The effect of dietary curcumin and capsaicin on hepatic fetuin-A expression and fat accumulation in rats fed on a high-fat diet

Archives of Physiology and Biochemistry

Volumn 122, Issue 2, 2016, Pages 94-102

  Seyithanoğlu, Muhammed ^a   Öner Iyidoğan, Yildiz ^a   Doğru Abbasoğlu, Semra ^a   Tanrikulu Küçük, Sevda ^b   Kocąk, Hikmet ^b   Beyhan Özdaş, Şule ^b   Kocąk Toker, Necla ^a  

^a ISTANBUL UNIVERSITY   (Turkey)

^b ISTANBUL BILIM UNIVERSITY   (Turkey)

Author keywords

fatty diet; Fatty liver; red pepper; turmeric; 2 Heremans Schmid glycoprotein

Indexed keywords

ADIPONECTIN; CAPSAICIN; CHOLESTEROL; CURCUMIN; FETUIN A; GLUCOSE BLOOD LEVEL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INSULIN; LEPTIN; PHOSPHOPROTEIN; TRIACYLGLYCEROL;

ADIPOSE TISSUE; ADVERSE EFFECTS; ANIMAL; BLOOD; CYTOLOGY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GLUCOSE BLOOD LEVEL; LIPID DIET; LIVER; MALE; METABOLISM; RAT; SPRAGUE DAWLEY RAT;

ADIPONECTIN; ADIPOSE TISSUE; ALPHA-2-HS-GLYCOPROTEIN; AMP-ACTIVATED PROTEIN KINASES; ANIMALS; BLOOD GLUCOSE; CAPSAICIN; CHOLESTEROL; CURCUMIN; DIET, HIGH-FAT; GENE EXPRESSION REGULATION; INSULIN; LEPTIN; LIVER; MALE; PHOSPHOPROTEINS; RATS; RATS, SPRAGUE-DAWLEY; TRIGLYCERIDES;

EID: 84955144694     PISSN: 13813455     EISSN: 17444160     Source Type: Journal    
DOI: 10.3109/13813455.2015.1120753     Document Type: Article

References (51)

