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Journal of Experimental Medicine

Volumn 212, Issue 7, 2015, Pages 1011-1020

The lysophosphatidylserine receptor GPR174 constrains regulatory T cell development and function

(6) Barnes, Michael J a,b Li, Chien Ming a Xu, Ying a,b An, Jinping a,b Huang, Yong a Cyster, Jason G a,b

a UNIVERSITY OF CALIFORNIA (United States)

b UNIVERSITY OF CALIFORNIA (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD103 ANTIGEN; G PROTEIN COUPLED RECEPTOR; LYSOPHOSPHATIDYLSERINE; PROTEIN GPR174; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG; ALPHA E INTEGRINS; ALPHA INTEGRIN; GPR174 PROTEIN, MOUSE; LEUKOCYTE ANTIGEN; LYSOPHOSPHOLIPID; LYSOPHOSPHOLIPID RECEPTOR; PRIMER DNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; CD4+ T LYMPHOCYTE; CELL LINE; CELL MATURATION; COLON; CONTROLLED STUDY; EXPERIMENTAL AUTOIMMUNE ENCEPHALOMYELITIS; HOMEOSTASIS; IMMUNOREGULATION; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE FUNCTION; LYMPHOCYTE PROLIFERATION; LYMPHOID ORGAN; MOUSE; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REGULATORY T LYMPHOCYTE; SPINAL CORD; TH1 CELL; THYMUS; WILD TYPE MOUSE; ANIMAL; CELL PROLIFERATION; CYTOLOGY; FLOW CYTOMETRY; IMMUNOLOGY; LIQUID CHROMATOGRAPHY; LYMPHOID TISSUE; METABOLISM; TANDEM MASS SPECTROMETRY;

ANIMALS; ANTIGENS, CD; CELL PROLIFERATION; CHROMATOGRAPHY, LIQUID; COLON; DNA PRIMERS; FLOW CYTOMETRY; HOMEOSTASIS; INTEGRIN ALPHA CHAINS; LYMPHOID TISSUE; LYSOPHOSPHOLIPIDS; MICE; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, LYSOPHOSPHOLIPID; SPINAL CORD; T-LYMPHOCYTES, REGULATORY; TANDEM MASS SPECTROMETRY;

EID: 84956921918 PISSN: 00221007 EISSN: 15409538 Source Type: Journal
DOI: 10.1084/jem.20141827 Document Type: Article

Times cited : (66)

References (33)

1
- 0027497393
- Role of a serum phospholipase A1 in the phosphatidylserine-induced T cell inhibition
- Bellini, F., and A. Bruni. 1993. Role of a serum phospholipase A1 in the phosphatidylserine-induced T cell inhibition. FEBS Lett. 316:1-4. http://dx.doi.org/10.1016/0014-5793(93)81724-E
- (1993) FEBS Lett. , vol.316 , pp. 1-4
- Bellini, F.¹ Bruni, A.²

2
- 84872867557
- ABHD12 controls brain lysophosphatidylserine pathways that are deregulated in a murine model of the neurodegenerative disease PHARC
- Blankman, J.L., J.Z. Long, S.A. Trauger, G. Siuzdak, and B.F. Cravatt. 2013. ABHD12 controls brain lysophosphatidylserine pathways that are deregulated in a murine model of the neurodegenerative disease PHARC. Proc. Natl. Acad. Sci. USA. 110:1500-1505. http://dx.doi .org/10.1073/pnas.1217121110
- (2013) Proc. Natl. Acad. Sci. USA. , vol.110 , pp. 1500-1505
- Blankman, J.L.¹ Long, J.Z.² Trauger, S.A.³ Siuzdak, G.⁴ Cravatt, B.F.⁵

