SiRNA-mediated serotonin transporter knockdown in the dorsal raphe nucleus rescues single prolonged stress-induced hippocampal autophagy in rats

Journal of the Neurological Sciences

Volumn 360, Issue , 2016, Pages 133-140

  Wu, Zhong Min ^a,d   Zheng, Chun Hua ^b   Zhu, Zhen Hua ^c   Wu, Feng Tian ^e   Ni, Gui Lian ^d   Liang, Yong ^a  

^a TAIZHOU UNIVERSITY   (China)

^b TAIZHOU HOSPITAL OF ZHEJIANG PROVINCE   (China)

^c Tai Zhou Central Hospital   (China)

^d First People's Hospital of Linhai City   (China)

^e ZHEJIANG UNIVERSITY CITY COLLEGE   (China)

Author keywords

Dorsal raphe nucleus; Hippocampal autophagy; Post traumatic stress disorder; Serotonin transporter; Small interfering RNA

Indexed keywords

BECLIN 1; CORTICOSTERONE; LC3 1 PROTEIN; LC3 2 PROTEIN; PROTEIN; SEROTONIN; SEROTONIN TRANSPORTER; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; APOPTOSIS REGULATORY PROTEIN; BECN1 PROTEIN, RAT; LC3 PROTEIN, RAT; MICROTUBULE ASSOCIATED PROTEIN;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPHAGY; CONDITIONING; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; DENTATE GYRUS; DORSAL RAPHE NUCLEUS; FEAR; GENE SILENCING; HIPPOCAMPAL CA1 REGION; HIPPOCAMPAL CA2 REGION; HIPPOCAMPAL CA3 REGION; HIPPOCAMPUS; LATENT PERIOD; MALE; NONHUMAN; POSTTRAUMATIC STRESS DISORDER; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REINFORCEMENT; WESTERN BLOTTING; ANIMAL; GENETICS; MENTAL STRESS; METABOLISM; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

ANIMALS; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; BECLIN-1; BEHAVIOR, ANIMAL; DORSAL RAPHE NUCLEUS; EXTINCTION, PSYCHOLOGICAL; FEAR; HIPPOCAMPUS; MALE; MICROTUBULE-ASSOCIATED PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; RNA, SMALL INTERFERING; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; STRESS, PSYCHOLOGICAL;

EID: 84955475259     PISSN: 0022510X     EISSN: 18785883     Source Type: Journal    
DOI: 10.1016/j.jns.2015.11.056     Document Type: Article

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