메뉴 건너뛰기




Volumn 13, Issue 2, 2016, Pages 1509-1516

Vaspin attenuates the progression of atherosclerosis by inhibiting ER stress-induced macrophage apoptosis in apoE-/- mice

Author keywords

Apoptosis; Atherosclerosis; Endoplasmic reticulum stress; Macrophages; Vaspin

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 6; APOLIPOPROTEIN E; CASPASE 12; CASPASE 3; CASPASE 9; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; MITOGEN ACTIVATED PROTEIN KINASE P38; OXIDIZED LOW DENSITY LIPOPROTEIN; STRESS ACTIVATED PROTEIN KINASE 1; VASPIN; ADIPOCYTOKINE; SERINE PROTEINASE INHIBITOR; VASPIN PROTEIN, MOUSE;

EID: 84956889021     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2015.4708     Document Type: Article
Times cited : (27)

References (31)
  • 2
    • 40949151070 scopus 로고    scopus 로고
    • Vaspin: A novel serpin with insulin-sensitizing effects
    • Wada J: Vaspin: A novel serpin with insulin-sensitizing effects. Expert Opin Investig Drugs 17: 327-333, 2008.
    • (2008) Expert Opin Investig Drugs , vol.17 , pp. 327-333
    • Wada, J.1
  • 3
    • 78049258257 scopus 로고    scopus 로고
    • Effects of weight reduction on serum vaspin concentrations in obese subjects: Modification by insulin resistance
    • Chang HM, Lee HJ, Park HS, Kang JH, Kim KS, Song YS and Jang YJ: Effects of weight reduction on serum vaspin concentrations in obese subjects: Modification by insulin resistance. Obesity (Silver Spring) 18: 2105-2110, 2010.
    • (2010) Obesity (Silver Spring) , vol.18 , pp. 2105-2110
    • Chang, H.M.1    Lee, H.J.2    Park, H.S.3    Kang, J.H.4    Kim, K.S.5    Song, Y.S.6    Jang, Y.J.7
  • 6
    • 48249120025 scopus 로고    scopus 로고
    • Metformin decreases the adipokine vaspin in overweight women with polycystic ovary syndrome concomitant with improvement in insulin sensitivity and a decrease in insulin resistance
    • Tan BK, Heutling D, Chen J, Farhatullah S, Adya R, Keay SD, Kennedy CR, Lehnert H and Randeva HS: Metformin decreases the adipokine vaspin in overweight women with polycystic ovary syndrome concomitant with improvement in insulin sensitivity and a decrease in insulin resistance. Diabetes 57: 1501-1507, 2008.
    • (2008) Diabetes , vol.57 , pp. 1501-1507
    • Tan, B.K.1    Heutling, D.2    Chen, J.3    Farhatullah, S.4    Adya, R.5    Keay, S.D.6    Kennedy, C.R.7    Lehnert, H.8    Randeva, H.S.9
  • 8
    • 80052838984 scopus 로고    scopus 로고
    • Vaspin plasma concentrations and mRNA expressions in patients with stable and unstable angina pectoris
    • Li HL, Peng WH, Cui ST, Lei H, Wei YD, Li WM and Xu YW: Vaspin plasma concentrations and mRNA expressions in patients with stable and unstable angina pectoris. Clin Chem Lab Med 49: 1547-1554, 2011.
    • (2011) Clin Chem Lab Med , vol.49 , pp. 1547-1554
    • Li, H.L.1    Peng, W.H.2    Cui, S.T.3    Lei, H.4    Wei, Y.D.5    Li, W.M.6    Xu, Y.W.7
  • 9
    • 80053107843 scopus 로고    scopus 로고
    • Vaspin protects vascular endothelial cells against free fatty acid-induced apoptosis through a phosphatidylinositol 3-kinase/Akt pathway
    • Jung CH, Lee WJ, Hwang JY, Seol SM, Kim YM, Lee YL and Park JY: Vaspin protects vascular endothelial cells against free fatty acid-induced apoptosis through a phosphatidylinositol 3-kinase/Akt pathway. Biochem Biophys Res Commun 413: 264-269, 2011.
    • (2011) Biochem Biophys Res Commun , vol.413 , pp. 264-269
    • Jung, C.H.1    Lee, W.J.2    Hwang, J.Y.3    Seol, S.M.4    Kim, Y.M.5    Lee, Y.L.6    Park, J.Y.7
  • 10
    • 84876805071 scopus 로고    scopus 로고
    • Vaspin attenuates high glucose-induced vascular smooth muscle cells proliferation and chemokinesis by inhibiting the MAPK, PI3K/Akt and NF-κB signaling pathways
    • Li H, Peng W, Zhuang J, Lu Y, Jian W, Wei Y, Li W and Xu Y: Vaspin attenuates high glucose-induced vascular smooth muscle cells proliferation and chemokinesis by inhibiting the MAPK, PI3K/Akt and NF-κB signaling pathways. Atherosclerosis 228: 61-68, 2013.
