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Volumn 7, Issue 2, 2012, Pages

Paracrine interactions between mesenchymal stem cells affect substrate driven differentiation toward tendon and bone phenotypes

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; CELL MARKER; COLLAGEN TYPE 1; FIBRONECTIN; LIGAND; POLYACRYLAMIDE; SMAD8 PROTEIN; MESSENGER RNA;

EID: 84857078848     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0031504     Document Type: Article
Times cited : (67)

References (50)
  • 1
    • 58149230983 scopus 로고    scopus 로고
    • The tendon-to-bone transition of the rotator cuff: a preliminary Raman spectroscopic study documenting the gradual mineralization across the insertion in rat tissue samples
    • Wopenka B, Kent A, Pasteris JD, Yoon Y, Thomopoulos S, (2008) The tendon-to-bone transition of the rotator cuff: a preliminary Raman spectroscopic study documenting the gradual mineralization across the insertion in rat tissue samples. Applied spectroscopy 62: 1285-1294.
    • (2008) Applied Spectroscopy , vol.62 , pp. 1285-1294
    • Wopenka, B.1    Kent, A.2    Pasteris, J.D.3    Yoon, Y.4    Thomopoulos, S.5
  • 2
    • 45849097198 scopus 로고    scopus 로고
    • Characterization of the structure-function relationship at the ligament-to-bone interface
    • Moffat KL, Sun WH, Pena PE, Chahine NO, Doty SB, et al. (2008) Characterization of the structure-function relationship at the ligament-to-bone interface. Proc Natl Acad Sci U S A 105: 7947-7952.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 7947-7952
    • Moffat, K.L.1    Sun, W.H.2    Pena, P.E.3    Chahine, N.O.4    Doty, S.B.5
  • 3
    • 55849128825 scopus 로고    scopus 로고
    • The clinical and structural long-term results of open repair of massive tears of the rotator cuff
    • Zumstein MA, Jost B, Hempel J, Hodler J, Gerber C, (2008) The clinical and structural long-term results of open repair of massive tears of the rotator cuff. J Bone Joint Surg Am 90: 2423-2431.
    • (2008) J Bone Joint Surg Am , vol.90 , pp. 2423-2431
    • Zumstein, M.A.1    Jost, B.2    Hempel, J.3    Hodler, J.4    Gerber, C.5
  • 4
    • 77954386001 scopus 로고    scopus 로고
    • Mesenchymal stem cells: paracrine signaling and differentiation during cutaneous wound repair
    • Hocking AM, Gibran NS, (2010) Mesenchymal stem cells: paracrine signaling and differentiation during cutaneous wound repair. Exp Cell Res 316: 2213-2219.
    • (2010) Exp Cell Res , vol.316 , pp. 2213-2219
    • Hocking, A.M.1    Gibran, N.S.2
  • 5
    • 57449109336 scopus 로고    scopus 로고
    • The Wnt modulator sFRP2 enhances mesenchymal stem cell engraftment, granulation tissue formation and myocardial repair
    • Alfaro MP, Pagni M, Vincent A, Atkinson J, Hill MF, et al. (2008) The Wnt modulator sFRP2 enhances mesenchymal stem cell engraftment, granulation tissue formation and myocardial repair. Proc Natl Acad Sci U S A 105: 18366-18371.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 18366-18371
    • Alfaro, M.P.1    Pagni, M.2    Vincent, A.3    Atkinson, J.4    Hill, M.F.5
  • 6
    • 34249277465 scopus 로고    scopus 로고
    • Enhanced epithelial gap closure and increased angiogenesis in wounds of diabetic mice treated with adult murine bone marrow stromal progenitor cells
    • Javazon EH, Keswani SG, Badillo AT, Crombleholme TM, Zoltick PW, et al. (2007) Enhanced epithelial gap closure and increased angiogenesis in wounds of diabetic mice treated with adult murine bone marrow stromal progenitor cells. Wound Repair Regen 15: 350-359.
    • (2007) Wound Repair Regen , vol.15 , pp. 350-359
    • Javazon, E.H.1    Keswani, S.G.2    Badillo, A.T.3    Crombleholme, T.M.4    Zoltick, P.W.5
  • 7
    • 33747607464 scopus 로고    scopus 로고
    • Bone marrow-derived mesenchymal stromal cells accelerate wound healing in the rat
    • McFarlin K, Gao X, Liu YB, Dulchavsky DS, Kwon D, et al. (2006) Bone marrow-derived mesenchymal stromal cells accelerate wound healing in the rat. Wound Repair Regen 14: 471-478.