3
- 84888872209
- Controlling the frontier: regulatory T-cells and intestinal homeostasis
- Bollrath, J., and F.M. Powrie. 2013. Controlling the frontier: regulatory T-cells and intestinal homeostasis. Semin. Immunol. 25:352-357. http:// dx.doi.org/10.1016/j.smim.2013.09.002
- (2013) Semin. Immunol. , vol.25 , pp. 352-357
- Bollrath, J.¹ Powrie, F.M.²

4
- 79251500661
- + regulatory T cells
- + regulatory T cells. Nat. Rev. Immunol. 11:119-130. http://dx.doi.org/10.1038/nri2916
- (2011) Nat. Rev. Immunol. , vol.11 , pp. 119-130
- Campbell, D.J.¹ Koch, M.A.²

5
- 84883199435
- An X chromosome-wide association analysis identifies variants in GPR174 as a risk factor for Graves' disease
- Chu, X., M. Shen, F. Xie, X.J. Miao, W.H. Shou, L. Liu, P.P. Yang, Y.N. Bai, K.Y. Zhang, L. Yang, et al. 2013. An X chromosome-wide association analysis identifies variants in GPR174 as a risk factor for Graves' disease. J. Med. Genet. 50:479-485. http://dx.doi.org/10.1136/ jmedgenet-2013-101595
- (2013) J. Med. Genet. , vol.50 , pp. 479-485
- Chu, X.¹ Shen, M.² Xie, F.³ Miao, X.J.⁴ Shou, W.H.⁵ Liu, L.⁶ Yang, P.P.⁷ Bai, Y.N.⁸ Zhang, K.Y.⁹ Yang, L.¹⁰

6
- 79956315886
- Intestinal bacterial colonization induces mutualistic regulatory T cell responses
- Geuking, M.B., J. Cahenzli, M.A. Lawson, D.C. Ng, E. Slack, S. Hapfelmeier, K.D. McCoy, and A.J. Macpherson. 2011. Intestinal bacterial colonization induces mutualistic regulatory T cell responses. Immunity. 34:794- 806. http://dx.doi.org/10.1016/j.immuni.2011.03.021
- (2011) Immunity. , vol.34 , pp. 794- 806
- Geuking, M.B.¹ Cahenzli, J.² Lawson, M.A.³ Ng, D.C.⁴ Slack, E.⁵ Hapfelmeier, S.⁶ McCoy, K.D.⁷ Macpherson, A.J.⁸

7
- 84874648526
- Novel bioactive glycerol-based lysophospholipids: new data - new insight into their function
- Grzelczyk, A., and E. Gendaszewska-Darmach. 2013. Novel bioactive glycerol-based lysophospholipids: new data - new insight into their function. Biochimie. 95:667-679. http://dx.doi.org/10.1016/j.biochi .2012.10.009
- (2013) Biochimie. , vol.95 , pp. 667-679
- Grzelczyk, A.¹ Gendaszewska-Darmach, E.²

8
- 79960438236
- The role of retinoic acid in tolerance and immunity
- Hall, J.A., J.R. Grainger, S.P. Spencer, and Y. Belkaid. 2011. The role of retinoic acid in tolerance and immunity. Immunity. 35:13-22. http:// dx.doi.org/10.1016/j.immuni.2011.07.002
- (2011) Immunity. , vol.35 , pp. 13-22
- Hall, J.A.¹ Grainger, J.R.² Spencer, S.P.³ Belkaid, Y.⁴

9
- 10744221289
- + regulatory T cells
- + regulatory T cells. J. Exp. Med. 199:303- 313. http://dx.doi.org/10.1084/jem.20031562
- (2004) J. Exp. Med. , vol.199 , pp. 303- 313
- Huehn, J.¹ Siegmund, K.² Lehmann, J.C.³ Siewert, C.⁴ Haubold, U.⁵ Feuerer, M.⁶ Debes, G.F.⁷ Lauber, J.⁸ Frey, O.⁹ Przybylski, G.K.¹⁰

