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Volumn 64, Issue 4, 2016, Pages 908-915

Effects of glucagon-like peptide-1 on glucagon secretion in patients with non-alcoholic fatty liver disease

Author keywords

Endogenous glucose production; Energy metabolism; Glucagon; Glucagon like peptide 1 (GLP 1); Lipolysis; Non alcoholic fatty liver disease (NAFLD)

Indexed keywords

GLUCAGON LIKE PEPTIDE 1; INSULIN; PLACEBO; STABLE ISOTOPE; GLUCAGON; GLUCOSE;

EID: 84955593210     PISSN: 01688278     EISSN: 16000641     Source Type: Journal    
DOI: 10.1016/j.jhep.2015.11.014     Document Type: Article
Times cited : (23)

References (47)
  • 1
    • 21344449292 scopus 로고    scopus 로고
    • Prevalence of and risk factors for nonalcoholic fatty liver disease: The Dionysos nutrition and liver study
    • G. Bedogni, L. Miglioli, F. Masutti, C. Tiribelli, G. Marchesini, and S. Bellentani Prevalence of and risk factors for nonalcoholic fatty liver disease: the Dionysos nutrition and liver study Hepatology 42 2005 44 52
    • (2005) Hepatology , vol.42 , pp. 44-52
    • Bedogni, G.1    Miglioli, L.2    Masutti, F.3    Tiribelli, C.4    Marchesini, G.5    Bellentani, S.6
  • 4
    • 34247605492 scopus 로고    scopus 로고
    • Prevalence of nonalcoholic fatty liver disease and its association with cardiovascular disease among type 2 diabetic patients
    • G. Targher, L. Bertolini, R. Padovani, S. Rodella, R. Tessari, L. Zenari, and et al. Prevalence of nonalcoholic fatty liver disease and its association with cardiovascular disease among type 2 diabetic patients Diabetes Care 30 2007 1212 1218
    • (2007) Diabetes Care , vol.30 , pp. 1212-1218
    • Targher, G.1    Bertolini, L.2    Padovani, R.3    Rodella, S.4    Tessari, R.5    Zenari, L.6
  • 5
    • 77949822066 scopus 로고    scopus 로고
    • Inappropriate glucagon response after oral compared with isoglycemic intravenous glucose administration in patients with type 1 diabetes
    • K.J. Hare, T. Vilsbøll, J.J. Holst, and F.K. Knop Inappropriate glucagon response after oral compared with isoglycemic intravenous glucose administration in patients with type 1 diabetes Am J Physiol Endocrinol Metab 298 2010 E832 E837
    • (2010) Am J Physiol Endocrinol Metab , vol.298 , pp. E832-E837
    • Hare, K.J.1    Vilsbøll, T.2    Holst, J.J.3    Knop, F.K.4
  • 6
    • 0023589251 scopus 로고
    • Role of hyperglucagonemia in maintenance of increased rates of hepatic glucose output in type II diabetics
    • A.D. Baron, L. Schaeffer, P. Shragg, and O.G. Kolterman Role of hyperglucagonemia in maintenance of increased rates of hepatic glucose output in type II diabetics Diabetes 36 1987 274 283
    • (1987) Diabetes , vol.36 , pp. 274-283
    • Baron, A.D.1    Schaeffer, L.2    Shragg, P.3    Kolterman, O.G.4
  • 7
    • 84899721201 scopus 로고    scopus 로고
    • Glucose-induced glucagon-like Peptide 1 secretion is deficient in patients with non-alcoholic Fatty liver disease
    • C. Bernsmeier, A.C. Meyer-Gerspach, L.S. Blaser, L. Jeker, R.E. Steinert, M.H. Heim, and et al. Glucose-induced glucagon-like Peptide 1 secretion is deficient in patients with non-alcoholic Fatty liver disease PLoS One 9 2014 e87488
    • (2014) PLoS One , vol.9 , pp. e87488
    • Bernsmeier, C.1    Meyer-Gerspach, A.C.2    Blaser, L.S.3    Jeker, L.4    Steinert, R.E.5    Heim, M.H.6
  • 8
