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Volumn 101, Issue , 2016, Pages 27-39

SGLT2 inhibitors

Author keywords

[No Author keywords available]

Indexed keywords

CANAGLIFLOZIN; DAPAGLIFLOZIN; EMPAGLIFLOZIN; GLIMEPIRIDE; GLUCOSE; HEMOGLOBIN; INSULIN; LINAGLIPTIN; METFORMIN; PIOGLITAZONE; SITAGLIPTIN; SODIUM GLUCOSE COTRANSPORTER 2 INHIBITOR; SULFONYLUREA; AGENTS AFFECTING WATER, MOLECULE OR ION TRANSPORT; ANTIDIABETIC AGENT; SLC5A2 PROTEIN, HUMAN; SODIUM GLUCOSE COTRANSPORTER 2;

EID: 84957431946     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2015.09.005     Document Type: Note
Times cited : (32)

References (79)
  • 1
    • 84962476809 scopus 로고    scopus 로고
    • Life years lost and lifetime health care expenditures associated with diabetes in the U.S., national health interview survey, 1997-2000
    • M.Y. Leung, L.M. Pollack, G.A. Colditz, and S.H. Chang Life years lost and lifetime health care expenditures associated with diabetes in the U.S., national health interview survey, 1997-2000 Diabetes Care 38 3 2015 460 468
    • (2015) Diabetes Care , vol.38 , Issue.3 , pp. 460-468
    • Leung, M.Y.1    Pollack, L.M.2    Colditz, G.A.3    Chang, S.H.4
  • 3
    • 84919999219 scopus 로고    scopus 로고
    • Management of hyperglycemia in type 2 diabetes, a patient-centered approach: Update to a position statement of the American Diabetes Association and the European Association for the Study of Diabetes
    • S.E. Inzucchi, R.M. Bergenstal, J.B. Buse, M. Diamant, E. Ferrannini, M. Nauck, and et al. Management of hyperglycemia in type 2 diabetes, a patient-centered approach: update to a position statement of the American Diabetes Association and the European Association for the Study of Diabetes Diabetes Care 38 1 2015 140 149
    • (2015) Diabetes Care , vol.38 , Issue.1 , pp. 140-149
    • Inzucchi, S.E.1    Bergenstal, R.M.2    Buse, J.B.3    Diamant, M.4    Ferrannini, E.5    Nauck, M.6
  • 4
    • 84893766447 scopus 로고    scopus 로고
    • SGLT2 inhibitors to control glycemia in type 2 diabetes mellitus: A new approach to an old problem
    • S.A. Jabbour SGLT2 inhibitors to control glycemia in type 2 diabetes mellitus: a new approach to an old problem Postgrad. Med. 126 1 2014 111 117
    • (2014) Postgrad. Med. , vol.126 , Issue.1 , pp. 111-117
    • Jabbour, S.A.1
  • 5
    • 84914145031 scopus 로고    scopus 로고
    • Sodium glucose cotransporter 2 inhibitors
    • J.R. White Sodium glucose cotransporter 2 inhibitors Med. Clin. North Am. 99 1 2015 131 143
    • (2015) Med. Clin. North Am. , vol.99 , Issue.1 , pp. 131-143
    • White, J.R.1
  • 6
    • 84930841315 scopus 로고    scopus 로고
    • American association of clinical endocrinologists and American college of endocrinology - Clinical practice guidelines for developing a diabetes mellitus comprehensive care plan - 2015
    • Y. Handelsman, Z.T. Bloomgarden, G. Grunberger, G. Umpierrez, R.S. Zimmerman, T.S. Bailey, and et al. American association of clinical endocrinologists and American college of endocrinology - clinical practice guidelines for developing a diabetes mellitus comprehensive care plan - 2015 Endocr. Pract. 21 2015 1 87
    • (2015) Endocr. Pract. , vol.21 , pp. 1-87
    • Handelsman, Y.1    Bloomgarden, Z.T.2    Grunberger, G.3    Umpierrez, G.4    Zimmerman, R.S.5    Bailey, T.S.6
  • 7
    • 47149118686 scopus 로고    scopus 로고
    • Sodium glucose co-transporter 2 inhibitors: Blocking renal tubular reabsorption of glucose to improve glycaemic control in patients with diabetes
    • S.A. Jabbour, and B.J. Goldstein Sodium glucose co-transporter 2 inhibitors: blocking renal tubular reabsorption of glucose to improve glycaemic control in patients with diabetes Int. J. Clin. Pract. 62 8 2008 1279 1284
    • (2008) Int. J. Clin. Pract. , vol.62 , Issue.8 , pp. 1279-1284
    • Jabbour, S.A.1    Goldstein, B.J.2
  • 8
    • 84923527667 scopus 로고    scopus 로고
    • Probing SGLT2 as a therapeutic target for diabetes: Basic physiology and consequences
    • L.A. Gallo, E.M. Wright, and V. Vallon Probing SGLT2 as a therapeutic target for diabetes: basic physiology and consequences Diab. Vasc. Dis. Res. 12 2 2015 78 89
    • (2015) Diab. Vasc. Dis. Res. , vol.12 , Issue.2 , pp. 78-89
    • Gallo, L.A.1    Wright, E.M.2    Vallon, V.3
  • 9
    • 84910077533 scopus 로고    scopus 로고
    • The potential role of sodium glucose co-transporter 2 inhibitors in combination therapy for type 2 diabetes mellitus
    • R. Lajara The potential role of sodium glucose co-transporter 2 inhibitors in combination therapy for type 2 diabetes mellitus Expert Opin. Pharmacother. 15 17 2014 2565 2585
    • (2014) Expert Opin. Pharmacother. , vol.15 , Issue.17 , pp. 2565-2585
    • Lajara, R.1
  • 10
    • 0034520399 scopus 로고    scopus 로고
    • Physiology of glucose homeostasis
    • J.E. Gerich Physiology of glucose homeostasis Diabetes Obes. Metab. 2 6 2000 345 350
    • (2000) Diabetes Obes. Metab. , vol.2 , Issue.6 , pp. 345-350
    • Gerich, J.E.1
  • 11
    • 79958266386 scopus 로고    scopus 로고
    • Glucose handling by the kidney
    • A. Mather, and C. Pollock Glucose handling by the kidney Kidney Int. Suppl. 120 2011 S1 S6
    • (2011) Kidney Int. Suppl. , Issue.120 , pp. S1-S6
    • Mather, A.1    Pollock, C.2
  • 12
    • 76249133903 scopus 로고    scopus 로고
    • Role of the kidney in normal glucose homeostasis and in the hyperglycaemia of diabetes mellitus: Therapeutic implications
    • J.E. Gerich Role of the kidney in normal glucose homeostasis and in the hyperglycaemia of diabetes mellitus: therapeutic implications Diabet. Med. 27 2 2010 136 142
    • (2010) Diabet. Med. , vol.27 , Issue.2 , pp. 136-142
