Suppression of Brain Mast Cells Degranulation Inhibits Microglial Activation and Central Nervous System Inflammation

Molecular Neurobiology

Volumn 54, Issue 2, 2017, Pages 997-1007

  Dong, Hongquan ^a   Zhang, Xiang ^a   Wang, Yiming ^a   Zhou, Xiqiao ^a   Qian, Yanning ^a   Zhang, Shu ^a  

^a THE FIRST AFFILIATED HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

Author keywords

CNS immune inflammation; Compound 48 80; Cromolyn; Mast cell degranulation; Microglial activation

Indexed keywords

CROMOGLYCATE DISODIUM; CYTOKINE; HISTAMINE H1 RECEPTOR; HISTAMINE H4 RECEPTOR; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; PROTEINASE ACTIVATED RECEPTOR 2; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CELL INTERACTION; CENTRAL NERVOUS SYSTEM DISEASE; CENTRAL NERVOUS SYSTEM INFLAMMATION; CONTROLLED STUDY; ENCEPHALITIS; FLOW CYTOMETRY; HYPOTHALAMUS; IMMUNOHISTOCHEMISTRY; MALE; MAST CELL DEGRANULATION; MICROGLIA; MOLECULARLY TARGETED THERAPY; MOUSE; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PROTEIN EXPRESSION; RAT; WESTERN BLOTTING; ANIMAL; BRAIN; DEGRANULATION; IMMUNOLOGY; INFLAMMATION; KNOCKOUT MOUSE; MACROPHAGE ACTIVATION; MAST CELL; METABOLISM; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

ANIMALS; BRAIN; CELL DEGRANULATION; HYPOTHALAMUS; INFLAMMATION; MACROPHAGE ACTIVATION; MALE; MAST CELLS; MICE; MICE, KNOCKOUT; MICROGLIA; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84955247188     PISSN: 08937648     EISSN: 15591182     Source Type: Journal    
DOI: 10.1007/s12035-016-9720-x     Document Type: Article

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