TRPC6 is required for hypoxia-induced basal intracellular calcium concentration elevation, and for the proliferation and migration of rat distal pulmonary venous smooth muscle cells

Molecular Medicine Reports

Volumn 13, Issue 2, 2016, Pages 1577-1585

  Wang, Qingjie ^a   Wang, Dong ^a   Yan, Gaoling ^a   Sun, Ling ^b   Tang, Chengchun ^a  

^a AFFILIATED ZHONGDA HOSPITAL OF SOUTHEAST UNIVERSITY   (China)

^b NANJING MEDICAL UNIVERSITY   (China)

Author keywords

AMP activated kinase; Chronic hypoxic pulmonary hypertension; Pulmonary artery smooth muscle cells; Transient receptor potential cation channel

Indexed keywords

BETA ACTIN; MESSENGER RNA; NIFEDIPINE; SMALL INTERFERING RNA; TRANSIENT RECEPTOR POTENTIAL CHANNEL 1; TRANSIENT RECEPTOR POTENTIAL CHANNEL 6; VOLTAGE GATED CALCIUM CHANNEL; CALCIUM; TRANSIENT RECEPTOR POTENTIAL CHANNEL C; TRPC6 PROTEIN, RAT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALCIUM CELL LEVEL; CELL MIGRATION; CELL PROLIFERATION; CONTROLLED STUDY; DISTAL PULMONARY VENOUS SMOOTH MUSCLE CELL; HYPOXIA; IMMUNOFLUORESCENCE; IN VITRO STUDY; IN VIVO STUDY; MALE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN EXPRESSION; PULMONARY ARTERY SMOOTH MUSCLE CELL; PULMONARY HYPERTENSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; UPREGULATION; ANIMAL; CELL HYPOXIA; CELL MOTION; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; PATHOLOGY; PULMONARY ARTERY; PULMONARY VEIN; VASCULAR SMOOTH MUSCLE;

ANIMALS; CALCIUM; CELL HYPOXIA; CELL MOVEMENT; CELL PROLIFERATION; GENE EXPRESSION REGULATION; HUMANS; HYPERTENSION, PULMONARY; MUSCLE, SMOOTH, VASCULAR; PULMONARY ARTERY; PULMONARY VEINS; RATS; TRPC CATION CHANNELS;

EID: 84956935647     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2015.4750     Document Type: Article

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