Tumor associated macrophages provide the survival resistance of tumor cells to hypoxic microenvironmental condition through IL-6 receptor-mediated signals

Immunobiology

Volumn 222, Issue 1, 2017, Pages 55-65

  Jeong, Soo Kyung ^a,b   Kim, Joong Sun ^a   Lee, Chang Geun ^a   Park, You Soo ^a   Kim, Sung Dae ^a   Yoon, Sun Ok ^c   Han, Dong Hoon ^b   Lee, Kyu Yeol ^b   Jeong, Min Ho ^b   Jo, Wol Soon ^a  

^a Dongnam Institute of Radiological and Medical Science   (South Korea)

^b Dong A University College of Medicine   (South Korea)

^c Seoul National University College of Medicine   (South Korea)

Author keywords

Hypoxia; IL 6R; STAT3; Tumor microenvironment; Tumor associated macrophages

Indexed keywords

INTERLEUKIN 6 RECEPTOR; JANUS KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN BAK; PROTEIN BAX; PROTEIN BCL 2; RAF PROTEIN; SMALL INTERFERING RNA; STAT3 PROTEIN; STRESS ACTIVATED PROTEIN KINASE; CYTOKINE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CANCER CELL LINE; CELL DEATH; CELL INFILTRATION; CELL SURVIVAL; COCULTURE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOWN REGULATION; FEMALE; FM3A CELL LINE; GENE SILENCING; HUMAN; HUMAN CELL; HYPOXIA; MACROPHAGE; MCF 7 CELL LINE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; THP 1 CELL LINE; TUMOR ASSOCIATED LEUKOCYTE; TUMOR MICROENVIRONMENT; UPREGULATION; ANIMAL; BIOSYNTHESIS; CELL LINE; IMMUNOLOGY; MCF-7 CELL LINE; METABOLISM; NEOPLASM; PATHOLOGY;

ANIMALS; CELL LINE; CELL SURVIVAL; COCULTURE TECHNIQUES; CYTOKINES; FEMALE; HUMANS; HYPOXIA; MACROPHAGES; MCF-7 CELLS; MICE; NEOPLASMS; RECEPTORS, INTERLEUKIN-6; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; TUMOR MICROENVIRONMENT;

EID: 84954286671     PISSN: 01712985     EISSN: 18783279     Source Type: Journal    
DOI: 10.1016/j.imbio.2015.11.010     Document Type: Article

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