-
1
-
-
84866034901
-
Targeting tumor perfusion and oxygenation to improve the outcome of anticancer therapy
-
Jordan, B. F., Sonveaux, P. Targeting tumor perfusion and oxygenation to improve the outcome of anticancer therapy. Front. Pharmacol., 2012, 3, 94.
-
(2012)
Front. Pharmacol.
, vol.3
, pp. 94
-
-
Jordan, B.F.1
Sonveaux, P.2
-
2
-
-
84898542253
-
Hypoxia in tumors: Pathogenesis-related classification, characterization of hypoxia subtypes, and associated biological and clinical implications
-
Vaupel, P.; Mayer, A. Hypoxia in tumors: pathogenesis-related classification, characterization of hypoxia subtypes, and associated biological and clinical implications. Adv. Exp. Med. Biol., 2014, 812, 19-24.
-
(2014)
Adv. Exp. Med. Biol.
, vol.812
, pp. 19-24
-
-
Vaupel, P.1
Mayer, A.2
-
3
-
-
84904035287
-
Hy-poxia signaling and the metastatic phenotype
-
Mujcic, H.; Hill, R.P.; Koritzinsky, M.; Wouters, B.G. Hy-poxia signaling and the metastatic phenotype. Curr. Mol. Med., 2014, 14(5), 565-579.
-
(2014)
Curr. Mol. Med.
, vol.14
, Issue.5
, pp. 565-579
-
-
Mujcic, H.1
Hill, R.P.2
Koritzinsky, M.3
Wouters, B.G.4
-
5
-
-
84922393506
-
Melittin enhances radiosensitivity of hypoxic head and neck squamous cell carcinoma by suppressing HIF-1alpha
-
Yang, X.;, Zhu, H.; Ge, Y.; Liu, J.; Cai, J.; Qin, Q.; Zhan, L.; Zhang, C.; Xu, L.; Liu, Z.; Yang, Y.; Yang, Y.; Ma, J.; Cheng, H.; Sun, X. Melittin enhances radiosensitivity of hypoxic head and neck squamous cell carcinoma by suppressing HIF-1alpha. Tumour Biol., 2014, 35(10), 10443-10448.
-
(2014)
Tumour Biol.
, vol.35
, Issue.10
, pp. 10443-10448
-
-
Yang, X.1
Zhu, H.2
Ge, Y.3
Liu, J.4
Cai, J.5
Qin, Q.6
Zhan, L.7
Zhang, C.8
Xu, L.9
Liu, Z.10
Yang, Y.11
Yang, Y.12
Ma, J.13
Cheng, H.14
Sun, X.15
-
6
-
-
0035812789
-
Expression and characterization of hypoxia-inducible factor (HIF)-3alpha in human kidney: Suppression of HIF-mediated gene expression by HIF-3alpha
-
Hara, S.; Hamada, J.; Kobayashi, C.; Kondo, Y.; Imura, N. Expression and characterization of hypoxia-inducible factor (HIF)-3alpha in human kidney: suppression of HIF-mediated gene expression by HIF-3alpha. Biochem. Bio-phys. Res. Commun., 2001, 287(4), 808-813.
-
(2001)
Biochem. Bio-phys. Res. Commun.
, vol.287
, Issue.4
, pp. 808-813
-
-
Hara, S.1
Hamada, J.2
Kobayashi, C.3
Kondo, Y.4
Imura, N.5
-
7
-
-
84897708817
-
Hypoxia and cancer cell metabolism
-
Huang, D.; Li, C.;. Zhang, H. Hypoxia and cancer cell metabolism. Acta Biochim. Biophys. Sin. (Shanghai), 2014, 46(3), 214-219.
-
(2014)
Acta Biochim. Biophys. Sin. (Shanghai)
, vol.46
, Issue.3
, pp. 214-219
-
-
Huang, D.1
Li, C.2
Zhang, H.3
-
8
-
-
84934437860
-
Hypoxia and regulation of cancer cell stemness
-
Yun, Z.;Lin, Q. Hypoxia and regulation of cancer cell stemness. Adv. Exp. Med. Biol., 2014, 772, 41-53.
-
(2014)
Adv. Exp. Med. Biol.
, vol.772
, pp. 41-53
-
-
Yun, Z.1
Lin, Q.2
-
9
-
-
84906081436
-
HIF-1 signaling in drug resistance to chemotherapy
-
Warfel, N. A., El-Deiry, W. S. HIF-1 signaling in drug resistance to chemotherapy. Curr. Med. Chem., 2014, 21(26), 3021-3028.