    • Gerich, J.E.1
  • 13
    • 0036084280 scopus 로고    scopus 로고
    • Role of human liver, kidney, and skeletal muscle in postprandial glucose homeostasis
    • C. Meyer, J.M. Dostou, S.L. Welle, and J.E. Gerich Role of human liver, kidney, and skeletal muscle in postprandial glucose homeostasis Am. J. Physiol. Endocrinol. Metab. 282 2 2002 E419 E427
    • (2002) Am. J. Physiol. Endocrinol. Metab. , vol.282 , Issue.2 , pp. E419-E427
    • Meyer, C.1    Dostou, J.M.2    Welle, S.L.3    Gerich, J.E.4
  • 16
    • 80052362968 scopus 로고    scopus 로고
    • Role of sodium-glucose cotransporter 2 (SGLT 2) inhibitors in the treatment of type 2 diabetes
    • M.A. Abdul-ghani, L. Norton, and R.A. Defronzo Role of sodium-glucose cotransporter 2 (SGLT 2) inhibitors in the treatment of type 2 diabetes Endocr. Rev. 32 4 2011 515 531
    • (2011) Endocr. Rev. , vol.32 , Issue.4 , pp. 515-531
    • Abdul-Ghani, M.A.1    Norton, L.2    Defronzo, R.A.3
  • 17
    • 84929354073 scopus 로고    scopus 로고
    • Sodium-glucose cotransport inhibitors: Mechanisms, metabolic effects and implications for the treatment of diabetic patients with chronic kidney disease
    • G. Vlotides, and P.R. Mertens Sodium-glucose cotransport inhibitors: mechanisms, metabolic effects and implications for the treatment of diabetic patients with chronic kidney disease Nephrol. Dial. Transplant. 2014
    • (2014) Nephrol. Dial. Transplant.
    • Vlotides, G.1    Mertens, P.R.2
  • 18
    • 75149196250 scopus 로고    scopus 로고
    • Sodium glucose cotransporter 2 inhibitors as a new treatment for diabetes mellitus
    • S. Nair, and J.P. Wilding Sodium glucose cotransporter 2 inhibitors as a new treatment for diabetes mellitus J. Clin. Endocrinol. Metab. 95 1 2010 34 42
    • (2010) J. Clin. Endocrinol. Metab. , vol.95 , Issue.1 , pp. 34-42
    • Nair, S.1    Wilding, J.P.2
  • 19
    • 78651349221 scopus 로고    scopus 로고
    • Biology of human sodium glucose transporters
    • E.M. Wright, D.D. Loo, and B.A. Hirayama Biology of human sodium glucose transporters Physiol. Rev. 91 2 2011 733 794
    • (2011) Physiol. Rev. , vol.91 , Issue.2 , pp. 733-794
    • Wright, E.M.1    Loo, D.D.2    Hirayama, B.A.3
  • 20
    • 83655193529 scopus 로고    scopus 로고
    • The role of the kidneys in glucose homeostasis: A new path towards normalizing glycaemia
    • R.A. Defronzo, J.A. Davidson, and S. Del Prato The role of the kidneys in glucose homeostasis: a new path towards normalizing glycaemia Diabetes Obes. Metab. 14 1 2012 5 14
    • (2012) Diabetes Obes. Metab. , vol.14 , Issue.1 , pp. 5-14
    • Defronzo, R.A.1    Davidson, J.A.2    Del Prato, S.3
  • 21
    • 33644688031 scopus 로고    scopus 로고
    • Glucose transporters in human renal proximal tubular cells isolated from the urine of patients with non-insulin-dependent diabetes
    • H. Rahmoune, P.W. Thompson, J.M. Ward, C.D. Smith, G. Hong, and J. Brown Glucose transporters in human renal proximal tubular cells isolated from the urine of patients with non-insulin-dependent diabetes Diabetes 54 12 2005 3427 3434
    • (2005) Diabetes , vol.54 , Issue.12 , pp. 3427-3434
    • Rahmoune, H.1    Thompson, P.W.2    Ward, J.M.3    Smith, C.D.4    Hong, G.5    Brown, J.6
  • 22
    • 80052819282 scopus 로고    scopus 로고
    • Development and potential role of type-2 sodium-glucose transporter inhibitors for management of type 2 diabetes
    • T.C. Hardman, and S.W. Dubrey Development and potential role of type-2 sodium-glucose transporter inhibitors for management of type 2 diabetes Diabetes Ther. 2 3 2011 133 145
    • (2011) Diabetes Ther. , vol.2 , Issue.3 , pp. 133-145
    • Hardman, T.C.1    Dubrey, S.W.2
  • 23
    • 8544226262 scopus 로고    scopus 로고
    • Abnormal renal, hepatic, and muscle glucose metabolism following glucose ingestion in type 2 diabetes
    • C. Meyer, H.J. Woerle, J.M. Dostou, S.L. Welle, and J.E. Gerich Abnormal renal, hepatic, and muscle glucose metabolism following glucose ingestion in type 2 diabetes Am. J. Physiol. Endocrinol. Metab. 287 6 2004 E1049 E1056
    • (2004) Am. J. Physiol. Endocrinol. Metab. , vol.287 , Issue.6 , pp. E1049-E1056
    • Meyer, C.1    Woerle, H.J.2    Dostou, J.M.3    Welle, S.L.4    Gerich, J.E.5
  • 24
    • 84928911112 scopus 로고    scopus 로고
    • Sodium-glucose co-transporter 2 (SGLT2) inhibitors: A growing class of antidiabetic agents
    • E.M. Vivian Sodium-glucose co-transporter 2 (SGLT2) inhibitors: a growing class of antidiabetic agents Drugs Context 3 2014 212264
    • (2014) Drugs Context , vol.3 , pp. 212264
    • Vivian, E.M.1
  • 25
    • 64749094872 scopus 로고
    • Effect of diabetes and insulin of the maximum capacity of the renal tubules to reabsorb glucose
    • S.J. Farber, E.Y. Berger, and D.P. Earle Effect of diabetes and insulin of the maximum capacity of the renal tubules to reabsorb glucose J. Clin. Invest. 30 2 1951 125 129
    • (1951) J. Clin. Invest. , vol.30 , Issue.2 , pp. 125-129
    • Farber, S.J.1    Berger, E.Y.2    Earle, D.P.3
  • 26
    • 84921788614 scopus 로고    scopus 로고
    • Use of systems pharmacology modeling to elucidate the operating characteristics of SGLT1 and SGLT2 in renal glucose reabsorption in humans
    • Y. Lu, S.C. Griffen, D.W. Boulton, and T.A. Leil Use of systems pharmacology modeling to elucidate the operating characteristics of SGLT1 and SGLT2 in renal glucose reabsorption in humans Front. Pharmacol. 5 2014 274
    • (2014) Front. Pharmacol. , vol.5 , pp. 274
    • Lu, Y.1    Griffen, S.C.2    Boulton, D.W.3    Leil, T.A.4
  • 27
    • 84865479822 scopus 로고    scopus 로고
    • Why Do SGLT2 inhibitors inhibit only 30-50% of renal glucose reabsorption in humans?
