Critical role of apoptosis signal-regulating kinase 1 in aldosterone/salt-induced cardiac inflammation and fibrosis

Hypertension

Volumn 54, Issue 3, 2009, Pages 544-551

  Nakamura, Taishi ^a   Kataoka, Keiichiro ^a   Fukuda, Masaya ^a   Nako, Hisato ^a   Tokutomi, Yoshiko ^a   Dong, Yi Fei ^a   Ichijo, Hidenori ^b   Ogawa, Hisao ^a   Kim Mitsuyama, Shokei ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

Angiotensin; Cardiac injury; Cross talk; Inflammation; Oxidative stress

Indexed keywords

ALBUMIN; ALDOSTERONE; ANGIOTENSIN 1 RECEPTOR; APOPTOSIS SIGNAL REGULATING KINASE 1; COLLAGEN TYPE 1; DIPEPTIDYL CARBOXYPEPTIDASE; MONOCYTE CHEMOTACTIC PROTEIN 1; POTASSIUM; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; SODIUM CHLORIDE; TRANSFORMING GROWTH FACTOR BETA1; CCL2 PROTEIN, MOUSE; MAP3K5 PROTEIN, MOUSE; MITOGEN ACTIVATED PROTEIN KINASE; SODIUM; SUPEROXIDE;

ANIMAL EXPERIMENT; ARTICLE; BLOOD PRESSURE MONITORING; CARDITIS; CELL INFILTRATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; FIBROSING ALVEOLITIS; HEART INJURY; HEART MUSCLE FIBROSIS; HEART RATE; HEART VENTRICLE HYPERTROPHY; HYPERTENSION; IN VIVO CULTURE; KIDNEY INJURY; MACROPHAGE; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; POTASSIUM BLOOD LEVEL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR UPREGULATION; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SALT INTAKE; URINARY EXCRETION; ALBUMINURIA; ANIMAL; BLOOD; BLOOD PRESSURE; C57BL MOUSE; DRUG EFFECT; FEMALE; FIBROSIS; GENE EXPRESSION; GENETICS; HEART MUSCLE; INFLAMMATION; METABOLISM; MOUSE MUTANT; PATHOLOGY; URINE;

ALBUMINURIA; ALDOSTERONE; ANIMALS; BLOOD PRESSURE; CHEMOKINE CCL2; FEMALE; FIBROSIS; GENE EXPRESSION; INFLAMMATION; MACROPHAGES; MALE; MAP KINASE KINASE KINASE 5; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MITOGEN-ACTIVATED PROTEIN KINASES; MYOCARDIUM; NADPH OXIDASE; PEPTIDYL-DIPEPTIDASE A; POTASSIUM; RECEPTOR, ANGIOTENSIN, TYPE 1; SODIUM; SODIUM CHLORIDE, DIETARY; SUPEROXIDES; TRANSFORMING GROWTH FACTOR BETA1;

EID: 70349235614     PISSN: 0194911X     EISSN: None     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.109.135392     Document Type: Article

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