10
- 84867001160
- TGFα shedding assay: an accurate and versatile method for detecting GPCR activation
- Inoue, A., J. Ishiguro, H. Kitamura, N. Arima, M. Okutani, A. Shuto, S. Higashiyama, T. Ohwada, H. Arai, K. Makide, and J. Aoki. 2012. TGFα shedding assay: an accurate and versatile method for detecting GPCR activation. Nat. Methods. 9:1021-1029. http://dx.doi.org/ 10.1038/nmeth.2172
- (2012) Nat. Methods. , vol.9 , pp. 1021-1029
- Inoue, A.¹ Ishiguro, J.² Kitamura, H.³ Arima, N.⁴ Okutani, M.⁵ Shuto, A.⁶ Higashiyama, S.⁷ Ohwada, T.⁸ Arai, H.⁹ Makide, K.¹⁰ Aoki, J.¹¹

11
- 84859416933
- Regulatory T cells: mechanisms of differentiation and function
- Josefowicz, S.Z., L.F. Lu, and A.Y. Rudensky. 2012. Regulatory T cells: mechanisms of differentiation and function. Annu. Rev. Immunol. 30:531- 564. http://dx.doi.org/10.1146/annurev.immunol.25.022106.141623
- (2012) Annu. Rev. Immunol. , vol.30 , pp. 531- 564
- Josefowicz, S.Z.¹ Lu, L.F.² Rudensky, A.Y.³

12
- 84961288408
- Immunomodulatory lysophosphatidylserines are regulated by ABHD16A and ABHD12 interplay
- Kamat, S.S., K. Camara, W.H. Parsons, D.H. Chen, M.M. Dix, T.D. Bird, A.R. Howell, and B.F. Cravatt. 2015. Immunomodulatory lysophosphatidylserines are regulated by ABHD16A and ABHD12 interplay. Nat. Chem. Biol. 11:164-171. http://dx.doi.org/10.1038/nchembio.1721
- (2015) Nat. Chem. Biol. , vol.11 , pp. 164-171
- Kamat, S.S.¹ Camara, K.² Parsons, W.H.³ Chen, D.H.⁴ Dix, M.M.⁵ Bird, T.D.⁶ Howell, A.R.⁷ Cravatt, B.F.⁸

13
- 84860492147
- GPR34 is a receptor for lysophosphatidylserine with a fatty acid at the sn-2 position
- Kitamura, H., K. Makide, A. Shuto, M. Ikubo, A. Inoue, K. Suzuki, Y. Sato, S. Nakamura, Y. Otani, T. Ohwada, and J. Aoki. 2012. GPR34 is a receptor for lysophosphatidylserine with a fatty acid at the sn-2 position. J. Biochem. 151:511-518. http://dx.doi.org/10.1093/jb/mvs011
- (2012) J. Biochem. , vol.151 , pp. 511-518
- Kitamura, H.¹ Makide, K.² Shuto, A.³ Ikubo, M.⁴ Inoue, A.⁵ Suzuki, K.⁶ Sato, Y.⁷ Nakamura, S.⁸ Otani, Y.⁹ Ohwada, T.¹⁰ Aoki, J.¹¹

14
- 0036791004
- - regulatory T cells
- - regulatory T cells. Proc. Natl. Acad. Sci. USA. 99:13031-13036. http:// dx.doi.org/10.1073/pnas.192162899
- (2002) Proc. Natl. Acad. Sci. USA. , vol.99 , pp. 13031-13036
- Lehmann, J.¹ Huehn, J.² de la Rosa, M.³ Maszyna, F.⁴ Kretschmer, U.⁵ Krenn, V.⁶ Brunner, M.⁷ Scheffold, A.⁸ Hamann, A.⁹