    • (2006) Wound Repair Regen , vol.14 , pp. 471-478
    • McFarlin, K.1    Gao, X.2    Liu, Y.B.3    Dulchavsky, D.S.4    Kwon, D.5
  • 8
    • 70449716971 scopus 로고    scopus 로고
    • Mesenchymal stem cells induce dermal fibroblast responses to injury
    • Smith AN, Willis E, Chan VT, Muffley LA, Isik FF, et al. (2010) Mesenchymal stem cells induce dermal fibroblast responses to injury. Exp Cell Res 316: 48-54.
    • (2010) Exp Cell Res , vol.316 , pp. 48-54
    • Smith, A.N.1    Willis, E.2    Chan, V.T.3    Muffley, L.A.4    Isik, F.F.5
  • 9
    • 35348831024 scopus 로고    scopus 로고
    • Mesenchymal stem cells enhance wound healing through differentiation and angiogenesis
    • Wu Y, Chen L, Scott PG, Tredget EE, (2007) Mesenchymal stem cells enhance wound healing through differentiation and angiogenesis. Stem Cells 25: 2648-2659.
    • (2007) Stem Cells , vol.25 , pp. 2648-2659
    • Wu, Y.1    Chen, L.2    Scott, P.G.3    Tredget, E.E.4
  • 10
    • 44849121129 scopus 로고    scopus 로고
    • Paracrine factors of mesenchymal stem cells recruit macrophages and endothelial lineage cells and enhance wound healing
    • Chen L, Tredget EE, Wu PY, Wu Y, (2008) Paracrine factors of mesenchymal stem cells recruit macrophages and endothelial lineage cells and enhance wound healing. PLoS One 3: e1886.
    • (2008) PLoS One , vol.3
    • Chen, L.1    Tredget, E.E.2    Wu, P.Y.3    Wu, Y.4
  • 11
    • 67649619339 scopus 로고    scopus 로고
    • Stepwise differentiation of human embryonic stem cells promotes tendon regeneration by secreting fetal tendon matrix and differentiation factors
    • Chen X, Song XH, Yin Z, Zou XH, Wang LL, et al. (2009) Stepwise differentiation of human embryonic stem cells promotes tendon regeneration by secreting fetal tendon matrix and differentiation factors. Stem Cells 27: 1276-1287.
    • (2009) Stem Cells , vol.27 , pp. 1276-1287
    • Chen, X.1    Song, X.H.2    Yin, Z.3    Zou, X.H.4    Wang, L.L.5
  • 12
    • 0348226283 scopus 로고    scopus 로고
    • Regenerative versus reparative healing in tendon: a study of biomechanical and histological properties in fetal sheep
    • Beredjiklian PK, Favata M, Cartmell JS, Flanagan CL, Crombleholme TM, et al. (2003) Regenerative versus reparative healing in tendon: a study of biomechanical and histological properties in fetal sheep. Ann Biomed Eng 31: 1143-1152.
    • (2003) Ann Biomed Eng , vol.31 , pp. 1143-1152
    • Beredjiklian, P.K.1    Favata, M.2    Cartmell, J.S.3    Flanagan, C.L.4    Crombleholme, T.M.5
  • 13
    • 79960692785 scopus 로고    scopus 로고
    • Time kinetics of bone defect healing in response to BMP-2 and GDF-5 characterised by in vivo biomechanics
    • Wulsten D, Glatt V, Ellinghaus A, Schmidt-Bleek K, Petersen A, et al. (2011) Time kinetics of bone defect healing in response to BMP-2 and GDF-5 characterised by in vivo biomechanics. Eur Cell Mater 21: 177-192.
    • (2011) Eur Cell Mater , vol.21 , pp. 177-192
    • Wulsten, D.1    Glatt, V.2    Ellinghaus, A.3    Schmidt-Bleek, K.4    Petersen, A.5
  • 14
    • 77955776397 scopus 로고    scopus 로고
    • Biochemical and biomechanical gradients for directed bone marrow stromal cell differentiation toward tendon and bone
    • Sharma RI, Snedeker JG, (2010) Biochemical and biomechanical gradients for directed bone marrow stromal cell differentiation toward tendon and bone. Biomaterials 31: 7695-7704.