    • J.J. Liu, T. Lee, and R.A. Defronzo Why Do SGLT2 inhibitors inhibit only 30-50% of renal glucose reabsorption in humans? Diabetes 61 9 2012 2199 2204
    • (2012) Diabetes , vol.61 , Issue.9 , pp. 2199-2204
    • Liu, J.J.1    Lee, T.2    Defronzo, R.A.3
  • 28
    • 84921374064 scopus 로고    scopus 로고
    • The mechanisms and therapeutic potential of SGLT2 inhibitors in diabetes mellitus
    • V. Vallon The mechanisms and therapeutic potential of SGLT2 inhibitors in diabetes mellitus Annu. Rev. Med. 66 2015 255 270
    • (2015) Annu. Rev. Med. , vol.66 , pp. 255-270
    • Vallon, V.1
  • 29
    • 84929676338 scopus 로고    scopus 로고
    • Efficacy and safety of canagliflozin in subjects with type 2 diabetes: Systematic review and meta-analysis
    • OCTOBET 10
    • X.P. Yang, D. Lai, X.Y. Zhong, H.P. Shen, and Y.L. Huang Efficacy and safety of canagliflozin in subjects with type 2 diabetes: systematic review and meta-analysis Eur. J. Clin. Pharmacol. 70 Octobet (10) 2014 1149 1158
    • (2014) Eur. J. Clin. Pharmacol. , vol.70 , pp. 1149-1158
    • Yang, X.P.1    Lai, D.2    Zhong, X.Y.3    Shen, H.P.4    Huang, Y.L.5
  • 30
    • 84957440270 scopus 로고    scopus 로고
    • (canagliflozin) tablets, for oral use [package insert]. Janssen Pharmaceuticals, Titusville, NJ; 2014
    • INVOKANA™ (canagliflozin) tablets, for oral use [package insert]. Janssen Pharmaceuticals, Titusville, NJ; 2014.
    • INVOKANA™
  • 31
    • 84863610946 scopus 로고    scopus 로고
    • Effect of canagliflozin, a sodium glucose co-transporter 2 (SGLT2) inhibitor, on bacteriuria and urinary tract infection in subjects with type 2 diabetes enrolled in a 12-week, phase 2 study
    • L.E. Nicolle, G. Capuano, K. Ways, and K. Usiskin Effect of canagliflozin, a sodium glucose co-transporter 2 (SGLT2) inhibitor, on bacteriuria and urinary tract infection in subjects with type 2 diabetes enrolled in a 12-week, phase 2 study Curr. Med. Res. Opin. 28 2012 1167 1171
    • (2012) Curr. Med. Res. Opin. , vol.28 , pp. 1167-1171
    • Nicolle, L.E.1    Capuano, G.2    Ways, K.3    Usiskin, K.4
  • 32
    • 84904723621 scopus 로고    scopus 로고
    • Safety of canagliflozin in patients with type 2 diabetes
    • N. Mikhail Safety of canagliflozin in patients with type 2 diabetes Curr. Drug Saf. 9 2 2014 127 132
    • (2014) Curr. Drug Saf. , vol.9 , Issue.2 , pp. 127-132
    • Mikhail, N.1
  • 33
    • 84897019959 scopus 로고    scopus 로고
    • Urinary tract infection in randomized phase III studies of canagliflozin, a sodium glucose co-transporter 2 inhibitor
    • L.E. Nicolle, G. Capuano, A. Fung, and K. Usiskin Urinary tract infection in randomized phase III studies of canagliflozin, a sodium glucose co-transporter 2 inhibitor Postgrad. Med. 126 2014 7 17
    • (2014) Postgrad. Med. , vol.126 , pp. 7-17
    • Nicolle, L.E.1    Capuano, G.2    Fung, A.3    Usiskin, K.4
  • 34
    • 84918559672 scopus 로고    scopus 로고
    • A review of the efficacy and safety of canagliflozin in elderly patients with type 2 diabetes
    • L.K. Elmore, S. Baggett, J.A. Kyle, and J.W. Skelley A review of the efficacy and safety of canagliflozin in elderly patients with type 2 diabetes Consult. Pharm. 29 2014 335 346
    • (2014) Consult. Pharm. , vol.29 , pp. 335-346
    • Elmore, L.K.1    Baggett, S.2    Kyle, J.A.3    Skelley, J.W.4
  • 35
    • 84899960517 scopus 로고    scopus 로고
    • Efficacy and safety of canagliflozin compared with placebo in older patients with type 2 diabetes mellitus: A pooled analysis of clinical studies
    • A. Sinclair, B. Bode, S. Harris, U. Vijapurkar, C. Mayer, A. Fung, and et al. Efficacy and safety of canagliflozin compared with placebo in older patients with type 2 diabetes mellitus: a pooled analysis of clinical studies BMC Endocr. Disord. 14 2014 37
    • (2014) BMC Endocr. Disord. , vol.14 , pp. 37
    • Sinclair, A.1    Bode, B.2    Harris, S.3    Vijapurkar, U.4    Mayer, C.5    Fung, A.6
  • 37
    • 84940110139 scopus 로고    scopus 로고
    • Canagliflozin provides durable glycemic improvements and body weight reduction over 104 weeks versus glimepiride in patients with type 2 diabetes on metformin: A randomized, double-blind, phase 3 study
    • MARCH 3
    • L.A. Leiter, K.-H. Yoon, P. Arias, G. Langslet, J. Xie, D.A. Balis, and et al. Canagliflozin provides durable glycemic improvements and body weight reduction over 104 weeks versus glimepiride in patients with type 2 diabetes on metformin: a randomized, double-blind, phase 3 study Diabetes Care 38 March (3) 2015 355 364
