The protective role of isorhamnetin on human brain microvascular endothelial cells from cytotoxicity induced by methylglyoxal and oxygen-glucose deprivation

Journal of Neurochemistry

Volumn 136, Issue 3, 2016, Pages 651-659

  Li, Wenlu ^a,b   Chen, Zhigang ^a,c   Yan, Min ^a   He, Ping ^a   Chen, Zhong ^b   Dai, Haibin ^a,c  

^a ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b ZHEJIANG UNIVERSITY   (China)

^c ZHEJIANG UNIVERSITY   (China)

Author keywords

Fas FasL; isorhamnetin; methylglyoxal; oxygen glucose deprivation; primary human brain microvascular endothelial cells

Indexed keywords

CASPASE 3; CASPASE 8; CASPASE 9; FAS ANTIGEN; FAS LIGAND; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1 RECEPTOR; ISORHAMNETIN; METHYLGLYOXAL; PROTEIN BCL 2; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; 3-METHYLQUERCETIN; CASPASE; GLUCOSE; NEUROPROTECTIVE AGENT; OXYGEN; QUERCETIN; REACTIVE OXYGEN METABOLITE;

ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; BRAIN CAPILLARY ENDOTHELIAL CELL; BRAIN PROTECTION; CELL PROTECTION; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; DRUG MECHANISM; ENZYME ACTIVITY; GLUCOSE METABOLISM; HUMAN; HUMAN CELL; OXYGEN GLUCOSE DEPRIVATION; PRIORITY JOURNAL; PROCEDURES CONCERNING CELLS; PROTEIN EXPRESSION; ANALOGS AND DERIVATIVES; BRAIN; CYTOLOGY; DEFICIENCY; DOSE RESPONSE; DRUG EFFECTS; ENDOTHELIUM CELL; GENE EXPRESSION REGULATION; METABOLISM;

APOPTOSIS; BRAIN; CASPASES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; FAS LIGAND PROTEIN; GENE EXPRESSION REGULATION; GLUCOSE; HUMANS; NEUROPROTECTIVE AGENTS; NF-KAPPA B; OXYGEN; PYRUVALDEHYDE; QUERCETIN; REACTIVE OXYGEN SPECIES; RECEPTORS, INTERLEUKIN-1;

EID: 84955416708     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/jnc.13436     Document Type: Article

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