15
- 78751504780
- Altered immune response in mice deficient for the G protein-coupled receptor GPR34
- Liebscher, I., U. Müller, D. Teupser, E. Engemaier, K.M. Engel, L. Ritscher, D. Thor, K. Sangkuhl, A. Ricken, A. Wurm, et al. 2011. Altered immune response in mice deficient for the G protein-coupled receptor GPR34. J. Biol. Chem. 286:2101-2110. http://dx.doi.org/10.1074/jbc .M110.196659
- (2011) J. Biol. Chem. , vol.286 , pp. 2101-2110
- Liebscher, I.¹ Müller, U.² Teupser, D.³ Engemaier, E.⁴ Engel, K.M.⁵ Ritscher, L.⁶ Thor, D.⁷ Sangkuhl, K.⁸ Ricken, A.⁹ Wurm, A.¹⁰

16
- 67649185215
- The receptor S1P1 overrides regulatory T cell-mediated immune suppression through Akt-mTOR
- Liu, G., S. Burns, G. Huang, K. Boyd, R.L. Proia, R.A. Flavell, and H. Chi. 2009. The receptor S1P1 overrides regulatory T cell-mediated immune suppression through Akt-mTOR. Nat. Immunol. 10:769-777. http:// dx.doi.org/10.1038/ni.1743
- (2009) Nat. Immunol. , vol.10 , pp. 769-777
- Liu, G.¹ Burns, S.² Huang, G.³ Boyd, K.⁴ Proia, R.L.⁵ Flavell, R.A.⁶ Chi, H.⁷

17
- 84899475568
- Costimulation via the tumor-necrosis factor receptor superfamily couples TCR signal strength to the thymic differentiation of regulatory T cells
- Mahmud, S.A., L.S. Manlove, H.M. Schmitz, Y. Xing, Y. Wang, D.L. Owen, J.M. Schenkel, J.S. Boomer, J.M. Green, H. Yagita, et al. 2014. Costimulation via the tumor-necrosis factor receptor superfamily couples TCR signal strength to the thymic differentiation of regulatory T cells. Nat. Immunol. 15:473-481. http://dx.doi.org/10.1038/ni.2849
- (2014) Nat. Immunol. , vol.15 , pp. 473-481
- Mahmud, S.A.¹ Manlove, L.S.² Schmitz, H.M.³ Xing, Y.⁴ Wang, Y.⁵ Owen, D.L.⁶ Schenkel, J.M.⁷ Boomer, J.S.⁸ Green, J.M.⁹ Yagita, H.¹⁰

18
- 0018774369
- Interactions of lysophospholipids and mast cells
- Martin, T.W., and D. Lagunoff. 1979. Interactions of lysophospholipids and mast cells. Nature. 279:250-252. http://dx.doi.org/10.1038/279250a0
- (1979) Nature. , vol.279 , pp. 250-252
- Martin, T.W.¹ Lagunoff, D.²

19
- 0036195161
- + immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid- induced TNF receptor
- + immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid- induced TNF receptor. Immunity. 16:311-323. http://dx.doi .org/10.1016/S1074-7613(02)00280-7
- (2002) Immunity. , vol.16 , pp. 311-323
- McHugh, R.S.¹ Whitters, M.J.² Piccirillo, C.A.³ Young, D.A.⁴ Shevach, E.M.⁵ Collins, M.⁶ Byrne, M.C.⁷

20
- 79958251745
- T cell receptor signal strength in Treg and iNKT cell development demonstrated by a novel fluorescent reporter mouse
- reg and iNKT cell development demonstrated by a novel fluorescent reporter mouse. J. Exp. Med. 208:1279-1289. http://dx.doi.org/10.1084/ jem.20110308
- (2011) J. Exp. Med. , vol.208 , pp. 1279-1289
- Moran, A.E.¹ Holzapfel, K.L.² Xing, Y.³ Cunningham, N.R.⁴ Maltzman, J.S.⁵ Punt, J.⁶ Hogquist, K.A.⁷

