메뉴 건너뛰기




Volumn 64, Issue 1, 2016, Pages 25-35

Natural killer cell receptors: alterations and therapeutic targeting in malignancies

Author keywords

Cancer immunotherapy; NK cell inhibitory and activating receptors; NK cells

Indexed keywords

C TYPE LECTIN HETERODIMER RECEPTOR; CD16 ANTIGEN; CD161 ANTIGEN; CELL RECEPTOR; DNAX ACCESSORY MOLECULE 1; IMMUNOGLOBULIN LIKE TRANSCRIPT; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR; LEUKOCYTE IMMUNOGLOBULIN LIKE RECEPTOR; NATURAL CYTOTOXIC RECEPTOR; NATURAL KILLER CELL RECEPTOR; NATURAL KILLER CELL RECEPTOR NKG2D; NATURAL KILLER RECEPTOR P1; UNCLASSIFIED DRUG; HLA ANTIGEN;

EID: 84955656324     PISSN: 0257277X     EISSN: 15590755     Source Type: Journal    
DOI: 10.1007/s12026-015-8695-4     Document Type: Review
Times cited : (32)

References (110)
  • 1
    • 50949124847 scopus 로고    scopus 로고
    • Human natural killer cells
    • PID: 18650461
    • Caligiuri MA. Human natural killer cells. Blood. 2008;112(3):461–9.
    • (2008) Blood , vol.112 , Issue.3 , pp. 461-469
    • Caligiuri, M.A.1
  • 2
    • 84921444124 scopus 로고    scopus 로고
    • Innate lymphoid cells: new insights into function and development
    • PID: 25615701
    • Cortez VS, Robinette ML, Colonna M. Innate lymphoid cells: new insights into function and development. Curr Opin Immunol. 2015;32:71–7.
    • (2015) Curr Opin Immunol , vol.32 , pp. 71-77
    • Cortez, V.S.1    Robinette, M.L.2    Colonna, M.3
  • 5
    • 84865977956 scopus 로고    scopus 로고
    • When NK cells overcome their lack of education
    • PID: 22863616
    • Jaeger BN, Vivier E. When NK cells overcome their lack of education. J Clin Invest. 2012;122(9):3053–6.
    • (2012) J Clin Invest , vol.122 , Issue.9 , pp. 3053-3056
    • Jaeger, B.N.1    Vivier, E.2
  • 6
    • 84880919946 scopus 로고    scopus 로고
    • Shaping of NK cell responses by the tumor microenvironment
    • PID: 23242671
    • Stojanovic A, Correia MP, Cerwenka A. Shaping of NK cell responses by the tumor microenvironment. Cancer Microenviron. 2013;6(2):135–46.
    • (2013) Cancer Microenviron , vol.6 , Issue.2 , pp. 135-146
    • Stojanovic, A.1    Correia, M.P.2    Cerwenka, A.3
  • 7
    • 77957230535 scopus 로고    scopus 로고
    • Current perspectives of natural killer cell education by MHC class I molecules
    • PID: 20818413
    • Höglund P, Brodin P. Current perspectives of natural killer cell education by MHC class I molecules. Nat Rev Immunol. 2010;10(10):724–34.
    • (2010) Nat Rev Immunol , vol.10 , Issue.10 , pp. 724-734
    • Höglund, P.1    Brodin, P.2
  • 8
    • 33646877669 scopus 로고    scopus 로고
    • Human natural killer cell development and biology
    • PID: 16364519
    • Farag SS, Caligiuri MA. Human natural killer cell development and biology. Blood Rev. 2006;20(3):123–37.
    • (2006) Blood Rev , vol.20 , Issue.3 , pp. 123-137
    • Farag, S.S.1    Caligiuri, M.A.2
  • 9
    • 79251631976 scopus 로고    scopus 로고
    • Structure/function of human killer cell immunoglobulin-like receptors: lessons from polymorphisms, evolution, crystal structures and mutations
    • PID: 21214544
    • Campbell KS, Purdy AK. Structure/function of human killer cell immunoglobulin-like receptors: lessons from polymorphisms, evolution, crystal structures and mutations. Immunology. 2011;132(3):315–25.
    • (2011) Immunology , vol.132 , Issue.3 , pp. 315-325
    • Campbell, K.S.1    Purdy, A.K.2
  • 12
    • 0020679842 scopus 로고
    • Assembly of two types of tubules with putative cytolytic function by cloned natural killer cells
    • PID: 6835377
    • Podack ER, Dennert G. Assembly of two types of tubules with putative cytolytic function by cloned natural killer cells. Nature. 1983;302(5907):442–5.
    • (1983) Nature , vol.302 , Issue.5907 , pp. 442-445
    • Podack, E.R.1    Dennert, G.2
  • 13
    • 0032212719 scopus 로고    scopus 로고
    • Depletion of the natural killer cell population in the peritoneum by AK-5 tumor cell overexpressing fas-ligand: a mechanism of immune evasion
    • PID: 9790721
    • Khar A, Varalakshmi C, Pardhasaradhi BV, Mubarak Ali A, Kumari AL. Depletion of the natural killer cell population in the peritoneum by AK-5 tumor cell overexpressing fas-ligand: a mechanism of immune evasion. Cell Immunol. 1998;189(2):85–91.
    • (1998) Cell Immunol , vol.189 , Issue.2 , pp. 85-91
    • Khar, A.1    Varalakshmi, C.2    Pardhasaradhi, B.V.3    Mubarak Ali, A.4    Kumari, A.L.5
  • 16
    • 79953840956 scopus 로고    scopus 로고
    • Confinement of activating receptors at the plasma membrane controls natural killer cell tolerance
    • PID: 21467299
    • Guia S, Jaeger BN, Piatek S, Mailfert S, Trombik T, Fenis A, Chevrier N, et al. Confinement of activating receptors at the plasma membrane controls natural killer cell tolerance. Sci Signal. 2011;4(167):ra21.
    • (2011) Sci Signal , vol.4 , Issue.167 , pp. ra21
    • Guia, S.1    Jaeger, B.N.2    Piatek, S.3    Mailfert, S.4    Trombik, T.5    Fenis, A.6    Chevrier, N.7
  • 17
    • 73949138990 scopus 로고    scopus 로고
    • Natural killer cells and cancer: regulation by the killer cell Ig-like receptors (KIR)
    • PID: 19923897
    • Purdy AK, Campbell KS. Natural killer cells and cancer: regulation by the killer cell Ig-like receptors (KIR). Cancer Biol Ther. 2009;8(32):2211–20.
    • (2009) Cancer Biol Ther , vol.8 , Issue.32 , pp. 2211-2220
    • Purdy, A.K.1    Campbell, K.S.2
  • 18
    • 34250158132 scopus 로고    scopus 로고
    • Natural killer cells, killer immunoglobulin-like receptors and human leucocyte antigen class I in disease
    • PID: 17521317
    • Boyton RJ, Altmann DM. Natural killer cells, killer immunoglobulin-like receptors and human leucocyte antigen class I in disease. Clin Exp Immunol. 2007;149(1):1–8.
