Associations of microbiota and toll-like receptor signaling pathway in esophageal adenocarcinoma

BMC Cancer

Volumn 16, Issue 1, 2016, Pages

  Zaidi, Ali H ^a   Kelly, Lori A ^a   Kreft, Rachael E ^a   Barlek, Mark ^a   Omstead, Ashten N ^a   Matsui, Daisuke ^a   Boyd, Natalie H ^a   Gazarik, Kathryn E ^a   Heit, Megan I ^a   Nistico, Laura ^a   Kasi, Pashtoon M ^b   Spirk, Tracy L ^a   Byers, Barbara ^a   Lloyd, Emily J ^a   Landreneau, Rodney J ^a   Jobe, Blair A ^a  

^a ALLEGHENY HEALTH NETWORK   (United States)

^b MAYO CLINIC   (United States)

Author keywords

Esophageal adenocarcinoma; Levrat model; Microbiota; Toll Like Receptors

Indexed keywords

TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 1; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 6; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 9;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BARRETT ESOPHAGUS; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; ESCHERICHIA COLI; ESOPHAGEAL ADENOCARCINOMA; ESOPHAGUS DYSPLASIA; ESOPHAGUS MUCOSA; FLUORESCENCE IN SITU HYBRIDIZATION; GASTROESOPHAGEAL REFLUX; GENE EXPRESSION; HUMAN; HUMAN TISSUE; MALE; MICROFLORA; NONHUMAN; POLYMERASE CHAIN REACTION; RAT; SIGNAL TRANSDUCTION; STREPTOCOCCUS PNEUMONIA; TIME OF FLIGHT MASS SPECTROMETRY; UPREGULATION; ADENOCARCINOMA; ANIMAL; BIOSYNTHESIS; CARCINOGENESIS; DISEASE MODEL; ESOPHAGUS TUMOR; GENE EXPRESSION REGULATION; GENETICS; ISOLATION AND PURIFICATION; MICROBIOLOGY; PATHOGENICITY; PATHOLOGY; STREPTOCOCCUS PNEUMONIAE;

ADENOCARCINOMA; ANIMALS; BARRETT ESOPHAGUS; CARCINOGENESIS; DISEASE MODELS, ANIMAL; ESCHERICHIA COLI; ESOPHAGEAL NEOPLASMS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; MICROBIOTA; RATS; SIGNAL TRANSDUCTION; STREPTOCOCCUS PNEUMONIAE; TOLL-LIKE RECEPTORS;

EID: 84956634619     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/s12885-016-2093-8     Document Type: Article

References (34)

