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Volumn 13, Issue 1, 2016, Pages 555-559

Telmisartan prevents proliferation and promotes apoptosis of human ovarian cancer cells through upregulating PPARγ and downregulating MMP-9 expression

Author keywords

Matrix metalloproteinase 9; Ovarian cancer; Peroxisome proliferator activated receptor ; Telmisartan

Indexed keywords

CASPASE 3; FLUORESCEIN ISOTHIOCYANATE; GELATINASE B; LIPOCORTIN 5; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROPIDIUM IODIDE; SMALL INTERFERING RNA; TELMISARTAN; BENZIMIDAZOLE DERIVATIVE; BENZOIC ACID DERIVATIVE;

EID: 84954306776     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2015.4512     Document Type: Article
Times cited : (17)

References (34)
  • 1
    • 33646568784 scopus 로고    scopus 로고
    • Patterns of cancer incidence, mortality and prevalence across five continents: Defining priorities to reduce cancer disparities in different geographic regions of the world
    • Kamangar F, Dores GM and Anderson WF: Patterns of cancer incidence, mortality and prevalence across five continents: Defining priorities to reduce cancer disparities in different geographic regions of the world. J Clin Oncol 24: 2137-2150, 2006.
    • (2006) J Clin Oncol , vol.24 , pp. 2137-2150
    • Kamangar, F.1    Dores, G.M.2    Anderson, W.F.3
  • 2
    • 25844489137 scopus 로고    scopus 로고
    • Factors affecting participation in a breast cancer risk reduction telephone survey among women from four racial/ethnic groups
    • Des Jarlais G, Kaplan CP, Haas JS, Gregorich SE, Perez-Stable EJ and Kerlikowske K: Factors affecting participation in a breast cancer risk reduction telephone survey among women from four racial/ethnic groups. Prev Med 41: 720-727, 2005.
    • (2005) Prev Med , vol.41 , pp. 720-727
    • Des Jarlais, G.1    Kaplan, C.P.2    Haas, J.S.3    Gregorich, S.E.4    Perez-Stable, E.J.5    Kerlikowske, K.6
  • 4
    • 36549043459 scopus 로고    scopus 로고
    • Ovarian cancer hormonal and environmental risk effect
    • viii
    • Vo C and Carney ME: Ovarian cancer hormonal and environmental risk effect. Obstet Gynecol Clin North Am 34: 687-700, viii, 2007.
    • (2007) Obstet Gynecol Clin North Am , vol.34 , pp. 687-700
    • Vo, C.1    Carney, M.E.2
  • 5
    • 33845904633 scopus 로고    scopus 로고
    • Expression of peroxisome proliferators-activated receptor-gamma and cyclooxygenase-2 in Helicobacter pylori infection-associated diseases and significance thereof
    • In Chinese
    • Xie Y, Zhu J, Zhou XJ, Chen J, Lu NH and Wang CW: Expression of peroxisome proliferators-activated receptor-gamma and cyclooxygenase-2 in Helicobacter pylori infection-associated diseases and significance thereof. Zhonghua Yi Xue Za Zhi 86: 2683-2689, 2006 (In Chinese).
    • (2006) Zhonghua Yi Xue Za Zhi , vol.86 , pp. 2683-2689
    • Xie, Y.1    Zhu, J.2    Zhou, X.J.3    Chen, J.4    Lu, N.H.5    Wang, C.W.6
  • 7
    • 0033999211 scopus 로고    scopus 로고
    • Peroxisome proliferator activated receptor-gamma (PPAR-gamma) mediates the action of gamma linolenic acid in breast cancer cells
    • Jiang WG, Redfern A, Bryce RP and Mansel RE: Peroxisome proliferator activated receptor-gamma (PPAR-gamma) mediates the action of gamma linolenic acid in breast cancer cells. Prostaglandins Leukot Essent Fatty Acids 62: 119-127, 2000.
