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Volumn 13, Issue 1, 2016, Pages 744-752

Downregulation of caveolin-1 upregulates the expression of growth factors and regulators in co-culture of fibroblasts with cancer cells

Author keywords

Breast cancer; Caveolin 1; Epidermal growth factor; Fibroblast; Fibroblast specific protein 1; Stromal cell derived factor 1; Tumor protein 53 induced glycolysis and apoptosis regulator

Indexed keywords

CALVASCULIN; CAVEOLIN 1; EPIDERMAL GROWTH FACTOR; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; STROMAL CELL DERIVED FACTOR 1; TUMOR PROTEIN; TUMOR PROTEIN 53 INDUCED GLYCOLYSIS AND APOPTOSIS REGULATOR; UNCLASSIFIED DRUG; C12ORF5 PROTEIN, HUMAN; CALCIUM BINDING PROTEIN; FSP1 PROTEIN, HUMAN; MESSENGER RNA; SIGNAL PEPTIDE;

EID: 84954271708     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2015.4610     Document Type: Article
Times cited : (23)

References (38)
  • 2
    • 79960393173 scopus 로고    scopus 로고
    • Caveolin-1 upregulation mediates suppression of primary breast tumor growth and brain metastases by stat3 inhibition
    • Chiu WT, Lee HT, Huang FJ, Aldape KD, Tao J, Steeg PS, Chou CY, Lu Z, Xie K and Huang S: Caveolin-1 upregulation mediates suppression of primary breast tumor growth and brain metastases by stat3 inhibition. Cancer Res 71: 4932-4943, 2011.
    • (2011) Cancer Res , vol.71 , pp. 4932-4943
    • Chiu, W.T.1    Lee, H.T.2    Huang, F.J.3    Aldape, K.D.4    Tao, J.5    Steeg, P.S.6    Chou, C.Y.7    Lu, Z.8    Xie, K.9    Huang, S.10
  • 3
    • 82855167795 scopus 로고    scopus 로고
    • Understanding the Warburg effect and the prognostic value of stromal caveolin-1 as a marker of a lethal tumor microenvironment
    • Sotgia F, Martinez-Outschoorn UE, Pavlides S, Howell A, Pestell RG and Lisanti MP: Understanding the Warburg effect and the prognostic value of stromal caveolin-1 as a marker of a lethal tumor microenvironment. Breast Cancer Res 13: 213-225, 2011.
    • (2011) Breast Cancer Res , vol.13 , pp. 213-225
    • Sotgia, F.1    Martinez-Outschoorn, U.E.2    Pavlides, S.3    Howell, A.4    Pestell, R.G.5    Lisanti, M.P.6
  • 7
    • 84910112545 scopus 로고    scopus 로고
    • Caveolin-1 limits the contribution of BKCa channel to MCF-7 breast cancer cell proliferation and invasion
    • Du C, Chen L, Zhang HJ, Wang ZC, Liu WC, Xie XD and Xie MJ: Caveolin-1 limits the contribution of BKCa channel to MCF-7 breast cancer cell proliferation and invasion. Int J Mol Sci 15: 20706-20722, 2014.
    • (2014) Int J Mol Sci , vol.15 , pp. 20706-20722
    • Du, C.1    Chen, L.2    Zhang, H.J.3    Wang, Z.C.4    Liu, W.C.5    Xie, X.D.6    Xie, M.J.7
  • 8
    • 84857640591 scopus 로고    scopus 로고
    • Cancer associated fibroblasts: The dark side of the coin
    • Paola C: Cancer associated fibroblasts: The dark side of the coin. Am J Cancer Res 1: 482-497, 2011.
    • (2011) Am J Cancer Res , vol.1 , pp. 482-497
    • Paola, C.1
  • 9
    • 79957774659 scopus 로고    scopus 로고
    • Why does chronic inflammation persist: An unexpected role for fibroblasts
    • Buckley CD: Why does chronic inflammation persist: An unexpected role for fibroblasts. Immunol Lett 138: 12-14, 2011.