-
(2014)
Curr. Med. Chem.
, vol.21
, Issue.26
, pp. 3021-3028
-
-
Warfel, N.A.1
El-Deiry, W.S.2
-
10
-
-
84899095093
-
HIF-1alpha P582S and A588T polymorphisms and digestive system cancer risk-A meta-analysis
-
Yang, X.; Zhang, C.; Zhu, H. C.; Qin, Q.;Zhao, L. J.; Liu, J.; Xu, L. P.; Zhang, Q.; Cai, J.; Ma, J. X.; Cheng, H. Y.; Sun, X. C. HIF-1alpha P582S and A588T polymorphisms and digestive system cancer risk-a meta-analysis. Tumour Biol., 2014, 35(3), 2825-2830.
-
(2014)
Tumour Biol.
, vol.35
, Issue.3
, pp. 2825-2830
-
-
Yang, X.1
Zhang, C.2
Zhu, H.C.3
Qin, Q.4
Zhao, L.J.5
Liu, J.6
Xu, L.P.7
Zhang, Q.8
Cai, J.9
Ma, J.X.10
Cheng, H.Y.11
Sun, X.C.12
-
11
-
-
84894147580
-
HIF-1alpha 1772 C/T and 1790 G/A polymorphisms are significantly associated with higher cancer risk: An updated meta-analysis from 34 case-control studies
-
Yang, X.; Zhu, H. C; Zhang, C.; Qin, Q.; Liu, J.; Xu, L. P.; Zhao, L. J.;Zhang, Q.; Cai, J.; Ma, X.; Cheng, H. Y.; Sun, X. C. HIF-1alpha 1772 C/T and 1790 G/A polymorphisms are significantly associated with higher cancer risk: an updated meta-analysis from 34 case-control studies. PLoS One, 2013, 8(11), e80396.
-
(2013)
PLoS One
, vol.8
, Issue.11
, pp. e80396
-
-
Yang, X.1
Zhu, H.C.2
Zhang, C.3
Qin, Q.4
Liu, J.5
Xu, L.P.6
Zhao, L.J.7
Zhang, Q.8
Cai, J.9
Ma, X.10
Cheng, H.Y.11
Sun, X.C.12
-
12
-
-
84902187969
-
Exosome in tumour microenvironment: Overview of the crosstalk between normal and cancer cells
-
Roma-Rodrigues, C.; Fernandes, A. R.; Baptista, P. V. Exosome in tumour microenvironment: overview of the crosstalk between normal and cancer cells. Biomed. Res. Int., 2014, 2014, 179486.
-
(2014)
Biomed. Res. Int.
, vol.2014
, pp. 179486
-
-
Roma-Rodrigues, C.1
Fernandes, A.R.2
Baptista, P.V.3
-
13
-
-
84874980515
-
Exosomes for targeted siRNA delivery across biological barriers
-
EL Andaloussi, S.; Lakhal, S.; Mager, I.; Wood, M. J. A. Exosomes for targeted siRNA delivery across biological barriers. Adv. Drug Deliv. Rev., 2013, 65(3), 391-397.
-
(2013)
Adv. Drug Deliv. Rev.
, vol.65
, Issue.3
, pp. 391-397
-
-
Andaloussi S, E.L.1
Lakhal, S.2
Mager, I.3
Wood, M.J.A.4
-
14
-
-
84904607973
-
Functions and therapeutic roles of exosomes in cancer
-
Tickner, J. A.; Urquhart, A. J.; Stephenson, S. A.; Richard, D. J.; O'Byrne, K. J. Functions and therapeutic roles of exosomes in cancer. Front. Oncol., 2014, 4, 127.
-
(2014)
Front. Oncol.
, vol.4
, pp. 127
-
-
Tickner, J.A.1
Urquhart, A.J.2
Stephenson, S.A.3
Richard, D.J.4
O'Byrne, K.J.5
-
15
-
-
84890313522
-
Exosomes in cancer development, metastasis, and drug resistance: A comprehensive review."
-
Azmi, A.S.; Bao, B.; Sarkar, F.H. "Exosomes in cancer development, metastasis, and drug resistance: a comprehensive review." Cancer Metastasis Rev., 2013, 32(3-4): 623-642.
