The EF-hand Ca2+ binding domain is not required for cytosolic Ca2+ activation of the cardiac ryanodine receptor

Journal of Biological Chemistry

Volumn 291, Issue 5, 2016, Pages 2150-2160

  Guo, Wenting ^a   Sun, Bo ^a   Xiao, Zhichao ^a   Liu, Yingjie ^a   Wang, Yundi ^a   Zhang, Lin ^a   Wang, Ruiwu ^a   Chen, S R Wayne ^a  

^a UNIVERSITY OF CALGARY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

BINS; CHEMICAL ACTIVATION; INSECTICIDES;

BINDING DOMAIN; CARDIAC RYANODINE RECEPTOR; EF-HAND MOTIF; HEK293 CELLS; MOLECULAR BASIS; RYANODINE; RYANODINE RECEPTORS; SKELETAL MUSCLE;

CALCIUM;

CALCIUM ION; RYANODINE RECEPTOR 2; CALCIUM; PROTEIN BINDING; RYANODINE RECEPTOR;

AMINO ACID SEQUENCE; ARTICLE; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CALCIUM TRANSPORT; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DELETION MUTANT; EF HAND CALCIUM BINDING DOMAIN; HEK293 CELL LINE; MOLECULAR DYNAMICS; MUTATIONAL ANALYSIS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; REFERENCE VALUE; SENSITIVITY ANALYSIS; STORE OVERLOAD INDUCED CALCIUM RELEASE; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; CYTOSOL; DENSITY GRADIENT CENTRIFUGATION; GENE DELETION; HUMAN; METABOLISM; MUTATION; PROTEIN MOTIF; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE;

CALCIUM; CENTRIFUGATION, DENSITY GRADIENT; CYTOSOL; EF HAND MOTIFS; GENE DELETION; HEK293 CELLS; HUMANS; MUTATION; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL;

EID: 84957030539     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.693325     Document Type: Article

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