    • (2011) Immunol Lett , vol.138 , pp. 12-14
    • Buckley, C.D.1
  • 11
    • 24744453768 scopus 로고    scopus 로고
    • Identification of novel p53 target genes in ionizing radiation response
    • Jen KY and Cheung VG: Identification of novel p53 target genes in ionizing radiation response. Cancer Res 65: 7666-7673, 2005.
    • (2005) Cancer Res , vol.65 , pp. 7666-7673
    • Jen, K.Y.1    Cheung, V.G.2
  • 13
    • 84945218064 scopus 로고    scopus 로고
    • Direct interaction between carcinoma cells and cancer associated fibroblasts for the regulation of cancer invasion
    • Yamaguchi H and Sakai R: Direct interaction between carcinoma cells and cancer associated fibroblasts for the regulation of cancer invasion. Cancers 7: 2054-2062, 2015.
    • (2015) Cancers , vol.7 , pp. 2054-2062
    • Yamaguchi, H.1    Sakai, R.2
  • 17
    • 84879096627 scopus 로고    scopus 로고
    • Overexpression of caveolin-1 in cancer-associated fibroblasts predicts good outcome in breast cancer
    • Shan-Wei W, Kan-Lun X, Shu-Qin R, Li-Li Z and Li-Rong C: Overexpression of caveolin-1 in cancer-associated fibroblasts predicts good outcome in breast cancer. Breast Care (Basel) 7: 477-483, 2012.
    • (2012) Breast Care (Basel) , vol.7 , pp. 477-483
    • Shan-Wei, W.1    Kan-Lun, X.2    Shu-Qin, R.3    Li-Li, Z.4    Li-Rong, C.5
  • 18
    • 68449103256 scopus 로고    scopus 로고
    • An absence of stromal caveolin-1 is associated with advanced prostate cancer, metastatic disease and epithelial Akt activation
    • Di Vizio D, Morello M, Sotgia F, Pestell RG, Freeman MR and Lisanti MP: An absence of stromal caveolin-1 is associated with advanced prostate cancer, metastatic disease and epithelial Akt activation. Cell Cycle 8: 2420-2424, 2009.
    • (2009) Cell Cycle , vol.8 , pp. 2420-2424
    • Di Vizio, D.1    Morello, M.2    Sotgia, F.3    Pestell, R.G.4    Freeman, M.R.5    Lisanti, M.P.6
  • 23
    • 84880430327 scopus 로고    scopus 로고
    • Role of oxidative stress and the microenvironment in breast cancer development and progression
    • Jezierska-Drutel A, Rosenzweig SA and Neumann CA: Role of oxidative stress and the microenvironment in breast cancer development and progression. Adv Cancer Res 119: 107-125, 2013.
    • (2013) Adv Cancer Res , vol.119 , pp. 107-125
    • Jezierska-Drutel, A.1    Rosenzweig, S.A.2    Neumann, C.A.3
  • 25
    • 17144410313 scopus 로고    scopus 로고
    • Akt activation,but not extracellular bignal-reguhted kinase activation,is required for SDF-lalpha/CXCR4-mediated migration of epitheloid carcinoma cells
    • Peng SB, Peek V, Zhai Y, Paul DC, Lou Q, Xia X, Eesalu T, Kohn W and Tang S: Akt activation,but not extracellular bignal-reguhted kinase activation,is required for SDF-lalpha/CXCR4-mediated migration of epitheloid carcinoma cells. Mol Cancer Res 3: 227-236, 2005.
    • (2005) Mol Cancer Res , vol.3 , pp. 227-236
    • Peng, S.B.1    Peek, V.2    Zhai, Y.3    Paul, D.C.4    Lou, Q.5    Xia, X.6    Eesalu, T.7    Kohn, W.8    Tang, S.9
  • 26
    • 18844428327 scopus 로고    scopus 로고
    • Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCLl2 secretion