    • (2015) Diabetes Care , vol.38 , pp. 355-364
    • Leiter, L.A.1    Yoon, K.-H.2    Arias, P.3    Langslet, G.4    Xie, J.5    Balis, D.A.6
  • 38
    • 84964240560 scopus 로고    scopus 로고
    • Long-term efficacy and safety of canagliflozin over 104 weeks in patients aged 55-80 years with type 2 diabetes
    • MARCH 3
    • B. Bode, K. Stenlöf, S. Harris, D. Sullivan, A. Fung, K. Usiskin, and et al. Long-term efficacy and safety of canagliflozin over 104 weeks in patients aged 55-80 years with type 2 diabetes Diabetes Obes. Metab. 17 March (3) 2015 294 303
    • (2015) Diabetes Obes. Metab. , vol.17 , pp. 294-303
    • Bode, B.1    Stenlöf, K.2    Harris, S.3    Sullivan, D.4    Fung, A.5    Usiskin, K.6
  • 39
    • 84880924263 scopus 로고    scopus 로고
    • Rationale, design, and baseline characteristics of the CANagliflozin cardioVascular assessment study (CANVAS) - A randomized placebo-controlled trial
    • B. Neal, V. Perkovic, Z. de, D. eeuw, K.W. Mahaffey, G. Fulcher, P. Stein, and et al. Rationale, design, and baseline characteristics of the CANagliflozin cardioVascular assessment study (CANVAS) - a randomized placebo-controlled trial Am. Heart J. 166 2013 217 223.e11
    • (2013) Am. Heart J. , vol.166 , pp. 217-223e11
    • Neal, B.1    Perkovic, V.2    De, Z.3    Eeuw, D.4    Mahaffey, K.W.5    Fulcher, G.6    Stein, P.7
  • 40
    • 84927744959 scopus 로고    scopus 로고
    • Efficacy, safety and regulatory status of SGLT2 inhibitors: Focus on canagliflozin
    • NOVEMBER 11
    • B.E. Haas, N.P. ckstien, V.M. feifer, and P. ayer Efficacy, safety and regulatory status of SGLT2 inhibitors: focus on canagliflozin Nutr. Diabetes 4 November (11) 2014 e143
    • (2014) Nutr. Diabetes , vol.4 , pp. e143
    • Haas, B.E.1    Ckstien, N.P.2    Feifer, V.M.3    Ayer, P.4
  • 41
    • 84874291673 scopus 로고    scopus 로고
    • Efficacy and safety of canagliflozin monotherapy in subjects with type 2 diabetes mellitus inadequately controlled with diet and exercise
    • K. Stenlöf, W.T. Cefalu, K.A. Kim, M. Alba, K. Usiskin, C. Tong, and et al. Efficacy and safety of canagliflozin monotherapy in subjects with type 2 diabetes mellitus inadequately controlled with diet and exercise Diabetes Obes. Metab. 15 4 2013 372 382
    • (2013) Diabetes Obes. Metab. , vol.15 , Issue.4 , pp. 372-382
    • Stenlöf, K.1    Cefalu, W.T.2    Kim, K.A.3    Alba, M.4    Usiskin, K.5    Tong, C.6
  • 42
    • 84904207974 scopus 로고    scopus 로고
    • Efficacy and safety of canagliflozin monotherapy in Japanese patients with type 2 diabetes inadequately controlled with diet and exercise: A 24-week, randomized, double-blind, placebo-controlled. Phase III study
    • N. Inagaki, K. Kondo, T. Yoshinari, N. Takahashi, Y. Susuta, and H. Kuki Efficacy and safety of canagliflozin monotherapy in Japanese patients with type 2 diabetes inadequately controlled with diet and exercise: a 24-week, randomized, double-blind, placebo-controlled. Phase III study Expert Opin. Pharmacother. 15 11 2014 1501 1515
    • (2014) Expert Opin. Pharmacother. , vol.15 , Issue.11 , pp. 1501-1515
    • Inagaki, N.1    Kondo, K.2    Yoshinari, T.3    Takahashi, N.4    Susuta, Y.5    Kuki, H.6
  • 43
    • 84861781220 scopus 로고    scopus 로고
    • Effects of canagliflozin, a sodium-glucose cotransporter 2 inhibitor, as add-on to metformin in subjects with type 2 diabetes
    • JUNE 6
    • J. Rosenstock, N. Aggarwal, D. Polidori, Y. Zhao, D. Arbit, K. Usiskin, and et al. Effects of canagliflozin, a sodium-glucose cotransporter 2 inhibitor, as add-on to metformin in subjects with type 2 diabetes Diabetes Care 35 June (6) 2012 1232 1238
    • (2012) Diabetes Care , vol.35 , pp. 1232-1238
    • Rosenstock, J.1    Aggarwal, N.2    Polidori, D.3    Zhao, Y.4    Arbit, D.5    Usiskin, K.6
  • 44
    • 84888059660 scopus 로고    scopus 로고
    • Efficacy and safety of canagliflozin in patients with type 2 diabetes mellitusinadequately controlled with metformin and sulphonylurea: A randomised trial
    • J.P. Wilding, G. Charpentier, P. Hollander, G. González-Gálvez, C. Mathieu, F. Vercruysse, and et al. Efficacy and safety of canagliflozin in patients with type 2 diabetes mellitusinadequately controlled with metformin and sulphonylurea: a randomised trial Int. J. Clin. Pract. 67 12 2013 1267 1282
    • (2013) Int. J. Clin. Pract. , vol.67 , Issue.12 , pp. 1267-1282
