Methionine and S-adenosylmethionine levels are critical regulators of PP2A activity modulating lipophagy during steatosis

Journal of Hepatology

Volumn 64, Issue 2, 2016, Pages 409-418

  Zubiete Franco, Imanol ^a   García Rodríguez, Juan Luis ^a   Martínez Uña, Maite ^b   Martínez Lopez, Nuria ^a   Woodhoo, Ashwin ^a,d   Juan, Virginia Gutiérrez De ^a   Beraza, Naiara ^a,d   Lage Medina, Sergio ^c   Andrade, Fernando ^c   Fernandez, Marta Llarena ^c   Aldámiz Echevarría, Luis ^c   Fernández Ramos, David ^a   Falcon Perez, Juan Manuel ^a,d   Lopitz Otsoa, Fernando ^a   Fernandez Tussy, Pablo ^a   Barbier Torres, Lucía ^a   Luka, Zigmund ^f   Wagner, Conrad ^f   García Monzón, Carmelo ^e   Lu, Shelly C ^g,h   Aspichueta, Patricia ^b   Mato, José María ^a   Martínez Chantar, María Luz ^a,b   Varela Rey, Marta ^a   more..

^a INSTITUTO DE SALUD CARLOS III   (Spain)

^b UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

^c HOSPITAL DE CRUCES   (Spain)

^d BASQUE FOUNDATION FOR SCIENCE   (Spain)

^e HOSPITAL UNIVERSITARIO SANTA CRISTINA   (Spain)

^f VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g CEDARS SINAI MEDICAL CENTER   (United States)

^h UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Autophagy; Gnmt; Liver; Methionine; SAMe; Steatosis

Indexed keywords

AMINO ACID; AMINOTRANSFERASE; AMMONIUM CHLORIDE; FAT DROPLET; GLYCINE METHYLTRANSFERASE; GLYCOGEN; GROWTH FACTOR; INSULIN; LEUPEPTIN; MAMMALIAN TARGET OF RAPAMYCIN; METHIONINE; OKADAIC ACID; OLEIC ACID; PHOSPHOPROTEIN PHOSPHATASE 2A; S ADENOSYLMETHIONINE; VERY LOW DENSITY LIPOPROTEIN; PHOSPHOPROTEIN PHOSPHATASE 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CELL CULTURE; CLINICAL ASSESSMENT; COMPARATIVE STUDY; CONTROLLED STUDY; FATTY LIVER; GENE EXPRESSION; HUMAN; HUMAN CELL; LIPID STORAGE; LIPOLYSIS; LIPOPHAGOCYTOSIS; LIVER CELL; LYSOSOME; MAJOR CLINICAL STUDY; MALE; MOUSE; NONALCOHOLIC FATTY LIVER; NONHUMAN; NUTRITIONAL DEFICIENCY; PRIORITY JOURNAL; PROTEIN METHYLATION; ANIMAL; BLOOD; CELL CULTURE TECHNIQUE; DISEASE MODEL; METABOLISM; METHYLATION; PATHOLOGY; PHYSIOLOGY;

ANIMALS; AUTOPHAGY; CELL CULTURE TECHNIQUES; DISEASE MODELS, ANIMAL; FATTY LIVER; HEPATOCYTES; HUMANS; METHIONINE; METHYLATION; MICE; PROTEIN PHOSPHATASE 2; S-ADENOSYLMETHIONINE;

EID: 84954402163     PISSN: 01688278     EISSN: 16000641     Source Type: Journal    
DOI: 10.1016/j.jhep.2015.08.037     Document Type: Article

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