineering bone and cartilage. Biomaterials 2000; 21: 2529-2543.
    • (2000) Biomaterials , vol.21 , pp. 2529-2543
    • Hutmacher, D.W.1
  • 35
    • 84862652414 scopus 로고    scopus 로고
    • Advances in bioactive hydrogels to probe and direct cell fate
    • DeForest CA, Anseth KS., Advances in bioactive hydrogels to probe and direct cell fate. Annu Rev Chem Biomol Eng 2012; 3: 421-444.
    • (2012) Annu Rev Chem Biomol Eng , vol.3 , pp. 421-444
    • DeForest, C.A.1    Anseth, K.S.2
  • 36
    • 0037330644 scopus 로고    scopus 로고
    • Multiple joint and skeletal patterning defects caused by single and double mutations in the mouse Gdf6 and Gdf5 genes
    • Settle SH, Rountree RB, Sinha A, Thacker A, Higgins K, Kingsley DM., Multiple joint and skeletal patterning defects caused by single and double mutations in the mouse Gdf6 and Gdf5 genes. Dev Biol 2003; 254: 116-130.
    • (2003) Dev Biol , vol.254 , pp. 116-130
    • Settle, S.H.1    Rountree, R.B.2    Sinha, A.3    Thacker, A.4    Higgins, K.5    Kingsley, D.M.6
  • 37
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
    • Livak KJ, Schmittgen TD., Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001; 25: 402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 38
    • 33749555329 scopus 로고    scopus 로고
    • Techniques for biological characterization of tissue-engineered tendon and ligament
    • Doroski DM, Brink KS, Temenoff JS., Techniques for biological characterization of tissue-engineered tendon and ligament. Biomaterials 2007; 28: 187-202.
    • (2007) Biomaterials , vol.28 , pp. 187-202
    • Doroski, D.M.1    Brink, K.S.2    Temenoff, J.S.3
  • 40
    • 84884913493 scopus 로고    scopus 로고
    • Tendon and ligament regeneration and repair: Clinical relevance and developmental paradigm
    • Yang G, Rothrauff BB, Tuan RS., Tendon and ligament regeneration and repair: clinical relevance and developmental paradigm. Birth Defects Res C Embryo Today 2013; 99: 203-222.
    • (2013) Birth Defects Res C Embryo Today , vol.99 , pp. 203-222
    • Yang, G.1    Rothrauff, B.B.2    Tuan, R.S.3
  • 41
    • 0029775681 scopus 로고    scopus 로고
    • RGD and other recognition sequences for integrins
    • Ruoslahti E., RGD and other recognition sequences for integrins. Annu Rev Cell Dev Biol 1996; 12: 697-715.
    • (1996) Annu Rev Cell Dev Biol , vol.12 , pp. 697-715
    • Ruoslahti, E.1
  • 42
    • 0034014229 scopus 로고    scopus 로고
    • The cell and developmental biology of tendons and ligaments
    • Benjamin M, Ralphs JR., The cell and developmental biology of tendons and ligaments. Int Rev Cytol 2000; 196: 85-130.
    • (2000) Int Rev Cytol , vol.196 , pp. 85-130
    • Benjamin, M.1    Ralphs, J.R.2
  • 43
    • 84884414341 scopus 로고    scopus 로고
    • Mechanical factors in embryonic tendon development: Potential cues for stem cell tenogenesis
    • Schiele NR, Marturano JE, Kuo CK., Mechanical factors in embryonic tendon development: potential cues for stem cell tenogenesis. Curr Opin Biotechnol 2013; 24: 834-840.
    • (2013) Curr Opin Biotechnol , vol.24 , pp. 834-840
    • Schiele, N.R.1    Marturano, J.E.2    Kuo, C.K.3
  • 45
    • 33747152561 scopus 로고    scopus 로고
    • Matrix elasticity directs stem cell lineage specification
    • Engler AJ, Sen S, Sweeney HL, Discher DE., Matrix elasticity directs stem cell lineage specification. Cell 2006; 126: 677-689.
    • (2006) Cell , vol.126 , pp. 677-689
    • Engler, A.J.1    Sen, S.2    Sweeney, H.L.3    Discher, D.E.4
  • 46
    • 77956218581 scopus 로고    scopus 로고
    • Connecting muscles to tendons: Tendons and musculoskeletal development in flies and vertebrates
    • Schweitzer R, Zelzer E, Volk T., Connecting muscles to tendons: Tendons and musculoskeletal development in flies and vertebrates. Development 2010; 137: 2807-2817.
    • (2010) Development , vol.137 , pp. 2807-2817
    • Schweitzer, R.1    Zelzer, E.2    Volk, T.3
  • 47
    • 79952101791 scopus 로고    scopus 로고
    • The performance of human mesenchymal stem cells encapsulated in cell-degradable polymer-peptide hydrogels
    • Anderson SB, Lin C-C, Kuntzler DV, Anseth KS., The performance of human mesenchymal stem cells encapsulated in cell-degradable polymer-peptide hydrogels. Biomaterials 2011; 32: 3564-3574.