    • Wilding, J.P.1    Charpentier, G.2    Hollander, P.3    González-Gálvez, G.4    Mathieu, C.5    Vercruysse, F.6
  • 45
    • 84898791440 scopus 로고    scopus 로고
    • Efficacy and safety of canagliflozin over 52 weeks in patients with type 2 diabetes on background metformin and pioglitazone
    • T. Forst, R. Guthrie, R. Goldenberg, J. Yee, U. Vijapurkar, G. Meininger, and et al. Efficacy and safety of canagliflozin over 52 weeks in patients with type 2 diabetes on background metformin and pioglitazone Diabetes Obes. Metab. 16 5 2014 467 477
    • (2014) Diabetes Obes. Metab. , vol.16 , Issue.5 , pp. 467-477
    • Forst, T.1    Guthrie, R.2    Goldenberg, R.3    Yee, J.4    Vijapurkar, U.5    Meininger, G.6
  • 46
    • 84930844091 scopus 로고    scopus 로고
    • Efficacy and safety of canagliflozin, an inhibitor of sodium-glucose cotransporter 2, when used in conjunction with insulin therapy in patients with type 2 diabetes
    • MARCH 3
    • B. Neal, V. Perkovic, Z. de, D. eeuw, K.W. Mahaffey, G. Fulcher, K. Ways, and et al. Efficacy and safety of canagliflozin, an inhibitor of sodium-glucose cotransporter 2, when used in conjunction with insulin therapy in patients with type 2 diabetes Diabetes Care 38 March (3) 2015 403 411 10.2337/dc14-1237
    • (2015) Diabetes Care , vol.38 , pp. 403-411
    • Neal, B.1    Perkovic, V.2    De, Z.3    Eeuw, D.4    Mahaffey, K.W.5    Fulcher, G.6    Ways, K.7
  • 47
    • 84884167643 scopus 로고    scopus 로고
    • Efficacy and safety of canagliflozin versus glimepiride in patients with type 2 diabetes inadequately controlled with metformin (CANTATA-SU): 52 week results from a randomised, double-blind, phase 3 noninferiority trial
    • W.T. Cefalu, L.A. Leiter, K.H. Yoon, P. Arias, L. Niskanen, J. Xie, and et al. Efficacy and safety of canagliflozin versus glimepiride in patients with type 2 diabetes inadequately controlled with metformin (CANTATA-SU): 52 week results from a randomised, double-blind, phase 3 noninferiority trial Lancet 382 9896 2013 941 950
    • (2013) Lancet , vol.382 , Issue.9896 , pp. 941-950
    • Cefalu, W.T.1    Leiter, L.A.2    Yoon, K.H.3    Arias, P.4    Niskanen, L.5    Xie, J.6
  • 48
    • 84940110139 scopus 로고    scopus 로고
    • Canagliflozin provides durable glycemic improvements and body weight reduction over 104 weeks versus glimepiride in patients with type 2 diabetes on metformin: A randomized, double-blind, phase 3 study
    • MARCH 3
    • L.A. Leiter, K.H. Yoon, P. Arias, G. Langslet, J. Xie, D.A. Balis, and et al. Canagliflozin provides durable glycemic improvements and body weight reduction over 104 weeks versus glimepiride in patients with type 2 diabetes on metformin: a randomized, double-blind, phase 3 study Diabetes Care 38 March (3) 2015 355 364
    • (2015) Diabetes Care , vol.38 , pp. 355-364
    • Leiter, L.A.1    Yoon, K.H.2    Arias, P.3    Langslet, G.4    Xie, J.5    Balis, D.A.6
  • 49
    • 84891784200 scopus 로고    scopus 로고
    • Canagliflozin compared with sitagliptin for patients with type 2 diabetes who do not have adequate glycemic control with metformin plus sulfonylurea: A 52-week randomized trial
    • G. Schernthaner, J.L. Gross, J. Rosenstock, M. Guarisco, M. Fu, J. Yee, and et al. Canagliflozin compared with sitagliptin for patients with type 2 diabetes who do not have adequate glycemic control with metformin plus sulfonylurea: a 52-week randomized trial Diabetes Care 36 9 2013 2508 2515
    • (2013) Diabetes Care , vol.36 , Issue.9 , pp. 2508-2515
    • Schernthaner, G.1    Gross, J.L.2    Rosenstock, J.3    Guarisco, M.4    Fu, M.5    Yee, J.6
  • 50
    • 84898854471 scopus 로고    scopus 로고
    • Effects of sodium-glucose co-transporter 2 inhibitors on blood pressure: A systematic review and meta-analysis
    • W.L. Baker, L.R. Smyth, D.M. Riche, E.M. Bourret, K.W. Chamberlin, and W.B. White Effects of sodium-glucose co-transporter 2 inhibitors on blood pressure: a systematic review and meta-analysis J. Am. Soc. Hypertens. 8 2014 262 275
    • (2014) J. Am. Soc. Hypertens. , vol.8 , pp. 262-275
    • Baker, W.L.1    Smyth, L.R.2    Riche, D.M.3    Bourret, E.M.4    Chamberlin, K.W.5    White, W.B.6
  • 51
    • 84957458253 scopus 로고    scopus 로고
    • (empagliflozin) tablets, for oral use [package insert]. Boehringer Ingelheim Pharmaceuticals, Inc, Ridgefield, CT
    • JARDIANCE™ (empagliflozin) tablets, for oral use [package insert]. Boehringer Ingelheim Pharmaceuticals, Inc, Ridgefield, CT; 2014.
