Effects of two organomodified clays intended to food contact materials on the genomic instability and gene expression of hepatoma cells

Food and Chemical Toxicology

Volumn 88, Issue , 2016, Pages 57-64

  Maisanaba, Sara ^a   Jordá Beneyto, María ^b   Cameán, Ana M ^a   Jos, Ángeles ^a  

^a UNIVERSITY OF SEVILLE   (Spain)

^b ITENE (Packaging Transport and Logistics Research Institute)   (Spain)

Author keywords

Cytokinesis block micronucleus cytome assay; Food contact material; Gene expression; Organomodified clays; qPCR

Indexed keywords

CHEMICAL COMPOUND; CYCLIN DEPENDENT KINASE INHIBITOR 1A; NANOCOMPOSITE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN MDM2; PROTEIN P53; ALUMINUM SILICATE; CLAY; MESSENGER RNA;

ARTICLE; BAX GENE; BCL2 GENE; CDKN1A GENE; CELL DEATH; CLAY; CONTROLLED STUDY; FOOD INDUSTRY; FOOD PACKAGING; FOOD SAFETY; GADD45A GENE; GENE; GENE EXPRESSION; GENOMIC INSTABILITY; GENOTOXICITY; HEPATOMA CELL; HUMAN; HUMAN CELL; MDM2 GENE; RISK ASSESSMENT; TP53 GENE; ANIMAL; CHEMISTRY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HEP-G2 CELL LINE; LIVER CELL CARCINOMA; LIVER TUMOR; METABOLISM; MICRONUCLEUS TEST;

ALUMINUM SILICATES; ANIMALS; CARCINOMA, HEPATOCELLULAR; FOOD PACKAGING; GENE EXPRESSION REGULATION, NEOPLASTIC; GENOMIC INSTABILITY; HEP G2 CELLS; HUMANS; LIVER NEOPLASMS; MICRONUCLEUS TESTS; RNA, MESSENGER;

EID: 84955117142     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2015.12.019     Document Type: Article

References (42)