    • (2007) Clin Exp Immunol , vol.149 , Issue.1 , pp. 1-8
    • Boyton, R.J.1    Altmann, D.M.2
  • 19
    • 33751362114 scopus 로고    scopus 로고
    • Impact of KIR/HLA ligand combinations on immune responses in malignant melanoma
    • PID: 16547704
    • Naumova E, Mihaylova A, Ivanova M, Mihailova S. Impact of KIR/HLA ligand combinations on immune responses in malignant melanoma. Cancer Immunol Immunother. 2007;56(1):95–100.
    • (2007) Cancer Immunol Immunother , vol.56 , Issue.1 , pp. 95-100
    • Naumova, E.1    Mihaylova, A.2    Ivanova, M.3    Mihailova, S.4
  • 20
    • 33748352566 scopus 로고    scopus 로고
    • Natural killer receptors on CD8 T cells and natural killer cells from different HLA-C phenotypes in melanoma patients
    • PID: 16914567
    • Campillo JA, Martínez-Escribano JA, Moya-Quiles MR, Marín LA, Muro M, Guerra N, Parrado A, et al. Natural killer receptors on CD8 T cells and natural killer cells from different HLA-C phenotypes in melanoma patients. Clin Cancer Res. 2006;12(16):4822–31.
    • (2006) Clin Cancer Res , vol.12 , Issue.16 , pp. 4822-4831
    • Campillo, J.A.1    Martínez-Escribano, J.A.2    Moya-Quiles, M.R.3    Marín, L.A.4    Muro, M.5    Guerra, N.6    Parrado, A.7
  • 21
    • 84885514189 scopus 로고    scopus 로고
    • Comprehensive analysis of the percentage of surface receptors and cytotoxic granules positive natural killer cells in patients with pancreatic cancer, gastric cancer, and colorectal cancer
    • PID: 24138752
    • Peng YP, Zhu Y, Zhang JJ, Xu ZK, Qian ZY, Dai CC, Jiang KR, et al. Comprehensive analysis of the percentage of surface receptors and cytotoxic granules positive natural killer cells in patients with pancreatic cancer, gastric cancer, and colorectal cancer. J Transl Med. 2013;11:262.
    • (2013) J Transl Med , vol.11 , pp. 262
    • Peng, Y.P.1    Zhu, Y.2    Zhang, J.J.3    Xu, Z.K.4    Qian, Z.Y.5    Dai, C.C.6    Jiang, K.R.7
  • 23
    • 33947606520 scopus 로고    scopus 로고
    • Impaired natural killer cell lysis in breast cancer patients with high levels of psychological stress is associated with altered expression of killer immunoglobulin-like receptors
    • PID: 17292412
    • Varker KA, Terrell CE, Welt M, Suleiman S, Thornton L, Andersen BL, Carson WE 3rd. Impaired natural killer cell lysis in breast cancer patients with high levels of psychological stress is associated with altered expression of killer immunoglobulin-like receptors. J Surg Res. 2007;139(1):36–44.
    • (2007) J Surg Res , vol.139 , Issue.1 , pp. 36-44
    • Varker, K.A.1    Terrell, C.E.2    Welt, M.3    Suleiman, S.4    Thornton, L.5    Andersen, B.L.6    Carson, W.E.7
  • 24
    • 79953300281 scopus 로고    scopus 로고
    • Increased killer immunoglobulin-like receptor expression and functional defects in natural killer cells in lung cancer
    • PID: 21342183
    • Al Omar SY, Marshall E, Middleton D, Christmas SE. Increased killer immunoglobulin-like receptor expression and functional defects in natural killer cells in lung cancer. Immunology. 2011;133(1):94–104.
    • (2011) Immunology , vol.133 , Issue.1 , pp. 94-104
    • Al Omar, S.Y.1    Marshall, E.2    Middleton, D.3    Christmas, S.E.4
  • 25
    • 81155133365 scopus 로고    scopus 로고
    • The stage dependent changes in NK cell activity and the expression of activating and inhibitory NK cell receptors in melanoma patients
    • PID: 20828749
    • Mirjačić Martinović K, Konjević G, Babović N, Inić M. The stage dependent changes in NK cell activity and the expression of activating and inhibitory NK cell receptors in melanoma patients. J Surg Res. 2011;171(2):637–49.
    • (2011) J Surg Res , vol.171 , Issue.2 , pp. 637-649
    • Mirjačić Martinović, K.1    Konjević, G.2    Babović, N.3    Inić, M.4
  • 26
    • 84880307201 scopus 로고    scopus 로고
    • Distribution of several activating and inhibitory receptors on CD3(−)CD56(+) NK cells in regional lymph nodes of melanoma patients
    • PID: 23522458
    • Vuletić A, Jurišić V, Jovanić I, Milovanović Z, Nikolić S, Konjević G. Distribution of several activating and inhibitory receptors on CD3(−)CD56(+) NK cells in regional lymph nodes of melanoma patients. J Surg Res. 2013;183(2):860–8.
    • (2013) J Surg Res , vol.183 , Issue.2 , pp. 860-868
    • Vuletić, A.1    Jurišić, V.2    Jovanić, I.3    Milovanović, Z.4    Nikolić, S.5    Konjević, G.6
  • 27
    • 68249091118 scopus 로고    scopus 로고
    • An integrated view of the regulation of NKG2D ligands
    • PID: 19689730
    • Stern-Ginossar N, Mandelboim O. An integrated view of the regulation of NKG2D ligands. Immunology. 2009;128(1):1–6.
    • (2009) Immunology , vol.128 , Issue.1 , pp. 1-6
    • Stern-Ginossar, N.1    Mandelboim, O.2
  • 29
    • 80054717670 scopus 로고    scopus 로고
    • Regulation of immune cell function and differentiation by the NKG2D receptor
    • PID: 21898152
    • Zafirova B, Wensveen FM, Gulin M, Polić B. Regulation of immune cell function and differentiation by the NKG2D receptor. Cell Mol Life Sci. 2011;68(21):3519–29.
    • (2011) Cell Mol Life Sci , vol.68 , Issue.21 , pp. 3519-3529
    • Zafirova, B.1    Wensveen, F.M.2    Gulin, M.3    Polić, B.4
  • 31
    • 33744533959 scopus 로고    scopus 로고
    • NKG2D and cytotoxic effector function in tumor immune surveillance
    • PID: 16675266
    • Hayakawa Y, Smyth MJ. NKG2D and cytotoxic effector function in tumor immune surveillance. Semin Immunol. 2006;18:176–85.
    • (2006) Semin Immunol , vol.18 , pp. 176-185
    • Hayakawa, Y.1    Smyth, M.J.2
  • 32
    • 80155132470 scopus 로고    scopus 로고
    • Human breast tumor cells induce self-tolerance mechanisms to avoid NKG2D-mediated and DNAM-mediated NK cell recognition
    • PID: 21937679
    • Mamessier E, Sylvain A, Bertucci F, Castellano R, Finetti P, Houvenaeghel G, Charaffe-Jaufret E, et al. Human breast tumor cells induce self-tolerance mechanisms to avoid NKG2D-mediated and DNAM-mediated NK cell recognition. Cancer Res. 2011;71(21):6621–32.