    • (2014) JARDIANCE™
  • 53
    • 84879795546 scopus 로고    scopus 로고
    • A Phase IIb, randomized, placebo-controlled study of the SGLT2 inhibitor empagliflozin in patients with type 2 diabetes
    • E. Ferrannini, L. Seman, E. Seewaldt-Becker, S. Hantel, S. Pinnetti, and H.J. Woerle A Phase IIb, randomized, placebo-controlled study of the SGLT2 inhibitor empagliflozin in patients with type 2 diabetes Diabetes Obes. Metab. 15 8 2013 721 728
    • (2013) Diabetes Obes. Metab. , vol.15 , Issue.8 , pp. 721-728
    • Ferrannini, E.1    Seman, L.2    Seewaldt-Becker, E.3    Hantel, S.4    Pinnetti, S.5    Woerle, H.J.6
  • 54
    • 84885954870 scopus 로고    scopus 로고
    • Empagliflozin monotherapy in drug-naIve patients with type 2 diabetes: A randomised,24-week, double-blind, placebo-controlled, parallel group, trial of SGLT2 Inhibitors in Type 2 Diabetes with sitagliptin as active comparator
    • M. Roden, J. Weng, J. Eilbracht, B. Delafont, G. Kim, and H.J. Woerle Empagliflozin monotherapy in drug-naIve patients with type 2 diabetes: a randomised,24-week, double-blind, placebo-controlled, parallel group, trial of SGLT2 Inhibitors in Type 2 Diabetes with sitagliptin as active comparator Lancet Diabetes Endocrinol. 1 3 2013 208 219
    • (2013) Lancet Diabetes Endocrinol. , vol.1 , Issue.3 , pp. 208-219
    • Roden, M.1    Weng, J.2    Eilbracht, J.3    Delafont, B.4    Kim, G.5    Woerle, H.J.6
  • 55
    • 84905393225 scopus 로고    scopus 로고
    • Empagliflozin monotherapy in Japanese patients with type 2 diabetes mellitus: A randomized, 12-week, double-blind, placebo-controlled. Phase II trial
    • T. Kadowaki, M. Haneda, N. Inagaki, Y. Terauchi, A. Taniguchi, K. Koiwai, and et al. Empagliflozin monotherapy in Japanese patients with type 2 diabetes mellitus:a randomized, 12-week, double-blind, placebo-controlled. Phase II trial Adv. Ther. 31 6 2014 621 638
    • (2014) Adv. Ther. , vol.31 , Issue.6 , pp. 621-638
    • Kadowaki, T.1    Haneda, M.2    Inagaki, N.3    Terauchi, Y.4    Taniguchi, A.5    Koiwai, K.6
  • 56
    • 84887191925 scopus 로고    scopus 로고
    • Efficacy and safety of empagliflozin, a sodium glucose cotransporter 2 (SGLT2) inhibitor, as add-on to metformin in type 2 diabetes with mild hyperglycaemia
    • J. Rosenstock, L.J. Seman, A. Jelaska, S. Hantel, S. Pinnetti, T. Hach, and et al. Efficacy and safety of empagliflozin, a sodium glucose cotransporter 2 (SGLT2) inhibitor, as add-on to metformin in type 2 diabetes with mild hyperglycaemia Diabetes Obes. Metab. 15 12 2013 1154 1160
    • (2013) Diabetes Obes. Metab. , vol.15 , Issue.12 , pp. 1154-1160
    • Rosenstock, J.1    Seman, L.J.2    Jelaska, A.3    Hantel, S.4    Pinnetti, S.5    Hach, T.6
  • 57
    • 84901455931 scopus 로고    scopus 로고
    • Empagliflozin as add-on to metformin in patients with type 2 diabetes: A 24-week, randomized, double-blind, placebo-controlled trial
    • H.U. Häring, L. Merker, E. Seewaldt-Becker, M. Weimer, T. Meinicke, and U.C. Broedl Empagliflozin as add-on to metformin in patients with type 2 diabetes: a 24-week, randomized, double-blind, placebo-controlled trial Diabetes Care 37 6 2014 1650 1659
    • (2014) Diabetes Care , vol.37 , Issue.6 , pp. 1650-1659
    • Häring, H.U.1    Merker, L.2    Seewaldt-Becker, E.3    Weimer, M.4    Meinicke, T.5    Broedl, U.C.6
  • 58
    • 84892477577 scopus 로고    scopus 로고
    • Empagliflozin improves glycaemic and weight control as add-on therapy to pioglitazone or pioglitazone plus metformin in patients with type 2 diabetes: A 24-week, randomized, placebo-controlled trial
    • C.S. Kovacs, V. Seshiah, R. Swallow, R. Jones, H. Rattunde, H.J. Woerle, and et al. Empagliflozin improves glycaemic and weight control as add-on therapy to pioglitazone or pioglitazone plus metformin in patients with type 2 diabetes: a 24-week, randomized, placebo-controlled trial Diabetes Obes. Metab. 16 2 2014 147 158
    • (2014) Diabetes Obes. Metab. , vol.16 , Issue.2 , pp. 147-158
    • Kovacs, C.S.1    Seshiah, V.2    Swallow, R.3    Jones, R.4    Rattunde, H.5    Woerle, H.J.6
  • 59
    • 84885952950 scopus 로고    scopus 로고
    • Empagliflozin as add-on to metformin plus sulfonylurea in patients with type 2 diabetes: A 24-week, randomized, double-blind, placebo-controlled trial
    • H.U. Häring, L. Merker, E. Seewaldt-Becker, M. Weimer, T. Meinicke, H.J. Woerle, and et al. Empagliflozin as add-on to metformin plus sulfonylurea in patients with type 2 diabetes: a 24-week, randomized, double-blind, placebo-controlled trial Diabetes Care 36 11 2013 3396 3404
    • (2013) Diabetes Care , vol.36 , Issue.11 , pp. 3396-3404
    • Häring, H.U.1    Merker, L.2    Seewaldt-Becker, E.3    Weimer, M.4    Meinicke, T.5    Woerle, H.J.6
  • 60
    • 84903511385 scopus 로고    scopus 로고
    • Improved glucose control with weight loss, lower insulin doses, and no increased hypoglycemia with empagliflozin added to titrated multiple daily injections of insulin in obese inadequately controlled type 2 diabetes
    • J. Rosenstock, A. Jelaska, G. Frappin, A. Salsali, G. Kim, H.J. Woerle, and et al. Improved glucose control with weight loss, lower insulin doses, and no increased hypoglycemia with empagliflozin added to titrated multiple daily injections of insulin in obese inadequately controlled type 2 diabetes Diabetes Care 37 7 2014 1815 1823