-
(2013)
Cancer Metastasis Rev.
, vol.32
, Issue.3-4
, pp. 623-642
-
-
Azmi, A.S.1
Bao, B.2
Sarkar, F.H.3
-
16
-
-
84901315268
-
Tumor-derived exosomes: A message delivery system for tumor progression
-
Atay, S.; Godwin, A. K. Tumor-derived exosomes: A message delivery system for tumor progression. Commun. In-tegr. Biol., 2014, 7(1), e28231.
-
(2014)
Commun. In-tegr. Biol.
, vol.7
, Issue.1
, pp. e28231
-
-
Atay, S.1
Godwin, A.K.2
-
17
-
-
33646812544
-
Circulating endothelial microparticles in acute ischemic stroke: A link to severity, lesion volume and outcome
-
Simak, J.; Gelderman, M.P.; Yu, H.; Wright, V.; Baird, A.E. Circulating endothelial microparticles in acute ischemic stroke: a link to severity, lesion volume and outcome. J. Thromb. Haemost., 2006, 4(6), 1296-1302.
-
(2006)
J. Thromb. Haemost.
, vol.4
, Issue.6
, pp. 1296-1302
-
-
Simak, J.1
Gelderman, M.P.2
Yu, H.3
Wright, V.4
Baird, A.E.5
-
18
-
-
77953142134
-
Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and me-tastatic potential by secretion of proteins and exosomes
-
Park, J.E.; Tan, H.S.; Datta, A.; Lai, R.C.; Zhang, H.; Meng, W.; Lim, S.K.; Sze, S.K. Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and me-tastatic potential by secretion of proteins and exosomes. Mol. Cell Proteomics, 2010, 9(6), 1085-1099.
-
(2010)
Mol. Cell Proteomics
, vol.9
, Issue.6
, pp. 1085-1099
-
-
Park, J.E.1
Tan, H.S.2
Datta, A.3
Lai, R.C.4
Zhang, H.5
Meng, W.6
Lim, S.K.7
Sze, S.K.8
-
19
-
-
84873128605
-
Microvesiculation and disease
-
Inal, J. M.; Fairbrother, U.; Heugh, S. Microvesiculation and disease. Biochem. Soc. Trans., 2013, 41(1), 237-240.
-
(2013)
Biochem. Soc. Trans.
, vol.41
, Issue.1
, pp. 237-240
-
-
Inal, J.M.1
Fairbrother, U.2
Heugh, S.3
-
20
-
-
84902968221
-
The cancer stem cell niche: Cross talk between cancer stem cells and their mi-croenvironment
-
Ye, J.; Wu, D.; Wu, P.; Chen, Z.; Huang, J. The cancer stem cell niche: cross talk between cancer stem cells and their mi-croenvironment. Tumour Biol., 2014, 35(5), 3945-3951.
-
(2014)
Tumour Biol.
, vol.35
, Issue.5
, pp. 3945-3951
-
-
Ye, J.1
Wu, D.2
Wu, P.3
Chen, Z.4
Huang, J.5
-
21
-
-
84866502787
-
Hypoxic enhancement of exosome release by breast cancer cells
-
King, H.W.; Michael, M.Z.; Gleadle, J.M. Hypoxic enhancement of exosome release by breast cancer cells. BMC Cancer, 2012, 12, 421.
-
(2012)
BMC Cancer
, vol.12
, pp. 421
-
-
King, H.W.1
Michael, M.Z.2
Gleadle, J.M.3
-
22
-
-
84888986034
-
Exosomes derived from hypoxic leukemia cells enhance tube formation in endothelial cells
-
Tadokoro, H.; Umezu, T.; Ohyashiki, K.; Hirano T.; Ohya-shiki, J.H. Exosomes derived from hypoxic leukemia cells enhance tube formation in endothelial cells. J. Biol. Chem., 2013, 288(48): 34343-34351.
-
(2013)
J. Biol. Chem.
, vol.288
, Issue.48
, pp. 34343-34351
-
-
Tadokoro, H.1
Umezu, T.2
Ohyashiki, K.3
Hirano, T.4
Ohya-Shiki, J.H.5
-
23
-
-
84904876378
-
PPAR-γ and RXR ligands disrupt the inflammatory cross-talk in the hypoxic breast cancer stem cells niche
-
Papi, A.; De Carolis, S.; Bertoni, S.; Storci, G.; Sceberras, V.; Santini, D.; Ceccarelli, C.; Taffurelli, M.; Orlandi M.; Bonafe, M. PPAR-γ and RXR ligands disrupt the inflammatory cross-talk in the hypoxic breast cancer stem cells niche. J. Cell Physiol., 2014, 229(11), 1595-1606.