    • (2011) Cancer Res , vol.71 , Issue.21 , pp. 6621-6632
    • Mamessier, E.1    Sylvain, A.2    Bertucci, F.3    Castellano, R.4    Finetti, P.5    Houvenaeghel, G.6    Charaffe-Jaufret, E.7
  • 34
    • 84855870151 scopus 로고    scopus 로고
    • NKG2D ligand tumor expression and association with clinical outcome in early breast cancer patients: an observational study
    • PID: 22257486
    • de Kruijf EM, Sajet A, van Nes JG, Putter H, Smit VT, Eagle RA, Jafferji I, et al. NKG2D ligand tumor expression and association with clinical outcome in early breast cancer patients: an observational study. BMC Cancer. 2012;12:24.
    • (2012) BMC Cancer , vol.12 , pp. 24
    • de Kruijf, E.M.1    Sajet, A.2    van Nes, J.G.3    Putter, H.4    Smit, V.T.5    Eagle, R.A.6    Jafferji, I.7
  • 35
    • 84863355681 scopus 로고    scopus 로고
    • Possible association of decreased NKG2D expression levels and suppression of the activity of natural killer cells in patients with colorectal cancer
    • PID: 22200673
    • Shen Y, Lu C, Tian W, Wang L, Cui B, Jiao Y, Ma C. Possible association of decreased NKG2D expression levels and suppression of the activity of natural killer cells in patients with colorectal cancer. Int J Oncol. 2012;40(4):1285–90.
    • (2012) Int J Oncol , vol.40 , Issue.4 , pp. 1285-1290
    • Shen, Y.1    Lu, C.2    Tian, W.3    Wang, L.4    Cui, B.5    Jiao, Y.6    Ma, C.7
  • 36
    • 84881288707 scopus 로고    scopus 로고
    • Enhanced interaction between natural killer cells and lung cancer cells: involvement in gefitinib-mediated immunoregulation
    • PID: 23937717
    • He S, Yin T, Li D, Gao X, Wan Y, Ma X, Ye T, et al. Enhanced interaction between natural killer cells and lung cancer cells: involvement in gefitinib-mediated immunoregulation. J Transl Med. 2013;11:186.
    • (2013) J Transl Med , vol.11 , pp. 186
    • He, S.1    Yin, T.2    Li, D.3    Gao, X.4    Wan, Y.5    Ma, X.6    Ye, T.7
  • 37
    • 84859928040 scopus 로고    scopus 로고
    • Identification and functional analysis of ligands for natural killer cell activating receptors in colon carcinoma
    • PID: 22189020
    • Zhang Z, Su T, He L, Wang H, Ji G, Liu X, Zhang Y, Dong G. Identification and functional analysis of ligands for natural killer cell activating receptors in colon carcinoma. Tohoku J Exp Med. 2012;226(1):59–68.
    • (2012) Tohoku J Exp Med , vol.226 , Issue.1 , pp. 59-68
    • Zhang, Z.1    Su, T.2    He, L.3    Wang, H.4    Ji, G.5    Liu, X.6    Zhang, Y.7    Dong, G.8
  • 38
    • 84885701721 scopus 로고    scopus 로고
    • The tumor microenvironment: a pitch for multiple players
    • PID: 23616948
    • Schiavoni G, Gabriele L, Mattei F. The tumor microenvironment: a pitch for multiple players. Front Oncol. 2013;3:90.
    • (2013) Front Oncol , vol.3 , pp. 90
    • Schiavoni, G.1    Gabriele, L.2    Mattei, F.3
  • 39
    • 84880683894 scopus 로고    scopus 로고
    • Generation of soluble NKG2D ligands: proteolytic cleavage, exosome secretion and functional implications
    • PID: 23679194
    • Chitadze G, Bhat J, Lettau M, Janssen O, Kabelitz D. Generation of soluble NKG2D ligands: proteolytic cleavage, exosome secretion and functional implications. Scand J Immunol. 2013;78(2):120–9.
    • (2013) Scand J Immunol , vol.78 , Issue.2 , pp. 120-129
    • Chitadze, G.1    Bhat, J.2    Lettau, M.3    Janssen, O.4    Kabelitz, D.5
  • 41
    • 34147177669 scopus 로고    scopus 로고
    • Low expression of CD161 and NKG2D activating NK receptor is associated with impaired NK cell cytotoxicity in metastatic melanoma patients
    • PID: 17295095
    • Konjević G, Mirjacić Martinović K, Vuletić A, Jović V, Jurisić V, Babović N, Spuzić I. Low expression of CD161 and NKG2D activating NK receptor is associated with impaired NK cell cytotoxicity in metastatic melanoma patients. Clin Exp Metastasis. 2007;24(1):1–11.
    • (2007) Clin Exp Metastasis , vol.24 , Issue.1 , pp. 1-11
    • Konjević, G.1    Mirjacić Martinović, K.2    Vuletić, A.3    Jović, V.4    Jurisić, V.5    Babović, N.6    Spuzić, I.7
  • 42
    • 79958118266 scopus 로고    scopus 로고
    • Alternatively spliced NKp30 isoforms affect the prognosis of gastrointestinal stromal tumors
    • PID: 21552268
    • Delahaye NF, Rusakiewicz S, Martins I, Menard C, Roux S, Lyonnet L, Paul P, et al. Alternatively spliced NKp30 isoforms affect the prognosis of gastrointestinal stromal tumors. Nat Med. 2011;17(6):700–7.
    • (2011) Nat Med , vol.17 , Issue.6 , pp. 700-707
    • Delahaye, N.F.1    Rusakiewicz, S.2    Martins, I.3    Menard, C.4    Roux, S.5    Lyonnet, L.6    Paul, P.7
  • 43
    • 84856076551 scopus 로고    scopus 로고
    • Tuning of natural killer cell reactivity by NKp46 and Helios calibrates T cell responses
    • PID: 22267813
    • Narni-Mancinelli E, Jaeger BN, Bernat C, Fenis A, Kung S, De Gassart A, Mahmood S, et al. Tuning of natural killer cell reactivity by NKp46 and Helios calibrates T cell responses. Science. 2012;335(6066):344–8.
    • (2012) Science , vol.335 , Issue.6066 , pp. 344-348
    • Narni-Mancinelli, E.1    Jaeger, B.N.2    Bernat, C.3    Fenis, A.4    Kung, S.5    De Gassart, A.6    Mahmood, S.7
  • 44
    • 82755186747 scopus 로고    scopus 로고
    • Proliferating cell nuclear antigen is a novel inhibitory ligand for the natural cytotoxicity receptor NKp44
    • PID: 22021614
    • Rosental B, Brusilovsky M, Hadad U, Oz D, Appel MY, Afergan F, Yossef R, et al. Proliferating cell nuclear antigen is a novel inhibitory ligand for the natural cytotoxicity receptor NKp44. J Immunol. 2011;187(11):5693–702.