    • 33845919110 scopus 로고    scopus 로고
    • Glucagon receptor knockout mice are resistant to diet-induced obesity and streptozotocin-mediated beta cell loss and hyperglycaemia
    • S.L. Conarello, G. Jiang, J. Mu, Z. Li, J. Woods, E. Zycband, and et al. Glucagon receptor knockout mice are resistant to diet-induced obesity and streptozotocin-mediated beta cell loss and hyperglycaemia Diabetologia 50 2007 142 150
    • (2007) Diabetologia , vol.50 , pp. 142-150
    • Conarello, S.L.1    Jiang, G.2    Mu, J.3    Li, Z.4    Woods, J.5    Zycband, E.6
  • 10
    • 77954250537 scopus 로고    scopus 로고
    • The glucagonostatic and insulinotropic effects of glucagon-like peptide 1 contribute equally to its glucose-lowering action
    • K.J. Hare, T. Vilsbøll, M. Asmar, C.F. Deacon, F.K. Knop, and J.J. Holst The glucagonostatic and insulinotropic effects of glucagon-like peptide 1 contribute equally to its glucose-lowering action Diabetes 59 2010 1765 1770
    • (2010) Diabetes , vol.59 , pp. 1765-1770
    • Hare, K.J.1    Vilsbøll, T.2    Asmar, M.3    Deacon, C.F.4    Knop, F.K.5    Holst, J.J.6
  • 11
    • 0038121744 scopus 로고    scopus 로고
    • Both GLP-1 and GIP are insulinotropic at basal and postprandial glucose levels and contribute nearly equally to the incretin effect of a meal in healthy subjects
    • T. Vilsbøll, T. Krarup, S. Madsbad, and J.J. Holst Both GLP-1 and GIP are insulinotropic at basal and postprandial glucose levels and contribute nearly equally to the incretin effect of a meal in healthy subjects Regul Pept 114 2003 115 121
    • (2003) Regul Pept , vol.114 , pp. 115-121
    • Vilsbøll, T.1    Krarup, T.2    Madsbad, S.3    Holst, J.J.4
  • 12
    • 79959781838 scopus 로고    scopus 로고
    • Loss of incretin effect is a specific, important, and early characteristic of type 2 diabetes
    • J.J. Holst, F.K. Knop, T. Vilsbøll, T. Krarup, and S. Madsbad Loss of incretin effect is a specific, important, and early characteristic of type 2 diabetes Diabetes Care 34 2011 S251 S257
    • (2011) Diabetes Care , vol.34 , pp. S251-S257
    • Holst, J.J.1    Knop, F.K.2    Vilsbøll, T.3    Krarup, T.4    Madsbad, S.5
  • 13
    • 73249122913 scopus 로고    scopus 로고
    • Preserved inhibitory potency of GLP-1 on glucagon secretion in type 2 diabetes mellitus
    • K.J. Hare, F.K. Knop, M. Asmar, S. Madsbad, C.F. Deacon, J.J. Holst, and et al. Preserved inhibitory potency of GLP-1 on glucagon secretion in type 2 diabetes mellitus J Clin Endocrinol Metab 94 2009 4679 4687
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 4679-4687
    • Hare, K.J.1    Knop, F.K.2    Asmar, M.3    Madsbad, S.4    Deacon, C.F.5    Holst, J.J.6
  • 14
    • 20044374023 scopus 로고    scopus 로고
    • Design and validation of a histological scoring system for nonalcoholic fatty liver disease
    • D.E. Kleiner, E.M. Brunt, M. Van Natta, C. Behling, M.J. Contos, O.W. Cummings, and et al. Design and validation of a histological scoring system for nonalcoholic fatty liver disease Hepatology 41 2005 1313 1321
    • (2005) Hepatology , vol.41 , pp. 1313-1321
    • Kleiner, D.E.1    Brunt, E.M.2    Van Natta, M.3    Behling, C.4    Contos, M.J.5    Cummings, O.W.6
  • 15
    • 84895779656 scopus 로고    scopus 로고
    • Glucose-dependent insulinotropic polypeptide: Blood glucose stabilizing effects in patients with type 2 diabetes