    • Orimo A, Gupta PB, Sgroi DC, Arenzana-Seisdedos F, Delaunay T, Naeem R, Carey VJ, Richardson AL and Weinberg RA: Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCLl2 secretion. Cell 121: 335-348, 2005.
    • (2005) Cell , vol.121 , pp. 335-348
    • Orimo, A.1    Gupta, P.B.2    Sgroi, D.C.3    Arenzana-Seisdedos, F.4    Delaunay, T.5    Naeem, R.6    Carey, V.J.7    Richardson, A.L.8    Weinberg, R.A.9
  • 28
    • 84860387377 scopus 로고    scopus 로고
    • Attractive guidance: How the chemokine SDF1/CXCL12 guides different cells to different locations
    • Lewellis SW and Knaut H: Attractive guidance: how the chemokine SDF1/CXCL12 guides different cells to different locations. Semin Cell Dev Bio 23: 333-340, 2012.
    • (2012) Semin Cell Dev Bio , vol.23 , pp. 333-340
    • Lewellis, S.W.1    Knaut, H.2
  • 29
    • 2342591450 scopus 로고    scopus 로고
    • The significance of cancer cell expression of the chemokine receptor CXCR4
    • Balkwill F: The significance of cancer cell expression of the chemokine receptor CXCR4. Semin Cancer Biol 14: 171-179, 2004.
    • (2004) Semin Cancer Biol , vol.14 , pp. 171-179
    • Balkwill, F.1
  • 31
    • 67449119735 scopus 로고    scopus 로고
    • Relationship between VEGF, EGF and invasion, metastasis of gastric cancer cells
    • Li CF, Ma Y, Wei YZ and Xue Y: Relationship between VEGF, EGF and invasion, metastasis of gastric cancer cells. Chin J Cancer Res 21: 122-129, 2009.
    • (2009) Chin J Cancer Res , vol.21 , pp. 122-129
    • Li, C.F.1    Ma, Y.2    Wei, Y.Z.3    Xue, Y.4
  • 32
    • 59249088928 scopus 로고    scopus 로고
    • EGF stimulates uPAR expression and cell invasiveness through ERK, AP-l, and NF-kappaB signaling in human gastric carcinoma cells
    • Baek MK, Kim MH, Jang HJ, Park JS, Chung IJ, Shin BA, Ahn BW and Jung YD: EGF stimulates uPAR expression and cell invasiveness through ERK, AP-l, and NF-kappaB signaling in human gastric carcinoma cells. Oncol Rep 20: 1569-1575, 2008.
    • (2008) Oncol Rep , vol.20 , pp. 1569-1575
    • Baek, M.K.1    Kim, M.H.2    Jang, H.J.3    Park, J.S.4    Chung, I.J.5    Shin, B.A.6    Ahn, B.W.7    Jung, Y.D.8
  • 33
    • 45249103749 scopus 로고    scopus 로고
    • Epidermal growth factor therapy and wound healing-past, present and future perspectives
    • Hardwicke J, Schmaljohann D, Boyce D and Thomas D: Epidermal growth factor therapy and wound healing-past, present and future perspectives. Surgeon 6: 172-177, 2008.
    • (2008) Surgeon , vol.6 , pp. 172-177
    • Hardwicke, J.1    Schmaljohann, D.2    Boyce, D.3    Thomas, D.4
  • 34
    • 21244446530 scopus 로고    scopus 로고
    • The metastasis associated protein S100A4: Role in tumour progression and metastasis
    • Helfman DM, Kim EJ, Lukanidin E and Grigorian M: The metastasis associated protein S100A4: role in tumour progression and metastasis. Br J Cancer 92: 1955-1958, 2005.
    • (2005) Br J Cancer , vol.92 , pp. 1955-1958
    • Helfman, D.M.1    Kim, E.J.2    Lukanidin, E.3    Grigorian, M.4
  • 37
    • 33745713432 scopus 로고    scopus 로고
    • P53 and metabolism: Inside the TIGAR
    • Green DR and Chipuk JE: p53 and metabolism: Inside the TIGAR. Cell 126: 30-32, 2006.
    • (2006) Cell , vol.126 , pp. 30-32
    • Green, D.R.1    Chipuk, J.E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.