    • (2011) J Immunol , vol.187 , Issue.11 , pp. 5693-5702
    • Rosental, B.1    Brusilovsky, M.2    Hadad, U.3    Oz, D.4    Appel, M.Y.5    Afergan, F.6    Yossef, R.7
  • 45
    • 84877044329 scopus 로고    scopus 로고
    • Natural cytotoxicity receptors: broader expression patterns and functions in innate and adaptive immune cells
    • PID: 23518691
    • Hudspeth K, Silva-Santos B, Mavilio D. Natural cytotoxicity receptors: broader expression patterns and functions in innate and adaptive immune cells. Front Immunol. 2013;4:69.
    • (2013) Front Immunol , vol.4 , pp. 69
    • Hudspeth, K.1    Silva-Santos, B.2    Mavilio, D.3
  • 46
    • 84858202941 scopus 로고    scopus 로고
    • Melanoma cells inhibit natural killer cell function by modulating the expression of activating receptors and cytolytic activity
    • PID: 22258454
    • Pietra G, Manzini C, Rivara S, Vitale M, Cantoni C, Petretto A, Balsamo M, et al. Melanoma cells inhibit natural killer cell function by modulating the expression of activating receptors and cytolytic activity. Cancer Res. 2012;72(6):1407–15.
    • (2012) Cancer Res , vol.72 , Issue.6 , pp. 1407-1415
    • Pietra, G.1    Manzini, C.2    Rivara, S.3    Vitale, M.4    Cantoni, C.5    Petretto, A.6    Balsamo, M.7
  • 47
    • 84885413182 scopus 로고    scopus 로고
    • Downregulation of the activating NKp30 ligand B7–H6 by HDAC inhibitors impairs tumor cell recognition by NK cells
    • PID: 23801635
    • Fiegler N, Textor S, Arnold A, Rölle A, Oehme I, Breuhahn K, Moldenhauer G, et al. Downregulation of the activating NKp30 ligand B7–H6 by HDAC inhibitors impairs tumor cell recognition by NK cells. Blood. 2013;122(5):684–93.
    • (2013) Blood , vol.122 , Issue.5 , pp. 684-693
    • Fiegler, N.1    Textor, S.2    Arnold, A.3    Rölle, A.4    Oehme, I.5    Breuhahn, K.6    Moldenhauer, G.7
  • 48
    • 84879716313 scopus 로고    scopus 로고
    • Soluble ligands for NK cell receptors promote evasion of chronic lymphocytic leukemia cells from NK cell anti-tumor activity
    • PID: 23509156
    • Reiners KS, Topolar D, Henke A, Simhadri VR, Kessler J, Sauer M, Bessler M, et al. Soluble ligands for NK cell receptors promote evasion of chronic lymphocytic leukemia cells from NK cell anti-tumor activity. Blood. 2013;121(18):3658–65.
    • (2013) Blood , vol.121 , Issue.18 , pp. 3658-3665
    • Reiners, K.S.1    Topolar, D.2    Henke, A.3    Simhadri, V.R.4    Kessler, J.5    Sauer, M.6    Bessler, M.7
  • 50
    • 84881267413 scopus 로고    scopus 로고
    • A novel mechanism for cancer cells to evade immune attack by NK cells: the interaction between NKp44 and proliferating cell nuclear antigen
    • PID: 22754791
    • Rosental B, Hadad U, Brusilovsky M, Campbell KS, Porgador A. A novel mechanism for cancer cells to evade immune attack by NK cells: the interaction between NKp44 and proliferating cell nuclear antigen. Oncoimmunology. 2012;1(4):572–4.
    • (2012) Oncoimmunology , vol.1 , Issue.4 , pp. 572-574
    • Rosental, B.1    Hadad, U.2    Brusilovsky, M.3    Campbell, K.S.4    Porgador, A.5
  • 52
    • 66449134616 scopus 로고    scopus 로고
    • NCRs and DNAM-1 mediate NK cell recognition and lysis of human and mouse melanoma cell lines in vitro and in vivo
    • PID: 19349689
    • Lakshmikanth T, Burke S, Ali TH, Kimpfler S, Ursini F, Ruggeri L, Capanni M, et al. NCRs and DNAM-1 mediate NK cell recognition and lysis of human and mouse melanoma cell lines in vitro and in vivo. J Clin Invest. 2009;119(5):1251–63.
    • (2009) J Clin Invest , vol.119 , Issue.5 , pp. 1251-1263
    • Lakshmikanth, T.1    Burke, S.2    Ali, T.H.3    Kimpfler, S.4    Ursini, F.5    Ruggeri, L.6    Capanni, M.7
  • 53
    • 79959658972 scopus 로고    scopus 로고
    • NK cell recognition and killing of melanoma cells is controlled by multiple activating receptor-ligand interactions
    • PID: 21576932
    • Morgado S, Sanchez-Correa B, Casado JG, Duran E, Gayoso I, Labella F, Solana R, Tarazona R. NK cell recognition and killing of melanoma cells is controlled by multiple activating receptor-ligand interactions. J Innate Immun. 2011;3(4):365–73.
    • (2011) J Innate Immun , vol.3 , Issue.4 , pp. 365-373
    • Morgado, S.1    Sanchez-Correa, B.2    Casado, J.G.3    Duran, E.4    Gayoso, I.5    Labella, F.6    Solana, R.7    Tarazona, R.8
  • 54
    • 33344469008 scopus 로고    scopus 로고
    • Expression of the DNAM-1 ligands, Nectin-2 (CD112) and poliovirus receptor (CD155), on dendritic cells: relevance for natural killer-dendritic cell interaction
    • PID: 16304049
    • Pende D, Castriconi R, Romagnani P, Spaggiari GM, Marcenaro S, Dondero A, Lazzeri E, et al. Expression of the DNAM-1 ligands, Nectin-2 (CD112) and poliovirus receptor (CD155), on dendritic cells: relevance for natural killer-dendritic cell interaction. Blood. 2006;107(5):2030–6.
    • (2006) Blood , vol.107 , Issue.5 , pp. 2030-2036
    • Pende, D.1    Castriconi, R.2    Romagnani, P.3    Spaggiari, G.M.4    Marcenaro, S.5    Dondero, A.6    Lazzeri, E.7
  • 55
    • 84864530880 scopus 로고    scopus 로고
    • Cancer immunotherapy using NKG2D and DNAM-1 systems
    • PID: 22641658
    • Morisaki T, Onishi H, Katano M. Cancer immunotherapy using NKG2D and DNAM-1 systems. Anticancer Res. 2012;32(6):2241–7.
    • (2012) Anticancer Res , vol.32 , Issue.6 , pp. 2241-2247
    • Morisaki, T.1    Onishi, H.2    Katano, M.3
  • 56
    • 84904036773 scopus 로고    scopus 로고
    • Decreased expression of NKG2D, NKp46, DNAM-1 receptors, and intracellular perforin and STAT-1 effector molecules in NK cells and their dim and bright subsets in metastatic melanoma patients
    • PID: 24769842
    • Mirjačić Martinović KM, Babović NLJ, Džodić RR, Jurišić VB, Tanić NT, Konjević GM. Decreased expression of NKG2D, NKp46, DNAM-1 receptors, and intracellular perforin and STAT-1 effector molecules in NK cells and their dim and bright subsets in metastatic melanoma patients. Melanoma Res. 2014;24(4):295–304.