21
- 84894288992
- Genetics of rheumatoid arthritis contributes to biology and drug discovery
- Okada, Y., D. Wu, G. Trynka, T. Raj, C. Terao, K. Ikari, Y. Kochi, K. Ohmura, A. Suzuki, S. Yoshida, et al. GARNET consortium. 2014. Genetics of rheumatoid arthritis contributes to biology and drug discovery. Nature. 506:376-381. http://dx.doi.org/10.1038/nature12873
- (2014) Nature. , vol.506 , pp. 376-381
- Okada, Y.¹ Wu, D.² Trynka, G.³ Raj, T.⁴ Terao, C.⁵ Ikari, K.⁶ Kochi, Y.⁷ Ohmura, K.⁸ Suzuki, A.⁹ Yoshida, S.¹⁰

22
- 37849033437
- i-coupled receptors to promote T cell egress
- i-coupled receptors to promote T cell egress. Immunity. 28:122-133. http://dx .doi.org/10.1016/j.immuni.2007.11.017
- (2008) Immunity. , vol.28 , pp. 122-133
- Pham, T.H.¹ Okada, T.² Matloubian, M.³ Lo, C.G.⁴ Cyster, J.G.⁵

23
- 84883162955
- + regulatory T cells
- + regulatory T cells. Nat. Immunol. 14:959-965. http://dx.doi.org/10.1038/ni.2649
- (2013) Nat. Immunol. , vol.14 , pp. 959-965
- Pierson, W.¹ Cauwe, B.² Policheni, A.³ Schlenner, S.M.⁴ Franckaert, D.⁵ Berges, J.⁶ Humblet-Baron, S.⁷ Schönefeldt, S.⁸ Herold, M.J.⁹ Hildeman, D.¹⁰

24
- 54549087794
- Anatomical profiling of G protein-coupled receptor expression
- Regard, J.B., I.T. Sato, and S.R. Coughlin. 2008. Anatomical profiling of G protein-coupled receptor expression. Cell. 135:561-571. http://dx.doi .org/10.1016/j.cell.2008.08.040
- (2008) Cell. , vol.135 , pp. 561-571
- Regard, J.B.¹ Sato, I.T.² Coughlin, S.R.³

25
- 0031019017
- Serine phospholipid-specific phospholipase A that is secreted from activated platelets
- Sato, T., J. Aoki, Y. Nagai, N. Dohmae, K. Takio, T. Doi, H. Arai, and K. Inoue. 1997. Serine phospholipid-specific phospholipase A that is secreted from activated platelets. A new member of the lipase family. J. Biol. Chem. 272:2192-2198. http://dx.doi.org/10.1074/jbc.272.4.2192
- (1997) A new member of the lipase family. J. Biol. Chem. , vol.272 , pp. 2192-2198
- Sato, T.¹ Aoki, J.² Nagai, Y.³ Dohmae, N.⁴ Takio, K.⁵ Doi, T.⁶ Arai, H.⁷ Inoue, K.⁸

26
- 84881068658
- The microbial metabolites, short-chain fatty acids, regulate colonic Treg cell homeostasis
- Smith, P.M., M.R. Howitt, N. Panikov, M. Michaud, C.A. Gallini, M. Bohlooly-Y, J.N. Glickman, and W.S. Garrett. 2013. The microbial metabolites, short-chain fatty acids, regulate colonic Treg cell homeostasis. Science. 341:569-573. http://dx.doi.org/10.1126/science .1241165
- (2013) Science. , vol.341 , pp. 569-573
- Smith, P.M.¹ Howitt, M.R.² Panikov, N.³ Michaud, M.⁴ Gallini, C.A.⁵ Bohlooly-Y, M.⁶ Glickman, J.N.⁷ Garrett, W.S.⁸

27
- 34248647881
- Active induction of experimental allergic encephalomyelitis
- Stromnes, I.M., and J.M. Goverman. 2006. Active induction of experimental allergic encephalomyelitis. Nat. Protoc. 1:1810-1819. http://dx.doi .org/10.1038/nprot.2006.285
- (2006) Nat. Protoc. , vol.1 , pp. 1810-1819
- Stromnes, I.M.¹ Goverman, J.M.²