    • (2010) Biomaterials , vol.31 , pp. 7695-7704
    • Sharma, R.I.1    Snedeker, J.G.2
  • 15
    • 34247562172 scopus 로고    scopus 로고
    • The regulation of osteogenesis by ECM rigidity in MC3T3-E1 cells requires MAPK activation
    • Khatiwala CB, Peyton SR, Metzke M, Putnam AJ, (2007) The regulation of osteogenesis by ECM rigidity in MC3T3-E1 cells requires MAPK activation. J Cell Physiol 211: 661-672.
    • (2007) J Cell Physiol , vol.211 , pp. 661-672
    • Khatiwala, C.B.1    Peyton, S.R.2    Metzke, M.3    Putnam, A.J.4
  • 16
    • 33745742740 scopus 로고    scopus 로고
    • Vitronectin and collagen I differentially regulate osteogenesis in mesenchymal stem cells
    • Kundu AK, Putnam AJ, (2006) Vitronectin and collagen I differentially regulate osteogenesis in mesenchymal stem cells. Biochem Biophys Res Commun 347: 347-357.
    • (2006) Biochem Biophys Res Commun , vol.347 , pp. 347-357
    • Kundu, A.K.1    Putnam, A.J.2
  • 17
    • 0031729477 scopus 로고    scopus 로고
    • Fibronectin and integrins in cell adhesion, signaling, and morphogenesis
    • Miyamoto S, Katz BZ, Lafrenie RM, Yamada KM, (1998) Fibronectin and integrins in cell adhesion, signaling, and morphogenesis. Ann N Y Acad Sci 857: 119-129.
    • (1998) Ann N Y Acad Sci , vol.857 , pp. 119-129
    • Miyamoto, S.1    Katz, B.Z.2    Lafrenie, R.M.3    Yamada, K.M.4
  • 18
    • 38549148896 scopus 로고    scopus 로고
    • Biochemical and biophysical aspects of collagen nanostructure in the extracellular matrix
    • Kolacna L, Bakesova J, Varga F, Kostakova E, Planka L, et al. (2007) Biochemical and biophysical aspects of collagen nanostructure in the extracellular matrix. Physiol Res 56 (Suppl 1): S51-60.
    • (2007) Physiol Res , vol.56 , Issue.SUPPL. 1
    • Kolacna, L.1    Bakesova, J.2    Varga, F.3    Kostakova, E.4    Planka, L.5
  • 19
    • 62849120016 scopus 로고    scopus 로고
    • Genetic and orthopedic aspects of collagen disorders
    • Carter EM, Raggio CL, (2009) Genetic and orthopedic aspects of collagen disorders. Curr Opin Pediatr 21: 46-54.
    • (2009) Curr Opin Pediatr , vol.21 , pp. 46-54
    • Carter, E.M.1    Raggio, C.L.2
  • 20
    • 33747152561 scopus 로고    scopus 로고
    • Matrix elasticity directs stem cell lineage specification
    • Engler AJ, Sen S, Sweeney HL, Discher DE, (2006) Matrix elasticity directs stem cell lineage specification. Cell 126: 677-689.
    • (2006) Cell , vol.126 , pp. 677-689
    • Engler, A.J.1    Sen, S.2    Sweeney, H.L.3    Discher, D.E.4
  • 21
    • 34548580322 scopus 로고    scopus 로고
    • Bone morphogenetic protein signaling suppresses tumorigenesis at gastric epithelial transition zones in mice
    • Bleuming SA, He XC, Kodach LL, Hardwick JC, Koopman FA, et al. (2007) Bone morphogenetic protein signaling suppresses tumorigenesis at gastric epithelial transition zones in mice. Cancer Res 67: 8149-8155.
    • (2007) Cancer Res , vol.67 , pp. 8149-8155
    • Bleuming, S.A.1    He, X.C.2    Kodach, L.L.3    Hardwick, J.C.4    Koopman, F.A.5
  • 22
    • 33645529161 scopus 로고    scopus 로고
    • Neotendon formation induced by manipulation of the Smad8 signalling pathway in mesenchymal stem cells
    • Hoffmann A, Pelled G, Turgeman G, Eberle P, Zilberman Y, et al. (2006) Neotendon formation induced by manipulation of the Smad8 signalling pathway in mesenchymal stem cells. J Clin Invest 116: 940-952.
