BRAFV600E inhibition stimulates AMP-activated protein kinase-mediated autophagy in colorectal cancer cells

Scientific Reports

Volumn 6, Issue , 2016, Pages

  Sueda, Toshinori ^a   Sakai, Daisuke ^a   Kawamoto, Koichi ^a   Konno, Masamitsu ^a   Nishida, Naohiro ^a   Koseki, Jun ^a   Colvin, Hugh ^a   Takahashi, Hidekazu ^a   Haraguchi, Naotsugu ^a   Nishimura, Junichi ^a   Hata, Taishi ^a   Takemasa, Ichiro ^a   Mizushima, Tsunekazu ^a   Yamamoto, Hirofumi ^a   Satoh, Taroh ^a   Doki, Yuichiro ^a   Mori, Masaki ^a   Ishii, Hideshi ^a  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; B RAF KINASE; BRAF PROTEIN, HUMAN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INDOLE DERIVATIVE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE; N [3 (5 CHLORO 1H PYRROLO[2,3 B]PYRIDINE 3 CARBONYL) 2,4 DIFLUOROPHENYL]PROPANESULFONAMIDE; SMALL INTERFERING RNA; SULFONAMIDE; VEMURAFENIB;

ANIMAL; ANTAGONISTS AND INHIBITORS; AUTOPHAGY; BAGG ALBINO MOUSE; CACO-2 CELL LINE; COLORECTAL NEOPLASMS; DRUG SCREENING; FEMALE; GENE EXPRESSION REGULATION; GENETICS; HT-29 CELL LINE; HUMAN; METABOLISM; MOUSE; MUTATION; NUDE MOUSE; PATHOLOGY; SIGNAL TRANSDUCTION; SUBCUTANEOUS DRUG ADMINISTRATION; TUMOR CELL LINE;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; ANTINEOPLASTIC AGENTS; AUTOPHAGY; CACO-2 CELLS; CELL LINE, TUMOR; COLORECTAL NEOPLASMS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HT29 CELLS; HUMANS; INDOLES; INJECTIONS, SUBCUTANEOUS; MAP KINASE KINASE KINASES; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED BALB C; MICE, NUDE; MUTATION; PROTO-ONCOGENE PROTEINS B-RAF; RNA, SMALL INTERFERING; SULFONAMIDES; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84954162162     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep18949     Document Type: Article

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