    • (2011) Biomaterials , vol.32 , pp. 3564-3574
    • Anderson, S.B.1    Lin, C.-C.2    Kuntzler, D.V.3    Anseth, K.S.4
  • 50
    • 70349863065 scopus 로고    scopus 로고
    • Photoinitiated polymerization of PEG-diacrylate with lithium phenyl-2,4,6-trimethylbenzoylphosphinate: Polymerization rate and cytocompatibility
    • Fairbanks BD, Schwartz MP, Bowman CN, Anseth KS., Photoinitiated polymerization of PEG-diacrylate with lithium phenyl-2,4,6-trimethylbenzoylphosphinate: Polymerization rate and cytocompatibility. Biomaterials 2009; 30: 6702-6707.
    • (2009) Biomaterials , vol.30 , pp. 6702-6707
    • Fairbanks, B.D.1    Schwartz, M.P.2    Bowman, C.N.3    Anseth, K.S.4
  • 51
    • 77955666383 scopus 로고    scopus 로고
    • Mechanical properties of cellularly responsive hydrogels and their experimental determination
    • Kloxin AM, Kloxin CJ, Bowman CN, Anseth KS., Mechanical properties of cellularly responsive hydrogels and their experimental determination. Adv Mater 2010; 22: 3484-3494.
    • (2010) Adv Mater , vol.22 , pp. 3484-3494
    • Kloxin, A.M.1    Kloxin, C.J.2    Bowman, C.N.3    Anseth, K.S.4
  • 52
    • 84864408348 scopus 로고    scopus 로고
    • Small peptide functionalized thiol-ene hydrogels as culture substrates for understanding valvular interstitial cell activation and de novo tissue deposition
    • Gould ST, Darling NJ, Anseth KS., Small peptide functionalized thiol-ene hydrogels as culture substrates for understanding valvular interstitial cell activation and de novo tissue deposition. Acta Biomater 2012; 8: 3201-3209.
    • (2012) Acta Biomater , vol.8 , pp. 3201-3209
    • Gould, S.T.1    Darling, N.J.2    Anseth, K.S.3
  • 53
    • 80155134111 scopus 로고    scopus 로고
    • Controlling the fibroblastic differentiation of mesenchymal stem cells via the combination of fibrous scaffolds and connective tissue growth factor
    • Tong Z, Sant S, Khademhosseini A, Jia X., Controlling the fibroblastic differentiation of mesenchymal stem cells via the combination of fibrous scaffolds and connective tissue growth factor. Tissue Eng Part A 2011; 17: 2773-2285.
    • (2011) Tissue Eng Part A , vol.17 , pp. 2773-2285
    • Tong, Z.1    Sant, S.2    Khademhosseini, A.3    Jia, X.4
  • 54
    • 84961698286 scopus 로고    scopus 로고
    • Design of experiments
    • Ogunnaike B.A. Boca Raton, FL: CRC Press
    • Ogunnaike BA,. Design of experiments. In:, Ogunnaike BA,. Random Phenomena. Boca Raton, FL: CRC Press; 2010.
    • (2010) Random Phenomena
    • Ogunnaike, B.A.1
  • 55
    • 67649444944 scopus 로고    scopus 로고
    • Reference gene validation software for improved normalization
    • Logan J. Edwards K. Saunders N. editors. Norfolk, UK: Caister Academic Press
    • Vandesompele J, Kubista M, Pfaffl MW., Reference gene validation software for improved normalization. In:, Logan J, Edwards K, Saunders N, editors. Real-Time PCR: Current Technology and Application. Norfolk, UK: Caister Academic Press; 2009.
    • (2009) Real-Time PCR: Current Technology and Application
    • Vandesompele, J.1    Kubista, M.2    Pfaffl, M.W.3
  • 56
    • 84961707751 scopus 로고    scopus 로고
    • Statistics 512: Applied Linear Models [Internet]
    • Jennings K., Statistics 512: Applied Linear Models [Internet]. Available at: http://www.stat.purdue.edu/jennings/stat514/stat512notes/topic5.pdf.
    • Jennings, K.1
  • 58
    • 0031794779 scopus 로고    scopus 로고
    • Muscle and tendon morphogenesis in the avian hind limb
    • Kardon G., Muscle and tendon morphogenesis in the avian hind limb. Development 1998; 125: 4019-4032.
    • (1998) Development , vol.125 , pp. 4019-4032
    • Kardon, G.1
  • 59
    • 79960563094 scopus 로고    scopus 로고
    • Tenogenic differentiation of stem cells for tendon repair - What is the current evidence?
    • Lui PPY, Rui YF, Ni M, Chan KM., Tenogenic differentiation of stem cells for tendon repair-What is the current evidence? J Tissue Eng Regen Med 2011; 5: e144-e163.