    • (2006) J Clin Invest , vol.116 , pp. 940-952
    • Hoffmann, A.1    Pelled, G.2    Turgeman, G.3    Eberle, P.4    Zilberman, Y.5
  • 23
    • 77958150072 scopus 로고    scopus 로고
    • Mesenchymal stem cell-dependent formation of heterotopic tendon-bone insertions (osteotendinous junctions)
    • Shahab-Osterloh S, Witte F, Hoffmann A, Winkel A, Laggies S, et al. (2010) Mesenchymal stem cell-dependent formation of heterotopic tendon-bone insertions (osteotendinous junctions). Stem Cells 28: 1590-1601.
    • (2010) Stem Cells , vol.28 , pp. 1590-1601
    • Shahab-Osterloh, S.1    Witte, F.2    Hoffmann, A.3    Winkel, A.4    Laggies, S.5
  • 24
    • 27944497333 scopus 로고    scopus 로고
    • Tissue cells feel and respond to the stiffness of their substrate
    • Discher DE, Janmey P, Wang YL, (2005) Tissue cells feel and respond to the stiffness of their substrate. Science 310: 1139-1143.
    • (2005) Science , vol.310 , pp. 1139-1143
    • Discher, D.E.1    Janmey, P.2    Wang, Y.L.3
  • 25
    • 57049152474 scopus 로고    scopus 로고
    • Directing osteogenic and myogenic differentiation of MSCs: interplay of stiffness and adhesive ligand presentation
    • Rowlands AS, George PA, Cooper-White JJ, (2008) Directing osteogenic and myogenic differentiation of MSCs: interplay of stiffness and adhesive ligand presentation. Am J Physiol Cell Physiol 295: C1037-1044.
    • (2008) Am J Physiol Cell Physiol , vol.295
    • Rowlands, A.S.1    George, P.A.2    Cooper-White, J.J.3
  • 26
    • 79951874643 scopus 로고    scopus 로고
    • Adipose progenitor cells increase fibronectin matrix strain and unfolding in breast tumors
    • Chandler EM, Saunders MP, Yoon CJ, Gourdon D, Fischbach C, (2011) Adipose progenitor cells increase fibronectin matrix strain and unfolding in breast tumors. Phys Biol 8: 015008.
    • (2011) Phys Biol , vol.8 , pp. 015008
    • Chandler, E.M.1    Saunders, M.P.2    Yoon, C.J.3    Gourdon, D.4    Fischbach, C.5
  • 30
    • 77955281178 scopus 로고    scopus 로고
    • Modulating osteogenesis of mesenchymal stem cells by modifying growth factor availability
    • Huang Z, Ren PG, Ma T, Smith RL, Goodman SB, (2010) Modulating osteogenesis of mesenchymal stem cells by modifying growth factor availability. Cytokine 51: 305-310.
    • (2010) Cytokine , vol.51 , pp. 305-310
    • Huang, Z.1    Ren, P.G.2    Ma, T.3    Smith, R.L.4    Goodman, S.B.5
  • 31
    • 79959345857 scopus 로고    scopus 로고
    • Integrin activation and internalization on soft ECM as a mechanism of induction of stem cell differentiation by ECM elasticity
    • Du J, Chen X, Liang X, Zhang G, Xu J, et al. (2011) Integrin activation and internalization on soft ECM as a mechanism of induction of stem cell differentiation by ECM elasticity. Proc Natl Acad Sci U S A 108: 9466-9471.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 9466-9471
    • Du, J.1    Chen, X.2    Liang, X.3    Zhang, G.4    Xu, J.5
  • 32
    • 39049131134 scopus 로고    scopus 로고
    • BMPs promote proliferation and migration of endothelial cells via stimulation of VEGF-A/VEGFR2 and angiopoietin-1/Tie2 signalling
    • Suzuki Y, Montagne K, Nishihara A, Watabe T, Miyazono K, (2008) BMPs promote proliferation and migration of endothelial cells via stimulation of VEGF-A/VEGFR2 and angiopoietin-1/Tie2 signalling. J Biochem 143: 199-206.
    • (2008) J Biochem , vol.143 , pp. 199-206
    • Suzuki, Y.1    Montagne, K.2    Nishihara, A.3    Watabe, T.4    Miyazono, K.5
  • 33
    • 38049055683 scopus 로고    scopus 로고
    • Regulation of bone morphogenetic protein signalling in human pulmonary vascular development
    • Southwood M, Jeffery TK, Yang X, Upton PD, Hall SM, et al. (2008) Regulation of bone morphogenetic protein signalling in human pulmonary vascular development. J Pathol 214: 85-95.
