Does metabolic syndrome impact cognition and emotion in Alzheimer's disease?

European Journal of Neurology

Volumn 23, Issue 2, 2016, Pages 237-238

  Willette, A ^a  

^a IOWA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER DISEASE; ANXIETY DISORDER; BRAIN ATROPHY; CALORIC RESTRICTION; COGNITION; COGNITIVE DEFECT; DEPRESSION; EDITORIAL; EMOTION; EXECUTIVE FUNCTION; EXECUTIVE FUNCTION TEST; GERIATRIC DEPRESSION SCALE; GLUCOSE METABOLISM; HUMAN; INSULIN RESISTANCE; LIFESPAN; MEMORY; METABOLIC SYNDROME X; NONHUMAN; OBESITY; PRIORITY JOURNAL; RISK FACTOR; VASCULAR ENDOTHELIUM; WAIST CIRCUMFERENCE; WHITE MATTER; PSYCHOLOGY;

ALZHEIMER DISEASE; COGNITION; COGNITION DISORDERS; EMOTIONS; HUMANS; METABOLIC SYNDROME X;

EID: 84956581803     PISSN: 13515101     EISSN: 14681331     Source Type: Journal    
DOI: 10.1111/ene.12879     Document Type: Editorial

References (9)

1. De Felice FG, Ferreira ST. Inflammation, defective insulin signaling, and mitochondrial dysfunction as common molecular denominators connecting type 2 diabetes to Alzheimer disease. Diabetes 2014; 63: 2262-2272.
2. Frisardi V, Solfrizzi V, Seripa D, et al. Metabolic-cognitive syndrome: a cross-talk between metabolic syndrome and Alzheimer's disease. Ageing Res Rev 2010; 9: 399-417.
3. Willette AA, Modanlo N, Kapogiannis D. Alzheimer's disease neuroimaging I. Insulin resistance predicts medial temporal hypermetabolism in mild cognitive impairment conversion to Alzheimer disease. Diabetes 2015; 64: 1933-1940.
4. van Dijk G, van Heijningen S, Reijne AC, Nyakas C, van der Zee EA, Eisel UL. Integrative neurobiology of metabolic diseases, neuroinflammation, and neurodegeneration. Front Neurosci 2015; 9: 173.
5. Willette AA, Bendlin BB, Starks EJ, et al. Association of insulin resistance with cerebral glucose uptake in late middle-aged adults at risk for Alzheimer disease. JAMA Neurol 2015; 72: 1013-1020.
6. Siervo M, Harrison SL, Jagger C, Robinson L, Stephan BC. Metabolic syndrome and longitudinal changes in cognitive function: a systematic review and meta-analysis. J Alzheimers Dis 2014; 41: 151-161.
7. Talbot K. Brain insulin resistance in Alzheimer's disease and its potential treatment with GLP-1 analogs. Neurodegener Dis Manag 2014; 4: 31-40.
8. Hishikawa N, Fukui Y, Sato K, et al. Cognitive and affective functions in Alzheimer's disease patients with metabolic syndrome. Eur J Neurol, 2016; 23: 339-345.
9. Willette AA, Kapogiannis D. Does the brain shrink as the waist expands? Ageing Res Rev 2015; 20: 86-97.