A Direct, Concise, and Enantioselective Synthesis of 2-Substituted 4,4,4-Trifluorobutane-1,3-diols Based on the Organocatalytic in Situ Generation of Unstable Trifluoroacetaldehyde

Chemistry - An Asian Journal

Volumn 10, Issue 12, 2015, Pages 2701-2707

  Funabiki, Kazumasa ^a   Furuno, Yudai ^a   Yano, Yosuke ^a   Sakaida, Yuta ^a   Kubota, Yasuhiro ^a   Matsui, Masaki ^a  

^a GIFU UNIVERSITY   (Japan)

Author keywords

aldol reaction; asymmetric synthesis; fluorine; organocatalysis; synthesis design

Indexed keywords

ALDEHYDES; CHEMICAL REACTIONS; CONDENSATION REACTIONS; DICHLOROMETHANE; FLUORINE; KETONES; SELECTIVE CATALYTIC REDUCTION;

ALDOL REACTIONS; ASYMMETRIC SYNTHESIS; DIASTEREOSELECTIVITIES; DIRECT ALDOL REACTION; ENANTIOSELECTIVE SYNTHESIS; ORGANOCATALYSIS; SYNTHESIS DESIGN; TRIFLUOROACETALDEHYDE;

ENANTIOSELECTIVITY;

3-HYDROXYBUTANAL; ACETALDEHYDE; ALDEHYDE; BORANE DERIVATIVE; BUTANEDIOL; DICHLOROMETHANE; KETONE; PROLINAMIDE; PROLINE; SODIUM BOROHYDRIDE; TRIFLUOROACETALDEHYDE;

ANALOGS AND DERIVATIVES; CATALYSIS; CHEMISTRY; OXIDATION REDUCTION REACTION; STEREOISOMERISM; SYNTHESIS;

ACETALDEHYDE; ALDEHYDES; BOROHYDRIDES; BUTYLENE GLYCOLS; CATALYSIS; KETONES; METHYLENE CHLORIDE; OXIDATION-REDUCTION; PROLINE; STEREOISOMERISM;

EID: 84956593718     PISSN: 18614728     EISSN: 1861471X     Source Type: Journal    
DOI: 10.1002/asia.201500607     Document Type: Article

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