    • (2008) J Pathol , vol.214 , pp. 85-95
    • Southwood, M.1    Jeffery, T.K.2    Yang, X.3    Upton, P.D.4    Hall, S.M.5
  • 34
    • 68249154734 scopus 로고    scopus 로고
    • Recombinant human bone morphogenetic protein-2 promotes the proliferation of mesenchymal stem cells in vivo and in vitro
    • Liu SB, Hu PZ, Hou Y, Li P, Cao W, et al. (2009) Recombinant human bone morphogenetic protein-2 promotes the proliferation of mesenchymal stem cells in vivo and in vitro. Chin Med J (Engl) 122: 839-843.
    • (2009) Chin Med J (Engl) , vol.122 , pp. 839-843
    • Liu, S.B.1    Hu, P.Z.2    Hou, Y.3    Li, P.4    Cao, W.5
  • 35
    • 34548444264 scopus 로고    scopus 로고
    • Bone morphogenetic proteins and their receptors in the eye
    • Wordinger RJ, Clark AF, (2007) Bone morphogenetic proteins and their receptors in the eye. Exp Biol Med (Maywood) 232: 979-992.
    • (2007) Exp Biol Med (Maywood) , vol.232 , pp. 979-992
    • Wordinger, R.J.1    Clark, A.F.2
  • 36
    • 34247638937 scopus 로고    scopus 로고
    • Tethered epidermal growth factor provides a survival advantage to mesenchymal stem cells
    • Fan VH, Tamama K, Au A, Littrell R, Richardson LB, et al. (2007) Tethered epidermal growth factor provides a survival advantage to mesenchymal stem cells. Stem Cells 25: 1241-1251.
    • (2007) Stem Cells , vol.25 , pp. 1241-1251
    • Fan, V.H.1    Tamama, K.2    Au, A.3    Littrell, R.4    Richardson, L.B.5
  • 37
    • 0344912596 scopus 로고    scopus 로고
    • Cell locomotion and focal adhesions are regulated by substrate flexibility
    • Pelham RJ Jr, Wang Y, (1997) Cell locomotion and focal adhesions are regulated by substrate flexibility. Proc Natl Acad Sci U S A 94: 13661-13665.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 13661-13665
    • Pelham Jr., R.J.1    Wang, Y.2
  • 38
    • 0035941075 scopus 로고    scopus 로고
    • Taking cell-matrix adhesions to the third dimension
    • Cukierman E, Pankov R, Stevens DR, Yamada KM, (2001) Taking cell-matrix adhesions to the third dimension. Science 294: 1708-1712.
    • (2001) Science , vol.294 , pp. 1708-1712
    • Cukierman, E.1    Pankov, R.2    Stevens, D.R.3    Yamada, K.M.4
  • 39
    • 0037167649 scopus 로고    scopus 로고
    • Tissue engineering of functional trileaflet heart valves from human marrow stromal cells
    • Hoerstrup SP, Kadner A, Melnitchouk S, Trojan A, Eid K, et al. (2002) Tissue engineering of functional trileaflet heart valves from human marrow stromal cells. Circulation 106: I143-150.
    • (2002) Circulation , vol.106
    • Hoerstrup, S.P.1    Kadner, A.2    Melnitchouk, S.3    Trojan, A.4    Eid, K.5
  • 40
    • 67349168122 scopus 로고    scopus 로고
    • In vitro osteogenesis assays: influence of the primary cell source on alkaline phosphatase activity and mineralization
    • Hoemann CD, El-Gabalawy H, McKee MD, (2009) In vitro osteogenesis assays: influence of the primary cell source on alkaline phosphatase activity and mineralization. Pathol Biol (Paris) 57: 318-323.
    • (2009) Pathol Biol (Paris) , vol.57 , pp. 318-323
    • Hoemann, C.D.1    El-Gabalawy, H.2    McKee, M.D.3
  • 41
    • 12244296438 scopus 로고    scopus 로고
    • Changes in Runx2/Cbfa1 expression and activity during osteoblastic differentiation of human bone marrow stromal cells
    • Shui C, Spelsberg TC, Riggs BL, Khosla S, (2003) Changes in Runx2/Cbfa1 expression and activity during osteoblastic differentiation of human bone marrow stromal cells. J Bone Miner Res 18: 213-221.
