GSTP1 Loss results in accumulation of oxidative DNA base damage and promotes prostate cancer cell survival following exposure to protracted oxidative stress

Prostate

Volumn 76, Issue 2, 2016, Pages 199-206

  Mian, Omar Y ^a   Khattab, Mohamed H ^a   Hedayati, Mohammad ^a   Coulter, Jonathan ^a   Abubaker Sharif, Budri ^a   Schwaninger, Julie M ^b   Veeraswamy, Ravi K ^c   Brooks, James D ^d   Hopkins, Lisa ^e   Shinohara, Debika Biswal ^a   Cornblatt, Brian ^f   Nelson, William G ^a   Yegnasubramanian, Srinivasan ^a   DeWeese, Theodore L ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^c EMORY UNIVERSITY   (United States)

^d STANFORD UNIVERSITY   (United States)

^e SAINT PETER S UNIVERSITY HOSPITAL   (United States)

^f Nuramax Laboratories   (United States)

Author keywords

cancer; GSTP1; oxidative stress; prostate

Indexed keywords

DNA BASE; GLUTATHIONE; GLUTATHIONE DISULFIDE; GLUTATHIONE TRANSFERASE P1; GSTP1 PROTEIN, HUMAN;

ARTICLE; CANCER CELL; CARCINOGENESIS; CELL SURVIVAL; CLONOGENESIS; CONTROLLED STUDY; DNA ADDUCT; DNA DAMAGE; ENZYME ACTIVITY; EPIGENETICS; GENE EXPRESSION; GENE SILENCING; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IONIZING RADIATION; LNCAP CELL LINE; MALIGNANT TRANSFORMATION; MASS FRAGMENTOGRAPHY; OXIDATIVE STRESS; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN EXPRESSION; RADIATION DOSE; DEFICIENCY; GENETICS; MALE; METABOLISM; PATHOLOGY; PHYSIOLOGY; PROSTATE TUMOR; TUMOR CELL LINE;

CELL LINE, TUMOR; CELL SURVIVAL; DNA DAMAGE; GLUTATHIONE S-TRANSFERASE PI; HUMANS; MALE; OXIDATIVE STRESS; PROSTATIC NEOPLASMS;

EID: 84955185199     PISSN: 02704137     EISSN: 10970045     Source Type: Journal    
DOI: 10.1002/pros.23111     Document Type: Article

References (28)