    • (2014) Melanoma Res , vol.24 , Issue.4 , pp. 295-304
    • Mirjačić Martinović, K.M.1    Babović, N.L.J.2    Džodić, R.R.3    Jurišić, V.B.4    Tanić, N.T.5    Konjević, G.M.6
  • 57
    • 0033555891 scopus 로고    scopus 로고
    • Quantitative analysis of the effect of CD16 ligation on human NK cell proliferation
    • PID: 9916693
    • Warren HS, Kinnear BF. Quantitative analysis of the effect of CD16 ligation on human NK cell proliferation. J Immunol. 1999;162(2):735–42.
    • (1999) J Immunol , vol.162 , Issue.2 , pp. 735-742
    • Warren, H.S.1    Kinnear, B.F.2
  • 58
    • 0024391085 scopus 로고
    • Comparative studies of human FcRIII-positive and negative natural killer cells
    • PID: 2530273
    • Nagler A, Lanier LL, Cwirla S, Phillips JH. Comparative studies of human FcRIII-positive and negative natural killer cells. J Immunol. 1989;143(10):3183–91.
    • (1989) J Immunol , vol.143 , Issue.10 , pp. 3183-3191
    • Nagler, A.1    Lanier, L.L.2    Cwirla, S.3    Phillips, J.H.4
  • 59
    • 0037716818 scopus 로고    scopus 로고
    • Natural killer cell receptor signaling
    • PID: 12787756
    • Lanier LL. Natural killer cell receptor signaling. Curr Opin Immunol. 2003;15(3):308–14.
    • (2003) Curr Opin Immunol , vol.15 , Issue.3 , pp. 308-314
    • Lanier, L.L.1
  • 60
    • 9444249908 scopus 로고    scopus 로고
    • Natural killer cell signaling pathways
    • PID: 15567854
    • Vivier E, Nunes JA, Vely F. Natural killer cell signaling pathways. Science. 2004;306(5701):1517–9.
    • (2004) Science , vol.306 , Issue.5701 , pp. 1517-1519
    • Vivier, E.1    Nunes, J.A.2    Vely, F.3
  • 62
    • 33846467149 scopus 로고    scopus 로고
    • + NK cells downregulate CD16 following target cell induced activation of matrix metaloprteinases. Letter to the editor
    • + NK cells downregulate CD16 following target cell induced activation of matrix metaloprteinases. Letter to the editor. Leukemia. 2007;21(2):356–9.
    • (2007) Leukemia , vol.21 , Issue.2 , pp. 356-359
    • Gryzwacz, B.1    Kataria, N.2    Verneris, M.R.3
  • 63
    • 84879703012 scopus 로고    scopus 로고
    • NK cell CD16 surface expression and function is regulated by a disintegrin and metalloprotease-17 (ADAM17)
    • PID: 23487023
    • Romee R, Foley B, Lenvik T, Wang Y, Zhang B, Ankarlo D, Luo X, et al. NK cell CD16 surface expression and function is regulated by a disintegrin and metalloprotease-17 (ADAM17). Blood. 2013;121(18):3599–608.
    • (2013) Blood , vol.121 , Issue.18 , pp. 3599-3608
    • Romee, R.1    Foley, B.2    Lenvik, T.3    Wang, Y.4    Zhang, B.5    Ankarlo, D.6    Luo, X.7
  • 65
    • 80054094832 scopus 로고    scopus 로고
    • Clinical significance of the HLA-E and CD94/NKG2 interaction
    • Iwaszko M, Bogunia-Kubik K. Clinical significance of the HLA-E and CD94/NKG2 interaction. Arch Immunol Ther Exp (Warsz). 2011;59(5):353–67.
    • (2011) Arch Immunol Ther Exp (Warsz) , vol.59 , Issue.5 , pp. 353-367
    • Iwaszko, M.1    Bogunia-Kubik, K.2
  • 66
    • 0037011156 scopus 로고    scopus 로고
    • A signal peptide derived from hsp60 binds HLA-E and interferes with CD94/NKG2A recognition
    • PID: 12461076
    • Michaelsson J, Teixeira de Matos C, Achour A, Lanier LL, Karre K, Soderstrom K. A signal peptide derived from hsp60 binds HLA-E and interferes with CD94/NKG2A recognition. J Exp Med. 2002;196(11):1403–14.
    • (2002) J Exp Med , vol.196 , Issue.11 , pp. 1403-1414
    • Michaelsson, J.1    Teixeira de Matos, C.2    Achour, A.3    Lanier, L.L.4    Karre, K.5    Soderstrom, K.6
  • 67
    • 84862578622 scopus 로고    scopus 로고
    • HLA-E/β2 microglobulin overexpression in colorectal cancer is associated with recruitment of inhibitory immune cells and tumor progression
    • PID: 21953582
    • Bossard C, Bézieau S, Matysiak-Budnik T, Volteau C, Laboisse CL, Jotereau F, Mosnier JF. HLA-E/β2 microglobulin overexpression in colorectal cancer is associated with recruitment of inhibitory immune cells and tumor progression. Int J Cancer. 2012;131(4):855–63.
    • (2012) Int J Cancer , vol.131 , Issue.4 , pp. 855-863
    • Bossard, C.1    Bézieau, S.2    Matysiak-Budnik, T.3    Volteau, C.4    Laboisse, C.L.5    Jotereau, F.6    Mosnier, J.F.7
  • 68
    • 0032758440 scopus 로고    scopus 로고
    • Inhibitory and activating receptors involved in immune surveillance by human NK and myeloid cells
    • PID: 10577499
    • Colonna M, Nakajima H, Cella M. Inhibitory and activating receptors involved in immune surveillance by human NK and myeloid cells. J Leukoc Biol. 1999;66(5):718–22.
    • (1999) J Leukoc Biol , vol.66 , Issue.5 , pp. 718-722
    • Colonna, M.1    Nakajima, H.2    Cella, M.3
  • 70
    • 84905671445 scopus 로고    scopus 로고
    • Complexity and diversity of the NKR-P1: Clr (Klrb1:Clec2) recognition systems
    • PID: 24917862
    • Kirkham CL, Carlyle JR. Complexity and diversity of the NKR-P1: Clr (Klrb1:Clec2) recognition systems. Front Immunol. 2014;5:214.
    • (2014) Front Immunol , vol.5 , pp. 214
    • Kirkham, C.L.1    Carlyle, J.R.2
  • 71
    • 84860328949 scopus 로고    scopus 로고
    • Human NK cells at early stages of differentiation produce CXCL8 and express CD161 molecule that functions as an activating receptor
    • PID: 22403260
    • Montaldo E, Vitale C, Cottalasso F, Conte R, Glatzer T, Ambrosini P, Moretta L, Mingari MC. Human NK cells at early stages of differentiation produce CXCL8 and express CD161 molecule that functions as an activating receptor. Blood. 2012;119(17):3987–96.
