ASK1 inhibitor halts progression of diabetic nephropathy in Nos3-deficient mice

Diabetes

Volumn 64, Issue 11, 2015, Pages 3903-3913

  Tesch, Greg H ^a,b   Ma, Frank Y ^a,b   Han, Yingjie ^a,b   Liles, John T ^c   Breckenridge, David G ^c   Nikolic Paterson, David J ^a,b  

^a MONASH MEDICAL CENTRE   (Australia)

^b MONASH UNIVERSITY   (Australia)

^c GILEAD SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; APOPTOSIS SIGNAL REGULATING KINASE 1; CD6 ANTIGEN; COLLAGEN TYPE 4; CYSTATIN C; ENDOTHELIAL NITRIC OXIDE SYNTHASE; FIBRONECTIN; GLUCOSE; GS 444217; HEMOGLOBIN A1C; KIDNEY INJURY MOLECULE 1; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOCYTE CHEMOTACTIC PROTEIN 1; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEIN SERINE THREONINE KINASE INHIBITOR; RNA; STREPTOZOCIN; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG; URINARY TRACT AGENT; WT1 PROTEIN; ENZYME INHIBITOR;

ALBUMINURIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL LOSS; CONTROLLED STUDY; DIABETIC NEPHROPATHY; DISEASE COURSE; EARLY INTERVENTION; ENZYME INHIBITION; GLOMERULOSCLEROSIS; GLUCOSE BLOOD LEVEL; HYPERTENSION; IC50; IN VITRO STUDY; INSULIN DEPENDENT DIABETES MELLITUS; MACROPHAGE; MALE; MOUSE; NONHUMAN; PODOCYTE; PRIORITY JOURNAL; RENAL PROTECTION; SIGNAL TRANSDUCTION; SYSTOLIC BLOOD PRESSURE; ANIMAL; ANTAGONISTS AND INHIBITORS; BLOOD PRESSURE; DIABETIC NEPHROPATHIES; DRUG EFFECTS; EXPERIMENTAL DIABETES MELLITUS; GENETICS; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY;

ANIMALS; BLOOD PRESSURE; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC NEPHROPATHIES; DISEASE PROGRESSION; ENZYME INHIBITORS; MALE; MAP KINASE KINASE KINASE 5; MICE; MICE, KNOCKOUT; NITRIC OXIDE SYNTHASE TYPE III; SIGNAL TRANSDUCTION;

EID: 84956596940     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db15-0384     Document Type: Article

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