Baeyer–Villiger monooxygenase-catalyzed desymmetrizations of cyclobutanones. Application to the synthesis of valuable spirolactones

Tetrahedron

Volumn 72, Issue 46, 2016, Pages 7268-7275

  Rodríguez Mata, María ^a   Lavandera, Iván ^a   Gotor Fernández, Vicente ^a   Gotor, Vicente ^a   García Cerrada, Susana ^b   Mendiola, Javier ^b   de Frutos, Óscar ^b   Collado, Iván ^b  

^a UNIVERSITY OF OVIEDO   (Spain)

^b ELI LILLY AND COMPANY   (Spain)

Author keywords

Asymmetric synthesis; Baeyer Villiger oxidation; Lactones; Oxygenases; Spiro compounds

Indexed keywords

ALCOHOL; ALCOHOL DEHYDROGENASE; CYCLOBUTANONE DERIVATIVE; GAMMA BUTYROLACTONE DERIVATIVE; LACTONE DERIVATIVE; SPIRONOLACTONE; UNSPECIFIC MONOOXYGENASE;

ARTICLE; BAEYER VILLIGER REACTION; BIOCATALYST; BIOTRANSFORMATION; CHIRALITY; ENANTIOMER; ENZYME MECHANISM; OXIDATION; PRIORITY JOURNAL; REACTION OPTIMIZATION; SYNTHESIS;

EID: 84955278504     PISSN: 00404020     EISSN: 14645416     Source Type: Journal    
DOI: 10.1016/j.tet.2015.12.071     Document Type: Article

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