    • (2014) Diabetes Care , vol.37 , Issue.7 , pp. 1815-1823
    • Rosenstock, J.1    Jelaska, A.2    Frappin, G.3    Salsali, A.4    Kim, G.5    Woerle, H.J.6
  • 62
    • 84879795546 scopus 로고    scopus 로고
    • A Phase IIb, randomized, placebo-controlled study of the SGLT2 inhibitor empagliflozin in patients with type 2 diabetes
    • E. Ferrannini, L. Seman, E. Seewaldt-Becker, S. Hantel, S. Pinnetti, and H.J. Woerle A Phase IIb, randomized, placebo-controlled study of the SGLT2 inhibitor empagliflozin in patients with type 2 diabetes Diabetes Obes. Metab. 15 8 2013 721 728
    • (2013) Diabetes Obes. Metab. , vol.15 , Issue.8 , pp. 721-728
    • Ferrannini, E.1    Seman, L.2    Seewaldt-Becker, E.3    Hantel, S.4    Pinnetti, S.5    Woerle, H.J.6
  • 63
    • 84908332537 scopus 로고    scopus 로고
    • Comparison of empagliflozin and glimepiride as add-on to metformin in patients with type 2 diabetes: A 104-week randomised, active -controlled, double-blind, phase 3 trial
    • M. Ridderstråle, K.R. Andersen, C. Zeller, G. Kim, H.J. Woerle, U.C. Broedl, and et al. Comparison of empagliflozin and glimepiride as add-on to metformin in patients with type 2 diabetes: a 104-week randomised, active -controlled, double-blind, phase 3 trial Lancet Diabetes Endocrinol. 2 9 2014 691 700
    • (2014) Lancet Diabetes Endocrinol. , vol.2 , Issue.9 , pp. 691-700
    • Ridderstråle, M.1    Andersen, K.R.2    Zeller, C.3    Kim, G.4    Woerle, H.J.5    Broedl, U.C.6
  • 64
    • 84928199102 scopus 로고    scopus 로고
    • Initial combination of empagliflozin and linagliptin in subjects with type 2 diabetes
    • Mar
    • A. Lewin, R.A. DeFronzo, S. Patel, D. Liu, R. Kaste, H.J. Woerle, and et al. Initial combination of empagliflozin and linagliptin in subjects with type 2 diabetes Diabetes Care 38 3 2015 Mar 394 402
    • (2015) Diabetes Care , vol.38 , Issue.3 , pp. 394-402
    • Lewin, A.1    DeFronzo, R.A.2    Patel, S.3    Liu, D.4    Kaste, R.5    Woerle, H.J.6
  • 65
    • 84928176749 scopus 로고    scopus 로고
    • Combination of empagliflozin and linagliptin as second-line therapy in subjects with type 2 diabetes inadequately controlled on metformin
    • MARCH 3
    • R.A. DeFronzo, A. Lewin, S. Patel, D. Liu, R. Kaste, H.J. Woerle, and et al. Combination of empagliflozin and linagliptin as second-line therapy in subjects with type 2 diabetes inadequately controlled on metformin Diabetes Care 38 March (3) 2015 384 393
    • (2015) Diabetes Care , vol.38 , pp. 384-393
    • DeFronzo, R.A.1    Lewin, A.2    Patel, S.3    Liu, D.4    Kaste, R.5    Woerle, H.J.6
  • 66
    • 84957458254 scopus 로고    scopus 로고
    • (dapagliflozin) tablets, for oral use [package insert]. Bristol-Myers Squibb Company, Princeton, NJ
    • FARXIGA™ (dapagliflozin) tablets, for oral use [package insert]. Bristol-Myers Squibb Company, Princeton, NJ; 2014.
    • (2014) FARXIGA™
  • 67
    • 84930825790 scopus 로고    scopus 로고
    • Dapagliflozin improves glycemic control and reduces body weight as add-on therapy to metformin plus sulfonylurea: A 24-week randomized, double-blind clinical trial
    • MARCH 3
    • S. Matthaei, K. Bowering, K. Rohwedder, A. Grohl, and S. Parikh Dapagliflozin improves glycemic control and reduces body weight as add-on therapy to metformin plus sulfonylurea: a 24-week randomized, double-blind clinical trial Diabetes Care 38 March (3) 2015 365 372
    • (2015) Diabetes Care , vol.38 , pp. 365-372
    • Matthaei, S.1    Bowering, K.2    Rohwedder, K.3    Grohl, A.4    Parikh, S.5
  • 68
    • 84928201032 scopus 로고    scopus 로고
    • Dual add-on therapy in type 2 diabetes poorly controlled with metformin monotherapy: A randomized double-blind trial of saxagliptin plus dapagliflozin addition versus single addition of saxagliptin or dapagliflozin to metformin
    • MARCH 3
    • J. Rosenstock, L. Hansen, P. Zee, Y. Li, W. Cook, B. Hirshberg, and et al. Dual add-on therapy in type 2 diabetes poorly controlled with metformin monotherapy: a randomized double-blind trial of saxagliptin plus dapagliflozin addition versus single addition of saxagliptin or dapagliflozin to metformin Diabetes Care 38 March (3) 2015 376 383
    • (2015) Diabetes Care , vol.38 , pp. 376-383
    • Rosenstock, J.1    Hansen, L.2    Zee, P.3    Li, Y.4    Cook, W.5    Hirshberg, B.6
  • 70
    • 84892479365 scopus 로고    scopus 로고
    • Dapagliflozin maintains glycaemic control while reducing weight and body fat mass over 2 years in patients with type 2 diabetes mellitus inadequately controlled on metformin
    • J. Bolinder, Ö. Ljunggren, L. Johansson, J. Wilding, A.M. Langkilde, C.D. Sjöström, and et al. Dapagliflozin maintains glycaemic control while reducing weight and body fat mass over 2 years in patients with type 2 diabetes mellitus inadequately controlled on metformin Diabetes Obes. Metab. 16 2 2014 159 169
    • (2014) Diabetes Obes. Metab. , vol.16 , Issue.2 , pp. 159-169
    • Bolinder, J.1    Ljunggren, Ö.2    Johansson, L.3    Wilding, J.4    Langkilde, A.M.5    Sjöström, C.D.6
  • 71
    • 84867142771 scopus 로고    scopus 로고
    • Dapagliflozin has no effect on markers of bone formation and resorption or bone mineral density in patients with inadequately controlled type 2 diabetes mellitus on metformin