    • M.B. Christensen, S. Calanna, J.J. Holst, T. Vilsbøll, and F.K. Knop Glucose-dependent insulinotropic polypeptide: blood glucose stabilizing effects in patients with type 2 diabetes J Clin Endocrinol Metab 99 2014 E418 E426
    • (2014) J Clin Endocrinol Metab , vol.99 , pp. E418-E426
    • Christensen, M.B.1    Calanna, S.2    Holst, J.J.3    Vilsbøll, T.4    Knop, F.K.5
  • 16
    • 84945061771 scopus 로고
    • A general regression procedure for method transformation. Application of linear regression procedures for method comparison studies in clinical chemistry, Part III
    • W. Bablok, H. Passing, R. Bender, and B. Schneider A general regression procedure for method transformation. Application of linear regression procedures for method comparison studies in clinical chemistry, Part III J Clin Chem Clin Biochem 26 1988 783 790
    • (1988) J Clin Chem Clin Biochem , vol.26 , pp. 783-790
    • Bablok, W.1    Passing, H.2    Bender, R.3    Schneider, B.4
  • 17
    • 0026027919 scopus 로고
    • Proglucagon products in plasma of noninsulin-dependent diabetics and nondiabetic controls in the fasting state and after oral glucose and intravenous arginine
    • C. Orskov, J. Jeppesen, S. Madsbad, and J.J. Holst Proglucagon products in plasma of noninsulin-dependent diabetics and nondiabetic controls in the fasting state and after oral glucose and intravenous arginine J Clin Invest 87 1991 415 423
    • (1991) J Clin Invest , vol.87 , pp. 415-423
    • Orskov, C.1    Jeppesen, J.2    Madsbad, S.3    Holst, J.J.4
  • 18
    • 0028281773 scopus 로고
    • Tissue and plasma concentrations of amidated and glycine-extended glucagon-like peptide i in humans
    • C. Orskov, L. Rabenhøj, A. Wettergren, H. Kofod, and J.J. Holst Tissue and plasma concentrations of amidated and glycine-extended glucagon-like peptide I in humans Diabetes 43 1994 535 539
    • (1994) Diabetes , vol.43 , pp. 535-539
    • Orskov, C.1    Rabenhøj, L.2    Wettergren, A.3    Kofod, H.4    Holst, J.J.5
  • 20
    • 77049274176 scopus 로고
    • Measurement of size and turnover rate of body glucose pool by the isotope dilution method
    • R. Steele, J.S. Wall, R.C. De Bodo, and N. Altszuler Measurement of size and turnover rate of body glucose pool by the isotope dilution method Am J Physiol 187 1956 15 24
    • (1956) Am J Physiol , vol.187 , pp. 15-24
    • Steele, R.1    Wall, J.S.2    De Bodo, R.C.3    Altszuler, N.4
  • 21
    • 0027378025 scopus 로고
    • Regulation of endogenous fat and carbohydrate metabolism in relation to exercise intensity and duration
    • J.A. Romijn, E.F. Coyle, L.S. Sidossis, A. Gastaldelli, J.F. Horowitz, E. Endert, and et al. Regulation of endogenous fat and carbohydrate metabolism in relation to exercise intensity and duration Am J Physiol 265 1993 E380 E391
    • (1993) Am J Physiol , vol.265 , pp. E380-E391
    • Romijn, J.A.1    Coyle, E.F.2    Sidossis, L.S.3    Gastaldelli, A.4    Horowitz, J.F.5    Endert, E.6
  • 22
    • 0023930822 scopus 로고
    • The theoretical bases of indirect calorimetry: A review
    • E. Ferrannini The theoretical bases of indirect calorimetry: a review Metab Clin Exp 37 1988 287 301
    • (1988) Metab Clin Exp , vol.37 , pp. 287-301
    • Ferrannini, E.1
  • 23
    • 0026504160 scopus 로고
    • Estimation of insulin secretion rates from C-peptide levels. Comparison of individual and standard kinetic parameters for C-peptide clearance
