Accelerated cardiac remodeling in desmoplakin transgenic mice in response to endurance exercise is associated with perturbed wnt/β-catenin signaling

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 310, Issue 2, 2016, Pages H174-H187

  Martherus, Ruben ^a   Jain, Rahul ^b   Takagi, Ken ^a,c   Mendsaikhan, Uzmee ^a   Turdi, Subat ^a   Osinska, Hanna ^a   James, Jeanne F ^a   Kramer, Kristen ^a   Purevjav, Enkhsaikhan ^a   Towbin, Jeffrey A ^a  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^b INDIANA UNIVERSITY   (United States)

^c JIKEI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Glycogen synthase kinase 3 ; Protein kinase B

Indexed keywords

BETA CATENIN; CONNEXIN 43; DESMOPLAKIN; GLYCOGEN SYNTHASE KINASE 3BETA; PLAKOGLOBIN; PROTEIN KINASE B; RNA; WNT PROTEIN; CTNNB1 PROTEIN, MOUSE; DSP PROTEIN, MOUSE; GLYCOGEN SYNTHASE KINASE 3;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE COURSE; ECHOCARDIOGRAPHY; ELECTROCARDIOGRAPHY; ENDURANCE TRAINING; HEART FUNCTION; HEART RIGHT VENTRICLE DYSPLASIA; HEART VENTRICLE REMODELING; HISTOLOGY; IMMUNOHISTOCHEMISTRY; MICROTUBULE; MOUSE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE; UPREGULATION; ANIMAL; ARRHYTHMOGENIC RIGHT VENTRICULAR DYSPLASIA; BIOSYNTHESIS; C57BL MOUSE; CARDIAC MUSCLE; DIAGNOSTIC IMAGING; ECHOGRAPHY; ENDURANCE; GENETICS; HEART FUNCTION TEST; HUMAN; MUTATION; PATHOLOGY; PHYSIOLOGY; RUNNING; SEDENTARY LIFESTYLE;

ANIMALS; ARRHYTHMOGENIC RIGHT VENTRICULAR DYSPLASIA; BETA CATENIN; DESMOPLAKINS; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; HEART FUNCTION TESTS; HUMANS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MUTATION; MYOCARDIUM; PHYSICAL CONDITIONING, ANIMAL; PHYSICAL ENDURANCE; RUNNING; SEDENTARY LIFESTYLE; ULTRASONOGRAPHY;

EID: 84954536093     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00295.2015     Document Type: Article

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