Discovery of a Direct Ras Inhibitor by Screening a Combinatorial Library of Cell-Permeable Bicyclic Peptides

ACS Combinatorial Science

Volumn 18, Issue 1, 2016, Pages 75-85

  Trinh, Thi B ^a   Upadhyaya, Punit ^a   Qian, Ziqing ^a   Pei, Dehua ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

anticancer agent; bicyclic peptide; cell penetrating peptide; peptide library; Ras inhibitor

Indexed keywords

ANTINEOPLASTIC AGENT; CELL PENETRATING PEPTIDE; CYCLOPEPTIDE; PEPTIDE LIBRARY; RAS PROTEIN;

ANTAGONISTS AND INHIBITORS; CHEMISTRY; DRUG EFFECTS; GENETICS; HUMAN; LUNG; LUNG NEOPLASMS; METABOLISM; PEPTIDE LIBRARY; POINT MUTATION; SIGNAL TRANSDUCTION; SYNTHESIS; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL-PENETRATING PEPTIDES; HUMANS; LUNG; LUNG NEOPLASMS; PEPTIDE LIBRARY; PEPTIDES, CYCLIC; POINT MUTATION; RAS PROTEINS; SIGNAL TRANSDUCTION;

EID: 84954178710     PISSN: 21568952     EISSN: None     Source Type: Journal    
DOI: 10.1021/acscombsci.5b00164     Document Type: Article

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