    • (2011) J Tissue Eng Regen Med , vol.5 , pp. e144-e163
    • Lui, P.P.Y.1    Rui, Y.F.2    Ni, M.3    Chan, K.M.4
  • 62
  • 63
    • 74449085977 scopus 로고    scopus 로고
    • Integration of statistical modeling and high-content microscopy to systematically investigate cell-substrate interactions
    • Chen WLK, Likhitpanichkul M, Ho A, Simmons CA., Integration of statistical modeling and high-content microscopy to systematically investigate cell-substrate interactions. Biomaterials 2010; 31: 2489-2497.
    • (2010) Biomaterials , vol.31 , pp. 2489-2497
    • Chen, W.L.K.1    Likhitpanichkul, M.2    Ho, A.3    Simmons, C.A.4
  • 64
    • 79954424469 scopus 로고    scopus 로고
    • Design of experiments approach to engineer cell-secreted matrices for directing osteogenic differentiation
    • Decaris ML, Leach JK., Design of experiments approach to engineer cell-secreted matrices for directing osteogenic differentiation. Ann Biomed Eng 2011; 39: 1174-1185.
    • (2011) Ann Biomed Eng , vol.39 , pp. 1174-1185
    • Decaris, M.L.1    Leach, J.K.2
  • 65
    • 84857125903 scopus 로고    scopus 로고
    • Fibronectin- and collagen-mimetic ligands regulate bone marrow stromal cell chondrogenesis in three-dimensional hydrogels
    • Connelly JT, Petrie TA, García AJ, Levenston ME., Fibronectin- and collagen-mimetic ligands regulate bone marrow stromal cell chondrogenesis in three-dimensional hydrogels. Eur Cells Mater 2011; 22: 168-177.
    • (2011) Eur Cells Mater , vol.22 , pp. 168-177
    • Connelly, J.T.1    Petrie, T.A.2    García, A.J.3    Levenston, M.E.4
  • 66
    • 54949154586 scopus 로고    scopus 로고
    • Enhanced chondrogenesis of mesenchymal stem cells in collagen mimetic peptide-mediated microenvironment
    • Lee HJ, Yu C, Chansakul T, Hwang NS, Varghese S, Yu SM, Elisseeff JH., Enhanced chondrogenesis of mesenchymal stem cells in collagen mimetic peptide-mediated microenvironment. Tissue Eng Part A 2008; 11: 1843-1151.
    • (2008) Tissue Eng Part A , vol.11 , pp. 1843-1151
    • Lee, H.J.1    Yu, C.2    Chansakul, T.3    Hwang, N.S.4    Varghese, S.5    Yu, S.M.6    Elisseeff, J.H.7
  • 67
    • 0023637601 scopus 로고
    • New perspectives in cell adhesion: RGD and integrins
    • Ruoslahti E, Pierschbacher M., New perspectives in cell adhesion: RGD and integrins. Science 1987; 238: 491-497.
    • (1987) Science , vol.238 , pp. 491-497
    • Ruoslahti, E.1    Pierschbacher, M.2
  • 68
    • 20444395813 scopus 로고    scopus 로고
    • The effect of incorporating RGD adhesive peptide in polyethylene glycol diacrylate hydrogel on osteogenesis of bone marrow stromal cells
    • Yang F, Williams CG, Wang D-A, Lee H, Manson PN, Elisseeff J., The effect of incorporating RGD adhesive peptide in polyethylene glycol diacrylate hydrogel on osteogenesis of bone marrow stromal cells. Biomaterials 2005; 26: 5991-5998.
    • (2005) Biomaterials , vol.26 , pp. 5991-5998
    • Yang, F.1    Williams, C.G.2    Wang, D.-A.3    Lee, H.4    Manson, P.N.5    Elisseeff, J.6
  • 70
    • 30144445753 scopus 로고    scopus 로고
    • Function of alpha2beta1 integrin
    • Gullberg D. editor. New York, NY: Kluwer Academic
    • Zutter MM, Santoro SA., Function of alpha2beta1 integrin. In:, Gullberg D, editor. I Domains In Integrins. New York, NY: Kluwer Academic; 2003.
    • (2003) I Domains in Integrins
    • Zutter, M.M.1    Santoro, S.A.2
  • 71
    • 84924402378 scopus 로고    scopus 로고
    • Hydrogel design of experiments methodology to optimize hydrogel for iPSC-NPC culture
    • Lam J, Carmichael ST, Lowry WE, Segura T., Hydrogel design of experiments methodology to optimize hydrogel for iPSC-NPC culture. Adv Healthc Mater 2015; 4: 534-539.
    • (2015) Adv Healthc Mater , vol.4 , pp. 534-539
    • Lam, J.1    Carmichael, S.T.2    Lowry, W.E.3    Segura, T.4
  • 72
    • 79952517440 scopus 로고    scopus 로고
    • Multifactorial optimization of endothelial cell growth using modular synthetic extracellular matrices
    • Jung JP, Moyano JV, Collier JH., Multifactorial optimization of endothelial cell growth using modular synthetic extracellular matrices. Integr Biol (Camb) 2011; 3: 185-196.
    • (2011) Integr Biol (Camb) , vol.3 , pp. 185-196
    • Jung, J.P.1    Moyano, J.V.2    Collier, J.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.