    • E. Van Cauter, F. Mestrez, J. Sturis, and K.S. Polonsky Estimation of insulin secretion rates from C-peptide levels. Comparison of individual and standard kinetic parameters for C-peptide clearance Diabetes 41 1992 368 377
    • (1992) Diabetes , vol.41 , pp. 368-377
    • Van Cauter, E.1    Mestrez, F.2    Sturis, J.3    Polonsky, K.S.4
  • 24
    • 84901623578 scopus 로고    scopus 로고
    • Relationship between disease severity, hyperinsulinemia, and impaired insulin clearance in patients with nonalcoholic steatohepatitis
    • F. Bril, R. Lomonaco, B. Orsak, C. Ortiz-Lopez, A. Webb, F. Tio, and et al. Relationship between disease severity, hyperinsulinemia, and impaired insulin clearance in patients with nonalcoholic steatohepatitis Hepatology 59 2014 2178 2187
    • (2014) Hepatology , vol.59 , pp. 2178-2187
    • Bril, F.1    Lomonaco, R.2    Orsak, B.3    Ortiz-Lopez, C.4    Webb, A.5    Tio, F.6
  • 25
    • 0036796175 scopus 로고    scopus 로고
    • Portal glucose infusion exerts an incretin effect associated with changes in pancreatic neural activity in conscious dogs
    • B.E. Dunning, M.C. Moore, T. Ikeda, D.W. Neal, M.F. Scott, and A.D. Cherrington Portal glucose infusion exerts an incretin effect associated with changes in pancreatic neural activity in conscious dogs Metab Clin Exp 51 2002 1324 1330
    • (2002) Metab Clin Exp , vol.51 , pp. 1324-1330
    • Dunning, B.E.1    Moore, M.C.2    Ikeda, T.3    Neal, D.W.4    Scott, M.F.5    Cherrington, A.D.6
  • 26
    • 84859404868 scopus 로고    scopus 로고
    • Role of obesity and lipotoxicity in the development of nonalcoholic steatohepatitis: Pathophysiology and clinical implications
    • K. Cusi Role of obesity and lipotoxicity in the development of nonalcoholic steatohepatitis: pathophysiology and clinical implications Gastroenterology 142 2012 e6 10.1053/j.gastro.2012.02.003
    • (2012) Gastroenterology , vol.142 , pp. e6
    • Cusi, K.1
  • 27
    • 57949116523 scopus 로고    scopus 로고
    • Alterations in fatty acid kinetics in obese adolescents with increased intrahepatic triglyceride content
    • E. Fabbrini, D. deHaseth, S. Deivanayagam, B.S. Mohammed, B.E. Vitola, and S. Klein Alterations in fatty acid kinetics in obese adolescents with increased intrahepatic triglyceride content Obesity (Silver Spring) 17 2009 25 29 10.1038/oby.2008.494
    • (2009) Obesity (Silver Spring) , vol.17 , pp. 25-29
    • Fabbrini, E.1    DeHaseth, D.2    Deivanayagam, S.3    Mohammed, B.S.4    Vitola, B.E.5    Klein, S.6
  • 28
    • 84859942552 scopus 로고    scopus 로고
    • Effect of adipose tissue insulin resistance on metabolic parameters and liver histology in obese patients with nonalcoholic fatty liver disease
    • R. Lomonaco, C. Ortiz-Lopez, B. Orsak, A. Webb, J. Hardies, C. Darland, and et al. Effect of adipose tissue insulin resistance on metabolic parameters and liver histology in obese patients with nonalcoholic fatty liver disease Hepatology 55 2012 1389 1397
    • (2012) Hepatology , vol.55 , pp. 1389-1397
    • Lomonaco, R.1    Ortiz-Lopez, C.2    Orsak, B.3    Webb, A.4    Hardies, J.5    Darland, C.6
  • 29
    • 84860242081 scopus 로고    scopus 로고
    • Impaired incretin effect and fasting hyperglucagonaemia characterizing type 2 diabetic subjects are early signs of dysmetabolism in obesity