    • (2013) Atherosclerosis , vol.228 , pp. 61-68
    • Li, H.1    Peng, W.2    Zhuang, J.3    Lu, Y.4    Jian, W.5    Wei, Y.6    Li, W.7    Xu, Y.8
  • 12
    • 84874771915 scopus 로고    scopus 로고
    • Visceral adipose tissue-derived serine proteinase inhibitor inhibits apoptosis of endothelial cells as a ligand for the cell-surface GRP78/voltage-dependent anion channel complex
    • Nakatsuka A, Wada J, Iseda I, Teshigawara S, Higashio K, Murakami K, Kanzaki M, Inoue K, Terami T, Katayama A, et al: Visceral adipose tissue-derived serine proteinase inhibitor inhibits apoptosis of endothelial cells as a ligand for the cell-surface GRP78/voltage-dependent anion channel complex. Circ Res 112: 771-780, 2013.
    • (2013) Circ Res , vol.112 , pp. 771-780
    • Nakatsuka, A.1    Wada, J.2    Iseda, I.3    Teshigawara, S.4    Higashio, K.5    Murakami, K.6    Kanzaki, M.7    Inoue, K.8    Terami, T.9    Katayama, A.10
  • 13
    • 66349092815 scopus 로고    scopus 로고
    • Mechanisms and consequences of macrophage apoptosis in atherosclerosis
    • Seimon T and Tabas I: Mechanisms and consequences of macrophage apoptosis in atherosclerosis. J Lipid Res 50 (Suppl): S382-S387, 2009.
    • (2009) J Lipid Res , vol.50 , pp. S382-S387
    • Seimon, T.1    Tabas, I.2
  • 14
    • 84866318436 scopus 로고    scopus 로고
    • Macrophage proliferation and apoptosis in atherosclerosis
    • Andrés V, Pello OM and Silvestre-Roig C: Macrophage proliferation and apoptosis in atherosclerosis. Curr Opin Lipidol 23: 429-438, 2012.
    • (2012) Curr Opin Lipidol , vol.23 , pp. 429-438
    • Andrés, V.1    Pello, O.M.2    Silvestre-Roig, C.3
  • 15
    • 77950343252 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress and the inflammatory basis of metabolic disease
    • Hotamisligil GS: Endoplasmic reticulum stress and the inflammatory basis of metabolic disease. Cell 140: 900-917, 2010.
    • (2010) Cell , vol.140 , pp. 900-917
    • Hotamisligil, G.S.1
  • 16
    • 81755161377 scopus 로고    scopus 로고
    • Mechanisms of ER stress-induced apoptosis in atherosclerosis
    • Scull CM and Tabas I: Mechanisms of ER stress-induced apoptosis in atherosclerosis. Arterioscler Thromb Vasc Biol 31: 2792-2797, 2011.
    • (2011) Arterioscler Thromb Vasc Biol , vol.31 , pp. 2792-2797
    • Scull, C.M.1    Tabas, I.2
  • 19
    • 84884355814 scopus 로고    scopus 로고
    • Plasma vaspin concentrations are decreased in acute coronary syndrome, but unchanged in patients without coronary lesions
    • Zhang B, Peng W, Li H, Lu Y, Zhuang J, Wang K, Su Y and Xu Y: Plasma vaspin concentrations are decreased in acute coronary syndrome, but unchanged in patients without coronary lesions. Clin Biochem 46: 1520-1525, 2013.
    • (2013) Clin Biochem , vol.46 , pp. 1520-1525
    • Zhang, B.1    Peng, W.2    Li, H.3    Lu, Y.4    Zhuang, J.5    Wang, K.6    Su, Y.7    Xu, Y.8
  • 21
    • 84891940639 scopus 로고    scopus 로고
    • Inhibitory effects of vinpocetine on the progression of atherosclerosis are mediated by Akt/NF-kB dependent mechanisms in apoE-/-mice
    • Zhuang J, Peng W, Li H, Lu Y, Wang K, Fan F, Li S and Xu Y: Inhibitory effects of vinpocetine on the progression of atherosclerosis are mediated by Akt/NF-kB dependent mechanisms in apoE-/-mice. PloS One 8: e82509, 2013.
    • (2013) PloS One , vol.8 , pp. e82509
    • Zhuang, J.1    Peng, W.2    Li, H.3    Lu, Y.4    Wang, K.5    Fan, F.6    Li, S.7    Xu, Y.8
  • 22
    • 84863815675 scopus 로고    scopus 로고
    • A novel adipocytokine, vaspin inhibits platelet-derived growth factor-BB-induced migration of vascular smooth muscle cells
    • Phalitakul S, Okada M, Hara Y and Yamawaki H: A novel adipocytokine, vaspin inhibits platelet-derived growth factor-BB-induced migration of vascular smooth muscle cells. Biochem Biophys Res Commun 423: 844-849, 2012.
