Underlying neural mechanisms of mirror therapy: Implications for motor rehabilitation in stroke

Neurology India

Volumn 64, Issue 1, 2016, Pages 38-44

  Arya, Kamal Narayan ^a  

^a Department of Physiotherapy   (India)

Author keywords

Brain stimulation; cerebrovasular accident; cortical reorganization; motor control neuroplasticity

Indexed keywords

BRAIN DAMAGE; CEREBELLUM; CEREBROVASCULAR ACCIDENT; CORPUS CALLOSUM; FRONTAL LOBE; HUMAN; INTERVENTION STUDY; MIRROR NEURON; MIRROR THERAPY; NERVE CELL PLASTICITY; NEUROMODULATION; OCCIPITAL LOBE; PARESIS; PREMOTOR CORTEX; PRIMARY MOTOR CORTEX; PRIMARY SOMATOSENSORY CORTEX; REHABILITATION CARE; REVIEW; BRAIN; CONVALESCENCE; HEMISPHERIC DOMINANCE; ILLUSION; MOTOR CORTEX; MOVEMENT (PHYSIOLOGY); PATHOPHYSIOLOGY; PHYSIOLOGY; STROKE REHABILITATION;

BRAIN; FUNCTIONAL LATERALITY; HUMANS; ILLUSIONS; MIRROR NEURONS; MOTOR CORTEX; MOVEMENT; RECOVERY OF FUNCTION; STROKE REHABILITATION;

EID: 84955325192     PISSN: 00283886     EISSN: 19984022     Source Type: Journal    
DOI: 10.4103/0028-3886.173622     Document Type: Review

References (48)