    • F.K. Knop, K. Aaboe, T. Vilsbøll, A. Vølund, J.J. Holst, T. Krarup, and et al. Impaired incretin effect and fasting hyperglucagonaemia characterizing type 2 diabetic subjects are early signs of dysmetabolism in obesity Diabetes Obes Metab 14 2012 500 510
    • (2012) Diabetes Obes Metab , vol.14 , pp. 500-510
    • Knop, F.K.1    Aaboe, K.2    Vilsbøll, T.3    Vølund, A.4    Holst, J.J.5    Krarup, T.6
  • 30
    • 34848862525 scopus 로고    scopus 로고
    • Association of fasting glucagon and proinsulin concentrations with insulin resistance
    • E. Ferrannini, E. Muscelli, A. Natali, R. Gabriel, A. Mitrakou, A. Flyvbjerg, and et al. Association of fasting glucagon and proinsulin concentrations with insulin resistance Diabetologia 50 2007 2342 2347
    • (2007) Diabetologia , vol.50 , pp. 2342-2347
    • Ferrannini, E.1    Muscelli, E.2    Natali, A.3    Gabriel, R.4    Mitrakou, A.5    Flyvbjerg, A.6
  • 32
    • 77950505046 scopus 로고    scopus 로고
    • Metabolic disturbances in liver cirrhosis: Hepatogenous diabetes
    • [Author reply 716]
    • W. Nolte Metabolic disturbances in liver cirrhosis: hepatogenous diabetes Dtsch Med Wochenschr 135 2010 716 [Author reply 716]
    • (2010) Dtsch Med Wochenschr , vol.135 , pp. 716
    • Nolte, W.1
  • 33
    • 23644442053 scopus 로고    scopus 로고
    • Evidence of hepatic glucagon resistance associated with hepatic steatosis: Reversal effect of training
    • A. Charbonneau, K. Couturier, M.-S. Gauthier, and J.-M. Lavoie Evidence of hepatic glucagon resistance associated with hepatic steatosis: reversal effect of training Int J Sports Med 26 2005 432 441
    • (2005) Int J Sports Med , vol.26 , pp. 432-441
    • Charbonneau, A.1    Couturier, K.2    Gauthier, M.-S.3    Lavoie, J.-M.4
  • 34
    • 33846994380 scopus 로고    scopus 로고
    • High-fat diet-induced hepatic steatosis reduces glucagon receptor content in rat hepatocytes: Potential interaction with acute exercise
    • A. Charbonneau, C.G. Unson, and J.-M. Lavoie High-fat diet-induced hepatic steatosis reduces glucagon receptor content in rat hepatocytes: potential interaction with acute exercise J Physiol (Lond) 579 2007 255 267
    • (2007) J Physiol (Lond) , vol.579 , pp. 255-267
    • Charbonneau, A.1    Unson, C.G.2    Lavoie, J.-M.3
  • 35
    • 0842288445 scopus 로고    scopus 로고
    • Reduction in glucagon receptor expression by an antisense oligonucleotide ameliorates diabetic syndrome in db/db mice
    • Y. Liang, M.C. Osborne, B.P. Monia, S. Bhanot, W.A. Gaarde, C. Reed, and et al. Reduction in glucagon receptor expression by an antisense oligonucleotide ameliorates diabetic syndrome in db/db mice Diabetes 53 2004 410 417
    • (2004) Diabetes , vol.53 , pp. 410-417
    • Liang, Y.1    Osborne, M.C.2    Monia, B.P.3    Bhanot, S.4    Gaarde, W.A.5    Reed, C.6
  • 37
    • 84875478761 scopus 로고    scopus 로고
    • Liver-specific disruption of the murine glucagon receptor produces α-cell hyperplasia: Evidence for a circulating α-cell growth factor
    • C. Longuet, A.M. Robledo, E.D. Dean, C. Dai, S. Ali, I. McGuinness, and et al. Liver-specific disruption of the murine glucagon receptor produces α-cell hyperplasia: evidence for a circulating α-cell growth factor Diabetes 62 2013 1196 1205
    • (2013) Diabetes , vol.62 , pp. 1196-1205
    • Longuet, C.1    Robledo, A.M.2    Dean, E.D.3    Dai, C.4    Ali, S.5    McGuinness, I.6