    • (2012) Blood , vol.119 , Issue.17 , pp. 3987-3996
    • Montaldo, E.1    Vitale, C.2    Cottalasso, F.3    Conte, R.4    Glatzer, T.5    Ambrosini, P.6    Moretta, L.7    Mingari, M.C.8
  • 72
    • 0032193771 scopus 로고    scopus 로고
    • Differential transcriptional regulation of CD161 and a novel gene, 197/15a, by IL-2, IL-15, and IL-12 in NK and T cells
    • PID: 9759869
    • Azzoni L, Zatsepina O, Abebe B, Bennett IM, Kanakaraj P, Perussia B. Differential transcriptional regulation of CD161 and a novel gene, 197/15a, by IL-2, IL-15, and IL-12 in NK and T cells. J Immunol. 1998;161(7):3493–500.
    • (1998) J Immunol , vol.161 , Issue.7 , pp. 3493-3500
    • Azzoni, L.1    Zatsepina, O.2    Abebe, B.3    Bennett, I.M.4    Kanakaraj, P.5    Perussia, B.6
  • 73
    • 0027966063 scopus 로고
    • Human NKR-P1A. A disulfide-linked homodimer of the C-type lectin superfamily expressed by a subset of NK and T lymphocytes
    • PID: 8077657
    • Lanier LL, Chang C, Phillips JH. Human NKR-P1A. A disulfide-linked homodimer of the C-type lectin superfamily expressed by a subset of NK and T lymphocytes. J Immunol. 1994;153(6):2417–28.
    • (1994) J Immunol , vol.153 , Issue.6 , pp. 2417-2428
    • Lanier, L.L.1    Chang, C.2    Phillips, J.H.3
  • 75
    • 29144444611 scopus 로고    scopus 로고
    • Cutting edge: lectin-like transcript-1 is a ligand for the inhibitory human NKR-P1A receptor
    • PID: 16339513
    • Rosen DB, Bettadapura J, Alsharifi M, Mathew PA, Warren HS, Lanier LL. Cutting edge: lectin-like transcript-1 is a ligand for the inhibitory human NKR-P1A receptor. J Immunol. 2005;175(12):7796–9.
    • (2005) J Immunol , vol.175 , Issue.12 , pp. 7796-7799
    • Rosen, D.B.1    Bettadapura, J.2    Alsharifi, M.3    Mathew, P.A.4    Warren, H.S.5    Lanier, L.L.6
  • 76
    • 0031046520 scopus 로고    scopus 로고
    • Divergent functions of lectin-like receptors on NK cells
    • PID: 9059884
    • Ryan JC, Seaman WE. Divergent functions of lectin-like receptors on NK cells. Immunol Rev. 1997;155:79–89.
    • (1997) Immunol Rev , vol.155 , pp. 79-89
    • Ryan, J.C.1    Seaman, W.E.2
  • 77
    • 84877602763 scopus 로고    scopus 로고
    • NK cell-based immunotherapy for malignant diseases
    • PID: 23604045
    • Cheng M, Chen Y, Xiao W, Sun R, Tian Z. NK cell-based immunotherapy for malignant diseases. Cell Mol Immunol. 2013;10(3):230–52.
    • (2013) Cell Mol Immunol , vol.10 , Issue.3 , pp. 230-252
    • Cheng, M.1    Chen, Y.2    Xiao, W.3    Sun, R.4    Tian, Z.5
  • 79
    • 0036716947 scopus 로고    scopus 로고
    • NK cells: a lesson from mismatched hematopoietic transplantation
    • PID: 12200065
    • Velardi A, Ruggeri L, Moretta A, Moretta L. NK cells: a lesson from mismatched hematopoietic transplantation. Trends Immunol. 2002;23(9):438–44.
    • (2002) Trends Immunol , vol.23 , Issue.9 , pp. 438-444
    • Velardi, A.1    Ruggeri, L.2    Moretta, A.3    Moretta, L.4
  • 80
    • 0037086131 scopus 로고    scopus 로고
    • Effectiveness of donor natural killer cell alloreactivity in mismatched hematopoietic transplants
    • PID: 11896281
    • Ruggeri L, Capanni M, Urbani E, Perruccio K, Shlomchik WD, Tosti A, Posati S, et al. Effectiveness of donor natural killer cell alloreactivity in mismatched hematopoietic transplants. Science. 2002;295(5562):2097–100.
    • (2002) Science , vol.295 , Issue.5562 , pp. 2097-2100
    • Ruggeri, L.1    Capanni, M.2    Urbani, E.3    Perruccio, K.4    Shlomchik, W.D.5    Tosti, A.6    Posati, S.7
  • 81
    • 0033168770 scopus 로고    scopus 로고
    • Role of natural killer cell alloreactivity in HLA-mismatched hematopoietic stem cell transplantation
    • PID: 10381530
    • Ruggeri L, Capanni M, Casucci M, Volpi I, Tosti A, Perruccio K, Urbani E, et al. Role of natural killer cell alloreactivity in HLA-mismatched hematopoietic stem cell transplantation. Blood. 1999;94(1):333–9.
    • (1999) Blood , vol.94 , Issue.1 , pp. 333-339
    • Ruggeri, L.1    Capanni, M.2    Casucci, M.3    Volpi, I.4    Tosti, A.5    Perruccio, K.6    Urbani, E.7
  • 82
    • 34247581578 scopus 로고    scopus 로고
    • Missing KIR ligands are associated with less relapse and increased graft-versus-host disease (GVHD) following unrelated donor allogeneic HCT
    • PID: 17317850
    • Miller JS, Cooley S, Parham P, Farag SS, Verneris MR, McQueen KL, Guethlein LA, et al. Missing KIR ligands are associated with less relapse and increased graft-versus-host disease (GVHD) following unrelated donor allogeneic HCT. Blood. 2007;109(11):5058–61.
    • (2007) Blood , vol.109 , Issue.11 , pp. 5058-5061
    • Miller, J.S.1    Cooley, S.2    Parham, P.3    Farag, S.S.4    Verneris, M.R.5    McQueen, K.L.6    Guethlein, L.A.7
  • 84
    • 34247268450 scopus 로고    scopus 로고
    • Donor-recipient combinations of group A and B KIR haplotypes and HLA class I ligand affect the outcome of HLA-matched, sibling donor hematopoietic cell transplantation
    • PID: 17462498
    • McQueen KL, Dorighi KM, Guethlein LA, Wong R, Sanjanwala B, Parham P. Donor-recipient combinations of group A and B KIR haplotypes and HLA class I ligand affect the outcome of HLA-matched, sibling donor hematopoietic cell transplantation. Hum Immunol. 2007;68(5):309–23.
    • (2007) Hum Immunol , vol.68 , Issue.5 , pp. 309-323
    • McQueen, K.L.1    Dorighi, K.M.2    Guethlein, L.A.3    Wong, R.4    Sanjanwala, B.5    Parham, P.6
  • 86
    • 84991543926 scopus 로고    scopus 로고
    • Killer immunoglobulin-like receptors and tumor immunity
    • PID: 24592397
    • Benson DM Jr, Caligiuri MA. Killer immunoglobulin-like receptors and tumor immunity. Cancer Immunol Res. 2014;2(2):99–104.
