Swine dust induces cytokine secretion from human epithelial cells and alveolar macrophages

Clinical and Experimental Immunology

Volumn 115, Issue 1, 1999, Pages 6-12

  Wang, Z ^a   Malmberg, P ^a   Ek, A ^a   Larsson, K ^a   Palmberg, Lena ^a  

^a NATIONAL INSTITUTE FOR WORKING LIFE   (Sweden)

Author keywords

Alveolar macrophages; Epithelial cells; IL 6 tumour necrosis factor alpha; Lipopolysaccharide; Organic dust (swine dust)

Indexed keywords

CYTOKINE; INTERLEUKIN 1BETA; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; BRONCHUS MUCOSA; CONTROLLED STUDY; CYTOKINE RELEASE; DUST; ENZYME LINKED IMMUNOSORBENT ASSAY; EPITHELIUM CELL; HUMAN; HUMAN CELL; LUNG ALVEOLUS MACROPHAGE; LUNG LAVAGE; PRIORITY JOURNAL; SWINE;

ANIMALS; CELL LINE; CELL-FREE SYSTEM; CULTURE MEDIA; CYTOKINES; DUST; ENDOTOXINS; EPITHELIAL CELLS; HOUSING, ANIMAL; HUMANS; INTERLEUKIN-1; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MACROPHAGES, ALVEOLAR; RECOMBINANT PROTEINS; SWINE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0032939059     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.1999.00776.x     Document Type: Article

References (22)

1. 1 Larsson K, Eklund A, Hansson L-O, Isaksson B-M, Malmberg P. Swine dust causes intense airways inflammation in healthy subjects. Am J Respir Crit Care Med 1994; 150:973-7.
2. 2 Müller-Suur C, Larsson K, Malmberg P, Larsson PH. Increased number of activated lymphocytes in human lung following swine dust inhalation. Eur Respir J 1997; 10:376-80.
3. 3 Wang Z, Larsson K, Palmberg L, Malmberg P, Larsson P, Larsson L. Inhalation of swine dust induces cytokine release in the upper and lower airways. Eur Respir J 1997; 10:381-7.
4. 4 Wang Z, Malmberg P, Larsson P, Larsson B-M, Larsson K. Time course of interleukin-6 and tumor necrosis factor-α increase in serum following inhalation of swine dust. Am J Respir Crit Care Med 1996; 153:147-52.
5. 5 Zhiping W, Malmberg P, Larsson B-M, Larsson K, Larsson L, Saraf A. Exposure to bacteria in swine-house dust and acute inflammatory reactions in humans. Am J Respir Crit Care Med 1996; 154:1261-6.
6. 6 Sandström T, Bjermer L, Rylander R. Lipopolysaccharide (LPS) inhalation in healthy subjects increases neutrophils, lymphocytes and fibronectin levels in bronchoalveolar lavage fluid. Eur Respir J 1992; 5:992-6.
7. 7 Palmberg L, Larsson B-M, Malmberg P, Larsson K. Induction of IL-8 production in human alveolar macrophages and human bronchial epithelial cells in vitro by swine dust. Thorax 1998; 53:260-4.
8. 8 Huag ZB, Eden E. Effect of bronchoalveolar lavage fluid from patients with sarcoidosis or AIDS on interleukin 1β release from alveolar macrophages. Chest 1990; 98:576-80.
9. 9 Larsson B-M, Palmberg L, Larsson K, Malmberg P. Gram positive bacteria induce IL-8 production in epithelial cell line A549. Eur Respir J 1995; 8:225s.
10. 10 Crook B, Robertson JF, Travers-Glass SA, Botheroyd E, Lacey J, Topping MD. Airborne dust, ammonia, microorganisms and antigens in pig confinement houses and respiratory health of exposed farm workers. Am Ind Hyg Assoc J 1991; 52:271-9.
11. 11 Burrel R. Immunomodulation by bacterial endotoxin. Crit Rev Microbiol 1990; 17:189-208.
12. 12 Andersson J, Nagy S, Björk L, Abrams J, Holm S, Andersson U. Bacterial toxin-induced cytokine production studied at the single-cell level. Immunol Rev 1992; 127:69-96.
13. 13 Hedges S, Svensson M, Svanborg C. Interleukin-6 response of epithelial cell lines to bacterial stimulation in vitro. Infect Immun 1992; 60:1295-301.
14. 14 Loppnow H, Libby P, Freudenberg M, Krauss JH, Weckesser J, Mayer H. Cytokine induction by lipopolysaccharide (LPS) corresponds to lethal toxicity and is inhibited by nontoxic Rhodobacter capsulatus LPS. Infect Immun 1990; 58:3743-50.
15. 15 Jirik FR, Podor TJ, Hirano T, Kishimoto T, Loskutoff DJ, Carson DA, Lotz M. Bacterial lipopolysaccharide and inflammatory mediators augment IL-6 secretion by human endothelial cells. J Immunol 1989; 142:144-7.
16. 16 de Man P, van Kooten C, Aarden L, Engberg I, Linder H, Svanborg Edén C. Interleukin-6 induced at mucosal surfaces by Gram-negative bacterial infection. Infect Immun 1989; 57:3383-8.
17. 17 Xing Z, Jordana M, Kirpaleni H, Dirscoll KE, Schall TJ, Gauldie J. Cytokine expression by neutrophils and macrophages in vivo: endotoxin induces tumor necrosis factor-alpha, macrophage inflammatory protein-2, interleukin-1 beta, and interleukin-6 but not RANTES or transforming growth factor-beta 1 mRNA expression in acute lung inflammation. Am J Respir Cell Mol Biol 1994; 10:148-53.
18. 18 Frey EA, Miller DS, Jahr TG, Sundan A, Bazil V, Espevik T, Finlay BB, Wright SD. Soluble CD14 participates in the response of cells to lipopolysaccharide. J Exp Med 1990; 176:1665-71.
19. 19 Spriggs DR, Imamura K, Rodriguez C, Sariban E, Kufe DW. Tumor necrosis factor expression in human epithelial tumor cell lines. J Clin Invest 1988; 81:455-69.
20. 20 Khair OA, Devalia JL, Abdelaziz MM, Sapsford RJ, Tarraf H, Davies RJ. Effect of Haemophilus influenzae endotoxin on the synthesis of IL-6, IL-8, TNF-α and expression of ICAM-1 in cultured human bronchial epithelial cells. Eur Respir J 1994; 7:2109-16.
21. 21 Devalia JL, Campbell AM, Sapsford RJ, Rusznak C, Quint D, Godard P, Bousquet J, Davies RJ. Effect of nitrogen dioxide on synthesis of inflammatory cytokines expressed by human bronchial epithelial cell in vitro. Am J Respir Cell Mol Biol 1993; 9:271-8.
22. 22 Barnes PJ. Airway epithelial receptors. Eur Respir Rev 1994; 4:371-9.