1. Anand P, Kunnumakkara AB, Newman RA, Aggarwal BB. (2009). Bioavailability of curcumin: Problems and promises. Mol Pharm, 4: 807-18
2. Chalasani N, Crabb DW, Cummings OW, et al. (2003). Does leptin play a role in the pathogenesis of human nonalcoholic steatohepatitis? Am J Gastroenterol, 98: 2771-6
3. Chitturi S, Farrell G, Frost L, et al. (2002). Serum leptin in NASH correlates with hepatic steatosis but not fibrozis: A manifestation of lipotoxicity? Hepatology, 36: 403-9
4. Dasarathy S. (2014). Is the adiponectin-AMPK-mitochondrial axis involved in progression of nonalcoholic fatty liver disease? Hepatology, 60: 22-5
5. Dasgupta S, Bhattacharya S, Biswas A, et al. (2010). NFkappaBmediates lipid-induced fetuin-A expression in hepatocytes that impairs adipocyte function effecting insülin resistance. Biochem J, 429: 451-62
6. Daval M, Foufelle F, Ferré P. (2006). Functions of AMP-activated protein kinase in adipose tissue. J Physiol, 574: 55-62
7. Ejaz A, Wu D, Kwan P, Meydani M. (2009). Curcumin inhibits adipogenesis in 3T3-L1 adipocytes and angiogenesis and obesity in C57/BL mice. J Nutr, 139: 919-25
8. Folch J, Lees M, Stanley GHS. (1956). A simple method for the isolation and purification of total lipids from animal tissues. J Biol Chem, 226: 497-509
9. Ghibaudi L, Cook J, Farley C, et al. (2002). Fat intake affects adiposity, comorbidity factors, and energy metabolism of Sprague-Dawley rats. Obes Res, 10: 956-63
10. Giby VG, Ajith TA. (2014). Role of adipokines and peroxisome proliferator-activated receptors in nonalcoholic fatty liver disease. World J Hepatol, 6: 570-9
11. Gram DX, Hansen AJ, Deacon CF, et al. (2005). Sensory nerve desensitization by resiniferatoxin improves glucose tolerance and increases insulin secretion in Zucker Diabetic Fatty rats and is associated with reduced plasma activity of dipeptidyl peptidase IV. Eur J Pharmacol, 509: 211-17
12. Haukeland JW, Dahl TB, Yndestad A, et al. (2012). Fetuin A in nonalcoholic fatty liver disease in vivo and in vitro studies. Eur J Endocrinol, 166: 503-10
13. Hennige AM, Staiger H, Wicke C, et al. (2008). Fetuin-A induces cytokine expression and suppresses adiponectin production. PLoS One, 3: e1765
14. Higuchi N, Kato M, Shundo Y, et al. (2008). Liver X receptor in cooperation with SREBP-1c is a major lipid synthesis regulator in nonalcoholic fatty liver disease. Hepatol Res, 38: 1122-9
15. Ix JH, Sharma K. (2010). Mechanisms linking obesity, chronic kidney disease and fatty liver disease: The roles of fetuin-a, adiponectin and AMPK. J Am Soc Nephrol, 21: 406-12
16. Jiménez-Flores LM, López-Briones S, Maciás-Cervantes MH, et al. (2014). PPARγ, NF-B and AMPK-dependent mechanism may be involved in the beneficial effects of curcumin in the diabetic db/db mice liver. Molecules, 19: 8289-302
17. Kallwitz ER, McLachlan A, Cotler SJ. (2008). Role of peroxisome proliferators-activated receptors in the pathogenesis and treatment of nonalcoholic fatty liver disease. World J Gastroenterol, 14: 22-8
18. Kang JH, Tsuyoshi G, Le Ngoc H, et al. (2011). Dietary capsaicin attenuates metabolic dysregulation in genetically obese diabetic mice. J Med Food, 14: 310-15
19. Lavoie JM, Gauthier MS. (2006). Regulation of fat metabolism in the liver: Link to non-alcoholic hepatic steatosis and impact of physical exercise. Cell Mol Life Sci, 63: 1393-409
20. Li Q, Li L, Wang F, et al. (2013a). Dietary capsaicin prevents nonalcoholic fatty liver disease through transient receptor potential vanilloid 1-mediated peroxisome proliferator-activated receptor δ activation. Pflugers Arch-Eur J Physiol, 465: 1303-16
21. Li Y, Sun X, Yu Y. (2013b). Serum fetuin-A levels related with microalbuminuria in diet-induced obese rats. Biomed Res Int, 2013: 795103
22. Lin X, Braymer HD, Bray GA, York DA. (1998). Differential expression of insülin receptor tyrosine kinase inhibitör [fetuin] gene in a model of diet-induced obesity. Life Sci, 63: 145-53
23. Lin HZ, Yang SQ, Chuckaree C, et al. (2000). Metformin reverses fatty liver disease in obese, leptin-deficient mice. Nat Med, 6: 998-1003
24. Manjunatha H, Srinivasan K. (2006). Protective effect of curcumin, capsaicin and their combination on induced oxidation of low-density lipoprotein, iron-induced hepatotoxicity and carrageenan-induced inflammation in experimental rats. FEBS J, 273: 4528-37
25. Manjunatha H, Srinivasan K. (2007). Hypolipidemic and antioxidant effects of curcumin and capsaicin in high-fat-fed rats. Can J Physiol Pharmacol, 85: 588-96
