Doxorubicin-loaded biodegradable self-assembly zein nanoparticle and its anti-cancer effect: Preparation, in vitro evaluation, and cellular uptake

Colloids and Surfaces B: Biointerfaces

Volumn 140, Issue , 2016, Pages 324-331

  Dong, Fangyuan ^a,b   Dong, Xiaoli ^b   Zhou, Liping ^b   Xiao, Huihui ^a   Ho, Pui Yu ^b   Wong, Man Sau ^a,b   Wang, Yi ^a,b  

^a Shenzhen Key Laboratory of Food Biological Safety Control   (China)

^b HONG KONG POLYTECHNIC UNIVERSITY   (Hong Kong)

Author keywords

Cellular uptake; Doxorubicin; Drug delivery; Nano encapsulation; Zein

Indexed keywords

CONTROLLED DRUG DELIVERY; CYTOLOGY; DISEASES; DRUG DELIVERY; DRUG DOSAGE; EFFICIENCY; HIGH RESOLUTION TRANSMISSION ELECTRON MICROSCOPY; LANTHANUM COMPOUNDS; MOLECULAR BIOLOGY; NANOPARTICLES; SCANNING ELECTRON MICROSCOPY; SELF ASSEMBLY; ZEIN;

ANTI-CANCER THERAPIES; CELLULAR UPTAKE; CONFOCAL LASER SCANNING MICROSCOPY; DOXORUBICIN; ENCAPSULATION EFFICIENCY; ENDOCYTOSIS PATHWAY; NANO-ENCAPSULATION; SPHERICAL NANOPARTICLES;

TARGETED DRUG DELIVERY;

BUFFER; DOXORUBICIN; NANOPARTICLE; UNCLASSIFIED DRUG; ZEIN NANOPARTICLE; ANTINEOPLASTIC ANTIBIOTIC; ZEIN;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CANCER CELL DESTRUCTION; CELL KILLING; CELL TRANSPORT; CELL VIABILITY; CONFOCAL LASER MICROSCOPY; CYTOTOXICITY; DRUG FORMULATION; DRUG RELEASE; ENDOCYTOSIS; FLOW CYTOMETRY; HELA CELL LINE; IN VITRO STUDY; NANOENCAPSULATION; PH MEASUREMENT; PRIORITY JOURNAL; TRANSMISSION ELECTRON MICROSCOPY; CELL SURVIVAL; CHEMISTRY; CONFOCAL MICROSCOPY; DOSE RESPONSE; DRUG EFFECTS; HUMAN; PARTICLE SIZE; PH; PROCEDURES; SCANNING ELECTRON MICROSCOPY; ULTRASTRUCTURE;

ANTIBIOTICS, ANTINEOPLASTIC; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DOXORUBICIN; DRUG COMPOUNDING; DRUG LIBERATION; HELA CELLS; HUMANS; HYDROGEN-ION CONCENTRATION; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON, SCANNING; MICROSCOPY, ELECTRON, TRANSMISSION; NANOPARTICLES; PARTICLE SIZE; ZEIN;

EID: 84954290582     PISSN: 09277765     EISSN: 18734367     Source Type: Journal    
DOI: 10.1016/j.colsurfb.2015.12.048     Document Type: Article

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