1. Arora A., Padua G.W. Review: nanocomposites in food packaging. J. Food Sci. 2010, 75:43-49.
2. Bergaya F., Lagaly G. General introduction: clays, clay minerals, and clay science. Development in Clay Science 2013, vol. 5A:1-19. Elsevier, The Netherlands.
3. Basu A., Haldar S. The relationship between Bcl2, Bax and p53: consequences for cell cycle progression and cell death. Mol. Hum. Reprod. 1998, 4:1099-1109.
4. Bordes P., Pollet E., Avérous L. Nano- biocomposites: biodegradable polyester/nanoclay systems. Prog. Polym. Sci. 2009, 34:125-155.
5. Bressac B., Galvin K.M., Liang T.J., Isselbacher K.J., Wands J.R., Ozturk M. Abnormal structure and expression of p53 gene in human hepatocellularcarcinoma. Proc. Natl. Acad. Sci. U. S. A. 1990, 87:1973-1977.
6. Cai P., Huang Q.Y., Zhang X.W. Interactions of DNA with clay minerals and soil colloidal particles and protection against degradation by DNase. Environ. Sci. Technol. 2006, 40:2971-2976.
7. Cazzalini O., Scovassi A.I., Savio M., Stivala L.A., Prosperi E. Multiple roles of the cell cycle inhibitor p21 (CDKN1A) in the DNA damage response. Mutat. Res. Rev. Mutat. Res. 2010, 704:12-20.
8. Choudalakis G., Gotsis A.D. Permeability of polymer/clay nanocomposites: a review. Eur. Polym. J. 2009, 45:967-984.
9. European Food Safety Authority Scientific opinion on genotoxicity testingstrategies applicable to food and feed safety assessment. EFSA J. 2011, 9(9):1-69. http://dx.doi.org/10.2903/j.efsa.2011.2379www.efsa.europa.eu/efsajournal.
10. European Food Safety Draft Scientific Opinion on Recent Developments in the Risk Assessment of Chemicals in Food and Their Potential Impact N the Safety Assessment of Substances Used in Food Contact Materials 2015, 10.2903/j.efsa.20YY.NNNN.
11. Fenech M. The in vitro micronucleus technique. Mutat. Res. 2000, 455:81-95.
12. Hatzigrigoriou N.B., Papaspyrides C.D. Nanotechnology in plastic food contact materials. J. Appl. Polym. Sci. 2011, 122:3720-3739.
13. Houtman J., Maisanaba S., Puerto M., Gutiérrez-Praena D., Jordá M., Aucejo S., Jos A. Toxicity assessment of organomodified clays used in food contact materials on human target cell lines. Appl. Clay Sci. 2014, 90:150-158.
14. Hsu S.H., Wang M.C., Lin J.J. Biocompatibility and antimicrobial evaluation of montmorillonite/chitosan nanocomposites. Appl. Clay Sci. 2012, 56:53-62.
15. Iwakuma T., Lozano G. MDM2, an introduction. Mol. Cancer Res. 2003, 1:993-1000.
16. Jorda-Beneyto M., Ortuño N., Devis A., Aucejo A., Puerto M., Gutiérrez-Praena D., Houtman H., Pichardo S., Maisanaba S., Jos A. Use of nanoclay platelets in food packaging materials: technical and cytotoxicity approach. Food Addit. Contam. A 2014, 31:354-363.
17. Knasmuller S., Mersch-Sundermann V., Kevekordes S., Darroudi F., Huber W.W., Hoelzl C., Bichler J., Majer B.J. Use of human-derived liver cell lines for the detection of environmental and dietary genotoxicants; current state of knowledge. Toxicology 2004, 198:315-328.
18. Kumari B., Banerjee S.S., Singh V., Das P., Bhowmick A.K. Processing of abasic site damaged lesions by APE1 enzyme on DNA adsorbed over normal and organomodified clay. Chemosphere 2014, 112:503-510.
19. Lee S.R., Park H.M., Lim H.T., Kang K.Y., Li L., Cho W.J., Ha C.S. Microstructure, tensile properties, and biodegradability of aliphatic polyester/clay nanocomposites. Polymer 2002, 43:2495-2500.
20. Leszczynska A., Njuguna J., Pielichowski K., Banerjee J.R. Thermal stability of polymer/montmorillonite nanocomposites. Part I: factors influencing thermal stability and mechanisms of thermal stability improvement. Thermo. Acta 2007, 453:75-96.
21. Maisanaba S., Puerto M., Pichardo S., Jordá M., Moreno F.J., Aucejo S., Jos A. In vitro toxicological assessment of clays for their use in food packaging applications. Food Chem. Toxicol. 2013, 57:266-275.
22. Maisanaba S., Gutiérrez-Praena D., Pichardo S., Moreno F.J., Jordá M., Cameán A.M., Aucejo S., Jos A. Toxic effects of a modified montmorillonite clay on the human intestinal cell line Caco-2. J. Appl. Toxicol. 2014, 34:714-725.
23. Maisanaba S., Prieto A.I., Pichardo S., Jordá-Beneyto M., Aucejo S., Jos A. Cytotoxicity and mutagenicity assessment of organomodified clays potentially used in food packaging. Toxicol. In Vitro 2015, 29:1222-1230.
24. Maisanaba S., Pichardo S., Puerto M., Gutiérrez-Praena D., Caméan A.M., Jos A. Toxicological evaluation of clay minerals and derived nanocomposites. A review. Environ. Res. 2015, 138:233-254.
25. Maisanaba S., Hercog K., Filipic M., Jos A., Zegura B. Genotoxic potential of montmorillonite clay mineral and alteration in the expression of genes involved in toxicity mechanisms in the human hepatoma cell line HepG2. J. Hazard Mater. 2015, 10.1016/j.jhazmat.2015.10.018.
26. Maisanaba S., Zegura B., Jordá-Beneyto M., Jos A. The impact of novel clays destined to food packaging on the genomic instability of human hepatoma cells. Toxicol. Lett. 2015, 238S:S79.
27. Maisanaba S., Hercog K., Zegura B., Filipic M., Jos A. The influence of clays with an application in the food industry on the mRNA expression of selected genes in human hepatoma cells. Toxicol. Lett. 2015, 238S:S79.
28. Mendoza-Rodríguez C.A., Cerbón M.A. Tumor suppressor gene p53: mechanisms of action in cell proliferation and death. Rev. Invest. Clin. 2001, 53:266-273.
29. OECD Guideline for the Testing of Chemicals 487: in Vitro Mammalian Cell Micronucleus Test 2014, 1-26.
30. Rhim J.-W., Park H.-M., Ha C.-S. Bio-nanocomposites for food packaging applications. Prog. Polym. Sci. 2013, 38:1629-1652.
31. Sharma A.K., Schmidt B., Frandsen H., Jacobsen N.R., Larsen E.H., Binderup M.L. Genotoxicity of unmodified and organo-modified montmorillonite. Mutat. Res. 2010, 700:18-25.
32. Sinha Ray S., Okamoto M. Polymer/layered silicate nanocomposites: a review from preparation to processing. Prog. Polym. Sci. 2003, 28:1539-1641.
33. Sinha Ray S., Bousima M. Biodegradable polymers and their layered silicate nanocomposites: in greening the 21st century materials world. Prog. Mater. Sci. 2005, 50:962-1079.
34. Straser A., Filipic M., Zegura B. Cylindrospermopsin induced transcriptional responses in human hepatoma HepG2 cells. Toxicol. In Vitro 2013, 27:1809-1819.
35. Straser A., Filipic M., Zegura B. Genotoxic effects of the cyanobacterialhepatotoxin cylindrospermopsin in the HepG2 cell line. Arch. Toxicol. 2011, 85:1617-1626.
36. Swadling J.B., Coveney P.V., Greenwell H.C. Clay minerals mediate folding and regioselective interactions of RNA: a large-scale atomistic simulation study. J. Am. Chem. Soc. 2010, 132:13750-13764.
37. Theng B.K.G. The clay minerals. Dev. Clay Sci. 2012, 4:3-45.
38. Toshiyuki M., Reed J. Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell 1995, 80:293-299.
39. Uyama H., Kuwabara M., Tsujimoto T., Nakano M., Usuki A., Kobayashi S. Green nanocomposite from renewable resources: plant oil-clay hybrid materials. Chem. Mater. 2003, 15:2492-2494.
40. van Delft J.H.M., van Agen E., van Breda S.G.J., Herwijnen M.H., Staal Y.C.M., Kleinjans J.C.S. Discrimination of genotoxic from non-genotoxic carcinogens by gene expression profiling. Carcinogenesis 2004, 25:1265-1276.
41. Wang X.W., Zhan Q.M., Coursen J.D., Khan M.A., Kontny H.U., Yu L.J., Hollander M.C., O'Connor P.M., Fornace A.J., Harris C.C. GADD45 induction of a G(2)/M cell cycle checkpoint. Proc. Natl. Acad. Sci. U. S. A. 1999, 96:3706-3711.
42. Zhu H., Njuguna J. Nanolayered silicates/clay minerals: uses and effects on health. Health and Environmental Safety of Nanomaterials, Polymer Nanocomposites and Other Materials Containing Nanoparticles 2014, 133-145. Woodhead Publishing, Elsevier, Amsterdam. J. Njuguna, K. Pielichowski, H. Zhu (Eds.).