Expression of peroxisome proliferators-activated receptor-γ and cyclooxygenase-2 in Helicobacter pylori infection-associated diseases and significance thereof

National Medical Journal of China

Volumn 86, Issue 38, 2006, Pages 2683-2689

  Xie, Yong ^a   Zhu, Jun ^a   Zhou, Xiao Jiang ^a   Chen, Jiang ^a   Lu, Nong Hua ^a   Wang, Chong Wen ^a  

^a NANCHANG UNIVERSITY   (China)

Author keywords

Epoxy compounds; Helicobacter pylori; PPAR

Indexed keywords

CYCLOOXYGENASE 2; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA;

ADULT; AGED; ARTICLE; ATROPHIC GASTRITIS; CHRONIC GASTRITIS; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE ASSOCIATION; DISEASE DURATION; DYSPLASIA; FEMALE; FOLLOW UP; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; HELICOBACTER INFECTION; HELICOBACTER PYLORI; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INFLAMMATORY CELL; INTESTINE METAPLASIA; MAJOR CLINICAL STUDY; MALE; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; STOMACH BIOPSY; STOMACH CARCINOGENESIS; STOMACH MUCOSA LESION;

ADULT; AGED; CYCLOOXYGENASE 2; FEMALE; FOLLOW-UP STUDIES; GASTRIC MUCOSA; GASTRITIS; GASTRITIS, ATROPHIC; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; PPAR GAMMA;

EID: 33845904633     PISSN: 03762491     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (11)

1. Nakajima A, Wada K, Miki H, et al. Endogenous PPAR gamma mediates anti-inflammatory activity in murine ischemia-reperfusion injury. Gastroenterology, 2001,120:460-469.
2. Harris SG, Phipps RP. The nuclear receptor PPAR gamma is expressed by mouse T lymphocytes and PPAR gamma agonists induce apoptosis. Eur J Immunol, 2001, 31:1098-1105.
3. Inoue H, Tanabe T, Umesono K. Feedback control of cyclooxygenase-2 expression through PPAR gamma. J Biol Chem, 2000, 275:28028-28032.
4. Chinese source. 2000,5:77-79.
5. Sasaki H, Nio M, Iwami D, et al. E-cadherin, alpha-catenin and beta-catenin in biliary atresia: correlation with apoptosis and cell cycle, Pathol Int, 2001,51:923-932.
6. Nakamura M, Takahashi S, Matsui H, et al. Persistent increase in myofibroblasts in Helicobacter Helimanniiinfected mice but not in Helicobacter pylori-infected Mongolian gerbils: colocalization of COX-2 and bFGF immunoreactivity. Aliment Pharmacol Ther, 2002, 16: 174-179.
7. Slomiany BL, Slomiany A. Suppression of Gastric Mucosal Inflammatory Responses to Helicobacter pylori Lipopolysaccharide by Peroxisome Proliferator-Activated Receptor γ Activation. IUBMB Life, 2002, 53:303-308.
8. Gupta RA, Polk DB, Krishna U, et al. Activation of peroxisome proliferators activated receptor-γ suppresses nuclear factor-κB - mediated apoptosis induced by Helicobacter pylori in gastric epithelial cells. J Biol Chem, 2001,276: 31059-31066.
9. Lefebvre AM, Chen I, Desreumaux P, et al. Activation of the peroxisome proliferator-activated receptor promotes the development of colon tumor in C57BL/6J-APCMin/ + mice. Nature Med, 1998, 4:1053-1057.
10. Meade EA, McIntyre TM, Zimmerman GA, et al. Peroxisome proliferators enhance cyclooxygenase-2 expression in epithelial cells. J Biol Chem, 1999, 274: 8328-8334.
11. Yeo M, Hahm KB. Role of COX-2 and PPAR in gastric carcinogenesis. Korean J Gastroenterol, 2004, 44:53-56.