Exosomes from HIV-1-infected cells stimulate production of pro-inflammatory cytokines through trans-activating response (TAR) RNA

Journal of Biological Chemistry

Volumn 291, Issue 3, 2016, Pages 1251-1266

  Sampey, Gavin C ^a   Saifuddin, Mohammed ^a   Schwab, Angela ^a   Barclay, Robert ^a   Punya, Shreya ^a   Chung, Myung Chul ^a   Hakami, Ramin M ^a   Zadeh, Mohammad Asad ^a   Lepene, Benjamin ^b   Klase, Zachary A ^c   El Hage, Nazira ^d   Young, Mary ^e   Iordanskiy, Sergey ^a   Kashanchi, Fatah ^a  

^a GEORGE MASON UNIVERSITY   (United States)

^b CERES NANOSCIENCES INC   (United States)

^c UNIVERSITY OF THE SCIENCES   (United States)

^d FLORIDA INTERNATIONAL UNIVERSITY   (United States)

^e GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINS; CELLS; CHEMICAL ACTIVATION; CYTOLOGY; DISEASE CONTROL; DISEASES; GENE EXPRESSION; GENES; MOLECULES; PATIENT TREATMENT; POLYMERASE CHAIN REACTION; RNA; VIRUSES;

CARDIO-VASCULAR DISEASE; CYTOKINE EXPRESSION; DOMINANT NEGATIVE; HIGHLY ACTIVE ANTI-RETROVIRAL THERAPIES; INFECTED PATIENTS; METABOLIC DISORDERS; POSSIBLE MECHANISMS; PRO-INFLAMMATORY CYTOKINES;

TAR;

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; LYMPHOTOXIN; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8; VIRUS RNA; ACTIVATING TRANSCRIPTION FACTOR; CYTOKINE; IL6 PROTEIN, HUMAN; MICRORNA; PROTEIN KINASE R; TLR3 PROTEIN, HUMAN; TOLL LIKE RECEPTOR 3;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL STIMULATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; EXOSOME; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; MACROPHAGE; MOUSE; NONHUMAN; PRIMARY CELL CULTURE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; ACTIVE TRANSPORT; ANIMAL; ANTAGONISTS AND INHIBITORS; BLOOD; CELL CULTURE; CELL LINE; GENETICS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOLOGY; LEUKOCYTE; METABOLISM; NONOBESE DIABETIC MOUSE; SECRETION (PROCESS); TRANSFORMED CELL LINE; TRANSGENIC MOUSE; VIROLOGY; VIRUS CELL TRANSFORMATION;

ACTIVATING TRANSCRIPTION FACTORS; ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; CELL LINE; CELL LINE, TRANSFORMED; CELL TRANSFORMATION, VIRAL; CELLS, CULTURED; CYTOKINES; EIF-2 KINASE; EXOSOMES; HIV INFECTIONS; HIV-1; HUMANS; INTERLEUKIN-6; LEUKOCYTES; LYMPHOTOXIN-ALPHA; MICE, INBRED NOD; MICE, TRANSGENIC; MICRORNAS; TOLL-LIKE RECEPTOR 3;

EID: 84954540868     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.662171     Document Type: Article

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