    • (2014) Cancer Immunol Res , vol.2 , Issue.2 , pp. 99-104
    • Benson, D.M.1    Caligiuri, M.A.2
  • 87
    • 51649084785 scopus 로고    scopus 로고
    • Combination therapy using IL-2 and anti-CD25 results in augmented natural killer cell-mediated antitumor responses
    • PID: 18804038
    • Hallett WH, Ames E, Alvarez M, Barao I, Taylor PA, Blazar BR, Murphy WJ. Combination therapy using IL-2 and anti-CD25 results in augmented natural killer cell-mediated antitumor responses. Biol Blood Marrow Transplant. 2008;14(10):1088–99.
    • (2008) Biol Blood Marrow Transplant , vol.14 , Issue.10 , pp. 1088-1099
    • Hallett, W.H.1    Ames, E.2    Alvarez, M.3    Barao, I.4    Taylor, P.A.5    Blazar, B.R.6    Murphy, W.J.7
  • 88
    • 84891865149 scopus 로고    scopus 로고
    • Advantages and clinical applications of natural killer cells in cancer immunotherapy
    • PID: 23989217
    • Ames E, Murphy WJ. Advantages and clinical applications of natural killer cells in cancer immunotherapy. Cancer Immunol Immunother. 2014;63(1):21–8.
    • (2014) Cancer Immunol Immunother , vol.63 , Issue.1 , pp. 21-28
    • Ames, E.1    Murphy, W.J.2
  • 89
    • 78649880476 scopus 로고    scopus 로고
    • Novel aspects of in vitro IL-2 or IFN-α enhanced NK cytotoxicity of healthy individuals based on NKG2D and CD161 NK cell receptor induction
    • PID: 20800424
    • Konjević G, Mirjačić Martinović K, Vuletić A, Radenković S. Novel aspects of in vitro IL-2 or IFN-α enhanced NK cytotoxicity of healthy individuals based on NKG2D and CD161 NK cell receptor induction. Biomed Pharmacother. 2010;64(10):663–71.
    • (2010) Biomed Pharmacother , vol.64 , Issue.10 , pp. 663-671
    • Konjević, G.1    Mirjačić Martinović, K.2    Vuletić, A.3    Radenković, S.4
  • 90
    • 78149479990 scopus 로고    scopus 로고
    • Cytokine regulation of natural killer cell effector functions
    • PID: 20623510
    • Zwirner NW, Domaica CI. Cytokine regulation of natural killer cell effector functions. BioFactors. 2010;36(4):274–88.
    • (2010) BioFactors , vol.36 , Issue.4 , pp. 274-288
    • Zwirner, N.W.1    Domaica, C.I.2
  • 91
    • 84920264251 scopus 로고    scopus 로고
    • In-vitro activation of natural killer cells from regional lymph nodes of melanoma patients with interleukin-2 and interleukin-15
    • PID: 25380182
    • Vuletić AM, Jovanić IP, Jurišić VB, Milovanović ZM, Nikolić SS, Tanić NT, Konjević GM. In-vitro activation of natural killer cells from regional lymph nodes of melanoma patients with interleukin-2 and interleukin-15. Melanoma Res. 2015;25(1):22–34.
    • (2015) Melanoma Res , vol.25 , Issue.1 , pp. 22-34
    • Vuletić, A.M.1    Jovanić, I.P.2    Jurišić, V.B.3    Milovanović, Z.M.4    Nikolić, S.S.5    Tanić, N.T.6    Konjević, G.M.7
  • 92
    • 80052953360 scopus 로고    scopus 로고
    • Complex regulation of human NKG2D-DAP10 cell surface expression: opposing roles of the γc cytokines and TGF-β1
    • PID: 21816829
    • Park YP, Choi SC, Kiesler P, Gil-Krzewska A, Borrego F, Weck J, Krzewski K, Coligan JE. Complex regulation of human NKG2D-DAP10 cell surface expression: opposing roles of the γc cytokines and TGF-β1. Blood. 2011;118(11):3019–27.
    • (2011) Blood , vol.118 , Issue.11 , pp. 3019-3027
    • Park, Y.P.1    Choi, S.C.2    Kiesler, P.3    Gil-Krzewska, A.4    Borrego, F.5    Weck, J.6    Krzewski, K.7    Coligan, J.E.8
  • 93
    • 0034911823 scopus 로고    scopus 로고
    • Therapeutic implications of the kinetics of immunomodulation during single or combined treatment of melanoma patients with dacarbazine and interferon-alpha
    • PID: 11583285
    • Konjević G, Jović V, Radulović S, Jelić S, Dzodić R, Spuzić I. Therapeutic implications of the kinetics of immunomodulation during single or combined treatment of melanoma patients with dacarbazine and interferon-alpha. Neoplasma. 2001;48(3):175–81.
    • (2001) Neoplasma , vol.48 , Issue.3 , pp. 175-181
    • Konjević, G.1    Jović, V.2    Radulović, S.3    Jelić, S.4    Dzodić, R.5    Spuzić, I.6
  • 95
    • 84872225254 scopus 로고    scopus 로고
    • Sustained effector function of IL-12/15/18-preactivated NK cells against established tumors
    • PID: 23209317
    • Ni J, Miller M, Stojanovic A, Garbi N, Cerwenka A. Sustained effector function of IL-12/15/18-preactivated NK cells against established tumors. J Exp Med. 2012;209(13):2351–65.
    • (2012) J Exp Med , vol.209 , Issue.13 , pp. 2351-2365
    • Ni, J.1    Miller, M.2    Stojanovic, A.3    Garbi, N.4    Cerwenka, A.5
  • 96
    • 84895832116 scopus 로고    scopus 로고
    • Preactivation with IL-12, IL-15, and IL-18 induces CD25 and a functional high-affinity IL-2 receptor on human cytokine-induced memory-like natural killer cells
    • PID: 24434782
    • Leong JW, Chase JM, Romee R, Schneider SE, Sullivan RP, Cooper MA, Fehniger TA. Preactivation with IL-12, IL-15, and IL-18 induces CD25 and a functional high-affinity IL-2 receptor on human cytokine-induced memory-like natural killer cells. Biol Blood Marrow Transplant. 2014;20(4):463–73.
    • (2014) Biol Blood Marrow Transplant , vol.20 , Issue.4 , pp. 463-473
    • Leong, J.W.1    Chase, J.M.2    Romee, R.3    Schneider, S.E.4    Sullivan, R.P.5    Cooper, M.A.6    Fehniger, T.A.7
  • 97
    • 0027243263 scopus 로고
    • Stage dependence of NK cell activity and its modulation by interleukin 2 in patients with breast cancer
    • PID: 8350959
    • Konjević G, Spuzić I. Stage dependence of NK cell activity and its modulation by interleukin 2 in patients with breast cancer. Neoplasma. 1993;40(2):81–5.