    • (2000) Prostaglandins Leukot Essent Fatty Acids , vol.62 , pp. 119-127
    • Jiang, W.G.1    Redfern, A.2    Bryce, R.P.3    Mansel, R.E.4
  • 8
    • 0035892366 scopus 로고    scopus 로고
    • Molecular genetic analysis of the von Hippel-Lindau and human peroxisome proliferator-activated receptor gamma tumor-suppressor genes in adenocarcinomas of the gastroesophageal junction
    • Wijnhoven BP, Lindstedt EW, Abbou M, Ijzendoorn Y, de Krijger RR, Tilanus HW and Dinjens WN; Rotterdam Esophageal Tumor Study Group: Molecular genetic analysis of the von Hippel-Lindau and human peroxisome proliferator-activated receptor gamma tumor-suppressor genes in adenocarcinomas of the gastroesophageal junction. Int J Cancer 94: 891-895, 2001.
    • (2001) Int J Cancer , vol.94 , pp. 891-895
    • Rotterdam Esophageal Tumor Study Group1    Wijnhoven, B.P.2    Lindstedt, E.W.3    Abbou, M.4    Ijzendoorn, Y.5    De Krijger, R.R.6    Tilanus, H.W.7    Dinjens, W.N.8
  • 9
    • 0034652462 scopus 로고    scopus 로고
    • Induction of differentiation and apoptosis by ligands of peroxisome proliferator-activated receptor gamma in non-small cell lung cancer
    • Chang TH and Szabo E: Induction of differentiation and apoptosis by ligands of peroxisome proliferator-activated receptor gamma in non-small cell lung cancer. Cancer Res 60: 1129-1138, 2000.
    • (2000) Cancer Res , vol.60 , pp. 1129-1138
    • Chang, T.H.1    Szabo, E.2
  • 11
    • 84895860919 scopus 로고    scopus 로고
    • Improvement of metabolic syndrome by irbesartan via the PPARα/HGF pathway in apolipoprotein e knockout mice
    • Chatterjee A, Kusunoki H, Taniyama Y, Rakugi H and Morishita R: Improvement of metabolic syndrome by irbesartan via the PPARα/HGF pathway in apolipoprotein E knockout mice. Biomed Rep 1: 65-70, 2013
    • (2013) Biomed Rep , vol.1 , pp. 65-70
    • Chatterjee, A.1    Kusunoki, H.2    Taniyama, Y.3    Rakugi, H.4    Morishita, R.5
  • 13
    • 14044278906 scopus 로고    scopus 로고
    • Circulating activators of peroxisome proliferator-activated receptors are reduced in preeclamptic pregnancy
    • Waite LL, Louie RE and Taylor RN: Circulating activators of peroxisome proliferator-activated receptors are reduced in preeclamptic pregnancy. J Clin Endocrinol Metab 90: 620-626, 2005.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 620-626
    • Waite, L.L.1    Louie, R.E.2    Taylor, R.N.3
  • 14
    • 23244448038 scopus 로고    scopus 로고
    • Peroxisome proliferator activated receptor-gamma ligands induced cell growth inhibition and its influence on matrix metalloproteinase activity in human myeloid leukemia cells
    • Liu J, Lu H, Huang R, Lin D, Wu X, Lin Q, Wu X, Zheng J, Pan X, Peng J, et al: Peroxisome proliferator activated receptor-gamma ligands induced cell growth inhibition and its influence on matrix metalloproteinase activity in human myeloid leukemia cells. Cancer Chemother Pharmacol 56: 400-408, 2005.
    • (2005) Cancer Chemother Pharmacol , vol.56 , pp. 400-408
    • Liu, J.1    Lu, H.2    Huang, R.3    Lin, D.4    Wu, X.5    Lin, Q.6    Wu, X.7    Zheng, J.8    Pan, X.9    Peng, J.10
  • 15
    • 84861159160 scopus 로고    scopus 로고
