Cognitive and affective functions in Alzheimer's disease patients with metabolic syndrome

European Journal of Neurology

Volumn 23, Issue 2, 2016, Pages 339-345

  Hishikawa, N ^a   Fukui, Y ^a   Sato, K ^a   Kono, S ^a   Yamashita, T ^a   Ohta, Y ^a   Deguchi, K ^a   Abe, K ^a  

^a OKAYAMA UNIVERSITY   (Japan)

Author keywords

Alzheimer's disease; Cognitive affective functions; Insulin resistance; Metabolic syndrome; Vascular endothelial function; Vascular risk factors

Indexed keywords

AGED; ALZHEIMER DISEASE; ARTICLE; CLINICAL ASSESSMENT TOOL; COGNITION ASSESSMENT; CONTROLLED STUDY; FEMALE; FRONTAL ASSESSMENT BATTERY AND MONTREAL COGNITIVE ASSESSMENT; GERIATRIC DEPRESSION SCALE; HASEGAWA DEMENTIA SCORE REVISED; HOMEOSTASIS MODEL ASSESSMENT OF INSULIN RESISTANCE; HUMAN; INSULIN RESISTANCE; MAJOR CLINICAL STUDY; MALE; METABOLIC SYNDROME X; MINI MENTAL STATE EXAMINATION; MOOD DISORDER; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SCANNER; PRIORITY JOURNAL; REACTIVE HYPEREMIA INDEX SCORE; RETROSPECTIVE STUDY; RISK FACTOR; VASCULAR ENDOTHELIUM; WAIST CIRCUMFERENCE; WHITE MATTER; APATHY; COMORBIDITY; DEPRESSION; JAPAN; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; VERY ELDERLY;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; APATHY; COMORBIDITY; DEPRESSION; FEMALE; HUMANS; JAPAN; MALE; METABOLIC SYNDROME X; WHITE MATTER;

EID: 84956572611     PISSN: 13515101     EISSN: 14681331     Source Type: Journal    
DOI: 10.1111/ene.12845     Document Type: Article

References (19)

1. World Health Organization (WHO). The top 10 causes of death. http://www.who.int/mediacentre/factsheets/fs310/en/index.html (accessed May 2014).
2. Raffaitin C, Gin H, Empana JP, et al. Metabolic syndrome and risk for incident Alzheimer's disease or vascular dementia: the Three-City Study. Diabetes Care 2009; 32: 169-174.
3. Vanhanen M, Koivisto K, Moilanen L, et al. Association of metabolic syndrome with Alzheimer disease: a population-based study. Neurology 2006; 12: 843-847.
4. Deschaintre Y, Richard F, Leys D, Pasquier F. Treatment of vascular risk factors is associated with slower decline in Alzheimer disease. Neurology 2009; 1: 674-680.
5. Biessels GJ, Staekenborg S, Brunner E, Brayne C, Scheltens P. Risk of dementia in diabetes mellitus: a systematic review. Lancet Neurol 2006; 5: 64-74.
6. Ríos JA, Cisternas P, Arrese M, Barja S, Inestrosa NC. Is Alzheimer's disease related to metabolic syndrome? A Wnt signaling conundrum Prog Neurobiol 2014; 121: 125-146.
7. Willette AA, Johnson SC, Birdsill AC, et al. Insulin resistance predicts brain amyloid deposition in late middle-aged adults. Alzheimers Dement 2015; 11: 504-510.
8. Dunbar JA, Reddy P, Davis-Lameloise N, et al. Depression: an important comorbidity with metabolic syndrome in a general population. Diabetes Care 2008; 31: 2368-2373.
9. Roriz-Cruz M, Rosset I, Wada T, et al. Cognitive impairment and frontal-subcortical geriatric syndrome are associated with metabolic syndrome in a stroke-free population. Neurobiol Aging 2007; 28: 1723-1736.
10. McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology 1984; 34: 939-944.
11. Fukui Y, Yamashita T, Hishikawa N, et al. Computerized touch-panel screening tests for detecting mild cognitive impairment and Alzheimer's disease. Intern Med 2015; 54: 895-902.
12. Abe K, Yamashita T, Hishikawa N, et al. A new simple score (ABS) for assessing behavioral and psychological symptoms of dementia. J Neurol Sci 2015; 350: 14-17.
13. Yamada C, Mitsuhashi T, Hiratsuka N, Inabe F, Araida N, Takahashi E. Optimal reference interval for homeostasis model assessment of insulin resistance in a Japanese population. J Diabetes Investig 2011; 7: 373-376.
14. Fazekas F, Kleinert R, Offenbacher H, et al. The morphologic correlate of incidental punctate white matter hyperintensities on MR images. AJNR Am J Neuroradiol 1991; 12: 915-921.
15. Forti P, Pisacane N, Rietti E, et al. Metabolic syndrome and risk of dementia in older adults. J Am Geriatr Soc 2010; 58: 487-492.
16. Willette AA, Xu G, Johnson SC, et al. Insulin resistance, brain atrophy, and cognitive performance in late middle-aged adults. Diabetes Care 2013; 36: 443-449.
17. Skilton MR, Moulin P, Terra JL, Bonnet F. Associations between anxiety, depression, and the metabolic syndrome. Biol Psychiatry 2007; 62: 1251-1257.
18. Capuron L, Su S, Miller AH, et al. Depressive symptoms and metabolic syndrome: is inflammation the underlying link? Biol Psychiatry 2008; 64: 896-900.
19. Luppino FS, van Reedt Dortland AK, Wardenaar KJ, et al. Symptom dimensions of depression and anxiety and the metabolic syndrome. Psychosom Med 2011; 73: 257-264.