28
- 17844364002
- reg and control of Leishmania major infection
- reg and control of Leishmania major infection. J. Immunol. 174:5444-5455. http://dx.doi.org/10.4049/ jimmunol.174.9.5444
- (2005) J. Immunol. , vol.174 , pp. 5444-5455
- Suffia, I.¹ Reckling, S.K.² Salay, G.³ Belkaid, Y.⁴

29
- 84872410028
- Expression of orphan G-protein coupled receptor GPR174 in CHO cells induced morphological changes and proliferation delay via increasing intracellular cAMP
- Sugita, K., C. Yamamura, K. Tabata, and N. Fujita. 2013. Expression of orphan G-protein coupled receptor GPR174 in CHO cells induced morphological changes and proliferation delay via increasing intracellular cAMP. Biochem. Biophys. Res. Commun. 430:190-195. http://dx.doi .org/10.1016/j.bbrc.2012.11.046
- (2013) Biochem. Biophys. Res. Commun. , vol.430 , pp. 190-195
- Sugita, K.¹ Yamamura, C.² Tabata, K.³ Fujita, N.⁴

30
- 84887014824
- The serine hydrolase ABHD6 is a critical regulator of the metabolic syndrome
- Thomas, G., J.L. Betters, C.C. Lord, A.L. Brown, S. Marshall, D. Ferguson, J. Sawyer, M.A. Davis, J.T. Melchior, L.C. Blume, et al. 2013. The serine hydrolase ABHD6 is a critical regulator of the metabolic syndrome. Cell Reports. 5:508-520. http://dx.doi.org/10.1016/j.celrep.2013.08 .047
- (2013) Cell Reports. , vol.5 , pp. 508-520
- Thomas, G.¹ Betters, J.L.² Lord, C.C.³ Brown, A.L.⁴ Marshall, S.⁵ Ferguson, D.⁶ Sawyer, J.⁷ Davis, M.A.⁸ Melchior, J.T.⁹ Blume, L.C.¹⁰

31
- 84902657771
- Diet, metabolites, and "western-lifestyle" inflammatory diseases
- Thorburn, A.N., L. Macia, and C.R. Mackay. 2014. Diet, metabolites, and "western-lifestyle" inflammatory diseases. Immunity. 40:833-842. http://dx.doi.org/10.1016/j.immuni.2014.05.014
- (2014) Immunity. , vol.40 , pp. 833-842
- Thorburn, A.N.¹ Macia, L.² Mackay, C.R.³

32
- 0031821875
- + immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production
- + immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production. J. Exp. Med. 188:287-296. http://dx.doi .org/10.1084/jem.188.2.287
- (1998) J. Exp. Med. , vol.188 , pp. 287-296
- Thornton, A.M.¹ Shevach, E.M.²

33
- 84881260633
- Robust evidence for five new Graves' disease risk loci from a staged genome-wide association analysis
- Zhao, S.X., L.Q. Xue, W. Liu, Z.H. Gu, C.M. Pan, S.Y. Yang, M. Zhan, H.N. Wang, J. Liang, G.Q. Gao, et al. China Consortium for the Genetics of Autoimmune Thyroid Disease. 2013. Robust evidence for five new Graves' disease risk loci from a staged genome-wide association analysis. Hum. Mol. Genet. 22:3347-3362. http://dx.doi.org/10 .1093/hmg/ddt183
- (2013) Hum. Mol. Genet. , vol.22 , pp. 3347-3362
- Zhao, S.X.¹ Xue, L.Q.² Liu, W.³ Gu, Z.H.⁴ Pan, C.M.⁵ Yang, S.Y.⁶ Zhan, M.⁷ Wang, H.N.⁸ Liang, J.⁹ Gao, G.Q.¹⁰

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