  • 39
    • 0037385959 scopus 로고    scopus 로고
    • Islet beta-cell secretion determines glucagon release from neighbouring alpha-cells
    • H. Ishihara, P. Maechler, A. Gjinovci, P.-L. Herrera, and C.B. Wollheim Islet beta-cell secretion determines glucagon release from neighbouring alpha-cells Nat Cell Biol 5 2003 330 335
    • (2003) Nat Cell Biol , vol.5 , pp. 330-335
    • Ishihara, H.1    Maechler, P.2    Gjinovci, A.3    Herrera, P.-L.4    Wollheim, C.B.5
  • 40
    • 0029954211 scopus 로고    scopus 로고
    • Glucagonostatic actions and reduction of fasting hyperglycemia by exogenous glucagon-like peptide I(7-36) amide in type i diabetic patients
    • W.O. Creutzfeldt, N. Kleine, B. Willms, C. Orskov, J.J. Holst, and M.A. Nauck Glucagonostatic actions and reduction of fasting hyperglycemia by exogenous glucagon-like peptide I(7-36) amide in type I diabetic patients Diabetes Care 19 1996 580 586
    • (1996) Diabetes Care , vol.19 , pp. 580-586
    • Creutzfeldt, W.O.1    Kleine, N.2    Willms, B.3    Orskov, C.4    Holst, J.J.5    Nauck, M.A.6
  • 41
    • 55649108863 scopus 로고    scopus 로고
    • Glucagon-like peptide-1, but not glucose-dependent insulinotropic peptide, inhibits glucagon secretion via somatostatin (receptor subtype 2) in the perfused rat pancreas
    • J. De Heer, C. Rasmussen, D.H. Coy, and J.J. Holst Glucagon-like peptide-1, but not glucose-dependent insulinotropic peptide, inhibits glucagon secretion via somatostatin (receptor subtype 2) in the perfused rat pancreas Diabetologia 51 2008 2263 2270
    • (2008) Diabetologia , vol.51 , pp. 2263-2270
    • De Heer, J.1    Rasmussen, C.2    Coy, D.H.3    Holst, J.J.4
  • 44
    • 84926209832 scopus 로고    scopus 로고
    • Metabolic inflexibility and insulin resistance in obese adolescents with non-alcoholic fatty liver disease
    • S. Lee, M. Rivera-Vega, H.M.A.A. Alsayed, C. Boesch, and I. Libman Metabolic inflexibility and insulin resistance in obese adolescents with non-alcoholic fatty liver disease Pediatr Diabetes 16 2015 211 218
    • (2015) Pediatr Diabetes , vol.16 , pp. 211-218
    • Lee, S.1    Rivera-Vega, M.2    Alsayed, H.M.A.A.3    Boesch, C.4    Libman, I.5
  • 45
    • 0023618126 scopus 로고
    • Role of lipid oxidation in pathogenesis of insulin resistance of obesity and type II diabetes
    • J.P. Felber, E. Ferrannini, A. Golay, H.U. Meyer, D. Theibaud, B. Curchod, and et al. Role of lipid oxidation in pathogenesis of insulin resistance of obesity and type II diabetes Diabetes 36 1987 1341 1350
    • (1987) Diabetes , vol.36 , pp. 1341-1350
    • Felber, J.P.1    Ferrannini, E.2    Golay, A.3    Meyer, H.U.4    Theibaud, D.5    Curchod, B.6
  • 46
    • 33750093045 scopus 로고    scopus 로고
    • Higher fasting plasma concentrations of glucagon-like peptide 1 are associated with higher resting energy expenditure and fat oxidation rates in humans
    • N. Pannacciulli, J.C. Bunt, J. Koska, C. Bogardus, and J. Krakoff Higher fasting plasma concentrations of glucagon-like peptide 1 are associated with higher resting energy expenditure and fat oxidation rates in humans Am J Clin Nutr 84 2006 556 560
    • (2006) Am J Clin Nutr , vol.84 , pp. 556-560
    • Pannacciulli, N.1    Bunt, J.C.2    Koska, J.3    Bogardus, C.4    Krakoff, J.5


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