    • Telmisartan in the management of diabetic nephropathy: A contemporary view
    • Balakumar P, Bishnoi HK and Mahadevan N: Telmisartan in the management of diabetic nephropathy: A contemporary view. Curr Diabetes Rev 8: 183-190, 2012.
    • (2012) Curr Diabetes Rev , vol.8 , pp. 183-190
    • Balakumar, P.1    Bishnoi, H.K.2    Mahadevan, N.3
  • 17
    • 84871727291 scopus 로고    scopus 로고
    • Telmisartan or valsartan alone or in combination with hydrochlorothiazide: A review
    • Lacourciere Y: Telmisartan or valsartan alone or in combination with hydrochlorothiazide: A review. Clin Exp Hypertens 35: 50-60, 2013.
    • (2013) Clin Exp Hypertens , vol.35 , pp. 50-60
    • Lacourciere, Y.1
  • 18
    • 79957610506 scopus 로고    scopus 로고
    • Telmisartan, a unique ARB, improves left ventricular remodeling of infarcted heart by activating PPAR gamma
    • Maejima Y, Okada H, Haraguchi G, Onai Y, Kosuge H, Suzuki J and Isobe M: Telmisartan, a unique ARB, improves left ventricular remodeling of infarcted heart by activating PPAR gamma. Lab Invest 91: 932-944, 2011.
    • (2011) Lab Invest , vol.91 , pp. 932-944
    • Maejima, Y.1    Okada, H.2    Haraguchi, G.3    Onai, Y.4    Kosuge, H.5    Suzuki, J.6    Isobe, M.7
  • 19
    • 84896966584 scopus 로고    scopus 로고
    • Telmisartan exerts anti-tumor effects by activating peroxisome proliferator-activated receptor-α in human lung adenocarcinoma A 549 cells
    • Li J, Chen L, Yu P, Liu B, Zhu J and Yang Y: Telmisartan exerts anti-tumor effects by activating peroxisome proliferator-activated receptor.α in human lung adenocarcinoma A549 cells. Molecules 19: 2862-2876, 2014.
    • (2014) Molecules , vol.19 , pp. 2862-2876
    • Li, J.1    Chen, L.2    Yu, P.3    Liu, B.4    Zhu, J.5    Yang, Y.6
  • 20
    • 84928158353 scopus 로고    scopus 로고
    • PinX1 inhibits the invasion and metastasis of human breast cancer via suppressing NF-κB/MMP-9 signaling pathway
    • Shi M, Cao M, Song J, Liu Q, Li H, Meng F, Pan Z, Bai J and Zheng J: PinX1 inhibits the invasion and metastasis of human breast cancer via suppressing NF-κB/MMP-9 signaling pathway. Mol Cancer 14: 66, 2015.
    • (2015) Mol Cancer , vol.14 , pp. 66
    • Shi, M.1    Cao, M.2    Song, J.3    Liu, Q.4    Li, H.5    Meng, F.6    Pan, Z.7    Bai, J.8    Zheng, J.9
  • 24
    • 84899738340 scopus 로고    scopus 로고
    • Telmisartan induces growth inhibition, DNA double-strand breaks and apoptosis in human endometrial cancer cells
    • Koyama N, Nishida Y, Ishii T, Yoshida T, Furukawa Y and Narahara H: Telmisartan induces growth inhibition, DNA double-strand breaks and apoptosis in human endometrial cancer cells. PLoS One 9: e93050, 2014.
    • (2014) PLoS One , vol.9 , pp. e93050
    • Koyama, N.1    Nishida, Y.2    Ishii, T.3    Yoshida, T.4    Furukawa, Y.5    Narahara, H.6
  • 25
    • 0032588487 scopus 로고    scopus 로고
    • PPARgamma, the ultimate thrifty gene
    • Auwerx J: PPARgamma, the ultimate thrifty gene. Diabetologia 42: 1033-1049, 1999.
    • (1999) Diabetologia , vol.42 , pp. 1033-1049
    • Auwerx, J.1
  • 26
    • 27544433196 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors (PPARs) and ovarian function-implications for regulating steroidogenesis, differentiation and tissue remodeling