-
(2014)
J. Cell Physiol.
, vol.229
, Issue.11
, pp. 1595-1606
-
-
Papi, A.1
De Carolis, S.2
Bertoni, S.3
Storci, G.4
Sceberras, V.5
Santini, D.6
Ceccarelli, C.7
Taffurelli, M.8
Orlandi, M.9
Bonafe, M.10
-
24
-
-
84919680938
-
Exosomal miR-135b shed from hypoxic multiple myeloma cells enhances angiogene-sis by targeting factor-inhibiting HIF-1
-
Umezu, T.; Tadokoro, H.; Azuma, K.; Yoshizawa, S.; Ohyashiki, K.; Ohyashiki, J. H. Exosomal miR-135b shed from hypoxic multiple myeloma cells enhances angiogene-sis by targeting factor-inhibiting HIF-1. Blood, 2014, 124(25), 3748-3757.
-
(2014)
Blood
, vol.124
, Issue.25
, pp. 3748-3757
-
-
Umezu, T.1
Tadokoro, H.2
Azuma, K.3
Yoshizawa, S.4
Ohyashiki, K.5
Ohyashiki, J.H.6
-
25
-
-
84876927914
-
Exosomes reflect the hypoxic status of glioma cells and mediate hy-poxia-dependent activation of vascular cells during tumor development
-
Kucharzewska, P.; Christianson, H.C.; Welch, J.E.; Svensson, K.J.; Fredlund, E.; Ringnér, M.; Mörgelin, M.; Bourseau-Guilmain, E.; Bengzon, J.; Belting, M. Exosomes reflect the hypoxic status of glioma cells and mediate hy-poxia-dependent activation of vascular cells during tumor development. Proc. Natl. Acad. Sci. USA, 2013, 110(18), 7312-7317.
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, Issue.18
, pp. 7312-7317
-
-
Kucharzewska, P.1
Christianson, H.C.2
Welch, J.E.3
Svensson, K.J.4
Fredlund, E.5
Ringnér, M.6
Mörgelin, M.7
Bourseau-Guilmain, E.8
Bengzon, J.9
Belting, M.10
-
26
-
-
20244390010
-
Cleavage of L1 in exosomes and apoptotic membrane vesicles released from ovarian carcinoma cells
-
Gutwein, P.; Stoeck, A.; Riedle, S.; Gast, D.; Runz, S.; Condon, T. P.; Marme, A.; Phong, M. C.; Linderkamp, O.; Skorokhod, A.; Altevogt, P. Cleavage of L1 in exosomes and apoptotic membrane vesicles released from ovarian carcinoma cells. Clin. Cancer Res., 2005, 11(7), 2492-2501.
-
(2005)
Clin. Cancer Res.
, vol.11
, Issue.7
, pp. 2492-2501
-
-
Gutwein, P.1
Stoeck, A.2
Riedle, S.3
Gast, D.4
Runz, S.5
Condon, T.P.6
Marme, A.7
Phong, M.C.8
Linderkamp, O.9
Skorokhod, A.10
Altevogt, P.11
-
27
-
-
80051971645
-
Hypoxia triggers a proangiogenic pathway involving cancer cell microvesicles and PAR-2-mediated heparin-binding EGF signaling in en-dothelial cells
-
Svensson, K. J.; Kucharzewska, P.; Christianson, H. C.; Skold, S.; Lofstedt, T.; Johansson, M. C.; Morgelin, M.; Bengzon, J.; Ruf, W.; Belting, M. Hypoxia triggers a proangiogenic pathway involving cancer cell microvesicles and PAR-2-mediated heparin-binding EGF signaling in en-dothelial cells. Proc. Natl. Acad. Sci. USA, 2011, 108(32), 13147-13152.