1. Ramachandran VS, Rogers-Ramachandran D. Synaesthesia in phantom limbs induced with mirrors. Proc Biol Sci 1996;263:377-86
2. Arya KN, Pandian S, Kumar D, Puri V. Task-based mirror therapy augmenting motor recovery in poststroke hemiparesis: A randomized controlled trial. J Stroke Cerebrovasc Dis 2015;24:1738-48
3. Samuelkamaleshkumar S, Reethajanetsureka S, Pauljebaraj P, Benshamir B, Padankatti SM, David JA. Mirror therapy enhances motor performance in the paretic upper limb after stroke: A pilot randomized controlled trial. Arch Phys Med Rehabil 2014;95:2000-5
4. Arya KN, Pandian S. Effect of task-based mirror therapy on motor recovery of the upper extremity in chronic stroke patients: A pilot study. Top Stroke Rehabil 2013;20:210-7
5. Bartur G, Pratt H, Dickstein R, Frenkel-Toledo S, Geva A, Soroker N. Electrophysiological manifestations of mirror visual feedback during manual movement. Brain Res 2015;1606:113-24
6. Furukawa K, Suzuki H, Fukuda J. Motion of the drawing hand induces a progressive increase in muscle activity of the non-dominant hand in Ramachandran's mirror-box therapy. J Rehabil Med 2012;44:939-43
7. Michielsen ME, Selles RW, van der Geest JN, Eckhardt M, Yavuzer G, Stam HJ, et al. Motor recovery and cortical reorganization after mirror therapy in chronic stroke patients: A phase II randomized controlled trial. Neurorehabil Neural Repair 2011;25:223-33
8. Michielsen ME, Smits M, Ribbers GM, Stam HJ, van der Geest JN, Bussmann JB, et al. The neuronal correlates of mirror therapy: An fMRI study on mirror induced visual illusions in patients with stroke. J Neurol Neurosurg Psychiatry 2011;82:393-8
9. Rossiter HE, Borrelli MR, Borchert RJ, Bradbury D, Ward NS. Cortical mechanisms of mirror therapy after stroke. Neurorehabil Neural Repair 2015;29:444-52
10. Hamzei F, Läppchen CH, Glauche V, Mader I, Rijntjes M, Weiller C. Functional plasticity induced by mirror training: The mirror as the element connecting both hands to one hemisphere. Neurorehabil Neural Repair 2012;26:484-96
11. Shumway-Cook A, Woollacott MH. Motor control: Translating Research into Clinical Practice. Lippincott Williams and Wilkins; 2007
12. Tanji J, Mushiake H. Comparison of neuronal activity in the supplementary motor area and primary motor cortex. Brain Res Cogn Brain Res 1996;3:143-50
13. Pavlova OG. Primary motor cortex as one of the levels of the construction of movements. Zh Vyssh Nerv Deiat Im I P Pavlova 2014;64:600-14
14. Stein J, Harvey RL, Macko RF, Winstein CJ, Zorowitz RD. Stroke recovery and rehabilitation. New York, NY: Demos Publishing Company; 2009
15. Pandian S, Arya KN. Motor impairment of the ipsilesional body side in poststroke subjects. J Bodyw Mov Ther 2013;17:495-503
16. Pandian S, Arya KN, Kumar D. Effect of motor training involving the less-affected side (MTLA) in post-stroke subjects: A pilot randomized controlled trial. Top Stroke Rehabil 2015;22:357-67
17. Abela E, Seiler A, Missimer JH, Federspiel A, Hess CW, Sturzenegger M, et al. Grey matter volumetric changes related to recovery from hand paresis after cortical sensorimotor stroke. Brain Struct Funct 2015;220:2533-50
18. Simis M, Adeyemo BO, Medeiros LF, Miraval F, Gagliardi RJ, Fregni F. Motor cortex-induced plasticity by noninvasive brain stimulation: A comparison between transcranial direct current stimulation and transcranial magnetic stimulation. Neuroreport 2013;24:973-5
19. Ramachandran VS, Altschuler EL. The use of visual feedback, in particular mirror visual feedback, in restoring brain function. Brain 2009;132:1693-710
20. Mirela Cristina L, Matei D, Ignat B, Popescu CD. Mirror therapy enhances upper extremity motor recovery in stroke patients. Acta Neurol Belg 2015;115:597-603
21. Ji SG, Kim MK. The effects of mirror therapy on the gait of subacute stroke patients: A randomized controlled trial. Clin Rehabil 2015;29:348-54
22. Harmsen WJ, Bussmann JB, Selles RW, Hurkmans HL, Ribbers GM. A mirror therapy-based action observation protocol to improve motor learning after stroke. Neurorehabil Neural Repair 2015;29:509-16
23. Yavuzer G, Selles R, Sezer N, Sütbeyaz S, Bussmann JB, Köseoʇlu F, et al. Mirror therapy improves hand function in subacute stroke: A randomized controlled trial. Arch Phys Med Rehabil 2008;89:393-8
24. Thieme H, Mehrholz J, Pohl M, Behrens J, Dohle C. Mirror therapy for improving motor function after stroke. Stroke 2013;44:e1-2
25. von Rein E, Hoff M, Kaminski E, Sehm B, Steele CJ, Villringer A, et al. Improving motor performance without training: The effect of combining mirror visual feedback with transcranial direct current stimulation. J Neurophysiol 2015;113:2383-9