    • (2003) J Bone Miner Res , vol.18 , pp. 213-221
    • Shui, C.1    Spelsberg, T.C.2    Riggs, B.L.3    Khosla, S.4
  • 42
    • 0037441529 scopus 로고    scopus 로고
    • Regulation of the osteoblast-specific transcription factor, Runx2: responsiveness to multiple signal transduction pathways
    • Franceschi RT, Xiao G, (2003) Regulation of the osteoblast-specific transcription factor, Runx2: responsiveness to multiple signal transduction pathways. J Cell Biochem 88: 446-454.
    • (2003) J Cell Biochem , vol.88 , pp. 446-454
    • Franceschi, R.T.1    Xiao, G.2
  • 43
    • 67650091219 scopus 로고    scopus 로고
    • Osteogenic differentiation of mesenchymal stem cells in multiple myeloma: identification of potential therapeutic targets
    • Giuliani N, Mangoni M, Rizzoli V, (2009) Osteogenic differentiation of mesenchymal stem cells in multiple myeloma: identification of potential therapeutic targets. Exp Hematol 37: 879-886.
    • (2009) Exp Hematol , vol.37 , pp. 879-886
    • Giuliani, N.1    Mangoni, M.2    Rizzoli, V.3
  • 44
    • 0242417166 scopus 로고    scopus 로고
    • A somitic compartment of tendon progenitors
    • Brent AE, Schweitzer R, Tabin CJ, (2003) A somitic compartment of tendon progenitors. Cell 113: 235-248.
    • (2003) Cell , vol.113 , pp. 235-248
    • Brent, A.E.1    Schweitzer, R.2    Tabin, C.J.3
  • 45
    • 56449111180 scopus 로고    scopus 로고
    • Tendon repair through stem cell intervention: cellular and molecular approaches
    • Bullough R, Finnigan T, Kay A, Maffulli N, Forsyth NR, (2008) Tendon repair through stem cell intervention: cellular and molecular approaches. Disabil Rehabil 30: 1746-1751.
    • (2008) Disabil Rehabil , vol.30 , pp. 1746-1751
    • Bullough, R.1    Finnigan, T.2    Kay, A.3    Maffulli, N.4    Forsyth, N.R.5
  • 46
    • 65549114268 scopus 로고    scopus 로고
    • Horse bone marrow mesenchymal stem cells express embryo stem cell markers and show the ability for tenogenic differentiation by in vitro exposure to BMP-12
    • Violini S, Ramelli P, Pisani LF, Gorni C, Mariani P, (2009) Horse bone marrow mesenchymal stem cells express embryo stem cell markers and show the ability for tenogenic differentiation by in vitro exposure to BMP-12. BMC Cell Biol 10: 29.
    • (2009) BMC Cell Biol , vol.10 , pp. 29
    • Violini, S.1    Ramelli, P.2    Pisani, L.F.3    Gorni, C.4    Mariani, P.5
  • 47
    • 11844286305 scopus 로고    scopus 로고
    • Tenomodulin is necessary for tenocyte proliferation and tendon maturation
    • Docheva D, Hunziker EB, Fassler R, Brandau O, (2005) Tenomodulin is necessary for tenocyte proliferation and tendon maturation. Mol Cell Biol 25: 699-705.
    • (2005) Mol Cell Biol , vol.25 , pp. 699-705
    • Docheva, D.1    Hunziker, E.B.2    Fassler, R.3    Brandau, O.4
  • 48
    • 33748765254 scopus 로고    scopus 로고
    • Scleraxis positively regulates the expression of tenomodulin, a differentiation marker of tenocytes
    • Shukunami C, Takimoto A, Oro M, Hiraki Y, (2006) Scleraxis positively regulates the expression of tenomodulin, a differentiation marker of tenocytes. Dev Biol 298: 234-247.
    • (2006) Dev Biol , vol.298 , pp. 234-247
    • Shukunami, C.1    Takimoto, A.2    Oro, M.3    Hiraki, Y.4
  • 49
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
    • Livak KJ, Schmittgen TD, (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25: 402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 50
    • 77957071242 scopus 로고    scopus 로고
    • ERK 1/2 and PI-3 kinase pathways as a potential mechanism of ghrelin action on cell proliferation and apoptosis in the porcine ovarian follicular cells
    • Rak-Mardyla A, Gregoraszczuk EL, (2010) ERK 1/2 and PI-3 kinase pathways as a potential mechanism of ghrelin action on cell proliferation and apoptosis in the porcine ovarian follicular cells. J Physiol Pharmacol 61: 451-458.
    • (2010) J Physiol Pharmacol , vol.61 , pp. 451-458
    • Rak-Mardyla, A.1    Gregoraszczuk, E.L.2


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