1. Jemal A, Siegel R, Ward E, Hao Y, Xu J, Thun MJ. Cancer statistics. CA Cancer J Clin. 2009;59(4):225-49. doi: 10.3322/caac.20006.
2. Enzinger PC, Mayer RJ. Esophageal cancer. N Engl J Med. 2003;349(23):2241-52. doi: 10.1056/NEJMra035010.
3. Peterson LW, Artis D. Intestinal epithelial cells: regulators of barrier function and immune homeostasis. Nat Rev Immunol. 2014;14(3):141-53. doi: 10.1038/nri3608.
4. Asquith M, Powrie F. An innately dangerous balancing act: intestinal homeostasis, inflammation, and colitis-associated cancer. J Exp Med. 2010;207(8):1573-7. doi: 10.1084/jem.20101330.
5. Al-Haddad S, El-Zimaity H, Hafezi-Bakhtiari S, Rajendra S, Streutker CJ, Vajpeyi R, et al. Infection and esophageal cancer. Ann N Y Acad Sci. 2014;1325:187-96. doi: 10.1111/nyas.12530.
6. Blackett KL, Siddhi SS, Cleary S, Steed H, Miller MH, Macfarlane S, et al. Oesophageal bacterial biofilm changes in gastro-oesophageal reflux disease, Barrett's and oesophageal carcinoma: association or causality? Aliment Pharmacol Ther. 2013;37(11):1084-92. doi: 10.1111/apt.12317.
7. Amir I, Konikoff FM, Oppenheim M, Gophna U, Half EE. Gastric microbiota is altered in oesophagitis and Barrett's oesophagus and further modified by proton pump inhibitors. Environ Microbiol. 2014;16(9):2905-14. doi: 10.1111/1462-2920.12285.
8. Brawner KM, Morrow CD, Smith PD. Gastric microbiome and gastric cancer. Cancer J. 2014;20(3):211-6. doi: 10.1097/PPO.0000000000000043.
9. Amirian ES, Petrosino JF, Ajami NJ, Liu Y, Mims MP, Scheurer ME. Potential role of gastrointestinal microbiota composition in prostate cancer risk. Infectious Agents Cancer. 2013;8(1):42. doi: 10.1186/1750-9378-8-42.
10. Sears CL, Garrett WS. Microbes, microbiota, and colon cancer. Cell Host Microbe. 2014;15(3):317-28. doi: 10.1016/j.chom.2014.02.007.
11. Arthur JC, Jobin C. The complex interplay between inflammation, the microbiota and colorectal cancer. Gut Microbes. 2013;4(3):253-8. doi: 10.4161/gmic.24220.
12. Wagner H. Innate immunity's path to the Nobel Prize 2011 and beyond. Eur J Immunol. 2012;42(5):1089-92. doi: 10.1002/eji.201242404.
13. Medzhitov R, Preston-Hurlburt P, Janeway Jr CA. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature. 1997;388(6640):394-7. doi: 10.1038/41131.
14. Kumar H, Kawai T, Akira S. Toll-like receptors and innate immunity. Biochem Biophys Res Commun. 2009;388(4):621-5. doi: 10.1016/j.bbrc.2009.08.062.
15. Kawai T, Akira S. The roles of TLRs, RLRs and NLRs in pathogen recognition. Int Immunol. 2009;21(4):317-37. doi: 10.1093/intimm/dxp017.
16. Blasius AL, Beutler B. Intracellular toll-like receptors. Immunity. 2010;32(3):305-15. doi: 10.1016/j.immuni.2010.03.012.
17. Beutler B. Inferences, questions and possibilities in Toll-like receptor signalling. Nature. 2004;430(6996):257-63. doi: 10.1038/nature02761.
18. Thakur KK, Bolshette NB, Trandafir C, Jamdade VS, Istrate A, Gogoi R, et al. Role of toll-like receptors in multiple myeloma and recent advances. Exp Hematol. 2015;43(3):158-67. doi: 10.1016/j.exphem.2014.11.003.
19. Gibson MK, Zaidi AH, Davison JM, Sanz AF, Hough B, Komatsu Y, et al. Prevention of Barrett esophagus and esophageal adenocarcinoma by smoothened inhibitor in a rat model of gastroesophageal reflux disease. Ann Surg. 2013;258(1):82-8. doi: 10.1097/SLA.0b013e318270500d.
20. Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods. 2001;25(4):402-8. doi: 10.1006/meth.2001.1262.
21. Ecker DJ, Sampath R, Massire C, Blyn LB, Hall TA, Eshoo MW, et al. Ibis T5000: a universal biosensor approach for microbiology. Nat Rev Microbiol. 2008;6(7):553-8. doi: 10.1038/nrmicro1918.
22. Neef A, Amann R, Schleifer KH. Detection of microbial cells in aerosols using nucleic acid probes. Syst Appl Microbiol. 1995;18(1):113-22. doi: 10.1016/S0723-2020(11)80458-3.
23. Kempf VA, Trebesius K, Autenrieth IB. Fluorescent In situ hybridization allows rapid identification of microorganisms in blood cultures. J Clin Microbiol. 2000;38(2):830-8.
24. Kramer A, Green J, Pollard Jr J, Tugendreich S. Causal analysis approaches in ingenuity pathway analysis. Bioinformatics. 2014;30(4):523-30. doi: 10.1093/bioinformatics/btt703.
25. Adachi O, Kawai T, Takeda K, Matsumoto M, Tsutsui H, Sakagami M, et al. Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function. Immunity. 1998;9(1):143-50.
26. Kauppila JH, Selander KS. Toll-like receptors in esophageal cancer. Front Immunol. 2014;5:200. doi: 10.3389/fimmu.2014.00200.
27. Kauppila JH, Takala H, Selander KS, Lehenkari PP, Saarnio J, Karttunen TJ. Increased Toll-like receptor 9 expression indicates adverse prognosis in oesophageal adenocarcinoma. Histopathology. 2011;59(4):643-9. doi: 10.1111/j.1365-2559.2011.03991.x.
28. Lim DM, Narasimhan S, Michaylira CZ, Wang ML. TLR3-mediated NF-κB signaling in human esophageal epithelial cells. Am J Physiol Gastrointest Liver Physiol. 2009;297(6):G1172-80. doi: 10.1152/ajpgi.00065.2009.
29. Miyashita T, Shah FA, Miwa K, Sasaki S, Nishijima K, Oyama K, et al. Impact of inflammation-metaplasia-adenocarcinoma sequence and prevention in surgical rat models. Digestion. 2013;87(1):6-11. doi: 10.1159/000343896.
30. El-Mosalamy H, Salman TM, Ashmawey AM, Osama N. Role of chronic E. coli infection in the process of bladder cancer- an experimental study. Infectious Agents Cancer. 2012;7(1):19. doi: 10.1186/1750-9378-7-19.
31. Eppens EF, Nouwen N, Tommassen J. Folding of a bacterial outer membrane protein during passage through the periplasm. EMBO J. 1997;16(14):4295-301.
32. Caygill CJ, Gatenby PC. Epidemiology of the association between bacterial infections and cancer. In: Khan AA, editor. Bacteria and cancer. Netherlands: Springer; 2012. p. 1-24.
33. Narikiyo M, Tanabe C, Yamada Y, Igaki H, Tachimori Y, Kato H, et al. Frequent and preferential infection of Treponema denticola, Streptococcus mitis, and Streptococcus anginosus in esophageal cancers. Cancer Sci. 2004;95(7):569-74.
34. Yang L, Lu X, Nossa CW, Francois F, Peek RM, Pei Z. Inflammation and intestinal metaplasia of the distal esophagus are associated with alterations in the microbiome. Gastroenterology. 2009;137(2):588-97. doi: 10.1053/j.gastro.2009.04.046.