Reversal of diastereoselectivity in reactions of the trifluoroacetaldehyde ethyl hemiacetal with enamines and imines: Metal-free, complementary anti-and syn-selective synthesis of 4,4,4-trifluoro-1-aryl-3-hydroxy-2-methyl-1-butanones

Journal of Organic Chemistry

Volumn 76, Issue 1, 2011, Pages 285-288

  Funabiki, Kazumasa ^a   Matsunaga, Kei ^a   Gonda, Hiroshi ^a   Yamamoto, Hitoshi ^a   Arima, Takao ^a   Kubota, Yasuhiro ^a   Matsui, Masaki ^a  

^a GIFU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DIASTEREO-SELECTIVITY; ENAMINES; HEMIACETALS; SELECTIVE SYNTHESIS; TRIFLUOROACETALDEHYDE;

AMINES; STEREOSELECTIVITY;

KETONES;

4,4,4 TRIFLUORO 1 ARYL 3 HYDROXY 2 METHYL 1 BUTANONE DERIVATIVE; ACETALDEHYDE; ENAMINE; IMINE; PROPIOPHENONE DERIVATIVE; UNCLASSIFIED DRUG;

ALDOL REACTION; ARTICLE; CHEMICAL REACTION; CHEMICAL STRUCTURE; DIASTEREOISOMER; HYDROGEN BOND; HYDROLYSIS; REACTION ANALYSIS; STEREOCHEMISTRY; SYNTHESIS;

ACETALDEHYDE; BIPHENYL COMPOUNDS; BUTANONES; CATALYSIS; IMIDAZOLES; IMINES; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; STEREOISOMERISM;

EID: 78650860332     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo101733j     Document Type: Article

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