    • Ö. Ljunggren, J. Bolinder, L. Johansson, J. Wilding, A.M. Langkilde, C.D. Sjöström, and et al. Dapagliflozin has no effect on markers of bone formation and resorption or bone mineral density in patients with inadequately controlled type 2 diabetes mellitus on metformin Diabetes Obes. Metab. 14 11 2012 990 999
    • (2012) Diabetes Obes. Metab. , vol.14 , Issue.11 , pp. 990-999
    • Ljunggren, Ö.1    Bolinder, J.2    Johansson, L.3    Wilding, J.4    Langkilde, A.M.5    Sjöström, C.D.6
  • 72
    • 84934442921 scopus 로고    scopus 로고
    • Exploring the potential of the sglt2 inhibitor dapagliflozin in type 1 diabetes: A randomized, double-blind, placebo-controlled pilot study
    • MARCH
    • R.R. Henry, J. Rosenstock, S. Edelman, S. Mudaliar, A.G. Chalamandaris, S. Kasichayanula, and et al. Exploring the potential of the sglt2 inhibitor dapagliflozin in type 1 diabetes: a randomized, double-blind, placebo-controlled pilot study Diabetes Care 38 March 2015 412 419
    • (2015) Diabetes Care , vol.38 , pp. 412-419
    • Henry, R.R.1    Rosenstock, J.2    Edelman, S.3    Mudaliar, S.4    Chalamandaris, A.G.5    Kasichayanula, S.6
  • 73
    • 84899535874 scopus 로고    scopus 로고
    • The efficacy of dapagliflozin combined with hypoglycaemic drugs in treating type 2 diabetes mellitus: Meta-analysis of randomized controlled trials
    • Y.N. Sun, Y. Zhou, X. Chen, W.S. Che, and S.W. Leung The efficacy of dapagliflozin combined with hypoglycaemic drugs in treating type 2 diabetes mellitus: meta-analysis of randomized controlled trials BMJ Open 4 4 2014 e:004619
    • (2014) BMJ Open , vol.4 , Issue.4 , pp. e004619
    • Sun, Y.N.1    Zhou, Y.2    Chen, X.3    Che, W.S.4    Leung, S.W.5
  • 74
    • 84923791994 scopus 로고    scopus 로고
    • Efficacy, and safety of sodium-glucose co-transporter type 2 (SGLT2) inhibitors for the treatment of type 2 diabetes mellitus
    • A.J.P. Scheen, and harmacodynamics efficacy, and safety of sodium-glucose co-transporter type 2 (SGLT2) inhibitors for the treatment of type 2 diabetes mellitus Drugs 75 2015 33 59
    • (2015) Drugs , vol.75 , pp. 33-59
    • Scheen, A.J.P.1    Harmacodynamics2
  • 75
    • 84858020943 scopus 로고    scopus 로고
    • Effects of dapagliflozin on body weight, total fat mass, and regional adipose tissue distribution in patients with type 2 diabetes mellitus with inadequate glycemic control on metformin
    • J. Bolinder, Ö. Ljunggren, J. Kullberg, L. Johansson, J. Wilding, A.M. Langkilde, and et al. Effects of dapagliflozin on body weight, total fat mass, and regional adipose tissue distribution in patients with type 2 diabetes mellitus with inadequate glycemic control on metformin J. Clin. Endocrinol. Metab. 97 3 2012 1020 1031
    • (2012) J. Clin. Endocrinol. Metab. , vol.97 , Issue.3 , pp. 1020-1031
    • Bolinder, J.1    Ljunggren, Ö.2    Kullberg, J.3    Johansson, L.4    Wilding, J.5    Langkilde, A.M.6
  • 76
    • 84892479365 scopus 로고    scopus 로고
    • Dapagliflozin maintains glycaemic control while reducing weight and body fat mass over 2 years in patients with type 2 diabetes mellitus inadequately controlled on metformin
    • J. Bolinder, Ö. Ljunggren, L. Johansson, J. Wilding, A.M. Langkilde, C.D. Sjöström, and et al. Dapagliflozin maintains glycaemic control while reducing weight and body fat mass over 2 years in patients with type 2 diabetes mellitus inadequately controlled on metformin Diabetes Obes. Metab. 16 2 2014 159 169
    • (2014) Diabetes Obes. Metab. , vol.16 , Issue.2 , pp. 159-169
    • Bolinder, J.1    Ljunggren, Ö.2    Johansson, L.3    Wilding, J.4    Langkilde, A.M.5    Sjöström, C.D.6
  • 77
    • 84918523582 scopus 로고    scopus 로고
    • Tofogliflozin: A highly selective SGLT2 inhibitor for the treatment of type 2 diabetes
    • NOVEMBER 11
    • R.F. Rosenwasser, J.N. Rosenwasser, D. Sutton, R. Choksi, and B. Epstein Tofogliflozin: a highly selective SGLT2 inhibitor for the treatment of type 2 diabetes Drugs Today (Barc) 50 November (11) 2014 739 745
    • (2014) Drugs Today (Barc) , vol.50 , pp. 739-745
    • Rosenwasser, R.F.1    Rosenwasser, J.N.2    Sutton, D.3    Choksi, R.4    Epstein, B.5
  • 78
    • 84874977086 scopus 로고    scopus 로고
    • Effects of LX4211, a dual SGLT1/SGLT2 inhibitor, plus sitagliptin on postprandial active GLP-1 and glycemic control in type 2 diabetes
    • Mar
    • B. Zambrowicz, Z.M. Ding, I. Ogbaa, K. Frazier, P. Banks, A. Turnage, and et al. Effects of LX4211, a dual SGLT1/SGLT2 inhibitor, plus sitagliptin on postprandial active GLP-1 and glycemic control in type 2 diabetes Clin. Ther. 35 3 2013 Mar 273 285
    • (2013) Clin. Ther. , vol.35 , Issue.3 , pp. 273-285
    • Zambrowicz, B.1    Ding, Z.M.2    Ogbaa, I.3    Frazier, K.4    Banks, P.5    Turnage, A.6
  • 79
    • 84864146681 scopus 로고    scopus 로고
    • LX4211, a dual SGLT1/SGLT2 inhibitor, improved glycemic control in patients with type 2 diabetes in a randomized, placebo-controlled trial
    • AUGUST 2
    • B. Zambrowicz, J. Freiman, P.M. Brown, K.S. Frazier, A. Turnage, J. Bronner, and et al. LX4211, a dual SGLT1/SGLT2 inhibitor, improved glycemic control in patients with type 2 diabetes in a randomized, placebo-controlled trial Clin. Pharmacol. Ther. 92 August (2) 2012 158 169
    • (2012) Clin. Pharmacol. Ther. , vol.92 , pp. 158-169
    • Zambrowicz, B.1    Freiman, J.2    Brown, P.M.3    Frazier, K.S.4    Turnage, A.5    Bronner, J.6


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