1. American Cancer Society, "Cancer Facts & Figures," Cancer Facts Fig., 2014.
2. Nelson WG, De Marzo AM, Isaacs WB,. Prostate cancer. N Engl J Med 2003; 349: 366-381.
3. Nelson WG, a. De Marzo M, DeWeese TL,. The molecular pathogenesis of prostate cancer: Implications for prostate cancer prevention. Urology 2001; 57: 39-45.
4. DeWeese TL, Nelson WG,. Inadequate 'caretaker' gene function and human cancer development. Methods Mol Biol 2003; 222: 249-268.
5. Huang J, Tan PH, Tan BKH, Bay BH,. GST-pi expression correlates with oxidative stress and apoptosis in breast cancer. Oncol Rep 2004; 12 (4): 921-925.
6. Townsend DM, Tew KD,. The role of glutathione-S-transferase in anti-cancer drug resistance. Oncogene 2003; 22: 7369-7375.
7. Laborde E,. Glutathione transferases as mediators of signaling pathways involved in cell proliferation and cell death. Cell Death Differ 2010; 17 (9): 1373-1380.
8. Tew KD, Manevich Y, Grek C, Xiong Y, Uys J,. The Role of Glutation S-Transferase P in signalling pathways and S-glutathionylation in cancer. Free Radic Biol Med 2012; 51 (2): 299-313.
9. Lee WH, a Morton R, Epstein JI, Brooks JD, a Campbell P, Bova GS, Hsieh WS, Isaacs WB, Nelson WG,. Cytidine methylation of regulatory sequences near the pi-class glutathione S-transferase gene accompanies human prostatic carcinogenesis. Proc Natl Acad Sci USA 1994; 91: 11733-11737.
10. Lin X, Tascilar M, Lee WH, Vles WJ, Lee BH, Veeraswamy R, Asgari K, Freije D, van Rees B, Gage WR, Bova GS, Isaacs WB, Brooks JD, DeWeese TL, a De Marzo M, Nelson WG,. GSTP1 CpG island hypermethylation is responsible for the absence of GSTP1 expression in human prostate cancer cells. Am J Pathol 2001; 159 (5): 1815-1826.
11. Yegnasubramanian S,. Hypermethylation of CpG Islands in primary and metastatic human prostate cancer. Cancer Res 2004; 64 (6): 1975-1986.
12. Nakayama M, Bennett CJ, Hicks JL, Epstein JI, a Platz E, Nelson WG, De Marzo AM,. Hypermethylation of the human glutathione S- transferase-pi gene (GSTP1) CpG island is present in a subset of proliferative inflammatory atrophy lesions but not in normal or hyperplastic epithelium of the prostate: A detailed study using laser-capture micr. Am J Pathol 2003; 163 (3): 923-933.
13. Nelson WG, Demarzo AM, Yegnasubramanian S,. The diet as a cause of human prostate cancer. Cancer Treat Res 2014; 159: 51-68.
14. Lu SC,. Regulation of glutathione synthesis. Mol Aspects Med 2009; 30 (1-2): 42-59.
15. Henderson CJ, Wolf CR, Kitteringham N, Powell H, Otto D, Park BK,. Increased resistance to acetaminophen hepatotoxicity in mice lacking glutathione S-transferase Pi. Proc Natl Acad Sci USA 2000; 97: 12741-12745.
16. Pabst MJ, Habig WH, Jakoby WB,. Glutathione S-transferase A. A novel kinetic mechanism in which the major reaction pathway depends on substrate concentration. J Biol Chem 1974; 249 (22): 7140-7147.
17. Vandeputte C, Guizon I, Genestie-Denis I, Vannier B, Lorenzon G,. A microtiter plate assay for total glutathione and glutathione disulfide contents in cultured/isolated cells: performance study of a new miniaturized protocol. Cell Biol Toxicol 1994; 10 (5-6): 415-421.
18. Dizdaroglu M,. Chemical determination of oxidative DNA damage by gas chromatography-mass spectrometry. Methods Enzymol 1994; 234: 3-16.
19. DeWeese TL, Shipman JM, a Larrier N, Buckley NM, Kidd LR, Groopman JD, Cutler RG, te Riele H, Nelson WG,. Mouse embryonic stem cells carrying one or two defective Msh2 alleles respond abnormally to oxidative stress inflicted by low-level radiation. Proc Natl Acad Sci USA 1998; 95: 11915-11920.
20. DeRisi J, Penland L, Brown PO, Bittner ML, Meltzer PS, Ray M, Chen Y, a Su Y, Trent JM,. Use of a cDNA microarray to analyse gene expression patterns in human cancer. Nat Genet 1996; 14 (4): 457-460.
21. Gerber JM, Gucwa JL, Esopi D, Gurel M, Haffner MC, Vala M, Nelson WG, Jones RJ, Yegnasubramanian S,. Genome-wide comparison of the transcriptomes of highly enriched normal and chronic myeloid leukemia stem and progenitor cell populations. Oncotarget 2013; 4 (5): 715-728.
22. DeWeese TL, Shipman JM, Buckley NM, Thomas R, Nelson WG,. Inactivation of GSTPI Genes Provides a Survival Advantage Following Oxidative DNA Damage in Human Prostate Cancer Cells. Proc Am Assoc Cancer Res 1998; 39: 466.
23. Adler V, Yin Z, Fuchs SY, Benezra M, Rosario L, Tew KD, Pincus MR, Sardana M, Henderson CJ, Wolf CR, Davis RJ, Ronai Z,. Regulation of JNK signaling by GSTp. EMBO J 1999; 18 (5): 1321-1334.
24. Pajaud J, Ribault C, Ben Mosbah I, Rauch C, Henderson C, Bellaud P, Aninat C, Loyer P, Morel F, Corlu A,. Glutathione transferases P1/P2 regulate the timing of signaling pathway activations and cell cycle progression during mouse liver regeneration. Cell Death Dis 2015; 6 (4): e1598.
25. Nelson WG, De Marzo AM, Yegnasubramanian S,. Epigenetic alterations in human prostate cancers. Endocrinology 2009; 150 (9): 3991-4002.
26. Putzi MJ, De Marzo AM,. Morphologic transitions between proliferative inflammatory atrophy and high-grade prostatic intraepithelial neoplasia. Urology 2000; 56 (5): 828-832.
27. De Marzo AM, Marchi VL, Epstein JI, Nelson WG,. Proliferative inflammatory atrophy of the prostate: implications for prostatic carcinogenesis. Am J Pathol 1999; 155 (6): 1985-1992.
28. Brooks JD, Paton VG, Vidanes G,. Potent induction of phase 2 enzymes in human prostate cells by sulforaphane. Cancer Epidemiol Biomarkers Prev 2001; 10 (9): 949-954.