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, Issue.32
, pp. 13147-13152
-
-
Svensson, K.J.1
Kucharzewska, P.2
Christianson, H.C.3
Skold, S.4
Lofstedt, T.5
Johansson, M.C.6
Morgelin, M.7
Bengzon, J.8
Ruf, W.9
Belting, M.10
-
28
-
-
84930763705
-
Exosomes secreted under hypoxia enhance in-vasiveness and stemness of prostate cancer cells by targeting adherens junction molecules
-
Ramteke, A.; Ting, H.; Agarwal, C.; Mateen, S.; Somasa-gara, R.; Hussain, A.; Graner, M.; Frederick, B.; Agarwal, R.; Deep, G. Exosomes secreted under hypoxia enhance in-vasiveness and stemness of prostate cancer cells by targeting adherens junction molecules. Mol. Carcinog., 2015, 54(7), 554-565.
-
(2015)
Mol. Carcinog.
, vol.54
, Issue.7
, pp. 554-565
-
-
Ramteke, A.1
Ting, H.2
Agarwal, C.3
Mateen, S.4
Somasa-Gara, R.5
Hussain, A.6
Graner, M.7
Frederick, B.8
Agarwal, R.9
Deep, G.10
-
29
-
-
84896408214
-
Exosomal HIF1alpha supports invasive potential of naso-pharyngeal carcinoma-associated LMP1-positive exosomes
-
Aga, M.; Bentz, G. L.; Raffa, S.; Torrisi, M. R.; Kondo, S.; Wakisaka, N.; Yoshizaki, T; Pagano, J.S.; Shackelford, J. Exosomal HIF1alpha supports invasive potential of naso-pharyngeal carcinoma-associated LMP1-positive exosomes. Oncogene, 2014, 33(37), 4613-4622.
-
(2014)
Oncogene
, vol.33
, Issue.37
, pp. 4613-4622
-
-
Aga, M.1
Bentz, G.L.2
Raffa, S.3
Torrisi, M.R.4
Kondo, S.5
Wakisaka, N.6
Yoshizaki, T.7
Pagano, J.S.8
Shackelford, J.9
-
30
-
-
84905643012
-
Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis
-
Wang, T.; Gilkes, D.M.; Takano, N.; Xiang, L.; Luo, W.; Bishop, C. J.; Chaturvedi, P.; Green, J.J.; Semenza, G. L. Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis. Proc. Natl. Acad. Sci. USA, 2014, 111(31), E3234-E3242.
-
(2014)
Proc. Natl. Acad. Sci. USA
, vol.111
, Issue.31
, pp. E3234-E3242
-
-
Wang, T.1
Gilkes, D.M.2
Takano, N.3
Xiang, L.4
Luo, W.5
Bishop, C.J.6
Chaturvedi, P.7
Green, J.J.8
Semenza, G.L.9
-
31
-
-
84924021202
-
Caveolin-1 accumulation in the tongue cancer tumor microenvironment is significantly associated with poor prognosis: An in-vivo and in-vitro study
-
Vered, M.; Lehtonen, M.; Hotakainen, L.; Pirila, E.; Teppo, S.; Nyberg, P.; Sormunen, R.; Zlotogorski-Hurvitz, A.; Salo, T.; Dayan, D. Caveolin-1 accumulation in the tongue cancer tumor microenvironment is significantly associated with poor prognosis: an in-vivo and in-vitro study. BMC Cancer, 2015, 15, 25.
-
(2015)
BMC Cancer
, vol.15
, pp. 25
-
-
Vered, M.1
Lehtonen, M.2
Hotakainen, L.3
Pirila, E.4
Teppo, S.5
Nyberg, P.6
Sormunen, R.7
Zlotogorski-Hurvitz, A.8
Salo, T.9
Dayan, D.10
-
32
-
-
84897062699
-
Exosomal proteome profiling: A potential multi-marker cellular phenotyping tool to characterize hypoxia-induced radiation resistance in breast cancer
-
Thomas, S. N.; Liao, Z., Clark, D.; Chen, Y.; Samadani, R.; Mao, L.; Ann, D. K.; K; Baulch, J. E.; Shapiro, P.; Yang, A. J. Exosomal proteome profiling: a potential multi-marker cellular phenotyping tool to characterize hypoxia-induced radiation resistance in breast cancer. Proteomes, 2013, 1(2), 87-108.
-
(2013)
Proteomes
, vol.1
, Issue.2
, pp. 87-108
-
-
Thomas, S.N.1
Liao, Z.2
Clark, D.3
Chen, Y.4
Samadani, R.5
Mao, L.6
Ann, D.K.7
Baulch, J.E.8
Shapiro, P.9
Yang, A.J.10
|