Decreased bioavailability of nitric oxide in aorta from ovariectomized senescent mice: Role of cyclooxygenase

Experimental Gerontology

Volumn 76, Issue , 2016, Pages 1-8

  Vidal Gómez, Xavier ^a,b   Novella, Susana ^a,b   Pérez Monzó, Isabel ^a,b   Garabito, Manel ^c,d   Dantas, Ana Paula ^c,d   Segarra, Gloria ^a,b   Hermenegildo, Carlos ^a,b   Medina, Pascual ^a,b  

^a UNIVERSITY OF VALENCIA   (Spain)

^b Instituto Universitario IVI INCLIVA   (Spain)

^c INSTITUT D INVESTIGACIONS BIOMÈDIQUES AUGUST PI I SUNYER IDIBAPS   (Spain)

^d Institut Clínic Del Tòrax   (Spain)

Author keywords

Aging; Estrogen; Experimental menopause; Nitric oxide; Prostanoids; Senescence accelerated mice; Vascular reactivity

Indexed keywords

ESTRADIOL; ESTROGEN; HYDROETHIDINE; INDOMETACIN; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; PROSTAGLANDIN SYNTHASE; PROSTANOID; SUPEROXIDE; THROMBOXANE A2; NITRIC OXIDE SYNTHASE; PROSTAGLANDIN SYNTHASE INHIBITOR; THROMBOXANE RECEPTOR; VASOCONSTRICTOR AGENT;

AGING; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOAVAILABILITY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; FEMALE; HEART CONTRACTION; INCUBATION TIME; MENOPAUSE; MOUSE; NONHUMAN; OVARIECTOMY; PRIORITY JOURNAL; SENESCENCE; STAINING; THORACIC AORTA; AGE; AGONISTS; ANIMAL; ANTAGONISTS AND INHIBITORS; DOSE RESPONSE; DOWN REGULATION; DRUG EFFECTS; ENZYMOLOGY; ESTROGEN THERAPY; METABOLISM; OXIDATIVE STRESS; SIGNAL TRANSDUCTION; VASOCONSTRICTION;

AGE FACTORS; AGING; ANIMALS; AORTA, THORACIC; CYCLOOXYGENASE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; ENZYME ACTIVATION; ESTRADIOL; ESTROGEN REPLACEMENT THERAPY; FEMALE; MENOPAUSE; MICE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; OVARIECTOMY; OXIDATIVE STRESS; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RECEPTORS, THROMBOXANE; SIGNAL TRANSDUCTION; SUPEROXIDES; THROMBOXANE A2; VASOCONSTRICTION; VASOCONSTRICTOR AGENTS;

EID: 84955128225     PISSN: 05315565     EISSN: 18736815     Source Type: Journal    
DOI: 10.1016/j.exger.2016.01.006     Document Type: Article

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