PMCA2 regulates HER2 protein kinase localization and signaling and promotes HER2-mediated breast cancer

Proceedings of the National Academy of Sciences of the United States of America

Volumn 113, Issue 3, 2016, Pages E282-E290

  Jeong, Jaekwang ^a   Van Houten, Joshua N ^a   Dann, Pamela ^a   Kim, Wonnam ^a   Sullivan, Catherine ^a   Yu, Herbert ^b   Liotta, Lance ^c   Espina, Virginia ^c   Stern, David F ^a   Friedman, Peter A ^d   Wysolmerski, John J ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF HAWAII CANCER CENTER   (United States)

^c GEORGE MASON UNIVERSITY   (United States)

^d UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; CALCIUM; EPIDERMAL GROWTH FACTOR RECEPTOR 2; HEAT SHOCK PROTEIN 90; MESSENGER RNA; PLASMA MEMBRANE CALCIUM ATPASE2; PLASMA MEMBRANE CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; UNCLASSIFIED DRUG; ATP2B2 PROTEIN, HUMAN; ATP2B2 PROTEIN, MOUSE; ERBB2 PROTEIN, HUMAN; FORKHEAD TRANSCRIPTION FACTOR; FOXO1 PROTEIN, HUMAN; PROTEIN BINDING; TRANSCRIPTION FACTOR FKHR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREAST CANCER; CALCIUM CELL LEVEL; CANCER GROWTH; CANCER MORTALITY; CONTROLLED STUDY; INTERNALIZATION; INTRACELLULAR SIGNALING; MOLECULAR INTERACTION; MOUSE; MOUSE MAMMARY TUMOR VIRUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; ANIMAL; BREAST TUMOR; CARCINOGENESIS; CELL MEMBRANE; CELL PROLIFERATION; CELL SURVIVAL; DRUG EFFECTS; ENDOCYTOSIS; EXPERIMENTAL MAMMARY NEOPLASM; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; GENE SILENCING; HUMAN; IMMUNOBLOTTING; INTRACELLULAR SPACE; METABOLISM; PATHOLOGY; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; SURVIVAL ANALYSIS; TUMOR CELL LINE;

ANIMALS; BREAST NEOPLASMS; CALCIUM; CARCINOGENESIS; CELL LINE, TUMOR; CELL MEMBRANE; CELL PROLIFERATION; CELL SURVIVAL; ENDOCYTOSIS; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; FORKHEAD BOX PROTEIN O1; FORKHEAD TRANSCRIPTION FACTORS; GENE KNOCKDOWN TECHNIQUES; HSP90 HEAT-SHOCK PROTEINS; HUMANS; IMMUNOBLOTTING; INTRACELLULAR SPACE; MAMMARY NEOPLASMS, ANIMAL; MICE; PLASMA MEMBRANE CALCIUM-TRANSPORTING ATPASES; PROTEIN BINDING; PROTEIN TRANSPORT; RECEPTOR, ERBB-2; SIGNAL TRANSDUCTION; SURVIVAL ANALYSIS;

EID: 84955060050     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1516138113     Document Type: Article

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