26. Mathews ST, Chellam N, Srinivas PR, et al. (2000). Alpha2-HSG, a specific inhibitor of insülin receptor autophosphorylation, interacts with the insülin receptor. Mol Cell Endocrinol, 164: 87-98
27. Matthews DR, Hosker JP, Rudenski AS, et al. (1985). Homeostasis model assessment: Insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia, 7: 412-19
28. Moesgaard SG, Brand CL, Sturis J, et al. (2005). Sensory nerve inactivation by resiniferatoxin improves insülin sensitivity in male obese Zucker rats. Am J Physiol Endocrinol Metab, 288: 1137-45
29. Mun JM, Ok HM, Kwon O. (2014). Corn gluten hydrolysate and capsaicin have complimentary actions on body weight reduction and lipid-related genes in diet-induced obese rats. Nutr Res, 34: 458-65
30. Nelson DL, Cox MM. (2013). Lehninger principles of biochemistry. 6th ed. New York: WH Freeman and Company
31. Ochi A, Mori K, Emoto M, et al. (2014). Direct inhibitory effects of pioglitazone on hepatic fetuin-A expression. PLoS One, 9: e88704
32. Öner-Iyidoğan Y, Kocąk H, Seyidhanoğlu M, et al. (2013). Curcumin prevents liver fat accumulation and serum fetuin-A increase in rats fed a high-fat diet. J Physiol Biochem, 69: 677-86
33. Peng Y, Rideout DA, Rakita SS, et al. (2010). Does LKB1 mediate activation of hepatic AMP-protein kinase [AMPK] and sirtuin1 [SIRT1] after Roux-en-Y gastric bypass in obese rats? J Gastrointest Surg, 14: 221-8
34. Petta S, Muratore C, Craxì A. (2009). Non-alcoholic fatty liver disease pathogenesis: The present and the future. Dig Liver Dis, 41: 615-25
35. Qin X, Xie X, Fan Y, et al. (2008). Peroxisome proliferator-activated receptor-delta induces insülin-induced gene-1 and suppresses hepatic lipogenesis in obese diabetic mice. Hepatology, 48: 432-41
36. Rametta R, Ruscica M, Dongiovanni P, et al. (2014). Hepatic steatosis and PNPLA3 I148M variant are associated with serum fetuin-A independently of insülin resistance. Eur J Clin Invest, 44: 627-33
37. Ravindranath V, Chandrasekhara N. (1981). Metabolism of curcumin studies with [3H] curcumin. Toxicology, 22: 337-44
38. Satia-Abouta J, Patterson RE, Schiller RN, Kristal AR. (2002). Energy from fat is associated with obesity in US men: Result from the prostate cancer prevention trial. Prev Med, 34: 493-501
39. Sharma SK, Vij AS, Sharma S. (2013). Mechanisms and clinical uses of capsaicin. Eur J Pharm, 720: 55-62
40. Singh Ahuja H, Liu S, Crombie DL, et al. (2001). Differential effects of rexinoids and thiazolidinediones on metabolic gene expression in diabetic rodents. Mol Pharmacol, 59: 765-73
41. Smith PK, Krohn RI, Hermanson GT, et al. (1985). Measurement of protein using bicinchoninic acid. Anal Biochem, 150: 76-85
42. Song Z, Deaciuc I, Zhou Z, et al. (2007). Involvement of AMP-activated protein kinase in beneficial effects of betaine on high-sucrose diet-induced hepatic steatosis. Am J Physiol Gastrointest Liver Physiol, 293: G894-902
43. Sozio MS, Liangpunsakul S, Crabb D. (2010). The role of lipid metabolism in the pathogenesis of alcoholic and nonalcoholic hepatic steatosis. Semin Liver Dis, 30: 378-90
44. Stefan N, Hennige AM, Staiger H, et al. (2006). Alpha2-Heramans-Schmid glycoprotein/fetuin-A is associated with insülin resistance and fat accumulation in the liver in humans. Diabetes Care, 29: 853-7
45. Tang Y, Chen A. (2010). Curcumin protects hepatic stellate cells against leptin-induced activation in vitro by accumulating intracellular lipids. Endocrinology, 151: 4168-77
46. Um MY, Hwang KH, Ahn J, Ha TY. (2013). Curcumin attenuates diet-induced hepatic steatosis by activating AMP-activated protein kinase. Basic Clin Pharmacol Toxicol, 113: 152-7
47. Victor Antony Santiago J, Jayachitra J, Shenbagam M, Nalini N. (2012). Dietary d-limonene alleviates insülin resistance and oxidative stress-induced liver injury in high-fat diet and L-NAME-treated rats. Eur J Nutr, 51: 57-68
48. Viollet B, Foretz M, Guigas B, et al. (2006). Activation of AMP-activated protein kinase in the liver: A new strategy for the management of metabolic hepatic disorders. J Physiol, 5741: 41-53
49. Wang S, Moustaid-Moussa N, Chen L, et al. (2014). Novel insights of dietary polyphenols and obesity. J Nutr Biochem, 25: 1-18
50. Yoshioka M, St-Pierre S, Drapeau V, et al. (1999). Effects of red pepper on appetite and energy intake. Br J Nutr, 82: 115-23
51. Young LH. (2008). AMP-activated protein kinase conducts the ischemic stress response orchestra. Circulation, 117: 832-40