26. Lee YY, Lin KC, Wu CY, Liao CH, Lin JC, Chen CL. Combining afferent stimulation and mirror therapy for improving muscular, sensorimotor, and daily functions after chronic stroke: A randomized, placebo-controlled study. Am J Phys Med Rehabil 2015;94(Suppl 1):859-68
27. Lin KC, Chen YT, Huang PC, Wu CY, Huang WL, Yang HW, et al. Effect of mirror therapy combined with somatosensory stimulation on motor recovery and daily function in stroke patients: A pilot study. J Formos Med Assoc 2014;113:422-8
28. Sutbeyaz S, Yavuzer G, Sezer N, Koseoglu BF. Mirror therapy enhances lower-extremity motor recovery and motor functioning after stroke: A randomized controlled trial. Arch Phys Med Rehabil 2007;88:555-9
29. Milde C, Rance M, Kirsch P, Trojan J, Fuchs X, Foell J, et al. Do mirror glasses have the same effect on brain activity as a mirror box? Evidence from a functional magnetic resonance imaging study with healthy subjects. PLoS One 2015;10:e0127694
30. Wang J, Fritzsch C, Bernarding J, Holtze S, Mauritz KH, Brunetti M, et al. A comparison of neural mechanisms in mirror therapy and movement observation therapy. J Rehabil Med 2013;45:410-3
31. Garry MI, Loftus A, Summers JJ. Mirror, mirror on the wall: Viewing a mirror reflection of unilateral hand movements facilitates ipsilateral M1 excitability. Exp Brain Res 2005;163:118-22
32. Hadoush H, Mano H, Sunagawa T, Nakanishi K, Ochi M. Optimization of mirror therapy to excite ipsilateral primary motor cortex. NeuroRehabilitation 2013;32:617-24
33. Nojima I, Mima T, Koganemaru S, Thabit MN, Fukuyama H, Kawamata T. Human motor plasticity induced by mirror visual feedback. J Neurosci 2012;32:1293-300
34. Fukumura K, Sugawara K, Tanabe S, Ushiba J, Tomita Y. Influence of mirror therapy on human motor cortex. Int J Neurosci 2007;117:1039-48
35. Tominaga W, Matsubayashi J, Deguchi Y, Minami C, Kinai T, Nakamura M, et al. A mirror reflection of a hand modulates stimulus-induced 20-Hz activity. Neuroimage 2009;46:500-4
36. Numata K, Murayama T, Takasugi J, Monma M, Oga M. Mirror observation of finger action enhances activity in anterior intraparietal sulcus: A functional magnetic resonance imaging study. J Jpn Phys Ther Assoc 2013;16:1-6
37. Matthys K, Smits M, Van der Geest JN, Van der Lugt A, Seurinck R, Stam HJ, et al. Mirror-induced visual illusion of hand movements: A functional magnetic resonance imaging study. Arch Phys Med Rehabil 2009;90:675-81
38. Lappchen CH, Ringer T, Blessin J, Seidel G, Grieshammer S, Lange R, et al. Optical illusion alters M1 excitability after mirror therapy: A TMS study. J Neurophysiol 2012;108:2857-61
39. Butorina A, Prokofyev A, Nazarova M, Litvak V, Stroganova T. The mirror illusion induces high gamma oscillations in the absence of movement. Neuroimage 2014;103:181-91
40. Fritzsch C, Wang J, Dos Santos LF, Mauritz KH, Brunetti M, Dohle C. Different effects of the mirror illusion on motor and somatosensory processing. Restor Neurol Neurosci 2014;32:269-80
41. Avanzino L, Raffo A, Pelosin E, Ogliastro C, Marchese R, Ruggeri P, et al. Training based on mirror visual feedback influences transcallosal communication. Eur J Neurosci 2014;40:2581-8
42. Nojima I, Oga T, Fukuyama H, Kawamata T, Mima T. Mirror visual feedback can induce motor learning in patients with callosal disconnection. Exp Brain Res 2013;227:79-83
43. Kang YJ, Ku J, Kim HJ, Park HK. Facilitation of corticospinal excitability according to motor imagery and mirror therapy in healthy subjects and stroke patients. Ann Rehabil Med 2011;35:747-58
44. Deconinck FJ, Smorenburg AR, Benham A, Ledebt A, Feltham MG, Savelsbergh GJ. Reflections on mirror therapy: A systematic review of the effect of mirror visual feedback on the brain. Neurorehabil Neural Repair 2015;29:349-61
45. Bhasin A, Padma Srivastava MV, Kumaran SS, Bhatia R, Mohanty S. Neural interface of mirror therapy in chronic stroke patients: A functional magnetic resonance imaging study. Neurol India 2012;60:570-6
46. Saleh S, Adamovich SV, Tunik E. Mirrored feedback in chronic stroke: Recruitment and effective connectivity of ipsilesional sensorimotor networks. Neurorehabil Neural Repair 2014;28:344-54
47. Carvalho D, Teixeira S, Lucas M, Yuan TF, Chaves F, Peressutti C, et al. The mirror neuron system in post-stroke rehabilitation. Int Arch Med 2013;6:41
48. Mehta UM, Waghmare AV, Thirthalli J, Venkatasubramanian G, Gangadhar BN. Is the human mirror neuron system plastic? Evidence from a transcranial magnetic stimulation study. Asian J Psychiatr 2015;17:71-7