    • (1993) Neoplasma , vol.40 , Issue.2 , pp. 81-85
    • Konjević, G.1    Spuzić, I.2
  • 98
    • 78349306897 scopus 로고    scopus 로고
    • In-vitro IL-2 or IFN-α-induced NKG2D and CD161 NK cell receptor expression indicates novel aspects of NK cell activation in metastatic melanoma patients
    • PID: 20938360
    • Konjević G, Mirjačić Martinović K, Vuletić A, Babović N. In-vitro IL-2 or IFN-α-induced NKG2D and CD161 NK cell receptor expression indicates novel aspects of NK cell activation in metastatic melanoma patients. Melanoma Res. 2010;20(6):459–67.
    • (2010) Melanoma Res , vol.20 , Issue.6 , pp. 459-467
    • Konjević, G.1    Mirjačić Martinović, K.2    Vuletić, A.3    Babović, N.4
  • 99
    • 84928787890 scopus 로고    scopus 로고
    • Favorable in vitro effects of combined IL-12 and IL-18 treatment on NK cell cytotoxicity and CD25 receptor expression in metastatic melanoma patients
    • PID: 25889680
    • Mirjačić Martinović K, Babović N, Džodić R, Jurišić V, Matković S, Konjević G. Favorable in vitro effects of combined IL-12 and IL-18 treatment on NK cell cytotoxicity and CD25 receptor expression in metastatic melanoma patients. J Transl Med. 2015;13:120.
    • (2015) J Transl Med , vol.13 , pp. 120
    • Mirjačić Martinović, K.1    Babović, N.2    Džodić, R.3    Jurišić, V.4    Matković, S.5    Konjević, G.6
  • 100
    • 84897566294 scopus 로고    scopus 로고
    • Phase I study of GC1008 (fresolimumab): a human anti-transforming growth factor-beta (TGFβ) monoclonal antibody in patients with advanced malignant melanoma or renal cell carcinoma
    • PID: 24618589
    • Morris JC, Tan AR, Olencki TE, Shapiro GI, Dezube BJ, Reiss M, Hsu FJ, et al. Phase I study of GC1008 (fresolimumab): a human anti-transforming growth factor-beta (TGFβ) monoclonal antibody in patients with advanced malignant melanoma or renal cell carcinoma. PLoS ONE. 2014;9:e90353.
    • (2014) PLoS ONE , vol.9 , pp. e90353
    • Morris, J.C.1    Tan, A.R.2    Olencki, T.E.3    Shapiro, G.I.4    Dezube, B.J.5    Reiss, M.6    Hsu, F.J.7
  • 103
    • 84892156997 scopus 로고    scopus 로고
    • Combination immune therapies to enhance anti-tumor responses by NK cells
    • PID: 24391651
    • Mentlik James A, Cohen AD, Campbell KS. Combination immune therapies to enhance anti-tumor responses by NK cells. Front Immunol. 2013;4:481.
    • (2013) Front Immunol , vol.4 , pp. 481
    • Mentlik James, A.1    Cohen, A.D.2    Campbell, K.S.3
  • 104
    • 77950613332 scopus 로고    scopus 로고
    • Sorafenib inhibits the shedding of major histocompatibility complex class I-related chain A on hepatocellular carcinoma cells by down-regulating a disintegrin and metalloproteinase 9
    • PID: 20099300
    • Kohga K, Takehara T, Tatsumi T, Ishida H, Miyagi T, Hosui A, Hayashi N. Sorafenib inhibits the shedding of major histocompatibility complex class I-related chain A on hepatocellular carcinoma cells by down-regulating a disintegrin and metalloproteinase 9. Hepatology. 2010;51(4):1264–73.
    • (2010) Hepatology , vol.51 , Issue.4 , pp. 1264-1273
    • Kohga, K.1    Takehara, T.2    Tatsumi, T.3    Ishida, H.4    Miyagi, T.5    Hosui, A.6    Hayashi, N.7
  • 105
    • 84886443514 scopus 로고    scopus 로고
    • CTLA-4 and PD-1/PD-L1 blockade: new immunotherapeutic modalities with durable clinical benefit in melanoma patients
    • PID: 24089443
    • Ott PA, Hodi FS, Robert C. CTLA-4 and PD-1/PD-L1 blockade: new immunotherapeutic modalities with durable clinical benefit in melanoma patients. Clin Cancer Res. 2013;19(19):5300–9.
    • (2013) Clin Cancer Res , vol.19 , Issue.19 , pp. 5300-5309
    • Ott, P.A.1    Hodi, F.S.2    Robert, C.3
  • 106
    • 77957701558 scopus 로고    scopus 로고
    • The PD-1/PD-L1 axis modulates the natural killer cell versus multiple myeloma effect: a therapeutic target for CT-011, a novel monoclonal anti-PD-1 antibody
    • PID: 20460501
    • Benson DM Jr, Bakan CE, Mishra A, Hofmeister CC, Efebera Y, Becknell B, Baiocchi RA, et al. The PD-1/PD-L1 axis modulates the natural killer cell versus multiple myeloma effect: a therapeutic target for CT-011, a novel monoclonal anti-PD-1 antibody. Blood. 2010;116(13):2286–94.
    • (2010) Blood , vol.116 , Issue.13 , pp. 2286-2294
    • Benson, D.M.1    Bakan, C.E.2    Mishra, A.3    Hofmeister, C.C.4    Efebera, Y.5    Becknell, B.6    Baiocchi, R.A.7
  • 107
    • 84897502067 scopus 로고    scopus 로고
    • NKG2D CARs as cell therapy for cancer
    • PID: 24667963
    • Sentman CL, Meehan KR. NKG2D CARs as cell therapy for cancer. Cancer J. 2014;20:156–9.
    • (2014) Cancer J , vol.20 , pp. 156-159
    • Sentman, C.L.1    Meehan, K.R.2
  • 108
    • 84883208183 scopus 로고    scopus 로고
    • Natural killer cell mediated antibody-dependent cellular cytotoxicity in tumor immunotherapy with therapeutic antibodies
    • PID: 23543707
    • Seidel UJ, Schlegel P, Lang P. Natural killer cell mediated antibody-dependent cellular cytotoxicity in tumor immunotherapy with therapeutic antibodies. Front Immunol. 2013;4:76.
    • (2013) Front Immunol , vol.4 , pp. 76
    • Seidel, U.J.1    Schlegel, P.2    Lang, P.3
  • 109
    • 84883244752 scopus 로고    scopus 로고
    • Natural killer cell biology: an update and future directions
    • PID: 23906377
    • Campbell KS, Hasegawa J. Natural killer cell biology: an update and future directions. J Allergy Clin Immunol. 2013;132(3):536–44.
    • (2013) J Allergy Clin Immunol , vol.132 , Issue.3 , pp. 536-544
    • Campbell, K.S.1    Hasegawa, J.2
  • 110
    • 30144443832 scopus 로고    scopus 로고
    • Synergy among receptors on resting NK cells for the activation of natural cytotoxicity and cytokine secretion
    • PID: 16150947
    • Bryceson YT, March ME, Ljunggren HG, Long EO. Synergy among receptors on resting NK cells for the activation of natural cytotoxicity and cytokine secretion. Blood. 2006;107(1):159–66.
    • (2006) Blood , vol.107 , Issue.1 , pp. 159-166
    • Bryceson, Y.T.1    March, M.E.2    Ljunggren, H.G.3    Long, E.O.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.