    • (2012) Biochem Biophys Res Commun , vol.423 , pp. 844-849
    • Phalitakul, S.1    Okada, M.2    Hara, Y.3    Yamawaki, H.4
  • 23
    • 80054995618 scopus 로고    scopus 로고
    • Vaspin prevents TNF-α-induced intracellular adhesion molecule-1 via inhibiting reactive oxygen species-dependent NF-κB and PKCθ activation in cultured rat vascular smooth muscle cells
    • Phalitakul S, Okada M, Hara Y and Yamawaki H: Vaspin prevents TNF-α-induced intracellular adhesion molecule-1 via inhibiting reactive oxygen species-dependent NF-κB and PKCθ activation in cultured rat vascular smooth muscle cells. Pharmacol Res 64: 493-500, 2011.
    • (2011) Pharmacol Res , vol.64 , pp. 493-500
    • Phalitakul, S.1    Okada, M.2    Hara, Y.3    Yamawaki, H.4
  • 24
    • 0036022403 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress-mediated apoptosis in pancreatic beta-cells
    • Oyadomari S, Araki E and Mori M: Endoplasmic reticulum stress-mediated apoptosis in pancreatic beta-cells. Apoptosis 7: 335-345, 2002.
    • (2002) Apoptosis , vol.7 , pp. 335-345
    • Oyadomari, S.1    Araki, E.2    Mori, M.3
  • 27
    • 17144419252 scopus 로고    scopus 로고
    • Activation of the unfolded protein response occurs at all stages of atherosclerotic lesion development in apolipoprotein E-deficient mice
    • Zhou J, Lhoták S, Hilditch BA and Austin RC: Activation of the unfolded protein response occurs at all stages of atherosclerotic lesion development in apolipoprotein E-deficient mice. Circulation 111: 1814-1821, 2005.
    • (2005) Circulation , vol.111 , pp. 1814-1821
    • Zhou, J.1    Lhoták, S.2    Hilditch, B.A.3    Austin, R.C.4
  • 28
    • 65349135431 scopus 로고    scopus 로고
    • Reduced apoptosis and plaque necrosis in advanced atherosclerotic lesions of Apoe-/-and Ldlr-/-mice lacking CHOP
    • Thorp E, Li G, Seimon TA, Kuriakose G, Ron D and Tabas I: Reduced apoptosis and plaque necrosis in advanced atherosclerotic lesions of Apoe-/-and Ldlr-/-mice lacking CHOP. Cell Metab 9: 474-481, 2009.
    • (2009) Cell Metab , vol.9 , pp. 474-481
    • Thorp, E.1    Li, G.2    Seimon, T.A.3    Kuriakose, G.4    Ron, D.5    Tabas, I.6
  • 29
    • 77957711395 scopus 로고    scopus 로고
    • The endoplasmic reticulum stress-C/EBP homologous protein pathway-mediated apoptosis in macrophages contributes to the instability of atherosclerotic plaques
    • Tsukano H, Gotoh T, Endo M, Miyata K, Tazume H, Kadomatsu T, Yano M, Iwawaki T, Kohno K, Araki K, et al: The endoplasmic reticulum stress-C/EBP homologous protein pathway-mediated apoptosis in macrophages contributes to the instability of atherosclerotic plaques. Arterioscler Thromb Vasc Biol 30: 1925-1932, 2010.
    • (2010) Arterioscler Thromb Vasc Biol , vol.30 , pp. 1925-1932
    • Tsukano, H.1    Gotoh, T.2    Endo, M.3    Miyata, K.4    Tazume, H.5    Kadomatsu, T.6    Yano, M.7    Iwawaki, T.8    Kohno, K.9    Araki, K.10
  • 30
    • 0037072937 scopus 로고    scopus 로고
    • An endoplasmic reticulum stress-specific caspase cascade in apoptosis. Cytochrome c-independent activation of caspase-9 by caspase-12
    • Morishima N, Nakanishi K, Takenouchi H, Shibata T and Yasuhiko Y: An endoplasmic reticulum stress-specific caspase cascade in apoptosis. Cytochrome c-independent activation of caspase-9 by caspase-12. J Biol Chem 277: 34287-34294, 2002.
    • (2002) J Biol Chem , vol.277 , pp. 34287-34294
    • Morishima, N.1    Nakanishi, K.2    Takenouchi, H.3    Shibata, T.4    Yasuhiko, Y.5
  • 31
    • 78349265743 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress as a therapeutic target in cardiovascular disease
    • Minamino T, Komuro I and Kitakaze M: Endoplasmic reticulum stress as a therapeutic target in cardiovascular disease. Circ Res 107: 1071-1082, 2010.
    • (2010) Circ Res , vol.107 , pp. 1071-1082
    • Minamino, T.1    Komuro, I.2    Kitakaze, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.