An Improved System for the Aqueous Lipshutz-Negishi Cross-Coupling of Alkyl Halides with Aryl Electrophiles

Angewandte Chemie - International Edition

Volumn 55, Issue 5, 2016, Pages 1849-1853

  Bhonde, Vasudev R ^a   O'Neill, Brian T ^b   Buchwald, Stephen L ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b PFIZER INC   (United States)

Author keywords

alkyl zinc reagents; cross coupling; micelles; palladium precatalysts; surfactants

Indexed keywords

FATTY ACIDS; LIGANDS; MICELLES; PHOSPHORUS COMPOUNDS; SCAFFOLDS; SURFACE ACTIVE AGENTS; ZINC;

ARYL ELECTROPHILES; CROSS-COUPLINGS; NEGISHI CROSS-COUPLING; PHOSPHINE LIGANDS; PRECATALYSTS; RAPID CONSTRUCTION; SURFACTANT SYSTEM; ZINC REAGENTS;

CHEMICAL REACTIONS;

HALOGEN; WATER;

HALOGENS; WATER;

EID: 84955667004     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201509341     Document Type: Article

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