    • Komar CM: Peroxisome proliferator-activated receptors (PPARs) and ovarian function-implications for regulating steroidogenesis, differentiation and tissue remodeling. Reprod Biol Endocrinol 3: 41, 2005.
    • (2005) Reprod Biol Endocrinol , vol.3 , pp. 41
    • Komar, C.M.1
  • 27
    • 84901484832 scopus 로고    scopus 로고
    • Partial agonist, telmisartan, maintains PPARα serine 112 phosphorylation, and does not affect osteoblast differentiation and bone mass
    • Kolli V, Stechschulte LA, Dowling AR, Rahman S, Czernik PJ and Lecka-Czernik B: Partial agonist, telmisartan, maintains PPARα serine 112 phosphorylation, and does not affect osteoblast differentiation and bone mass. PLoS One 9: e96323, 2014.
    • (2014) PLoS One , vol.9 , pp. e96323
    • Kolli, V.1    Stechschulte, L.A.2    Dowling, A.R.3    Rahman, S.4    Czernik, P.J.5    Lecka-Czernik, B.6
  • 28
    • 84902255843 scopus 로고    scopus 로고
    • Telmisartan protects central neurons against nutrient deprivation-induced apoptosis in vitro through activation of PPARα and the Akt/GSK-3 β pathway
    • Pang T, Sun LX, Wang T, Jiang ZZ, Liao H and Zhang LY: Telmisartan protects central neurons against nutrient deprivation-induced apoptosis in vitro through activation of PPARα and the Akt/GSK-3 β pathway. Acta Pharmacol Sin 35: 727-737, 2014.
    • (2014) Acta Pharmacol Sin , vol.35 , pp. 727-737
    • Pang, T.1    Sun, L.X.2    Wang, T.3    Jiang, Z.Z.4    Liao, H.5    Zhang, L.Y.6
  • 29
    • 67651225196 scopus 로고    scopus 로고
    • Aspirin inhibits MMP-2 and MMP-9 expression and activity through PPARalpha/gamma and TIMP-1. Mediated mechanisms in cultured mouse celiac macrophages
    • Yiqin Y, Meilin X, Jie X and Keping Z: Aspirin inhibits MMP-2 and MMP-9 expression and activity through PPARalpha/gamma and TIMP-1. Mediated mechanisms in cultured mouse celiac macrophages. Inflammation 32: 233-241, 2009.
    • (2009) Inflammation , vol.32 , pp. 233-241
    • Yiqin, Y.1    Meilin, X.2    Jie, X.3    Keping, Z.4
  • 30
    • 69249143691 scopus 로고    scopus 로고
    • Telmisartan as a peroxisome proliferator-activated receptor-α ligand is a new target in the treatment of human renal cell carcinoma
    • Funao K, Matsuyama M, Kawahito Y, Sano H, Chargui J, Touraine JL, Nakatani T and Yoshimura R: Telmisartan as a peroxisome proliferator-activated receptor.α ligand is a new target in the treatment of human renal cell carcinoma. Mol Med Rep 2: 193-198, 2009.
    • (2009) Mol Med Rep , vol.2 , pp. 193-198
    • Funao, K.1    Matsuyama, M.2    Kawahito, Y.3    Sano, H.4    Chargui, J.5    Touraine, J.L.6    Nakatani, T.7    Yoshimura, R.8
  • 34
    • 84881458535 scopus 로고    scopus 로고
    • The protective effect of telmisartan in Type 2 diabetes rat kidneys is related to the downregulation of thioredoxin-interacting protein
    • Wu J, Lin H, Liu D, Liu J, Wang N, Mei X, Sun J, Yang G and Zhang X: The protective effect of telmisartan in Type 2 diabetes rat kidneys is related to the downregulation of thioredoxin-interacting protein. J Endocrinol Invest 36: 453-459, 2013.
    • (2013) J Endocrinol Invest , vol.36 , pp. 453-459
    • Wu, J.1    Lin, H.2    Liu, D.3    Liu, J.4    Wang, N.5    Mei, X.6    Sun, J.7    Yang, G.8    Zhang, X.9


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