Valproate attenuates diabetic nephropathy through inhibition of endoplasmic reticulum stress-induced apoptosis

Molecular Medicine Reports

Volumn 13, Issue 1, 2016, Pages 661-668

  Sun, Xin Yi ^a,b   Qin, Han Jiao ^c   Zhang, Ze ^c   Xu, Ye ^d   Yang, Xiao Chun ^a   Zhao, Dong Ming ^b   Li, Xiao Ning ^a   Sun, Lian Kun ^a  

^a JILIN UNIVERSITY   (China)

^b BEIHUA UNIVERSITY   (China)

^c Basic Medical College   (China)

^d JILIN MEDICAL COLLEGE   (China)

Author keywords

Apoptosis; Diabetic nephropathy; Endoplasmic reticulum stress; Histone acetylation; Valproate

Indexed keywords

CASPASE 12; CASPASE 3; CREATININE; DNA DAMAGE INDUCIBLE GENE 153; GLUCOSE REGULATED PROTEIN 78; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; HISTONE H4; PROTEIN; PROTEIN BAX; PROTEIN BCL 2; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; VALPROIC ACID; HEAT SHOCK PROTEIN; HISTONE; MOLECULAR CHAPERONE GRP78;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DIABETIC NEPHROPATHY; DOWN REGULATION; ENDOPLASMIC RETICULUM STRESS; GLOMERULUS BASEMENT MEMBRANE; HISTONE ACETYLATION; IMMUNOFLUORESCENCE MICROSCOPY; IMMUNOHISTOCHEMISTRY; IMMUNOHISTOLOGY; KIDNEY CELL; KIDNEY INJURY; KIDNEY MASS; KIDNEY PARENCHYMA; KIDNEY TUBULE; MALE; NONHUMAN; PROMOTER REGION; PROTEIN EXPRESSION; PROTEINURIA; RAT; TRANSMISSION ELECTRON MICROSCOPY; TUNEL ASSAY; WESTERN BLOTTING; ACETYLATION; ANIMAL; DIABETIC NEPHROPATHIES; DISEASE MODEL; DRUG EFFECTS; GENETICS; INJURIES; KIDNEY; METABOLISM; MITOCHONDRION; PATHOLOGY; WISTAR RAT;

ACETYLATION; ANIMALS; APOPTOSIS; DIABETIC NEPHROPATHIES; DISEASE MODELS, ANIMAL; ENDOPLASMIC RETICULUM STRESS; HEAT-SHOCK PROTEINS; HISTONES; KIDNEY; MALE; MITOCHONDRIA; PROMOTER REGIONS, GENETIC; RATS, WISTAR; TRANSCRIPTION FACTOR CHOP; VALPROIC ACID;

EID: 84954290734     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2015.4580     Document Type: Article

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