Neutrophilic oxidative stress mediates organic dust-induced pulmonary inflammation and airway hyperresponsiveness

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 310, Issue 2, 2016, Pages L155-L165

  McGovern, Toby K ^a,b   Chen, Michael ^b   Allard, Benoit ^b   Larsson, Kjell ^a   Martin, James G ^b   Adner, Mikael ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

Anti Ly6G; Antioxidants; Neutrophilia; Organic dust; Oxidative stress

Indexed keywords

ANTIBODY; CATALASE; COPPER ZINC SUPEROXIDE DISMUTASE; CYTOKINE; DIMETHYLTHIOUREA; GLUTATHIONE PEROXIDASE 2; HEME OXYGENASE 1; LY6G ANTIBODY; METHACHOLINE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 1; THIOREDOXIN 1; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; METHACHOLINE CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; BRONCHOALVEOLAR LAVAGE FLUID; CONTROLLED STUDY; DISEASE EXACERBATION; GENE EXPRESSION; HISTOPATHOLOGY; KERATINOCYTE; LUNG PARENCHYMA; MALE; MOUSE; NEUTROPHIL; NEUTROPHILIA; NONHUMAN; ORGANIC DUST; OXIDATIVE STRESS; PRIORITY JOURNAL; RESPIRATORY TRACT ALLERGY; RESPIRATORY TRACT INFLAMMATION; ANIMAL; BAGG ALBINO MOUSE; BRONCHUS HYPERREACTIVITY; CYTOLOGY; DRUG EFFECTS; IMMUNOLOGY; METABOLISM; NEUTROPHIL CHEMOTAXIS; PNEUMONIA;

ANIMALS; BRONCHIAL HYPERREACTIVITY; CYTOKINES; MALE; METHACHOLINE CHLORIDE; MICE, INBRED BALB C; NEUTROPHIL INFILTRATION; NEUTROPHILS; OXIDATIVE STRESS; PNEUMONIA; RESPIRATORY HYPERSENSITIVITY;

EID: 84954509510     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00172.2015     Document Type: Article

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